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Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise

Received: 2 September 2019     Accepted: 23 September 2019     Published: 9 October 2019
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Abstract

To study the effects of astaxanthin supplementation on serum antioxidant capacity, blood lactic acid and blood uric acid metabolism of human body in the 1h recovery period after acute high-intensity exercise. Sixteen male students grade 2016 from Physical Education Institution (age: 19.13±2.52, height: 179±4.21cm and weight 68.23±7.81kg) were randomly divided into two groups: group A (experimental) and B (control). Group A was given astaxanthin for 28 days at a moderate dose (12 mg/d) and placebo for 28 days at group B. 4 weeks later, all subjects underwent exercise on power bike. The antioxidant capacity and blood uric acid and the content of blood lactic acid was assayed using anti-oxidation Kit (FORD), blood lactic acid Kit (LACTIC ACID), blood uric acid Kit (URIC ACID). Results: 1) One hour after exercise, the antioxidant capacity in both A and B obviously increased without exception and the value of group A was obviously higher than B. The blood lactic acid in both groups dramatically declined and the value of group A was obviously lower than B. The blood uric acid rised in both groups and the value of A was obviously lower than B. Conclusions: Pre-supplement of astaxanthin can accelerate the recovery of antioxidant capacity, accelerate the clearance of blood lactate and delay the increase of blood uric acid in the body within 1 hour after exercise.

Published in Advances in Bioscience and Bioengineering (Volume 7, Issue 4)
DOI 10.11648/j.abb.20190704.11
Page(s) 60-63
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Astaxanthin, Exercise Recovery, Antioxidant Capacity, Blood Lactic Acid, Blood Uric Acid

References
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[3] HÖhn, A., KÖnig, J., Grune, T. (2013). Protein oxidation in aging and the removal of oxidized proteins. Journal of Proteomics. 92, 132-159.
[4] Ambati, R. R., Siew, M. P., Ravi, S. (2014) Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review. Marine Drugs 12 (1): 128-152.
[5] Polotow, T. G., Vardaris, C. V., Mihaliuc, A. R., Gonçalves, M. S., Pereira, Ganini., Barros, M. P. (2014) Astaxanthin Supplementation Delays Physical Exhaustion and Prevents Redox Imbalances in Plasma and Soleus Muscles of Wistar Rats. Nutrients. 6 (12): 5819-5838.
[6] Fumio, S., TakayaA, O., Mutsuki, I. (2015). Effects of Daily Astaxanthin and L-carnitine Supplementation for Exercise Induced Muscle Damage in Training Thoroughbred Horses. Journal of Equine Veterinary Science. 35 (10): 836–842.
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[8] Ayano, I., Yuriko, O., Naoki, T., Shinobu, S., Kiyotaka, N., Teruo, M., Fumitaka, U. (2018). Effects of Dietary Supplementation of Astaxanthin and Sesamin on Daily Fatigue: A Randomized, Double-Blind, Placebo -Controlled, Two-Way Crossover Study. Nutrients. 10 (3): 281.
[9] Maki, T., Wataru, A., Hitomi, T., Yuko, T., Sayori, W., Akane, H. (2019). Effect of dietary antioxidant-rich foods combined with aerobic training on energy metabolism in healthy young men. J Clin Biochem Nutr. 64 (1): 79–85.
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[11] Lijun Wu, Zhuo Sun, An’ping Chen, Xinming Guo, Jie Wang. (2018). Effect of astaxanthin and exercise on antioxidant capacity of human body, blood lactic acid and blood uric acid metabolism. Science & Sports. doi.org/10.1016/j.scispo.2018.12.008.
[12] Katrin, P., Michael, R., Katrin, S., Kathrin, R. S., Marina, K. (2015). Lactic acid delays the inflammatory response of human monocytes. Biochemical and Biophysical Research Communications. 457: 412-418.
[13] Yuichiro Nishida, Minko Iyadomi, Yasuki Higai, Hiroaki Tanaka, Megumi Hara, Keitaro Tanka. (2011). Influence of Physical Activity Intensity and Aerobic Fitness on the Anthropometric Index and Serum Uric Acid Concentration in People with Obesity. Internal Medicine. 50: 2121-2128.
[14] Lamina, S., Okoye, G. C. (2012). Effects of Aerobic Exercise Training on Psychosocial Status and Serum Uric Acid in Men with Essential Hypertension: A Randomized Controlled Trial. Annals of Medical and Health Sciences Research. 2 (2): 161-168.
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  • APA Style

    Lijun Wu, Zhuo Sun, Jing Zhao, Xinming Guo, Jie Wang. (2019). Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise. Advances in Bioscience and Bioengineering, 7(4), 60-63. https://doi.org/10.11648/j.abb.20190704.11

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    ACS Style

    Lijun Wu; Zhuo Sun; Jing Zhao; Xinming Guo; Jie Wang. Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise. Adv. BioSci. Bioeng. 2019, 7(4), 60-63. doi: 10.11648/j.abb.20190704.11

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    AMA Style

    Lijun Wu, Zhuo Sun, Jing Zhao, Xinming Guo, Jie Wang. Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise. Adv BioSci Bioeng. 2019;7(4):60-63. doi: 10.11648/j.abb.20190704.11

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  • @article{10.11648/j.abb.20190704.11,
      author = {Lijun Wu and Zhuo Sun and Jing Zhao and Xinming Guo and Jie Wang},
      title = {Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise},
      journal = {Advances in Bioscience and Bioengineering},
      volume = {7},
      number = {4},
      pages = {60-63},
      doi = {10.11648/j.abb.20190704.11},
      url = {https://doi.org/10.11648/j.abb.20190704.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.abb.20190704.11},
      abstract = {To study the effects of astaxanthin supplementation on serum antioxidant capacity, blood lactic acid and blood uric acid metabolism of human body in the 1h recovery period after acute high-intensity exercise. Sixteen male students grade 2016 from Physical Education Institution (age: 19.13±2.52, height: 179±4.21cm and weight 68.23±7.81kg) were randomly divided into two groups: group A (experimental) and B (control). Group A was given astaxanthin for 28 days at a moderate dose (12 mg/d) and placebo for 28 days at group B. 4 weeks later, all subjects underwent exercise on power bike. The antioxidant capacity and blood uric acid and the content of blood lactic acid was assayed using anti-oxidation Kit (FORD), blood lactic acid Kit (LACTIC ACID), blood uric acid Kit (URIC ACID). Results: 1) One hour after exercise, the antioxidant capacity in both A and B obviously increased without exception and the value of group A was obviously higher than B. The blood lactic acid in both groups dramatically declined and the value of group A was obviously lower than B. The blood uric acid rised in both groups and the value of A was obviously lower than B. Conclusions: Pre-supplement of astaxanthin can accelerate the recovery of antioxidant capacity, accelerate the clearance of blood lactate and delay the increase of blood uric acid in the body within 1 hour after exercise.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise
    AU  - Lijun Wu
    AU  - Zhuo Sun
    AU  - Jing Zhao
    AU  - Xinming Guo
    AU  - Jie Wang
    Y1  - 2019/10/09
    PY  - 2019
    N1  - https://doi.org/10.11648/j.abb.20190704.11
    DO  - 10.11648/j.abb.20190704.11
    T2  - Advances in Bioscience and Bioengineering
    JF  - Advances in Bioscience and Bioengineering
    JO  - Advances in Bioscience and Bioengineering
    SP  - 60
    EP  - 63
    PB  - Science Publishing Group
    SN  - 2330-4162
    UR  - https://doi.org/10.11648/j.abb.20190704.11
    AB  - To study the effects of astaxanthin supplementation on serum antioxidant capacity, blood lactic acid and blood uric acid metabolism of human body in the 1h recovery period after acute high-intensity exercise. Sixteen male students grade 2016 from Physical Education Institution (age: 19.13±2.52, height: 179±4.21cm and weight 68.23±7.81kg) were randomly divided into two groups: group A (experimental) and B (control). Group A was given astaxanthin for 28 days at a moderate dose (12 mg/d) and placebo for 28 days at group B. 4 weeks later, all subjects underwent exercise on power bike. The antioxidant capacity and blood uric acid and the content of blood lactic acid was assayed using anti-oxidation Kit (FORD), blood lactic acid Kit (LACTIC ACID), blood uric acid Kit (URIC ACID). Results: 1) One hour after exercise, the antioxidant capacity in both A and B obviously increased without exception and the value of group A was obviously higher than B. The blood lactic acid in both groups dramatically declined and the value of group A was obviously lower than B. The blood uric acid rised in both groups and the value of A was obviously lower than B. Conclusions: Pre-supplement of astaxanthin can accelerate the recovery of antioxidant capacity, accelerate the clearance of blood lactate and delay the increase of blood uric acid in the body within 1 hour after exercise.
    VL  - 7
    IS  - 4
    ER  - 

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Author Information
  • Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China

  • Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China

  • Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China

  • Department of Physical Education, Taiyuan Normal College, Taiyuan, China

  • Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China

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