Background: TNE-GEPs are rare and originate in the endocrine system located in the gastrointestinal tract (carcinoids) and in the pancreas (island tumours) with a variety of clinical presentations. Design: Cooperative, retrospective. Method: Between January 2005 and December 2018, a cooperative work in the Central Guard Service of the HNC, General Surgery Service "Pablo Luis Mirizzi" of the HNC and Caraffa Private Clinic, 24 patients with TNE-GEP were surgically intervened. Of the total, 14 belonged to the female sex (58.3%) and the remaining 10 men (41.6%), with an age range between 20 and 82 years of age with an average of 55.3 years. Results: The locations were 4 stomachs (16.6%), 14 in the intestine (58.3%) and finally 6 in the head of the pancreas (25%). In relation to the stomach in the 4 patients a total gastrectomy was performed and the pathological anatomy in three demonstrated low-grade neuroendocrine carcinoma and the fourth high degree, the latter dying. 5 patients with clinical presentations of acute appendicitis. The pathological anatomy was further acute appendicitis, a low-grade neuroendocrine carcinoma. In ileum-cecal region, four of it performed right colectomy. In three were low-grade living and fourth high-grade carcinoma with liver mtts who died. In three of the ileum all were occlusive, carrying out intestinal resections, in two low- and last-grade moderate-grade carcinomas with living liver mtts. The colon tumours were, one ascending with hepatic mtts and right colectomy more liver resections, with pathological anatomy being high-grade carcinoma and another a low-grade descending colon. The 6 pancreas lesions, 3 were non-functioning and three other functioning. All patients were operated of CPD. Conclusion: TNE-GEP is a rare pathology but whose frequency is constant onset. With improved imaging methods, we are faced with an increase in preoperative presumption and in the face of its best oncological possibilities, a pathology that every surgeon must know and think about.
| Published in | Cancer Research Journal (Volume 9, Issue 4) |
| DOI | 10.11648/j.crj.20210904.13 |
| Page(s) | 196-201 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
TNE-GEPs Are Rare, Endocrine System Located in the Gastrointestinal Tract, Surgical Treatment
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APA Style
Paul Eduardo Lada, Casares Gonzalo, Mariot Daniela, Janikow Christian, Saliba Jorge, et al. (2021). Neuroendocrine Tumours of Gastrointestinal Tract: Our Experience. Cancer Research Journal, 9(4), 196-201. https://doi.org/10.11648/j.crj.20210904.13
ACS Style
Paul Eduardo Lada; Casares Gonzalo; Mariot Daniela; Janikow Christian; Saliba Jorge, et al. Neuroendocrine Tumours of Gastrointestinal Tract: Our Experience. Cancer Res. J. 2021, 9(4), 196-201. doi: 10.11648/j.crj.20210904.13
AMA Style
Paul Eduardo Lada, Casares Gonzalo, Mariot Daniela, Janikow Christian, Saliba Jorge, et al. Neuroendocrine Tumours of Gastrointestinal Tract: Our Experience. Cancer Res J. 2021;9(4):196-201. doi: 10.11648/j.crj.20210904.13
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author = {Paul Eduardo Lada and Casares Gonzalo and Mariot Daniela and Janikow Christian and Saliba Jorge and Martínez Julián and Santiago Carrizo and Abril Giménez and Francisco Flórez},
title = {Neuroendocrine Tumours of Gastrointestinal Tract: Our Experience},
journal = {Cancer Research Journal},
volume = {9},
number = {4},
pages = {196-201},
doi = {10.11648/j.crj.20210904.13},
url = {https://doi.org/10.11648/j.crj.20210904.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20210904.13},
abstract = {Background: TNE-GEPs are rare and originate in the endocrine system located in the gastrointestinal tract (carcinoids) and in the pancreas (island tumours) with a variety of clinical presentations. Design: Cooperative, retrospective. Method: Between January 2005 and December 2018, a cooperative work in the Central Guard Service of the HNC, General Surgery Service "Pablo Luis Mirizzi" of the HNC and Caraffa Private Clinic, 24 patients with TNE-GEP were surgically intervened. Of the total, 14 belonged to the female sex (58.3%) and the remaining 10 men (41.6%), with an age range between 20 and 82 years of age with an average of 55.3 years. Results: The locations were 4 stomachs (16.6%), 14 in the intestine (58.3%) and finally 6 in the head of the pancreas (25%). In relation to the stomach in the 4 patients a total gastrectomy was performed and the pathological anatomy in three demonstrated low-grade neuroendocrine carcinoma and the fourth high degree, the latter dying. 5 patients with clinical presentations of acute appendicitis. The pathological anatomy was further acute appendicitis, a low-grade neuroendocrine carcinoma. In ileum-cecal region, four of it performed right colectomy. In three were low-grade living and fourth high-grade carcinoma with liver mtts who died. In three of the ileum all were occlusive, carrying out intestinal resections, in two low- and last-grade moderate-grade carcinomas with living liver mtts. The colon tumours were, one ascending with hepatic mtts and right colectomy more liver resections, with pathological anatomy being high-grade carcinoma and another a low-grade descending colon. The 6 pancreas lesions, 3 were non-functioning and three other functioning. All patients were operated of CPD. Conclusion: TNE-GEP is a rare pathology but whose frequency is constant onset. With improved imaging methods, we are faced with an increase in preoperative presumption and in the face of its best oncological possibilities, a pathology that every surgeon must know and think about.},
year = {2021}
}
TY - JOUR T1 - Neuroendocrine Tumours of Gastrointestinal Tract: Our Experience AU - Paul Eduardo Lada AU - Casares Gonzalo AU - Mariot Daniela AU - Janikow Christian AU - Saliba Jorge AU - Martínez Julián AU - Santiago Carrizo AU - Abril Giménez AU - Francisco Flórez Y1 - 2021/12/24 PY - 2021 N1 - https://doi.org/10.11648/j.crj.20210904.13 DO - 10.11648/j.crj.20210904.13 T2 - Cancer Research Journal JF - Cancer Research Journal JO - Cancer Research Journal SP - 196 EP - 201 PB - Science Publishing Group SN - 2330-8214 UR - https://doi.org/10.11648/j.crj.20210904.13 AB - Background: TNE-GEPs are rare and originate in the endocrine system located in the gastrointestinal tract (carcinoids) and in the pancreas (island tumours) with a variety of clinical presentations. Design: Cooperative, retrospective. Method: Between January 2005 and December 2018, a cooperative work in the Central Guard Service of the HNC, General Surgery Service "Pablo Luis Mirizzi" of the HNC and Caraffa Private Clinic, 24 patients with TNE-GEP were surgically intervened. Of the total, 14 belonged to the female sex (58.3%) and the remaining 10 men (41.6%), with an age range between 20 and 82 years of age with an average of 55.3 years. Results: The locations were 4 stomachs (16.6%), 14 in the intestine (58.3%) and finally 6 in the head of the pancreas (25%). In relation to the stomach in the 4 patients a total gastrectomy was performed and the pathological anatomy in three demonstrated low-grade neuroendocrine carcinoma and the fourth high degree, the latter dying. 5 patients with clinical presentations of acute appendicitis. The pathological anatomy was further acute appendicitis, a low-grade neuroendocrine carcinoma. In ileum-cecal region, four of it performed right colectomy. In three were low-grade living and fourth high-grade carcinoma with liver mtts who died. In three of the ileum all were occlusive, carrying out intestinal resections, in two low- and last-grade moderate-grade carcinomas with living liver mtts. The colon tumours were, one ascending with hepatic mtts and right colectomy more liver resections, with pathological anatomy being high-grade carcinoma and another a low-grade descending colon. The 6 pancreas lesions, 3 were non-functioning and three other functioning. All patients were operated of CPD. Conclusion: TNE-GEP is a rare pathology but whose frequency is constant onset. With improved imaging methods, we are faced with an increase in preoperative presumption and in the face of its best oncological possibilities, a pathology that every surgeon must know and think about. VL - 9 IS - 4 ER -
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