Brucellamelitensis is the main causative agent of caprine and ovine brucellosis. Sporadic cases caused by B. abortus have been observed, but cases of natural infection are rare in sheep and goats. Brucellosis is an infectious disease of many domestic and wild animals. Brucellosis is a major cause of direct economic losses resulting from clinical disease, abortion, neonatal losses, reduced fertility, decreased milk production, emergency slaughtering of the infected animals and treatment costs. It also plays a significant role as a barrier for international trade of live animals by being used as an impediment to free animal movement and export. Economic losses in small ruminants stem from breeding inefficiency, loss of lambs and kids, reduced wool, meat and milk production. Clinically, the disease is characterized by one or more of the following signs: abortion, retained placenta, orchitis, epididymitis and, rarely, arthritis, with excretion of the organisms in uterine discharges and in milk. Diagnosis depends on the isolation of Brucella from abortion material, udder secretions or from tissues removed at post-mortem. Presumptive diagnosis of Brucella infection can be made by assessing specific cell-mediated or serological responses to Brucella antigens. Brucellamelitensis is highly pathogenic for humans, causing Malta fever, one of the most serious zoonoses in the world. Identification of the agent Presumptive evidence of Brucella is provided by the demonstration, by modified acid-fast staining of organisms typical of Brucella in abortion material or vaginal discharge, especially if supported by serological tests. The polymerase chain reaction (PCR) methods provide additional means of detection.
Published in | American Journal of Zoology (Volume 3, Issue 1) |
DOI | 10.11648/j.ajz.20200301.14 |
Page(s) | 17-25 |
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Abortion, Brucellosis, Diagnosis, Jimma, Small Ruminant, Zoonosis
[1] | Alemu, Y. (1995): Small ruminants production in Ethiopia. Worl. Sma. Rumin. Ani. Sci. J., 51: 197–201. |
[2] | Glenn J. Songer and Karen W. Post, 2005. Veterinary Microbiology: Bacterial and Fungal agents of animal diseases; p-200-203. |
[3] | Quinn P. J., M. E. Carter, B. K. Markey and G. R. Carter, (1994). Clinical Veterinary Microbiology; p-261. |
[4] | Grimont F, Verger JM, Cornelis P, et al. Molecular typing of Brucella with cloned DNA probes. Res Microbiol. 1992; 143: 55–65. |
[5] | Marin C. M., Moreno E., Moriyon I., Dazi R. & Blasco J. M. (1999) Performance of competitive and indirect enzyme-linked immunosorbent assays, gel immunoprecipitation with native hapten polysaccharide, and standard serological tests in diagnosis sheep brucellosis. Clin. Diagn. Lab. Immunol., 6, 269–272. |
[6] | Alton G. G., Jones L. M., Angus, R. D. & Verger J. M. (1988). Techniques for the Brucellosis Laboratory. INRA, Paris, France., Macmillan a. (1990). Conventional serological tests. In: Animal Brucellosis, Nielsen K. H. & Duncan J. R., eds. CRC Press, Boca Raton, Florida, USA, 153–197). |
[7] | Dwight C. Hirsh and Yaun Chung Zee, (1999). Veterinary Microbiology; pp-197, and 201. Emmerzaal A, de Wit JJ, Dijkstra T, Bakker D, van Zijderveld FG. The Dutch Brucellaabortus monitoring programme for cattle: the impact of false-positive serological reactions and comparison of serological tests. Vet Q. 2002; 24: 40–6. |
[8] | Pan American Health Organization (PAHO) 2001, Zoonoses and communicable diseases common to man and animals. 3rd Edition; V-1; Washington D. C., USA. P 53-55. |
[9] | GrilloMJ., Barberan M., Blasco JM. (1997): Transmission of Brucellamelitensisfrom sheep to lambs. Vet Rec; 140: 602–5. |
[10] | Alton G. G., Jones L. M., Angus R. D., Verger J. M. Techniques for the brucellosis laboratory Iran, Paris. 1988, p. 190. |
[11] | Robles C. A, Uzal F. A., and Olaechea F. V. (1998): Epidemiological observations in a Corriedale flock affected by B. ovis. Vet. Res. Commun., 22: 435-43. |
[12] | Buchanan TM, Hendricks SL, Patton CM, Feldman RA. Brucellosis in the United States, 1960–1972: an abattoir-associated disease. Part III. Epidemiology and evidence for acquired immunity. Medicine (Baltimore). 1974; 53: 427–439. |
[13] | Boschiroli ML, Ouahrani-Bettache S, Foulongne V, et al. Type IV secretion and Brucellavirulence. Vet Microbiol. 2002; 90: 341–348. |
[14] | Young EJ, Borchert M, Kretzer FL, Musher DM. Phagocytosis and killing of Brucellaby human polymorphonuclear leukocytes. J Infect Dis. 1985; 151: 682–690), (Corbeil LB, Blau K, Inzana TJ, et al. Killing of Brucellaabortusby bovine serum. Infect Immun. 1988; 56: 3251–3261. |
[15] | Anderson TD, Cheville NF, Meador VP. Pathogenesis of placentitis in the goat inoculated with Brucellaabortus. II. Ultrastructural studies. Vet Pathol. 1986; 23: 227–239. |
[16] | Anderson TD, Cheville NF. Ultrastructural morphometric analysis of Brucellaabortus-infected trophoblasts in experimental placentitis: bacterial replication occurs in rough endoplasmic reticulum. Am J Pathol. 1987; 124: 226–237. |
[17] | Fensterbank R. (1987): Some aspects of experimentalbovine brucellosis. Ann. Rech. Vet. 18: 421- 428. |
[18] | Greiner M, Verloo D, de Massis F. Meta-analytical equivalence studies on diagnostic tests for bovine brucellosis allowing assessment of a test against a group of comparative tests. Prev Vet Med. 2009; 92: 373–81. doi: 10.1016/j.prevetmed.2009.07.014. |
[19] | OIE Terrestrial Manual 2009 – Ovine epididymitis (Brucellaovis). http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/ 2.07.09_ovine_epid.pdf.Acessoem 11 de fev. 2012. 2009b. |
[20] | Bercovich, Z., Goler, L., Baysal, T., SchreuderBec, Zijderveld and Fgvan, 1998. Evaluation of the current used diagnostic procedures for detection of Brucellamelitensis in sheep. Small Ruminant Research, 31: 1-6; 27. |
[21] | Corbel M. J. (2006): Brucellosis in humans and animals. The World Health Organization, in Collaboration with the Food and Agriculture Organization of the United Nations and the World Organization for Animal Health Geneva: WHO Press. |
[22] | World Health Organization (2006): The control of neglected zoonotic diseases: a route to poverty alleviation: report of a joint WHO/DFID-AHP meeting, 20 and 21 September 2005. Geneva: WHO, with the participation of FAO and OIE. |
[23] | Food and Agriculture Organization of the United Nations (2010): B. melitensis in Eurasia and the Middle East. FAO Animal Production and Health Proceedings. |
[24] | Ashenafi F., Teshale S., Ejeta G., Fikru R., and Laikemariam Y. (2007): Distribution of brucellosis among small ruminants in the Pastoral region of Afar, Eastern E thiopia. Sci. and Tech. Rev. World Organ. Ani. Health, 26: 731–739. |
[25] | Teshale T., Tadele T., Getachew T., Belay B., and Birhanu H. (2013): Sero-prevalence and risk factors study of brucellosis in small ruminants in Southern Zone of Tigray Region, Northern Ethiopia Trop. Anim. Health. Prod45: 1809-1815. |
[26] | Nicoletti P. (1993): The Eradication of Brucellosis in Ann. Saudi. Med. J, 14: 4: 288-292. |
[27] | Kolar, J., 1984. Diagnosis and Control of Brucellosis in Small Ruminants. Preventive Veterinary Medicine 2: 215-225. |
[28] | World Health Organization (1998): Human and Animal Brucellosis. Report of a WHO workshop. Damascus, Syrian Arab Republic, Pp. 4-5. |
APA Style
Wogayehu Seria, Yosefdeneke Diriba Tadese, Eshetu Shumi. (2020). A Review on Brucellosis in Small Ruminants. American Journal of Zoology, 3(1), 17-25. https://doi.org/10.11648/j.ajz.20200301.14
ACS Style
Wogayehu Seria; Yosefdeneke Diriba Tadese; Eshetu Shumi. A Review on Brucellosis in Small Ruminants. Am. J. Zool. 2020, 3(1), 17-25. doi: 10.11648/j.ajz.20200301.14
@article{10.11648/j.ajz.20200301.14, author = {Wogayehu Seria and Yosefdeneke Diriba Tadese and Eshetu Shumi}, title = {A Review on Brucellosis in Small Ruminants}, journal = {American Journal of Zoology}, volume = {3}, number = {1}, pages = {17-25}, doi = {10.11648/j.ajz.20200301.14}, url = {https://doi.org/10.11648/j.ajz.20200301.14}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajz.20200301.14}, abstract = {Brucellamelitensis is the main causative agent of caprine and ovine brucellosis. Sporadic cases caused by B. abortus have been observed, but cases of natural infection are rare in sheep and goats. Brucellosis is an infectious disease of many domestic and wild animals. Brucellosis is a major cause of direct economic losses resulting from clinical disease, abortion, neonatal losses, reduced fertility, decreased milk production, emergency slaughtering of the infected animals and treatment costs. It also plays a significant role as a barrier for international trade of live animals by being used as an impediment to free animal movement and export. Economic losses in small ruminants stem from breeding inefficiency, loss of lambs and kids, reduced wool, meat and milk production. Clinically, the disease is characterized by one or more of the following signs: abortion, retained placenta, orchitis, epididymitis and, rarely, arthritis, with excretion of the organisms in uterine discharges and in milk. Diagnosis depends on the isolation of Brucella from abortion material, udder secretions or from tissues removed at post-mortem. Presumptive diagnosis of Brucella infection can be made by assessing specific cell-mediated or serological responses to Brucella antigens. Brucellamelitensis is highly pathogenic for humans, causing Malta fever, one of the most serious zoonoses in the world. Identification of the agent Presumptive evidence of Brucella is provided by the demonstration, by modified acid-fast staining of organisms typical of Brucella in abortion material or vaginal discharge, especially if supported by serological tests. The polymerase chain reaction (PCR) methods provide additional means of detection.}, year = {2020} }
TY - JOUR T1 - A Review on Brucellosis in Small Ruminants AU - Wogayehu Seria AU - Yosefdeneke Diriba Tadese AU - Eshetu Shumi Y1 - 2020/02/28 PY - 2020 N1 - https://doi.org/10.11648/j.ajz.20200301.14 DO - 10.11648/j.ajz.20200301.14 T2 - American Journal of Zoology JF - American Journal of Zoology JO - American Journal of Zoology SP - 17 EP - 25 PB - Science Publishing Group SN - 2994-7413 UR - https://doi.org/10.11648/j.ajz.20200301.14 AB - Brucellamelitensis is the main causative agent of caprine and ovine brucellosis. Sporadic cases caused by B. abortus have been observed, but cases of natural infection are rare in sheep and goats. Brucellosis is an infectious disease of many domestic and wild animals. Brucellosis is a major cause of direct economic losses resulting from clinical disease, abortion, neonatal losses, reduced fertility, decreased milk production, emergency slaughtering of the infected animals and treatment costs. It also plays a significant role as a barrier for international trade of live animals by being used as an impediment to free animal movement and export. Economic losses in small ruminants stem from breeding inefficiency, loss of lambs and kids, reduced wool, meat and milk production. Clinically, the disease is characterized by one or more of the following signs: abortion, retained placenta, orchitis, epididymitis and, rarely, arthritis, with excretion of the organisms in uterine discharges and in milk. Diagnosis depends on the isolation of Brucella from abortion material, udder secretions or from tissues removed at post-mortem. Presumptive diagnosis of Brucella infection can be made by assessing specific cell-mediated or serological responses to Brucella antigens. Brucellamelitensis is highly pathogenic for humans, causing Malta fever, one of the most serious zoonoses in the world. Identification of the agent Presumptive evidence of Brucella is provided by the demonstration, by modified acid-fast staining of organisms typical of Brucella in abortion material or vaginal discharge, especially if supported by serological tests. The polymerase chain reaction (PCR) methods provide additional means of detection. VL - 3 IS - 1 ER -