Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin)

Moutawakilou Gomina; Moussa Ayedoun; Tarik Salifou; Delphin Aidewou; Simon Akpona

doi:doi:10.11648/j.ab.20200801.12

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Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin)

Moutawakilou Gomina, Moussa Ayedoun, Tarik Salifou, Delphin Aidewou, Simon Akpona

Published in Advances in Biochemistry (Volume 8, Issue 1)

Received: 21 December 2019 Accepted: 30 December 2019 Published: 7 January 2020

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Abstract

Objective: Determine the prevalence and factors associated with dyslipidemia in adult subjects with sickle cell disease in Parakou in 2017. Methods: This research work was a descriptive, analytical, cross-sectional and observational study carried out from January 6 to June 6, 2017. It involved 100 adult subjects with sickle cell disease (mean age: 28.77 ± 8.73 years) in the city of Parakou (Benin). Serum lipid parameters were measured through enzymatic colorimetric methods on Mindray ® BS-120 automaton (Guangdong, China). The different types of dyslipidemia were classified according to criteria defined in the National Cholesterol Education Program Adult Treatment Panel III. Results: The overall prevalence of the different types of dyslipidemia was estimated at 82% (95% CI [75.27; 88.34]). The different types of dyslipidemia were distributed as followed: HDL hypocholesterolemia (79%; 95%IC [69.71; 86.51]), LDL hypercholesterolemia (13.0%; 95%CI [7.11; 21.20]), total hypercholesterolemia (7.0%; 95%CI [02.86; 13.89]), hypertriglyceridemia (4.0%; 95%CI [1.10; 9.93]) and mixed hyperlipidemia (1.0%; 95%CI [0.03; 5.45]). Atherogenic dyslipidemia was not found out. HDL hypocholesterolemia was significantly associated with personal history of hypertension (P = 0.029), emaciation (P = 0.023) and age above or equal to 50 years (P = 0,016). Tobacco consumption (P = 0.01) and age below 50 years (P = 0.02) were significantly associated with hypertriglyceridemia. Conclusion: The prevalence of the different types of dyslipidemia is high among adults with sickle cell disease in Parakou.

Published in	Advances in Biochemistry (Volume 8, Issue 1)
DOI	10.11648/j.ab.20200801.12
Page(s)	11-15
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Dyslipidemia, Hypercholesterolemia, Sickle Cell Disease, Benin

References

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APA Style

Moutawakilou Gomina, Moussa Ayedoun, Tarik Salifou, Delphin Aidewou, Simon Akpona. (2020). Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin). Advances in Biochemistry, 8(1), 11-15. https://doi.org/10.11648/j.ab.20200801.12

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ACS Style

Moutawakilou Gomina; Moussa Ayedoun; Tarik Salifou; Delphin Aidewou; Simon Akpona. Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin). Adv. Biochem. 2020, 8(1), 11-15. doi: 10.11648/j.ab.20200801.12

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AMA Style

Moutawakilou Gomina, Moussa Ayedoun, Tarik Salifou, Delphin Aidewou, Simon Akpona. Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin). Adv Biochem. 2020;8(1):11-15. doi: 10.11648/j.ab.20200801.12

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@article{10.11648/j.ab.20200801.12,
  author = {Moutawakilou Gomina and Moussa Ayedoun and Tarik Salifou and Delphin Aidewou and Simon Akpona},
  title = {Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin)},
  journal = {Advances in Biochemistry},
  volume = {8},
  number = {1},
  pages = {11-15},
  doi = {10.11648/j.ab.20200801.12},
  url = {https://doi.org/10.11648/j.ab.20200801.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20200801.12},
  abstract = {Objective: Determine the prevalence and factors associated with dyslipidemia in adult subjects with sickle cell disease in Parakou in 2017. Methods: This research work was a descriptive, analytical, cross-sectional and observational study carried out from January 6 to June 6, 2017. It involved 100 adult subjects with sickle cell disease (mean age: 28.77 ± 8.73 years) in the city of Parakou (Benin). Serum lipid parameters were measured through enzymatic colorimetric methods on Mindray ® BS-120 automaton (Guangdong, China). The different types of dyslipidemia were classified according to criteria defined in the National Cholesterol Education Program Adult Treatment Panel III. Results: The overall prevalence of the different types of dyslipidemia was estimated at 82% (95% CI [75.27; 88.34]). The different types of dyslipidemia were distributed as followed: HDL hypocholesterolemia (79%; 95%IC [69.71; 86.51]), LDL hypercholesterolemia (13.0%; 95%CI [7.11; 21.20]), total hypercholesterolemia (7.0%; 95%CI [02.86; 13.89]), hypertriglyceridemia (4.0%; 95%CI [1.10; 9.93]) and mixed hyperlipidemia (1.0%; 95%CI [0.03; 5.45]). Atherogenic dyslipidemia was not found out. HDL hypocholesterolemia was significantly associated with personal history of hypertension (P = 0.029), emaciation (P = 0.023) and age above or equal to 50 years (P = 0,016). Tobacco consumption (P = 0.01) and age below 50 years (P = 0.02) were significantly associated with hypertriglyceridemia. Conclusion: The prevalence of the different types of dyslipidemia is high among adults with sickle cell disease in Parakou.},
 year = {2020}
}

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TY  - JOUR
T1  - Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin)
AU  - Moutawakilou Gomina
AU  - Moussa Ayedoun
AU  - Tarik Salifou
AU  - Delphin Aidewou
AU  - Simon Akpona
Y1  - 2020/01/07
PY  - 2020
N1  - https://doi.org/10.11648/j.ab.20200801.12
DO  - 10.11648/j.ab.20200801.12
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 11
EP  - 15
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20200801.12
AB  - Objective: Determine the prevalence and factors associated with dyslipidemia in adult subjects with sickle cell disease in Parakou in 2017. Methods: This research work was a descriptive, analytical, cross-sectional and observational study carried out from January 6 to June 6, 2017. It involved 100 adult subjects with sickle cell disease (mean age: 28.77 ± 8.73 years) in the city of Parakou (Benin). Serum lipid parameters were measured through enzymatic colorimetric methods on Mindray ® BS-120 automaton (Guangdong, China). The different types of dyslipidemia were classified according to criteria defined in the National Cholesterol Education Program Adult Treatment Panel III. Results: The overall prevalence of the different types of dyslipidemia was estimated at 82% (95% CI [75.27; 88.34]). The different types of dyslipidemia were distributed as followed: HDL hypocholesterolemia (79%; 95%IC [69.71; 86.51]), LDL hypercholesterolemia (13.0%; 95%CI [7.11; 21.20]), total hypercholesterolemia (7.0%; 95%CI [02.86; 13.89]), hypertriglyceridemia (4.0%; 95%CI [1.10; 9.93]) and mixed hyperlipidemia (1.0%; 95%CI [0.03; 5.45]). Atherogenic dyslipidemia was not found out. HDL hypocholesterolemia was significantly associated with personal history of hypertension (P = 0.029), emaciation (P = 0.023) and age above or equal to 50 years (P = 0,016). Tobacco consumption (P = 0.01) and age below 50 years (P = 0.02) were significantly associated with hypertriglyceridemia. Conclusion: The prevalence of the different types of dyslipidemia is high among adults with sickle cell disease in Parakou.
VL  - 8
IS  - 1
ER  -

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Author Information

Moutawakilou Gomina

Unit for Training & Research in Biochemistry, Faculty of Medicine, University of Parakou, Parakou, Benin
Moussa Ayedoun

Unit for Training & Research in Biochemistry, Faculty of Medicine, University of Parakou, Parakou, Benin
Tarik Salifou

Unit for Training & Research in Biochemistry, Faculty of Medicine, University of Parakou, Parakou, Benin
Delphin Aidewou

Borgou Regional Branch of the National Agency for Blood Transfusion, Parakou, Benin
Simon Akpona

Unit for Training & Research in Biochemistry, Faculty of Medicine, University of Parakou, Parakou, Benin

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APA Style

Moutawakilou Gomina, Moussa Ayedoun, Tarik Salifou, Delphin Aidewou, Simon Akpona. (2020). Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin). Advances in Biochemistry, 8(1), 11-15. https://doi.org/10.11648/j.ab.20200801.12

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ACS Style

Moutawakilou Gomina; Moussa Ayedoun; Tarik Salifou; Delphin Aidewou; Simon Akpona. Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin). Adv. Biochem. 2020, 8(1), 11-15. doi: 10.11648/j.ab.20200801.12

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AMA Style

Moutawakilou Gomina, Moussa Ayedoun, Tarik Salifou, Delphin Aidewou, Simon Akpona. Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin). Adv Biochem. 2020;8(1):11-15. doi: 10.11648/j.ab.20200801.12

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@article{10.11648/j.ab.20200801.12,
  author = {Moutawakilou Gomina and Moussa Ayedoun and Tarik Salifou and Delphin Aidewou and Simon Akpona},
  title = {Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin)},
  journal = {Advances in Biochemistry},
  volume = {8},
  number = {1},
  pages = {11-15},
  doi = {10.11648/j.ab.20200801.12},
  url = {https://doi.org/10.11648/j.ab.20200801.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20200801.12},
  abstract = {Objective: Determine the prevalence and factors associated with dyslipidemia in adult subjects with sickle cell disease in Parakou in 2017. Methods: This research work was a descriptive, analytical, cross-sectional and observational study carried out from January 6 to June 6, 2017. It involved 100 adult subjects with sickle cell disease (mean age: 28.77 ± 8.73 years) in the city of Parakou (Benin). Serum lipid parameters were measured through enzymatic colorimetric methods on Mindray ® BS-120 automaton (Guangdong, China). The different types of dyslipidemia were classified according to criteria defined in the National Cholesterol Education Program Adult Treatment Panel III. Results: The overall prevalence of the different types of dyslipidemia was estimated at 82% (95% CI [75.27; 88.34]). The different types of dyslipidemia were distributed as followed: HDL hypocholesterolemia (79%; 95%IC [69.71; 86.51]), LDL hypercholesterolemia (13.0%; 95%CI [7.11; 21.20]), total hypercholesterolemia (7.0%; 95%CI [02.86; 13.89]), hypertriglyceridemia (4.0%; 95%CI [1.10; 9.93]) and mixed hyperlipidemia (1.0%; 95%CI [0.03; 5.45]). Atherogenic dyslipidemia was not found out. HDL hypocholesterolemia was significantly associated with personal history of hypertension (P = 0.029), emaciation (P = 0.023) and age above or equal to 50 years (P = 0,016). Tobacco consumption (P = 0.01) and age below 50 years (P = 0.02) were significantly associated with hypertriglyceridemia. Conclusion: The prevalence of the different types of dyslipidemia is high among adults with sickle cell disease in Parakou.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Prevalence and Factors Associated with Dyslipidemia in Adults with Sickle Cell Disease in Parakou (Benin)
AU  - Moutawakilou Gomina
AU  - Moussa Ayedoun
AU  - Tarik Salifou
AU  - Delphin Aidewou
AU  - Simon Akpona
Y1  - 2020/01/07
PY  - 2020
N1  - https://doi.org/10.11648/j.ab.20200801.12
DO  - 10.11648/j.ab.20200801.12
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 11
EP  - 15
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20200801.12
AB  - Objective: Determine the prevalence and factors associated with dyslipidemia in adult subjects with sickle cell disease in Parakou in 2017. Methods: This research work was a descriptive, analytical, cross-sectional and observational study carried out from January 6 to June 6, 2017. It involved 100 adult subjects with sickle cell disease (mean age: 28.77 ± 8.73 years) in the city of Parakou (Benin). Serum lipid parameters were measured through enzymatic colorimetric methods on Mindray ® BS-120 automaton (Guangdong, China). The different types of dyslipidemia were classified according to criteria defined in the National Cholesterol Education Program Adult Treatment Panel III. Results: The overall prevalence of the different types of dyslipidemia was estimated at 82% (95% CI [75.27; 88.34]). The different types of dyslipidemia were distributed as followed: HDL hypocholesterolemia (79%; 95%IC [69.71; 86.51]), LDL hypercholesterolemia (13.0%; 95%CI [7.11; 21.20]), total hypercholesterolemia (7.0%; 95%CI [02.86; 13.89]), hypertriglyceridemia (4.0%; 95%CI [1.10; 9.93]) and mixed hyperlipidemia (1.0%; 95%CI [0.03; 5.45]). Atherogenic dyslipidemia was not found out. HDL hypocholesterolemia was significantly associated with personal history of hypertension (P = 0.029), emaciation (P = 0.023) and age above or equal to 50 years (P = 0,016). Tobacco consumption (P = 0.01) and age below 50 years (P = 0.02) were significantly associated with hypertriglyceridemia. Conclusion: The prevalence of the different types of dyslipidemia is high among adults with sickle cell disease in Parakou.
VL  - 8
IS  - 1
ER  -

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