Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress

Md. Ashiqur Rahman; Farida Arjuman; Shahida Alam; Mohammad Ibrahim Khalil; Quazi Habibullah; Khandakar A. B. M. Abdullah Al Hasan; Farhana Afroz; Nazneen Naher Aymon

doi:doi:10.11648/j.crj.20210901.20

Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress

Md. Ashiqur Rahman, Farida Arjuman, Shahida Alam, Mohammad Ibrahim Khalil, Quazi Habibullah, Khandakar A. B. M. Abdullah Al Hasan, Farhana Afroz, Nazneen Naher Aymon

Published in Cancer Research Journal (Volume 9, Issue 1)

Received: 26 January 2021 Accepted: 17 March 2021 Published: 30 March 2021

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Background: Lumpectomy and mastectomy remain the main surgical procedure of breast cancer as a part of treatment as well as management. This study was aimed to compare the early post-operative outcomes of lumpectomy (BCS) versus mastectomy (MRM). Methods: It was an observational study conducted at the Department of Surgical Oncology of National Institute of Cancer Research and Hospital (NICRH), Mohakhali, Dhaka, Bangladesh during the period from October 2016 to January 2019. The study sample consisted of 264 cancer patients who admitted in the hospital. The purposive sampling was done following inclusion criteria. Having collection of data, chi-square test was done to see the association of breast cancer among female patients. Results: Out of 264, 200 (75.75%) patients underwent mastectomy (MRM) and remaining percentage of patients underwent lumpectomy. The mean age of the patients was 37.69 (SD±10.31) and 44.82 (SD±7.65) in lumpectomy and mastectomy group respectively. Wound infection was present among 12.5% and 24% lumpectomy and mastectomy patients. Subsequently, seroma was present among 18.75% and 54% patients who underwent lumpectomy (BCS) and mastectomy (MRM) respectively which was statistically significant (P<0.014). Flap necrosis was found only among 16% mastectomy patients (P<0.04). There was significant difference in income and education among lumpectomy and mastectomy patients. However, the mean duration of hospital stay was 6.06±0.85 days and 17.70±4.70 days in lumpectomy (BCS) and mastectomy (MRM) group respectively which was statistically significant (P< 0.05). Conclusion: This study showed that lumpectomy (BCS) had early recovery and better post-operative treatment progress than mastectomy (MRM).

Published in	Cancer Research Journal (Volume 9, Issue 1)
DOI	10.11648/j.crj.20210901.20
Page(s)	79-84
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Bangladesh, Flap Necrosis, Lumpectomy, Mastectomy, Seroma

References

[1]	Angelique, FV & Lisa, AN., 2007, ‘Complications in breast surgery’, SurgClin N Am, vol. 87, pp. 431-451.
[2]	Bokhari I., Mehmood, Z., Nazeer, M., & Khan, A. 2010,‘Early complications of mastectomy with axillary clearance in patients with stage II and III carcinoma breast’ Journal of Surgery Pakistan (International, vol. 15 (4), pp. 182-185.
[3]	Chatterjee, A., Pyfer, B., Fisher, C., Czerniecki, B., Tchou, J., & Rosenkranz, K. 2015,‘Early postoperative outcomes in lumpectomy versus simple mastectomy’, Journal of Surgical Research, vol. 198, pp. 143-148.
[4]	El-Tamer, MB., Ward, BM., Schifftner, T., Neumayer, L., Khuri, S., & Henderson, W. 2007,‘Morbidity and mortality following breast cancer surgery in women: National benchmarks for standards of care’, Ann Surg, vol. 245 (5), pp. 665-671.
[5]	Fisher, B., Anderson, S., Bryant, J., 2002,‘Twenty year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer’, N Engl J Med, vol. 347, pp. 1233-1241.
[6]	Clarke, M., Collins, R., Darby, S., Devies, C., Godwin, J., Hicks, C., et al 2005 ‘Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-years survival: an overview of the randomised trials’ Lancet, vol. 366 (9503), pp. 2087-2106.
[7]	Gnant, M., Thomssen, C., & Harbeck. St. Gallen/Vienna 2015, ‘A brief summary of the consensus discussion’, BreastCare, vol. 10, pp. 124-130.
[8]	Rahman, MM., Ahsan, MA., Monalissa, NN., Rahman, K. 2014,‘Influence of Socioeconomic Status and BMI on the Quality of Life after Mastectomy in Bangladeshi Breast Cancer Patients in a public Hospital’, Japanese Journal of Clinical Oncology, vol. 44 (12), pp. 1150-1157.
[9]	Roststein, C., Farguson, R., Cumming, K. M., Piedmonte, M. R., Lucey, J., & Banish, A. 1992,‘Determinants of clean surgical wound infections for breast procedures at an oncology center’, Infect Control Hosp Epidemiol, vol. 161 (4), pp. 207-214.
[10]	Somers, RG., Jablon, LK., Sandler, GI., Rosenblatt, NK 1992,‘The use of closed suction drainage after lumpectomy and axillary node dissection for breast cancer: A prospective randomized trial’, Ann Surg, vol. 215, pp. 146-149.
[11]	Sorensen, L. T., Horby, J., Frilis, E., Pilsgaard, B., & Jorgensen, T. 2002,‘Smoking as a risk factor for wound healing and infection in breast cancer surgery’, Eur J Surg Oncol, vol. 28 (8), pp. 815-820.
[12]	Tiwari, S., Reeni, M., Trichal, VK., Nigam, RK., Rai, A., Balani, S. 2015, ‘Breast Cancer: Correlation of Molecular Classification with Clinicohistopathology,‘Scholars Journal of Applied Medical sciences’, vol. 3 (2G), pp. 1018-1026.
[13]	Torre, LA., Bray, F., Siegel, L., Ferlay, J., Loret-Tieutel, J., Jemal, A. 2015, ‘Global cancer statistics, 2012, CA: A Cancer J Clin, vol. 65 (2), pp. 87-108.
[14]	Veronesi, U., Cascinelli, N., Mariani, L., et al. 2002,‘Twenty year follow-up of a randomized study comparing breast conserving surgery with radical mastectomy for early breast cancer’, N Engl J Med, vol. 347 (16), pp. 1227-1232.
[15]	Vinton, AL., Traverso, LW., & Jolly, P. C. 1991,‘Wound complication after modified radical mastectomy compared with tylectomy with axillary lymph node dissection’, Am J Surg, vol. 161 (5), pp. 584-587.
[16]	WHO 2016, Retrieved August 20, 2016, from WHO Website: http://www.who.int/cancer/detection/breastcancer/en/index1.html
[17]	Thompsom, AM. 1999, ‘How I do it. Axillary node clearance for breast cancer’ J R Coll Surg Edinberg, vol. 44 (2), pp. 111-116.
[18]	Kumar, S., Lal, B and Misra, MC, 1995, ‘Post mastectomy seroma; a new look into the aetiology of an old problem’, world J R coll Surg Edin, vol, 40, pp. 492-496.
[19]	Ozaslan, C., & Kuru, B. 2004, ‘Lymphedema after treatment of breast cancer’, am J Surg, vol. 187, pp. 69-72.

Cite This Article

Plain Text BibTeX RIS

APA Style

Md. Ashiqur Rahman, Farida Arjuman, Shahida Alam, Mohammad Ibrahim Khalil, Quazi Habibullah, et al. (2021). Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress. Cancer Research Journal, 9(1), 79-84. https://doi.org/10.11648/j.crj.20210901.20

Copy | Download

ACS Style

Md. Ashiqur Rahman; Farida Arjuman; Shahida Alam; Mohammad Ibrahim Khalil; Quazi Habibullah, et al. Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress. Cancer Res. J. 2021, 9(1), 79-84. doi: 10.11648/j.crj.20210901.20

Copy | Download

AMA Style

Md. Ashiqur Rahman, Farida Arjuman, Shahida Alam, Mohammad Ibrahim Khalil, Quazi Habibullah, et al. Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress. Cancer Res J. 2021;9(1):79-84. doi: 10.11648/j.crj.20210901.20

Copy | Download

@article{10.11648/j.crj.20210901.20,
  author = {Md. Ashiqur Rahman and Farida Arjuman and Shahida Alam and Mohammad Ibrahim Khalil and Quazi Habibullah and Khandakar A. B. M. Abdullah Al Hasan and Farhana Afroz and Nazneen Naher Aymon},
  title = {Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress},
  journal = {Cancer Research Journal},
  volume = {9},
  number = {1},
  pages = {79-84},
  doi = {10.11648/j.crj.20210901.20},
  url = {https://doi.org/10.11648/j.crj.20210901.20},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20210901.20},
  abstract = {Background: Lumpectomy and mastectomy remain the main surgical procedure of breast cancer as a part of treatment as well as management. This study was aimed to compare the early post-operative outcomes of lumpectomy (BCS) versus mastectomy (MRM). Methods: It was an observational study conducted at the Department of Surgical Oncology of National Institute of Cancer Research and Hospital (NICRH), Mohakhali, Dhaka, Bangladesh during the period from October 2016 to January 2019. The study sample consisted of 264 cancer patients who admitted in the hospital. The purposive sampling was done following inclusion criteria. Having collection of data, chi-square test was done to see the association of breast cancer among female patients. Results: Out of 264, 200 (75.75%) patients underwent mastectomy (MRM) and remaining percentage of patients underwent lumpectomy. The mean age of the patients was 37.69 (SD±10.31) and 44.82 (SD±7.65) in lumpectomy and mastectomy group respectively. Wound infection was present among 12.5% and 24% lumpectomy and mastectomy patients. Subsequently, seroma was present among 18.75% and 54% patients who underwent lumpectomy (BCS) and mastectomy (MRM) respectively which was statistically significant (PConclusion: This study showed that lumpectomy (BCS) had early recovery and better post-operative treatment progress than mastectomy (MRM).},
 year = {2021}
}

Copy | Download

TY - JOUR
T1 - Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress
AU - Md. Ashiqur Rahman
AU - Farida Arjuman
AU - Shahida Alam
AU - Mohammad Ibrahim Khalil
AU - Quazi Habibullah
AU - Khandakar A. B. M. Abdullah Al Hasan
AU - Farhana Afroz
AU - Nazneen Naher Aymon
Y1 - 2021/03/30
PY - 2021
N1 - https://doi.org/10.11648/j.crj.20210901.20
DO - 10.11648/j.crj.20210901.20
T2 - Cancer Research Journal
JF - Cancer Research Journal
JO - Cancer Research Journal
SP - 79
EP - 84
PB - Science Publishing Group
SN - 2330-8214
UR - https://doi.org/10.11648/j.crj.20210901.20
AB - Background: Lumpectomy and mastectomy remain the main surgical procedure of breast cancer as a part of treatment as well as management. This study was aimed to compare the early post-operative outcomes of lumpectomy (BCS) versus mastectomy (MRM). Methods: It was an observational study conducted at the Department of Surgical Oncology of National Institute of Cancer Research and Hospital (NICRH), Mohakhali, Dhaka, Bangladesh during the period from October 2016 to January 2019. The study sample consisted of 264 cancer patients who admitted in the hospital. The purposive sampling was done following inclusion criteria. Having collection of data, chi-square test was done to see the association of breast cancer among female patients. Results: Out of 264, 200 (75.75%) patients underwent mastectomy (MRM) and remaining percentage of patients underwent lumpectomy. The mean age of the patients was 37.69 (SD±10.31) and 44.82 (SD±7.65) in lumpectomy and mastectomy group respectively. Wound infection was present among 12.5% and 24% lumpectomy and mastectomy patients. Subsequently, seroma was present among 18.75% and 54% patients who underwent lumpectomy (BCS) and mastectomy (MRM) respectively which was statistically significant (PConclusion: This study showed that lumpectomy (BCS) had early recovery and better post-operative treatment progress than mastectomy (MRM).
VL - 9
IS - 1
ER -

Copy | Download

Author Information

Md. Ashiqur Rahman

Department of Surgical Oncology, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka, Bangladesh
Farida Arjuman

Histopathology, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka, Bangladesh
Shahida Alam

Department of Radiation Oncology, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka, Bangladesh
Mohammad Ibrahim Khalil

Department of Surgery, Dhaka Medical College, Dhaka, Bangladesh
Quazi Habibullah

Surgery, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka, Bangladesh
Khandakar A. B. M. Abdullah Al Hasan

Department of Surgical Oncology, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka, Bangladesh
Farhana Afroz

Department of Biochemistry, Sheikh Hasina National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh
Nazneen Naher Aymon

Pathology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Md. Ashiqur Rahman, Farida Arjuman, Shahida Alam, Mohammad Ibrahim Khalil, Quazi Habibullah, et al. (2021). Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress. Cancer Research Journal, 9(1), 79-84. https://doi.org/10.11648/j.crj.20210901.20

Copy | Download

ACS Style

Md. Ashiqur Rahman; Farida Arjuman; Shahida Alam; Mohammad Ibrahim Khalil; Quazi Habibullah, et al. Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress. Cancer Res. J. 2021, 9(1), 79-84. doi: 10.11648/j.crj.20210901.20

Copy | Download

AMA Style

Md. Ashiqur Rahman, Farida Arjuman, Shahida Alam, Mohammad Ibrahim Khalil, Quazi Habibullah, et al. Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress. Cancer Res J. 2021;9(1):79-84. doi: 10.11648/j.crj.20210901.20

Copy | Download

@article{10.11648/j.crj.20210901.20,
  author = {Md. Ashiqur Rahman and Farida Arjuman and Shahida Alam and Mohammad Ibrahim Khalil and Quazi Habibullah and Khandakar A. B. M. Abdullah Al Hasan and Farhana Afroz and Nazneen Naher Aymon},
  title = {Lumpectomy Versus Mastectomy in Breast Cancer: Comparison of Postoperative Consequences and Treatment Progress},
  journal = {Cancer Research Journal},
  volume = {9},
  number = {1},
  pages = {79-84},
  doi = {10.11648/j.crj.20210901.20},
  url = {https://doi.org/10.11648/j.crj.20210901.20},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20210901.20},
  abstract = {Background: Lumpectomy and mastectomy remain the main surgical procedure of breast cancer as a part of treatment as well as management. This study was aimed to compare the early post-operative outcomes of lumpectomy (BCS) versus mastectomy (MRM). Methods: It was an observational study conducted at the Department of Surgical Oncology of National Institute of Cancer Research and Hospital (NICRH), Mohakhali, Dhaka, Bangladesh during the period from October 2016 to January 2019. The study sample consisted of 264 cancer patients who admitted in the hospital. The purposive sampling was done following inclusion criteria. Having collection of data, chi-square test was done to see the association of breast cancer among female patients. Results: Out of 264, 200 (75.75%) patients underwent mastectomy (MRM) and remaining percentage of patients underwent lumpectomy. The mean age of the patients was 37.69 (SD±10.31) and 44.82 (SD±7.65) in lumpectomy and mastectomy group respectively. Wound infection was present among 12.5% and 24% lumpectomy and mastectomy patients. Subsequently, seroma was present among 18.75% and 54% patients who underwent lumpectomy (BCS) and mastectomy (MRM) respectively which was statistically significant (PConclusion: This study showed that lumpectomy (BCS) had early recovery and better post-operative treatment progress than mastectomy (MRM).},
 year = {2021}
}

Copy | Download