The objective of this article is to evaluate emmenagogue activity aqueous extract of Cajanus cajan (fabaceae) leaves in rat. 100 g of leaves powder of Cajanus cajan were added 1 liter from distilled water and mixes it was carried to boiling then filtered. The filtrate was dried with the drying oven, the dried filtrate constitutes the aqueous extract (AECc). For the evaluation of emmenagogue activity, the rates in pseudogestation were used. These rates was obtained by coupling nulliparous and pubescent rates with vasectomized rats (rats made sterile by binding of vas deferens). AECc was managed with the amounts from 12,5 to 600 mg/kg of body weight, as well as the misoprostol with the amount of 2 mg/kg of body weight by oral way. The uterus and blood were taken for respectively the determination of the average weight and for the proportioning of progesterone. The results showed a variation of uterus weight as well as a variation of serum progesterone concentration at rate. AECc effect on the progesterone rate at the rate in pseudogestation gave a significant decrease (p<0.001) progesterone rate to amounts 100; 200; 400 and 600 mg/kg bw compared to control. As for amounts 12.5; 25; and 50 mg/kg bw, the aqueous extract decreased the progesterone rate in a nonsignificant way compared to the control. The aqueous extract of Cajanus cajan thus supports the menstruation with the amounts from 100 to 600 mg/kg bw and relieves of the painful rules to amounts 12.5 to 50 mg/kg bw.
| Published in | Advances in Biochemistry (Volume 11, Issue 1) |
| DOI | 10.11648/j.ab.20231101.11 |
| Page(s) | 1-7 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Cajanus cajan, Emmenagogue, Progesterone
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APA Style
Zokore Zazou Ange Kevin, Kouakou Koffi Roger, Droucoula Guillaume Cyril, Yapo Adou Francis. (2023). Evaluation of Emmenagogue Activity of Aqueous Extract of Cajanus Cajan (Fabaceae) Leaves. Advances in Biochemistry, 11(1), 1-7. https://doi.org/10.11648/j.ab.20231101.11
ACS Style
Zokore Zazou Ange Kevin; Kouakou Koffi Roger; Droucoula Guillaume Cyril; Yapo Adou Francis. Evaluation of Emmenagogue Activity of Aqueous Extract of Cajanus Cajan (Fabaceae) Leaves. Adv. Biochem. 2023, 11(1), 1-7. doi: 10.11648/j.ab.20231101.11
AMA Style
Zokore Zazou Ange Kevin, Kouakou Koffi Roger, Droucoula Guillaume Cyril, Yapo Adou Francis. Evaluation of Emmenagogue Activity of Aqueous Extract of Cajanus Cajan (Fabaceae) Leaves. Adv Biochem. 2023;11(1):1-7. doi: 10.11648/j.ab.20231101.11
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Download@article{10.11648/j.ab.20231101.11,
author = {Zokore Zazou Ange Kevin and Kouakou Koffi Roger and Droucoula Guillaume Cyril and Yapo Adou Francis},
title = {Evaluation of Emmenagogue Activity of Aqueous Extract of Cajanus Cajan (Fabaceae) Leaves},
journal = {Advances in Biochemistry},
volume = {11},
number = {1},
pages = {1-7},
doi = {10.11648/j.ab.20231101.11},
url = {https://doi.org/10.11648/j.ab.20231101.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20231101.11},
abstract = {The objective of this article is to evaluate emmenagogue activity aqueous extract of Cajanus cajan (fabaceae) leaves in rat. 100 g of leaves powder of Cajanus cajan were added 1 liter from distilled water and mixes it was carried to boiling then filtered. The filtrate was dried with the drying oven, the dried filtrate constitutes the aqueous extract (AECc). For the evaluation of emmenagogue activity, the rates in pseudogestation were used. These rates was obtained by coupling nulliparous and pubescent rates with vasectomized rats (rats made sterile by binding of vas deferens). AECc was managed with the amounts from 12,5 to 600 mg/kg of body weight, as well as the misoprostol with the amount of 2 mg/kg of body weight by oral way. The uterus and blood were taken for respectively the determination of the average weight and for the proportioning of progesterone. The results showed a variation of uterus weight as well as a variation of serum progesterone concentration at rate. AECc effect on the progesterone rate at the rate in pseudogestation gave a significant decrease (pCajanus cajan thus supports the menstruation with the amounts from 100 to 600 mg/kg bw and relieves of the painful rules to amounts 12.5 to 50 mg/kg bw.},
year = {2023}
}
TY - JOUR T1 - Evaluation of Emmenagogue Activity of Aqueous Extract of Cajanus Cajan (Fabaceae) Leaves AU - Zokore Zazou Ange Kevin AU - Kouakou Koffi Roger AU - Droucoula Guillaume Cyril AU - Yapo Adou Francis Y1 - 2023/02/14 PY - 2023 N1 - https://doi.org/10.11648/j.ab.20231101.11 DO - 10.11648/j.ab.20231101.11 T2 - Advances in Biochemistry JF - Advances in Biochemistry JO - Advances in Biochemistry SP - 1 EP - 7 PB - Science Publishing Group SN - 2329-0862 UR - https://doi.org/10.11648/j.ab.20231101.11 AB - The objective of this article is to evaluate emmenagogue activity aqueous extract of Cajanus cajan (fabaceae) leaves in rat. 100 g of leaves powder of Cajanus cajan were added 1 liter from distilled water and mixes it was carried to boiling then filtered. The filtrate was dried with the drying oven, the dried filtrate constitutes the aqueous extract (AECc). For the evaluation of emmenagogue activity, the rates in pseudogestation were used. These rates was obtained by coupling nulliparous and pubescent rates with vasectomized rats (rats made sterile by binding of vas deferens). AECc was managed with the amounts from 12,5 to 600 mg/kg of body weight, as well as the misoprostol with the amount of 2 mg/kg of body weight by oral way. The uterus and blood were taken for respectively the determination of the average weight and for the proportioning of progesterone. The results showed a variation of uterus weight as well as a variation of serum progesterone concentration at rate. AECc effect on the progesterone rate at the rate in pseudogestation gave a significant decrease (pCajanus cajan thus supports the menstruation with the amounts from 100 to 600 mg/kg bw and relieves of the painful rules to amounts 12.5 to 50 mg/kg bw. VL - 11 IS - 1 ER -
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