Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones

Rufayda Omar Musa; Omer Fadl Idris

doi:doi:10.11648/j.bs.20170301.12

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Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones

Rufayda Omar Musa, Omer Fadl Idris

Published in Biomedical Sciences (Volume 3, Issue 1)

Received: 6 December 2016 Accepted: 14 January 2017 Published: 9 February 2017

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Abstract

Some elements may take part in the initiation of stone crystallization or inhibitor in urine, in this study; we estimated some of trace elements in patients and control groups to correlate between the distributions of trace elements in the serum with kidney stone formation in Sudanese's patient. This is descriptive cross-sectional study correlated during 1st May to 30ty September 2014 and was conducted in Khartoum State hospitals. Sixty blood samples were collected from the patients at Urology unit along with forty blood samples as a control, the mean ± SD of the age in patients were 41.75 ± 2.03 and for the control were 42.95±1.67, this study included both gender. Biochemical analysis of serum samples was carried out for the patients and the control group to estimate some of the trace elements (Zn, Cu, Mg and Mn) concentrations. It was found that there is a statistical significant difference in Zn and Mn concentration between the two groups with P value in Zn (0.003) and in Mn (0.000), but not in Mg and Cu concentration, P value in Mg (0.074) and in Cu (0.273). Our study suggested that increase of Zn and decrease of Mn associated with increased risk factor of kidney stone disease.

Published in	Biomedical Sciences (Volume 3, Issue 1)
DOI	10.11648/j.bs.20170301.12
Page(s)	6-9
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Trace Element, Kidney Stones, Biochemical Analysis, Statistical Analysis

References

[1]	Litwin MD and Saigal, CS. (2012). Urologic Diseases in America. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. Washington, D. C.: Government Printing Office; NIH publication 12–7865.
[2]	John S. Rodman, R. Ernest Sosa, Cynthia Seidman, Rory Jones. (2007). No More Kidney Stone, United States, Hoboken, New Jersey, 2007, page 20-30.
[3]	Doddametikurke Ramegowda Basavaraj, Chandra Shekhar Biyani, Anthony J. Browning, Jon J. Cartledge. (2007). The Role of Urinary Kidney Stone Inhibitors and Promoters in the Pathogenesis of Calcium Containing Renal Stones. Published by Elsevier B. V. on behalf of European Association of Urology and European Board of Urology. www.sciencedirect.com.
[4]	Vivek K. Singh and Pradeep K. Rai. (2014). Kidney stone analysis techniques and the role of major and trace elements on their pathogenesis: a review. Biophysical Reviews.31 Jul.
[5]	Marcin Słojewski. (2011). Major and trace elements in lithogenesismCent European J Urol; 64 (2): 58-61.
[6]	Giannossi ML, Summa V, Mongelli G. (2013). Trace element investigations in urinary stones: a preliminary pilot case in Basilicata (Southern Italy). J Trace Elem Med Biol. 2013 Apr; 27 (2): 91-7. doi: 10.1016/j.jtemb.2012.09.004. Epub 2012 Nov 8.
[7]	Tang J, McFann K, Chonchol M. (2012). Dietary zinc intake and kidney stone formation: evaluation of NHANES III. Am J Nephrol.; 36 (6): 549-53. doi: 10.1159/000345550. Epub 2012 Dec 4.
[8]	Atakan IH, Kaplan M and Seren G. (2007). Serum, urinary and stone zinc, iron, magnesium and copper levels in idiopathic calcium oxalate stone patients. IntUrolNephrol; 39: 351-356.
[9]	Komleh K, Hada P, Pendse AK, Singh PP. (1990). Zinc, copper and manganese in serum, urine and stones. IntUrolNephrol. 1990; 22: 113–118.
[10]	Turgut M, Unal I, Berber A. (2008). The concentration of Zn, Mg and Mn in calcium oxalate monohydrate stones appears to interfere with their fragility. Urol Res; 36: 31–38.
[11]	Schmiedl A and Schwille PO. (1996). Magnesium status in idiopathic calcium urolithiasis an orientational study in younger males. Eur J ClinChemClinBiochem.; 34: 393–400.
[12]	Hofbauer J., Steffan I., Höbarth K. (1991). Trace elements and urinary stone formation: new aspects of the pathological mechanism of urinary stone formation. J Urol; 145: 93–96.

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APA Style

Rufayda Omar Musa, Omer Fadl Idris. (2017). Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones. Biomedical Sciences, 3(1), 6-9. https://doi.org/10.11648/j.bs.20170301.12

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ACS Style

Rufayda Omar Musa; Omer Fadl Idris. Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones. Biomed. Sci. 2017, 3(1), 6-9. doi: 10.11648/j.bs.20170301.12

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AMA Style

Rufayda Omar Musa, Omer Fadl Idris. Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones. Biomed Sci. 2017;3(1):6-9. doi: 10.11648/j.bs.20170301.12

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@article{10.11648/j.bs.20170301.12,
  author = {Rufayda Omar Musa and Omer Fadl Idris},
  title = {Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones},
  journal = {Biomedical Sciences},
  volume = {3},
  number = {1},
  pages = {6-9},
  doi = {10.11648/j.bs.20170301.12},
  url = {https://doi.org/10.11648/j.bs.20170301.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20170301.12},
  abstract = {Some elements may take part in the initiation of stone crystallization or inhibitor in urine, in this study; we estimated some of trace elements in patients and control groups to correlate between the distributions of trace elements in the serum with kidney stone formation in Sudanese's patient. This is descriptive cross-sectional study correlated during 1st May to 30ty September 2014 and was conducted in Khartoum State hospitals. Sixty blood samples were collected from the patients at Urology unit along with forty blood samples as a control, the mean ± SD of the age in patients were 41.75 ± 2.03 and for the control were 42.95±1.67, this study included both gender. Biochemical analysis of serum samples was carried out for the patients and the control group to estimate some of the trace elements (Zn, Cu, Mg and Mn) concentrations. It was found that there is a statistical significant difference in Zn and Mn concentration between the two groups with P value in Zn (0.003) and in Mn (0.000), but not in Mg and Cu concentration, P value in Mg (0.074) and in Cu (0.273). Our study suggested that increase of Zn and decrease of Mn associated with increased risk factor of kidney stone disease.},
 year = {2017}
}

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TY  - JOUR
T1  - Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones
AU  - Rufayda Omar Musa
AU  - Omer Fadl Idris
Y1  - 2017/02/09
PY  - 2017
N1  - https://doi.org/10.11648/j.bs.20170301.12
DO  - 10.11648/j.bs.20170301.12
T2  - Biomedical Sciences
JF  - Biomedical Sciences
JO  - Biomedical Sciences
SP  - 6
EP  - 9
PB  - Science Publishing Group
SN  - 2575-3932
UR  - https://doi.org/10.11648/j.bs.20170301.12
AB  - Some elements may take part in the initiation of stone crystallization or inhibitor in urine, in this study; we estimated some of trace elements in patients and control groups to correlate between the distributions of trace elements in the serum with kidney stone formation in Sudanese's patient. This is descriptive cross-sectional study correlated during 1st May to 30ty September 2014 and was conducted in Khartoum State hospitals. Sixty blood samples were collected from the patients at Urology unit along with forty blood samples as a control, the mean ± SD of the age in patients were 41.75 ± 2.03 and for the control were 42.95±1.67, this study included both gender. Biochemical analysis of serum samples was carried out for the patients and the control group to estimate some of the trace elements (Zn, Cu, Mg and Mn) concentrations. It was found that there is a statistical significant difference in Zn and Mn concentration between the two groups with P value in Zn (0.003) and in Mn (0.000), but not in Mg and Cu concentration, P value in Mg (0.074) and in Cu (0.273). Our study suggested that increase of Zn and decrease of Mn associated with increased risk factor of kidney stone disease.
VL  - 3
IS  - 1
ER  -

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Author Information

Rufayda Omar Musa

Department of Biochemistry and Molecular Biology, Collage of Science and Technology, Al-Neelain University, Khartoum, Sudan
Omer Fadl Idris

Department of Biochemistry and Molecular Biology, Collage of Science and Technology, Al-Neelain University, Khartoum, Sudan

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APA Style

Rufayda Omar Musa, Omer Fadl Idris. (2017). Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones. Biomedical Sciences, 3(1), 6-9. https://doi.org/10.11648/j.bs.20170301.12

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ACS Style

Rufayda Omar Musa; Omer Fadl Idris. Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones. Biomed. Sci. 2017, 3(1), 6-9. doi: 10.11648/j.bs.20170301.12

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AMA Style

Rufayda Omar Musa, Omer Fadl Idris. Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones. Biomed Sci. 2017;3(1):6-9. doi: 10.11648/j.bs.20170301.12

Copy | Download

@article{10.11648/j.bs.20170301.12,
  author = {Rufayda Omar Musa and Omer Fadl Idris},
  title = {Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones},
  journal = {Biomedical Sciences},
  volume = {3},
  number = {1},
  pages = {6-9},
  doi = {10.11648/j.bs.20170301.12},
  url = {https://doi.org/10.11648/j.bs.20170301.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20170301.12},
  abstract = {Some elements may take part in the initiation of stone crystallization or inhibitor in urine, in this study; we estimated some of trace elements in patients and control groups to correlate between the distributions of trace elements in the serum with kidney stone formation in Sudanese's patient. This is descriptive cross-sectional study correlated during 1st May to 30ty September 2014 and was conducted in Khartoum State hospitals. Sixty blood samples were collected from the patients at Urology unit along with forty blood samples as a control, the mean ± SD of the age in patients were 41.75 ± 2.03 and for the control were 42.95±1.67, this study included both gender. Biochemical analysis of serum samples was carried out for the patients and the control group to estimate some of the trace elements (Zn, Cu, Mg and Mn) concentrations. It was found that there is a statistical significant difference in Zn and Mn concentration between the two groups with P value in Zn (0.003) and in Mn (0.000), but not in Mg and Cu concentration, P value in Mg (0.074) and in Cu (0.273). Our study suggested that increase of Zn and decrease of Mn associated with increased risk factor of kidney stone disease.},
 year = {2017}
}

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TY  - JOUR
T1  - Evaluation of Some Trace Elements (Zn, Cu, Mg and Mn), Among Patients with Kidney Stones
AU  - Rufayda Omar Musa
AU  - Omer Fadl Idris
Y1  - 2017/02/09
PY  - 2017
N1  - https://doi.org/10.11648/j.bs.20170301.12
DO  - 10.11648/j.bs.20170301.12
T2  - Biomedical Sciences
JF  - Biomedical Sciences
JO  - Biomedical Sciences
SP  - 6
EP  - 9
PB  - Science Publishing Group
SN  - 2575-3932
UR  - https://doi.org/10.11648/j.bs.20170301.12
AB  - Some elements may take part in the initiation of stone crystallization or inhibitor in urine, in this study; we estimated some of trace elements in patients and control groups to correlate between the distributions of trace elements in the serum with kidney stone formation in Sudanese's patient. This is descriptive cross-sectional study correlated during 1st May to 30ty September 2014 and was conducted in Khartoum State hospitals. Sixty blood samples were collected from the patients at Urology unit along with forty blood samples as a control, the mean ± SD of the age in patients were 41.75 ± 2.03 and for the control were 42.95±1.67, this study included both gender. Biochemical analysis of serum samples was carried out for the patients and the control group to estimate some of the trace elements (Zn, Cu, Mg and Mn) concentrations. It was found that there is a statistical significant difference in Zn and Mn concentration between the two groups with P value in Zn (0.003) and in Mn (0.000), but not in Mg and Cu concentration, P value in Mg (0.074) and in Cu (0.273). Our study suggested that increase of Zn and decrease of Mn associated with increased risk factor of kidney stone disease.
VL  - 3
IS  - 1
ER  -

Copy | Download