High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A  Meta-analysis

Fulun Li; Ke Liu; Qianlong Zhao; Junyi Chen; Lingfei Liu; Qing-Mu Xie; Jing Yang

doi:doi:10.11648/j.crj.20190703.16

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High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A Meta-analysis

Fulun Li, Ke Liu, Qianlong Zhao, Junyi Chen, Lingfei Liu, Qing-Mu Xie, Jing Yang

Published in Cancer Research Journal (Volume 7, Issue 3)

Received: 27 August 2019 Accepted: 10 September 2019 Published: 24 September 2019

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Abstract

There are many researches on the correlation between C-reactive protein (CRP) and prognosis of gastric cancer, but whether CRP could be used as an evaluation indicator for prognosis of gastric cancer patients, which was still controversial. Therefore, we conducted meta-analysis based on 18 studies involving 3656 objects. The results show that, CRP was significantly correlated with the risk of poor prognosis of gastric cancer patients [HR (95%CI) 1.50 (1.24, 1.81) P=0.000], and the risk of the poor prognosis can be significantly increased when CRP>10mg/L. In the different clinical stage, high expression of CRP can increases the risk of poor prognosis. The CRP can be used as an important indicator of poor prognosis of gastric cancer patients.

Published in	Cancer Research Journal (Volume 7, Issue 3)
DOI	10.11648/j.crj.20190703.16
Page(s)	117-124
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

C-reactive Protein, Gastric Cancer, Prognosis, Meta-analysis

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APA Style

Fulun Li, Ke Liu, Qianlong Zhao, Junyi Chen, Lingfei Liu, et al. (2019). High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A Meta-analysis. Cancer Research Journal, 7(3), 117-124. https://doi.org/10.11648/j.crj.20190703.16

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ACS Style

Fulun Li; Ke Liu; Qianlong Zhao; Junyi Chen; Lingfei Liu, et al. High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A Meta-analysis. Cancer Res. J. 2019, 7(3), 117-124. doi: 10.11648/j.crj.20190703.16

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AMA Style

Fulun Li, Ke Liu, Qianlong Zhao, Junyi Chen, Lingfei Liu, et al. High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A Meta-analysis. Cancer Res J. 2019;7(3):117-124. doi: 10.11648/j.crj.20190703.16

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@article{10.11648/j.crj.20190703.16,
  author = {Fulun Li and Ke Liu and Qianlong Zhao and Junyi Chen and Lingfei Liu and Qing-Mu Xie and Jing Yang},
  title = {High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A  Meta-analysis},
  journal = {Cancer Research Journal},
  volume = {7},
  number = {3},
  pages = {117-124},
  doi = {10.11648/j.crj.20190703.16},
  url = {https://doi.org/10.11648/j.crj.20190703.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20190703.16},
  abstract = {There are many researches on the correlation between C-reactive protein (CRP) and prognosis of gastric cancer, but whether CRP could be used as an evaluation indicator for prognosis of gastric cancer patients, which was still controversial. Therefore, we conducted meta-analysis based on 18 studies involving 3656 objects. The results show that, CRP was significantly correlated with the risk of poor prognosis of gastric cancer patients [HR (95%CI) 1.50 (1.24, 1.81) P=0.000], and the risk of the poor prognosis can be significantly increased when CRP>10mg/L. In the different clinical stage, high expression of CRP can increases the risk of poor prognosis. The CRP can be used as an important indicator of poor prognosis of gastric cancer patients.},
 year = {2019}
}

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TY  - JOUR
T1  - High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A  Meta-analysis
AU  - Fulun Li
AU  - Ke Liu
AU  - Qianlong Zhao
AU  - Junyi Chen
AU  - Lingfei Liu
AU  - Qing-Mu Xie
AU  - Jing Yang
Y1  - 2019/09/24
PY  - 2019
N1  - https://doi.org/10.11648/j.crj.20190703.16
DO  - 10.11648/j.crj.20190703.16
T2  - Cancer Research Journal
JF  - Cancer Research Journal
JO  - Cancer Research Journal
SP  - 117
EP  - 124
PB  - Science Publishing Group
SN  - 2330-8214
UR  - https://doi.org/10.11648/j.crj.20190703.16
AB  - There are many researches on the correlation between C-reactive protein (CRP) and prognosis of gastric cancer, but whether CRP could be used as an evaluation indicator for prognosis of gastric cancer patients, which was still controversial. Therefore, we conducted meta-analysis based on 18 studies involving 3656 objects. The results show that, CRP was significantly correlated with the risk of poor prognosis of gastric cancer patients [HR (95%CI) 1.50 (1.24, 1.81) P=0.000], and the risk of the poor prognosis can be significantly increased when CRP>10mg/L. In the different clinical stage, high expression of CRP can increases the risk of poor prognosis. The CRP can be used as an important indicator of poor prognosis of gastric cancer patients.
VL  - 7
IS  - 3
ER  -

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Author Information

Fulun Li

Department of Child Development and Behavior, Children’s Hospital of Gansu Province/Lanzhou University Second Hospital, Lanzhou, China
Ke Liu

School of Applied Chemical Engineering, Lanzhou Petrochemical Polytechnic, Lanzhou, China
Qianlong Zhao

Department of Child Development and Behavior, Children’s Hospital of Gansu Province/Lanzhou University Second Hospital, Lanzhou, China
Junyi Chen

Department of Child Development and Behavior, Children’s Hospital of Gansu Province/Lanzhou University Second Hospital, Lanzhou, China
Lingfei Liu

School of Public Health, Lanzhou University, Laanzhou, China
Qing-Mu Xie

Department of Psychology, Tohoku University, Sendai, Japan
Jing Yang

Department of Child Development and Behavior, Children’s Hospital of Gansu Province/Lanzhou University Second Hospital, Lanzhou, China

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Plain Text BibTeX RIS

APA Style

Fulun Li, Ke Liu, Qianlong Zhao, Junyi Chen, Lingfei Liu, et al. (2019). High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A Meta-analysis. Cancer Research Journal, 7(3), 117-124. https://doi.org/10.11648/j.crj.20190703.16

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ACS Style

Fulun Li; Ke Liu; Qianlong Zhao; Junyi Chen; Lingfei Liu, et al. High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A Meta-analysis. Cancer Res. J. 2019, 7(3), 117-124. doi: 10.11648/j.crj.20190703.16

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AMA Style

Fulun Li, Ke Liu, Qianlong Zhao, Junyi Chen, Lingfei Liu, et al. High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A Meta-analysis. Cancer Res J. 2019;7(3):117-124. doi: 10.11648/j.crj.20190703.16

Copy | Download

@article{10.11648/j.crj.20190703.16,
  author = {Fulun Li and Ke Liu and Qianlong Zhao and Junyi Chen and Lingfei Liu and Qing-Mu Xie and Jing Yang},
  title = {High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A  Meta-analysis},
  journal = {Cancer Research Journal},
  volume = {7},
  number = {3},
  pages = {117-124},
  doi = {10.11648/j.crj.20190703.16},
  url = {https://doi.org/10.11648/j.crj.20190703.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20190703.16},
  abstract = {There are many researches on the correlation between C-reactive protein (CRP) and prognosis of gastric cancer, but whether CRP could be used as an evaluation indicator for prognosis of gastric cancer patients, which was still controversial. Therefore, we conducted meta-analysis based on 18 studies involving 3656 objects. The results show that, CRP was significantly correlated with the risk of poor prognosis of gastric cancer patients [HR (95%CI) 1.50 (1.24, 1.81) P=0.000], and the risk of the poor prognosis can be significantly increased when CRP>10mg/L. In the different clinical stage, high expression of CRP can increases the risk of poor prognosis. The CRP can be used as an important indicator of poor prognosis of gastric cancer patients.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - High Expression of C-reactive Protein Increases the Risk of Poor Prognosis in Patients with Gastric Cancer: A  Meta-analysis
AU  - Fulun Li
AU  - Ke Liu
AU  - Qianlong Zhao
AU  - Junyi Chen
AU  - Lingfei Liu
AU  - Qing-Mu Xie
AU  - Jing Yang
Y1  - 2019/09/24
PY  - 2019
N1  - https://doi.org/10.11648/j.crj.20190703.16
DO  - 10.11648/j.crj.20190703.16
T2  - Cancer Research Journal
JF  - Cancer Research Journal
JO  - Cancer Research Journal
SP  - 117
EP  - 124
PB  - Science Publishing Group
SN  - 2330-8214
UR  - https://doi.org/10.11648/j.crj.20190703.16
AB  - There are many researches on the correlation between C-reactive protein (CRP) and prognosis of gastric cancer, but whether CRP could be used as an evaluation indicator for prognosis of gastric cancer patients, which was still controversial. Therefore, we conducted meta-analysis based on 18 studies involving 3656 objects. The results show that, CRP was significantly correlated with the risk of poor prognosis of gastric cancer patients [HR (95%CI) 1.50 (1.24, 1.81) P=0.000], and the risk of the poor prognosis can be significantly increased when CRP>10mg/L. In the different clinical stage, high expression of CRP can increases the risk of poor prognosis. The CRP can be used as an important indicator of poor prognosis of gastric cancer patients.
VL  - 7
IS  - 3
ER  -

Copy | Download