@article{10.11648/j.bio.20210905.11,
  author = {Sindhu Baloch and Adnan Yousaf and Saba Shaheen and Samia Shaheen and Inayatullah Sarki and Abdullah Babar and Asfa Sakhawat and Mamoona Arshad and Khalil-ur-Rehman and Shah Jahan Musakhail and Allah Bachaya and Faiza Habib},
  title = {Study on the Prevalence of Peste Des Petits Virus Antibodies in Caprine and Ovine Through the Contrast of Serological Assessments in Sindh, Pakistan},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {9},
  number = {5},
  pages = {131-135},
  doi = {10.11648/j.bio.20210905.11},
  url = {https://doi.org/10.11648/j.bio.20210905.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20210905.11},
  abstract = {Peste-des-petits-ruminants (PPR) is a notifiable, contagious and economically important transboundary viral disease of small ruminant causing high morbidity and mortality. It belongs to negative-sense, single-stranded RNA paramyxovirus of genus Morbillivirus. PPR occurs in populations of immunologically naive sheep and goats, illness and death can be high as >90%. It results in a high rate of morbidity and a moderate rate of mortality. After the eradication of the rinderpest virus, which is closely relate to PPRV of small ruminants contaminated with SRMV are diagnosed having pyrexia, oculo-nasal discharges, necrotizing and erosive stomatitis, gastroenteritis, diarrhea and broncho pneumonia, whereas, gross pathology, histological findings along with laboratory confirmation of specific virus antigen, antibodies, genome in the clinical samples through a variety of serological and molecular diagnostic tests can be useful. The goal of this study was to use competitive-ELISA to determine the prevalence of PPR in small ruminants in Sindh province. A total of n=5700 blood samples were taken from sheep (800) and goats (4900) in 06 Sindh districts. In the small ruminant population, the overall prevalence was found to be 27.84%. Goats were found to have a higher prevalence (28.29%) than sheep (25.13%). Prevalence in goats varied by age category, with 27.84%, 24.88%, and 34.29% in three age groups, i.e less than 1 years, 1-2 years, and more than 2 years and in sheep’s 18.75%, 23.95%, and 36.11% respectively. Females had a greater prevalence rate than males. The prevalence of PPR varies across the province's several agro-ecological zones. Tharparkar district had the greatest% age (35.38%), while Hyderabad district had the lowest (18.27%). Because PPR is endemic in Sindh, there is a pressing need for infection prevention through vaccination. PPR can be controlled through mass vaccination program. In the future, the preparation of a marker vaccine with a robust companion test may assist in serosurveillance for the detection of infection in vaccinated animals to control the disease.},
 year = {2021}
}

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TY  - JOUR
T1  - Study on the Prevalence of Peste Des Petits Virus Antibodies in Caprine and Ovine Through the Contrast of Serological Assessments in Sindh, Pakistan
AU  - Sindhu Baloch
AU  - Adnan Yousaf
AU  - Saba Shaheen
AU  - Samia Shaheen
AU  - Inayatullah Sarki
AU  - Abdullah Babar
AU  - Asfa Sakhawat
AU  - Mamoona Arshad
AU  - Khalil-ur-Rehman
AU  - Shah Jahan Musakhail
AU  - Allah Bachaya
AU  - Faiza Habib
Y1  - 2021/09/23
PY  - 2021
N1  - https://doi.org/10.11648/j.bio.20210905.11
DO  - 10.11648/j.bio.20210905.11
T2  - American Journal of Bioscience and Bioengineering
JF  - American Journal of Bioscience and Bioengineering
JO  - American Journal of Bioscience and Bioengineering
SP  - 131
EP  - 135
PB  - Science Publishing Group
SN  - 2328-5893
UR  - https://doi.org/10.11648/j.bio.20210905.11
AB  - Peste-des-petits-ruminants (PPR) is a notifiable, contagious and economically important transboundary viral disease of small ruminant causing high morbidity and mortality. It belongs to negative-sense, single-stranded RNA paramyxovirus of genus Morbillivirus. PPR occurs in populations of immunologically naive sheep and goats, illness and death can be high as >90%. It results in a high rate of morbidity and a moderate rate of mortality. After the eradication of the rinderpest virus, which is closely relate to PPRV of small ruminants contaminated with SRMV are diagnosed having pyrexia, oculo-nasal discharges, necrotizing and erosive stomatitis, gastroenteritis, diarrhea and broncho pneumonia, whereas, gross pathology, histological findings along with laboratory confirmation of specific virus antigen, antibodies, genome in the clinical samples through a variety of serological and molecular diagnostic tests can be useful. The goal of this study was to use competitive-ELISA to determine the prevalence of PPR in small ruminants in Sindh province. A total of n=5700 blood samples were taken from sheep (800) and goats (4900) in 06 Sindh districts. In the small ruminant population, the overall prevalence was found to be 27.84%. Goats were found to have a higher prevalence (28.29%) than sheep (25.13%). Prevalence in goats varied by age category, with 27.84%, 24.88%, and 34.29% in three age groups, i.e less than 1 years, 1-2 years, and more than 2 years and in sheep’s 18.75%, 23.95%, and 36.11% respectively. Females had a greater prevalence rate than males. The prevalence of PPR varies across the province's several agro-ecological zones. Tharparkar district had the greatest% age (35.38%), while Hyderabad district had the lowest (18.27%). Because PPR is endemic in Sindh, there is a pressing need for infection prevention through vaccination. PPR can be controlled through mass vaccination program. In the future, the preparation of a marker vaccine with a robust companion test may assist in serosurveillance for the detection of infection in vaccinated animals to control the disease.
VL  - 9
IS  - 5
ER  - 

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