Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials

Yasser Assem; A. I. Khalaf

doi:doi:10.11648/j.css.20170202.14

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Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials

Yasser Assem, A. I. Khalaf

Published in Colloid and Surface Science (Volume 2, Issue 2)

Received: 31 January 2017 Accepted: 20 February 2017 Published: 3 March 2017

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Abstract

Quaternized PDMAEMA (qPDMAEMA) was used to prepare nanofibers by electrospinning. At first the DMAEMA monomer was quaternized using Hexyl, dodecyl and hexadecyl bromide. Then the quaternized DMAEMA was polymerized by free radical polymerization. This polymer was characterized by 1HNMR, GPC, and thermal analysis (DSC and TGA). The (qPDMAEMA) was blended with PVA in different ratios (20/80, 25/75 and 50/50). The antibacterial properties of the prepared blends were examined against two strains type, the gram positive M. luteus and the gram negative E.coli. The antimicrobial activity showed that all blends with different alkyl side chain length (i.e. 6, 12, and 16) are highly active against M. luteus and no growth of the bacteria was observed after incubation period of 96 h, but in case of E. coli, the antibacterial activity is different. The blend having short alkyl side chain (6) are very active and can kill all the bacteria colonies. Blends that contain longer side chains are mostly inactive. However the blend compositions of PVA/PDMAEMA-12 (80/20 and 75/25) exhibit a good antimicrobial effect against E. Coli. The minimum bactericidal concentration (MBC) was obtained by determining the minimum polymer concentration at which no growth was observed. qPDMAEMA based fibers were produced using a solution blend of PDMAEMA and PVA. The quaternized PDEAMMAs/PVA blends were electrospun in ethanol. The concentration of the polymer was as high as 20% in order to get fibers. The diameter of formed fibers was found to be around 500 nm.

Published in	Colloid and Surface Science (Volume 2, Issue 2)
DOI	10.11648/j.css.20170202.14
Page(s)	66-75
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Nanofibers, PDMAEMA, Electrospinning, Antibaterial Polymers, Free Radical Polymerization

References

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Yasser Assem, A. I. Khalaf. (2017). Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials. Colloid and Surface Science, 2(2), 66-75. https://doi.org/10.11648/j.css.20170202.14

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Yasser Assem; A. I. Khalaf. Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials. Colloid Surf. Sci. 2017, 2(2), 66-75. doi: 10.11648/j.css.20170202.14

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AMA Style

Yasser Assem, A. I. Khalaf. Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials. Colloid Surf Sci. 2017;2(2):66-75. doi: 10.11648/j.css.20170202.14

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@article{10.11648/j.css.20170202.14,
  author = {Yasser Assem and A. I. Khalaf},
  title = {Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials},
  journal = {Colloid and Surface Science},
  volume = {2},
  number = {2},
  pages = {66-75},
  doi = {10.11648/j.css.20170202.14},
  url = {https://doi.org/10.11648/j.css.20170202.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.css.20170202.14},
  abstract = {Quaternized PDMAEMA (qPDMAEMA) was used to prepare nanofibers by electrospinning. At first the DMAEMA monomer was quaternized using Hexyl, dodecyl and hexadecyl bromide. Then the quaternized DMAEMA was polymerized by free radical polymerization. This polymer was characterized by 1HNMR, GPC, and thermal analysis (DSC and TGA). The (qPDMAEMA) was blended with PVA in different ratios (20/80, 25/75 and 50/50). The antibacterial properties of the prepared blends were examined against two strains type, the gram positive M. luteus and the gram negative E.coli. The antimicrobial activity showed that all blends with different alkyl side chain length (i.e. 6, 12, and 16) are highly active against M. luteus and no growth of the bacteria was observed after incubation period of 96 h, but in case of E. coli, the antibacterial activity is different. The blend having short alkyl side chain (6) are very active and can kill all the bacteria colonies. Blends that contain longer side chains are mostly inactive. However the blend compositions of PVA/PDMAEMA-12 (80/20 and 75/25) exhibit a good antimicrobial effect against E. Coli. The minimum bactericidal concentration (MBC) was obtained by determining the minimum polymer concentration at which no growth was observed. qPDMAEMA based fibers were produced using a solution blend of PDMAEMA and PVA. The quaternized PDEAMMAs/PVA blends were electrospun in ethanol. The concentration of the polymer was as high as 20% in order to get fibers. The diameter of formed fibers was found to be around 500 nm.},
 year = {2017}
}

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TY - JOUR
T1 - Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials
AU - Yasser Assem
AU - A. I. Khalaf
Y1 - 2017/03/03
PY - 2017
N1 - https://doi.org/10.11648/j.css.20170202.14
DO - 10.11648/j.css.20170202.14
T2 - Colloid and Surface Science
JF - Colloid and Surface Science
JO - Colloid and Surface Science
SP - 66
EP - 75
PB - Science Publishing Group
SN - 2578-9236
UR - https://doi.org/10.11648/j.css.20170202.14
AB - Quaternized PDMAEMA (qPDMAEMA) was used to prepare nanofibers by electrospinning. At first the DMAEMA monomer was quaternized using Hexyl, dodecyl and hexadecyl bromide. Then the quaternized DMAEMA was polymerized by free radical polymerization. This polymer was characterized by 1HNMR, GPC, and thermal analysis (DSC and TGA). The (qPDMAEMA) was blended with PVA in different ratios (20/80, 25/75 and 50/50). The antibacterial properties of the prepared blends were examined against two strains type, the gram positive M. luteus and the gram negative E.coli. The antimicrobial activity showed that all blends with different alkyl side chain length (i.e. 6, 12, and 16) are highly active against M. luteus and no growth of the bacteria was observed after incubation period of 96 h, but in case of E. coli, the antibacterial activity is different. The blend having short alkyl side chain (6) are very active and can kill all the bacteria colonies. Blends that contain longer side chains are mostly inactive. However the blend compositions of PVA/PDMAEMA-12 (80/20 and 75/25) exhibit a good antimicrobial effect against E. Coli. The minimum bactericidal concentration (MBC) was obtained by determining the minimum polymer concentration at which no growth was observed. qPDMAEMA based fibers were produced using a solution blend of PDMAEMA and PVA. The quaternized PDEAMMAs/PVA blends were electrospun in ethanol. The concentration of the polymer was as high as 20% in order to get fibers. The diameter of formed fibers was found to be around 500 nm.
VL - 2
IS - 2
ER -

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Author Information

Yasser Assem

Department of Polymers and Pigments, National Research Centre, Dokki, Giza, Egypt
A. I. Khalaf

Department of Polymers and Pigments, National Research Centre, Dokki, Giza, Egypt

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APA Style

Yasser Assem, A. I. Khalaf. (2017). Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials. Colloid and Surface Science, 2(2), 66-75. https://doi.org/10.11648/j.css.20170202.14

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ACS Style

Yasser Assem; A. I. Khalaf. Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials. Colloid Surf. Sci. 2017, 2(2), 66-75. doi: 10.11648/j.css.20170202.14

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AMA Style

Yasser Assem, A. I. Khalaf. Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials. Colloid Surf Sci. 2017;2(2):66-75. doi: 10.11648/j.css.20170202.14

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@article{10.11648/j.css.20170202.14,
  author = {Yasser Assem and A. I. Khalaf},
  title = {Preparation and Characterization of Polymeric Nanofibers by Electrospinning as Potential Antibacterial Materials},
  journal = {Colloid and Surface Science},
  volume = {2},
  number = {2},
  pages = {66-75},
  doi = {10.11648/j.css.20170202.14},
  url = {https://doi.org/10.11648/j.css.20170202.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.css.20170202.14},
  abstract = {Quaternized PDMAEMA (qPDMAEMA) was used to prepare nanofibers by electrospinning. At first the DMAEMA monomer was quaternized using Hexyl, dodecyl and hexadecyl bromide. Then the quaternized DMAEMA was polymerized by free radical polymerization. This polymer was characterized by 1HNMR, GPC, and thermal analysis (DSC and TGA). The (qPDMAEMA) was blended with PVA in different ratios (20/80, 25/75 and 50/50). The antibacterial properties of the prepared blends were examined against two strains type, the gram positive M. luteus and the gram negative E.coli. The antimicrobial activity showed that all blends with different alkyl side chain length (i.e. 6, 12, and 16) are highly active against M. luteus and no growth of the bacteria was observed after incubation period of 96 h, but in case of E. coli, the antibacterial activity is different. The blend having short alkyl side chain (6) are very active and can kill all the bacteria colonies. Blends that contain longer side chains are mostly inactive. However the blend compositions of PVA/PDMAEMA-12 (80/20 and 75/25) exhibit a good antimicrobial effect against E. Coli. The minimum bactericidal concentration (MBC) was obtained by determining the minimum polymer concentration at which no growth was observed. qPDMAEMA based fibers were produced using a solution blend of PDMAEMA and PVA. The quaternized PDEAMMAs/PVA blends were electrospun in ethanol. The concentration of the polymer was as high as 20% in order to get fibers. The diameter of formed fibers was found to be around 500 nm.},
 year = {2017}
}

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