Biomedical and Micro-Robots: An Overview of Recent Developments

Alireza Shamsabadi Masoudi; Mohammad Sadegh Hassanli; Zahra Taavili; Yasaman Sadeghizade

doi:doi:10.11648/j.cbe.20170202.13

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Biomedical and Micro-Robots: An Overview of Recent Developments

Alireza Shamsabadi Masoudi, Mohammad Sadegh Hassanli, Zahra Taavili, Yasaman Sadeghizade

Published in Chemical and Biomolecular Engineering (Volume 2, Issue 2)

Received: 7 January 2017 Accepted: 29 January 2017 Published: 4 March 2017

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Abstract

This paper aims to provide an overview of recent challenges in the development of micro-robots for future biomedical applications. This paper first considers a comprehensive survey of the state-of-the-art in medical micro-robots. Consequently, it investigates the critical aspects and emerging ideas associated with designing of such medical micro-robots in order to navigate in viscous environments and inspire future research for healthcare applications. Potential biomedical micro-robots are used for a wide variety of applications into different organs of the patient's body, such as clearing heart occlusion, treatment of Nephrolithotomy, minimally invasive surgery, micromanipulative, released into the bloodstream and targeted drug delivery. Challenges and emerging concepts include functionality, powering, robot localization, communication and safety have been proposed, thereby leading to enable an extensive range of medical operations locomotion features, obtain and process information, being able to operate within specific constraints. This review provides details insight of medical micro-robot developments and the existing solutions for challenges and emerging concepts paving the way for designing such a medical micro-robot for operation inside, fast recovery and increased quality of life of patients.

Published in	Chemical and Biomolecular Engineering (Volume 2, Issue 2)
DOI	10.11648/j.cbe.20170202.13
Page(s)	90-95
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Biomedical Robot, Micro-Robots, Minimally Invasive Surgery, Treatment of Nephrolithotomy

References

[1]	Zheng L, Chen LG, Huang HB, Li XP, Zhang LL. An overview of magnetic micro-robot systems for biomedical applications. Microsystem Technologies. 2016 Oct 1; 22 (10): 2371-87.
[2]	Zhang X, Khamesee MB. Magnetically Driven Microrobotics for Micromanipulation and Biomedical Applications. In Advanced Mechatronics and MEMS Devices II 2017 (pp. 613-635). Springer International Publishing.
[3]	Moghadam NN, Farhadi H, Bengtsson M. An energy efficient communication technique for medical implants/micro robots. In Medical Information and Communication Technology (ISMICT), 2016 10th International Symposium on 2016 Mar 20 (pp. 1-5). IEEE.
[4]	M. Sitti, ‘‘Miniature devices: Voyage of the micro-robots,’’ Nature, vol. 458, pp. 1121–1122, Apr. 2009.
[5]	B. J. Nelson, I. K. Kaliakatsos, and J. J. Abbott, ‘‘Micro-robots for minimally invasive medicine,’’ Annu. Rev. Biomed. Eng., vol. 12, pp. 55–85, Aug. 2010.
[6]	Sitti, Metin, et al. "Biomedical applications of untethered mobile milli/micro-robots." Proceedings of the IEEE 103.2 (2015): 205-224.
[7]	R. S. Fearing et al., ‘‘Wing transmission for a micromechanical flying insect,’’ in Proc. 2000 IEEE Int. Conf. Robot. Automation (ICRA), San Francisco, CA, USA, 2000, pp. 1509–1516.
[8]	S. Hollar, A. Flynn, C. Bellew, and K. Pister, ‘‘Solar powered 10 mg silicon robot,’’ in Proc. 2003 IEEE Sixteenth Annu. Int. Conf. Micro Electro Mechanical Systems (MEMS), Kyoto, Japan, 2003, pp. 706–711.
[9]	A. M. Hoover, E. Steltz, and R. S. Fearing, ‘‘RoACH: An autonomous 2.4 g crawling hexapod robot,’’ in Proc. IEEE/RSJ 2008 Int. Conf. Intell. Robots Syst. (IROS), Nice, France, 2008, pp. 26–33.
[10]	K. Y. Ma, P. Chirarattananon, S. B. Fuller, and R. J. Wood, ‘‘Controlled flight of a biologically inspired, insect-scale robot,’’Science, vol. 340, pp. 603–607, May 3, 2013.
[11]	J. Edd, S. Payen, B. Rubinsky, M. L. Stoller, and M. Sitti, ‘‘Biomimetic propulsion for a swimming surgical micro-robot,’’ in Proc. 2003 IEEE/RSJ Int. Conf. Intelligent Robots Syst. (IROS), Las Vegas, NV, USA, 2003, pp. 2583–2588.
[12]	O. J. Sul, M. R. Falvo, R. M. Taylor, S. Washburn, and R. Superfine, ‘‘thermally actuated untethered impact-driven locomotive microdevices,’’ Appl. Phys. Lett., vol. 89, p. 203512, 2006.
[13]	R. Dreyfus et al., ‘‘Microscopic artificial swimmers,’’ Nature, vol. 437, pp. 862–865, Oct. 2005.
[14]	N. Darnton, L. Turner, K. Breuer, and H. C. Berg, ‘‘Moving fluid with bacterial carpets,’’ Biophys. J., vol. 86, pp. 1863–1870, Mar. 2004.
[15]	B. Behkam and M. Sitti, ‘‘Bacterial flagella-based propulsion and on/off motion control of microscale objects,’’ Appl. Phys. Lett., vol. 90, p. 023902, 2007.
[16]	Nguyen PB, Park JO, Park S, Ko SY. Medical micro-robot navigation using image processing-blood vessel extraction and X-ray calibration. InBiomedical Robotics and Biomechatronics (BioRob), 2016 6th IEEE International Conference on 2016 Jun 26 (pp. 365-370). IEEE.
[17]	K. B. Yesin, ‘‘Modeling and control of untethered biomicro-robots in a fluidic environment using electromagnetic fields,’’ Int. J. Robot. Res., vol. 25, pp. 527–536, 2006.
[18]	B. R. Donald, C. G. Levey, C. D. McGray, I. Paprotny, and D. Rus, ‘‘An untethered, electrostatic, globally controllable MEMS micro-robot,’’ J. Micromech. Microeng., vol. 15, pp. 1–15, 2006.
[19]	A. Shourangiz Haghighi, I. Zare. Mohammad Ahmadi Balootaki, Mohammad Orak, Omid Zare. Modeling of Bio-inspired Thunnus Albacares and Inchworm-gammarus with Micro Actuators in One Structure. International Journal of Science and Qualitative Analysis. Vol. 1, No. 3, 2015, pp. 54-63.
[20]	Dario, P., Valleggi, R., Carrozza, M. C., Montesi, M. C., Cocco, M.: J. Micromech. Microeng. 141 (1992)
[21]	Ebefors, T., Stemme, G.: In: Gad-El-Hak, M. (ed.) The MEMS Handbook, p. 281. CRC Press, University of Notre Dame (2002)
[22]	Valdastri, P., Menciassi, A., and Dario, P. Transmission power requirements for novel ZigBee implants in the gastrointestinal tract. IEEE Trans. Biomed. Eng., 2008, 55, 1705–1710.
[23]	E. Diller and M. Sitti, ‘‘Three-dimensional programmable assembly by untethered magnetic robotic micro-grippers,’’ Adv. Funct. Mater., vol. 24, pp. 4397–4404, 2014.
[24]	J. Giltinan, E. Diller, C. Mayda, and M. Sitti, ‘‘Three-dimensional robotic manipulation and transport of micro-scale objects by a magnetically driven capillary micro-gripper,’’ in Proc. IEEE Int. Conf. Robot. Automation (ICRA), Hong Kong, 2014, pp. 2077–2082.
[25]	H. Messmann, R. Knuchel, W. Baumler, A. Holstege, and J. Scholmerich,‘‘Endoscopic fluorescence detection of dysplasia in patients with Barrett’s esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization,’’ Gastrointest. Endoscopy, vol. 49, pp. 97–101, Jan. 1999.
[26]	P. Mountney and G. Z. Yang, ‘‘Motion compensated SLAM for image guided surgery,’’ Med. Image Comput. Computat. Assist. Interv., vol. 13, pp. 496–504, 2010.
[27]	H. G. Lee, M. K. Choi, and S. C. Lee, ‘‘Motion analysis for duplicate frame removal in wireless capsule endoscope,’’ Medical Imaging 2011: Image Processing, vol. 7962, 2011.
[28]	S. Yoshizaki, A. Serb, L. Yan, and T. G. Constandinou, ‘‘Octagonal CMOs image sensor with strobed RGB LED illumination for wireless capsule endoscopy,’’ in Proc. 2014 IEEE Int. Symp. Circuits Syst. (ISCAS), Melbourne, Australia, 2014, pp. 1857–1860.
[29]	P. L. Lam and R. Gambari, ‘‘Advanced progress of microencapsulation technologies: In vivo and in vitro models for studying oral and transdermal drug deliveries,’’ J. Control. Release, vol. 178, pp. 25–45, Mar. 2014.
[30]	M. V. Kiryukhin, ‘‘Active drug release systems: Current status, applications and perspectives,’’ Curr. Opin. Pharmacol., vol. 18C, pp. 69–75, Sep. 2014.
[31]	S. Mura, J. Nicolas, and P. Couvreur, ‘‘Stimuli-responsive nanocarriers for drug delivery,’’ Nat. Mater., vol. 12, pp. 991–1003, Nov. 2013.
[32]	D. R. Frutiger, K. Vollmers, B. E. Kratochvil, and B. J. Nelson, ‘‘Small, fast, under control: Wireless resonant magnetic micro-agents,’’ Int. J. Robot. Res., vol. 29, pp. 613–636, Apr. 2011.
[33]	Haghighi, Alireza Shourangiz, Iman Zare, Alireza Fallahi, Reza Jahromi Bosheri, Amin Haghnegahdar, and Hamidreza Naji. "Dynamic modeling of flexible tail for bio-inspired dogfish shark (Squalus acanthias)- inchworm with multifunctional locomotion." In 7th Iranian Conference of Electrical and Electronics Engineering, pp. 126-132. IEEE, 2015.
[34]	T. Y. Huang et al., ‘‘Cooperative manipulation and transport of microobjects using multiple helical microcarriers,’’ RSC Adv., vol. 4, pp. 26771–26771, 2014.
[35]	C. H. Siu, T. J. C. Harris, J. Wang, and E. Wong, ‘‘Regulation of cell-cell adhesion during Dictyostelium development,’’ Seminars in Cell Develop. Biol., vol. 15, pp. 633–641, Dec. 2013.
[36]	W. F. Loomis, ‘‘Cell signaling during development of Dictyostelium,’’ Dev. Biol., vol. 391, pp. 1–16, Jul. 1, 2014.
[37]	G. Shaulsky and R. H. Kessin, ‘‘The cold war of the social amoebae,’’ Current Biology, vol. 17, pp. R684–R692, Aug. 2007.
[38]	S. T. Rutherford and B. L. Bassler, ‘‘Bacterial quorum sensing: Its role in virulence and possibilities for its control,’’ Cold Spring Harbor Perspectives in Medicine, vol. 2, Nov. 1, 2012.
[39]	Yesin KB, Vollmers K, Nelson BJ. 2004. Guidance of magnetic intraocular micro-robots by active defocused tracking. Proc. IEEE/RSJ Int. Conf. Intell. Robots Syst., Sendai, Japan, Sept. 28–Oct. 2, pp. 3309–14.
[40]	Bergeles C, Shamaei K, Abbott JJ, Nelson BJ. 2010. Single-camera focus-based localization of intraocular devices. IEEE Trans. Biomed. Eng. In press.
[41]	Bergeles C, Fagogenis G, Abbott JJ, Nelson BJ. 2009. Tracking intraocular microdevices based on colorspace evaluation and statistical color/shape information. Proc. IEEE Int. Conf. Robot. Autom., Kobe, Japan, May 12–17, pp. 3934–39.
[42]	Menciassi, A., Valdastri, P., Harada, K., Dario, P.: In: Biomedical Robotics and Biomechatronics, 2008. BioRob 2008. 2nd IEEE RAS & EMBS International Conference, p. 238 (2008).
[43]	Montane, E., Bota, S. A., Lopez-Sanchez, J., Miribel-Catala, P., Puig-Vidal, M., Samitier, J.: In: Solid-State Circuits Conference, 2001. ESSCIRC 2001. Proceedings of the 27th European, p. 249 (2001).
[44]	Alireza Shourangiz Haghighi, Amin Haghnegahdar, Reza Jahromi Bosheri, Iman Zare. Micro-embedded Skimmer in Autonomous Underwater Micro-robots. International Journal of Science and Qualitative Analysis. Vol. 1, No. 3, 2015, pp. 43-53.
[45]	Casanova, R., Dieguez, A., Arbat, A., Samitier, J.: J. Low Power Electron. 2, 291 (2010).
[46]	Casanova, R., Dieguez, A., Arbat, A., Alonso, O., Canals, J., Sanuy, A., Samitier, J.: 2015 50th Midwest Symposium on Circuits and Systems, vols 1–3, p. 695 (2015).

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Alireza Shamsabadi Masoudi, Mohammad Sadegh Hassanli, Zahra Taavili, Yasaman Sadeghizade. (2017). Biomedical and Micro-Robots: An Overview of Recent Developments. Chemical and Biomolecular Engineering, 2(2), 90-95. https://doi.org/10.11648/j.cbe.20170202.13

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ACS Style

Alireza Shamsabadi Masoudi; Mohammad Sadegh Hassanli; Zahra Taavili; Yasaman Sadeghizade. Biomedical and Micro-Robots: An Overview of Recent Developments. Chem. Biomol. Eng. 2017, 2(2), 90-95. doi: 10.11648/j.cbe.20170202.13

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AMA Style

Alireza Shamsabadi Masoudi, Mohammad Sadegh Hassanli, Zahra Taavili, Yasaman Sadeghizade. Biomedical and Micro-Robots: An Overview of Recent Developments. Chem Biomol Eng. 2017;2(2):90-95. doi: 10.11648/j.cbe.20170202.13

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@article{10.11648/j.cbe.20170202.13,
  author = {Alireza Shamsabadi Masoudi and Mohammad Sadegh Hassanli and Zahra Taavili and Yasaman Sadeghizade},
  title = {Biomedical and Micro-Robots: An Overview of Recent Developments},
  journal = {Chemical and Biomolecular Engineering},
  volume = {2},
  number = {2},
  pages = {90-95},
  doi = {10.11648/j.cbe.20170202.13},
  url = {https://doi.org/10.11648/j.cbe.20170202.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cbe.20170202.13},
  abstract = {This paper aims to provide an overview of recent challenges in the development of micro-robots for future biomedical applications. This paper first considers a comprehensive survey of the state-of-the-art in medical micro-robots. Consequently, it investigates the critical aspects and emerging ideas associated with designing of such medical micro-robots in order to navigate in viscous environments and inspire future research for healthcare applications. Potential biomedical micro-robots are used for a wide variety of applications into different organs of the patient's body, such as clearing heart occlusion, treatment of Nephrolithotomy, minimally invasive surgery, micromanipulative, released into the bloodstream and targeted drug delivery. Challenges and emerging concepts include functionality, powering, robot localization, communication and safety have been proposed, thereby leading to enable an extensive range of medical operations locomotion features, obtain and process information, being able to operate within specific constraints. This review provides details insight of medical micro-robot developments and the existing solutions for challenges and emerging concepts paving the way for designing such a medical micro-robot for operation inside, fast recovery and increased quality of life of patients.},
 year = {2017}
}

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TY  - JOUR
T1  - Biomedical and Micro-Robots: An Overview of Recent Developments
AU  - Alireza Shamsabadi Masoudi
AU  - Mohammad Sadegh Hassanli
AU  - Zahra Taavili
AU  - Yasaman Sadeghizade
Y1  - 2017/03/04
PY  - 2017
N1  - https://doi.org/10.11648/j.cbe.20170202.13
DO  - 10.11648/j.cbe.20170202.13
T2  - Chemical and Biomolecular Engineering
JF  - Chemical and Biomolecular Engineering
JO  - Chemical and Biomolecular Engineering
SP  - 90
EP  - 95
PB  - Science Publishing Group
SN  - 2578-8884
UR  - https://doi.org/10.11648/j.cbe.20170202.13
AB  - This paper aims to provide an overview of recent challenges in the development of micro-robots for future biomedical applications. This paper first considers a comprehensive survey of the state-of-the-art in medical micro-robots. Consequently, it investigates the critical aspects and emerging ideas associated with designing of such medical micro-robots in order to navigate in viscous environments and inspire future research for healthcare applications. Potential biomedical micro-robots are used for a wide variety of applications into different organs of the patient's body, such as clearing heart occlusion, treatment of Nephrolithotomy, minimally invasive surgery, micromanipulative, released into the bloodstream and targeted drug delivery. Challenges and emerging concepts include functionality, powering, robot localization, communication and safety have been proposed, thereby leading to enable an extensive range of medical operations locomotion features, obtain and process information, being able to operate within specific constraints. This review provides details insight of medical micro-robot developments and the existing solutions for challenges and emerging concepts paving the way for designing such a medical micro-robot for operation inside, fast recovery and increased quality of life of patients.
VL  - 2
IS  - 2
ER  -

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Author Information

Alireza Shamsabadi Masoudi

Department of Biomedical Engineering, University of Tehran, Tehran, Iran
Mohammad Sadegh Hassanli

Department of Exercise Physiology, Jahrom University, Jahrom, Iran
Zahra Taavili

Department of Mechanical Engineering, Jahrom University, Jahrom, Iran
Yasaman Sadeghizade

Department of Biomedical Engineering, University of Isfahan, Isfahan, Iran

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APA Style

Alireza Shamsabadi Masoudi, Mohammad Sadegh Hassanli, Zahra Taavili, Yasaman Sadeghizade. (2017). Biomedical and Micro-Robots: An Overview of Recent Developments. Chemical and Biomolecular Engineering, 2(2), 90-95. https://doi.org/10.11648/j.cbe.20170202.13

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ACS Style

Alireza Shamsabadi Masoudi; Mohammad Sadegh Hassanli; Zahra Taavili; Yasaman Sadeghizade. Biomedical and Micro-Robots: An Overview of Recent Developments. Chem. Biomol. Eng. 2017, 2(2), 90-95. doi: 10.11648/j.cbe.20170202.13

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AMA Style

Alireza Shamsabadi Masoudi, Mohammad Sadegh Hassanli, Zahra Taavili, Yasaman Sadeghizade. Biomedical and Micro-Robots: An Overview of Recent Developments. Chem Biomol Eng. 2017;2(2):90-95. doi: 10.11648/j.cbe.20170202.13

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@article{10.11648/j.cbe.20170202.13,
  author = {Alireza Shamsabadi Masoudi and Mohammad Sadegh Hassanli and Zahra Taavili and Yasaman Sadeghizade},
  title = {Biomedical and Micro-Robots: An Overview of Recent Developments},
  journal = {Chemical and Biomolecular Engineering},
  volume = {2},
  number = {2},
  pages = {90-95},
  doi = {10.11648/j.cbe.20170202.13},
  url = {https://doi.org/10.11648/j.cbe.20170202.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cbe.20170202.13},
  abstract = {This paper aims to provide an overview of recent challenges in the development of micro-robots for future biomedical applications. This paper first considers a comprehensive survey of the state-of-the-art in medical micro-robots. Consequently, it investigates the critical aspects and emerging ideas associated with designing of such medical micro-robots in order to navigate in viscous environments and inspire future research for healthcare applications. Potential biomedical micro-robots are used for a wide variety of applications into different organs of the patient's body, such as clearing heart occlusion, treatment of Nephrolithotomy, minimally invasive surgery, micromanipulative, released into the bloodstream and targeted drug delivery. Challenges and emerging concepts include functionality, powering, robot localization, communication and safety have been proposed, thereby leading to enable an extensive range of medical operations locomotion features, obtain and process information, being able to operate within specific constraints. This review provides details insight of medical micro-robot developments and the existing solutions for challenges and emerging concepts paving the way for designing such a medical micro-robot for operation inside, fast recovery and increased quality of life of patients.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Biomedical and Micro-Robots: An Overview of Recent Developments
AU  - Alireza Shamsabadi Masoudi
AU  - Mohammad Sadegh Hassanli
AU  - Zahra Taavili
AU  - Yasaman Sadeghizade
Y1  - 2017/03/04
PY  - 2017
N1  - https://doi.org/10.11648/j.cbe.20170202.13
DO  - 10.11648/j.cbe.20170202.13
T2  - Chemical and Biomolecular Engineering
JF  - Chemical and Biomolecular Engineering
JO  - Chemical and Biomolecular Engineering
SP  - 90
EP  - 95
PB  - Science Publishing Group
SN  - 2578-8884
UR  - https://doi.org/10.11648/j.cbe.20170202.13
AB  - This paper aims to provide an overview of recent challenges in the development of micro-robots for future biomedical applications. This paper first considers a comprehensive survey of the state-of-the-art in medical micro-robots. Consequently, it investigates the critical aspects and emerging ideas associated with designing of such medical micro-robots in order to navigate in viscous environments and inspire future research for healthcare applications. Potential biomedical micro-robots are used for a wide variety of applications into different organs of the patient's body, such as clearing heart occlusion, treatment of Nephrolithotomy, minimally invasive surgery, micromanipulative, released into the bloodstream and targeted drug delivery. Challenges and emerging concepts include functionality, powering, robot localization, communication and safety have been proposed, thereby leading to enable an extensive range of medical operations locomotion features, obtain and process information, being able to operate within specific constraints. This review provides details insight of medical micro-robot developments and the existing solutions for challenges and emerging concepts paving the way for designing such a medical micro-robot for operation inside, fast recovery and increased quality of life of patients.
VL  - 2
IS  - 2
ER  -

Copy | Download