Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients

Mwenze Didier; Kyabu Veronique; Mukalay Abdon; Kalenga Prosper; Ilunga Julien

doi:doi:10.11648/j.ijcocr.20190403.11

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Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients

Mwenze Didier, Kyabu Veronique, Mukalay Abdon, Kalenga Prosper, Ilunga Julien

Published in International Journal of Clinical Oncology and Cancer Research (Volume 4, Issue 3)

Received: 13 August 2019 Accepted: 5 September 2019 Published: 18 September 2019

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Abstract

The aim of this study is to show the relationship between the index of Papillomavirus infection and the grade of cervical intraepithelial neoplasia as proposed by WHO in Lubumbashi patients. This is a cross-sectional analytical study on cervical biopsies whose histological diagnosis is an intraepithelial neoplasia registered in two Laboratory of Patholoy in Lubumbashi for a period of two years from June 2017 to June 2019. The following results were observed: A total of 41 cases of intraepithelial neoplasia were recorded out of 91 cervical biopsies is 43.2%. Five indices of Human Papillomavirus infection are found in Lubumbashi patients in variable proportions without statistically significant difference; that is the index (5) in 29.27%, the indices (7) and (9) in 21.95% for each index, the index (6) in 17.07% and the index (8) in 9.76%. The three grades of intraepithelial neoplasia proposed by the WHO since 2003 are also found in Lubumbashi patients in varying proportions with no statistically significant difference; 48.78% for grade 3; 36.59% for grade 2 and 14.63% for grade 1. There is no relationship between the HPV infection index and the grade of cervical intraepithelial neoplasia; calculated linear correlation r ^ 2 is equal to 0.00.

Published in	International Journal of Clinical Oncology and Cancer Research (Volume 4, Issue 3)
DOI	10.11648/j.ijcocr.20190403.11
Page(s)	29-33
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Papillomavirus Index, Intra-Epithelial Neoplasia, Grade

References

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APA Style

Mwenze Didier, Kyabu Veronique, Mukalay Abdon, Kalenga Prosper, Ilunga Julien. (2019). Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients. International Journal of Clinical Oncology and Cancer Research, 4(3), 29-33. https://doi.org/10.11648/j.ijcocr.20190403.11

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ACS Style

Mwenze Didier; Kyabu Veronique; Mukalay Abdon; Kalenga Prosper; Ilunga Julien. Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients. Int. J. Clin. Oncol. Cancer Res. 2019, 4(3), 29-33. doi: 10.11648/j.ijcocr.20190403.11

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AMA Style

Mwenze Didier, Kyabu Veronique, Mukalay Abdon, Kalenga Prosper, Ilunga Julien. Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients. Int J Clin Oncol Cancer Res. 2019;4(3):29-33. doi: 10.11648/j.ijcocr.20190403.11

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@article{10.11648/j.ijcocr.20190403.11,
  author = {Mwenze Didier and Kyabu Veronique and Mukalay Abdon and Kalenga Prosper and Ilunga Julien},
  title = {Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients},
  journal = {International Journal of Clinical Oncology and Cancer Research},
  volume = {4},
  number = {3},
  pages = {29-33},
  doi = {10.11648/j.ijcocr.20190403.11},
  url = {https://doi.org/10.11648/j.ijcocr.20190403.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20190403.11},
  abstract = {The aim of this study is to show the relationship between the index of Papillomavirus infection and the grade of cervical intraepithelial neoplasia as proposed by WHO in Lubumbashi patients. This is a cross-sectional analytical study on cervical biopsies whose histological diagnosis is an intraepithelial neoplasia registered in two Laboratory of Patholoy in Lubumbashi for a period of two years from June 2017 to June 2019. The following results were observed: A total of 41 cases of intraepithelial neoplasia were recorded out of 91 cervical biopsies is 43.2%. Five indices of Human Papillomavirus infection are found in Lubumbashi patients in variable proportions without statistically significant difference; that is the index (5) in 29.27%, the indices (7) and (9) in 21.95% for each index, the index (6) in 17.07% and the index (8) in 9.76%. The three grades of intraepithelial neoplasia proposed by the WHO since 2003 are also found in Lubumbashi patients in varying proportions with no statistically significant difference; 48.78% for grade 3; 36.59% for grade 2 and 14.63% for grade 1. There is no relationship between the HPV infection index and the grade of cervical intraepithelial neoplasia; calculated linear correlation r ^ 2 is equal to 0.00.},
 year = {2019}
}

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TY  - JOUR
T1  - Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients
AU  - Mwenze Didier
AU  - Kyabu Veronique
AU  - Mukalay Abdon
AU  - Kalenga Prosper
AU  - Ilunga Julien
Y1  - 2019/09/18
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcocr.20190403.11
DO  - 10.11648/j.ijcocr.20190403.11
T2  - International Journal of Clinical Oncology and Cancer Research
JF  - International Journal of Clinical Oncology and Cancer Research
JO  - International Journal of Clinical Oncology and Cancer Research
SP  - 29
EP  - 33
PB  - Science Publishing Group
SN  - 2578-9511
UR  - https://doi.org/10.11648/j.ijcocr.20190403.11
AB  - The aim of this study is to show the relationship between the index of Papillomavirus infection and the grade of cervical intraepithelial neoplasia as proposed by WHO in Lubumbashi patients. This is a cross-sectional analytical study on cervical biopsies whose histological diagnosis is an intraepithelial neoplasia registered in two Laboratory of Patholoy in Lubumbashi for a period of two years from June 2017 to June 2019. The following results were observed: A total of 41 cases of intraepithelial neoplasia were recorded out of 91 cervical biopsies is 43.2%. Five indices of Human Papillomavirus infection are found in Lubumbashi patients in variable proportions without statistically significant difference; that is the index (5) in 29.27%, the indices (7) and (9) in 21.95% for each index, the index (6) in 17.07% and the index (8) in 9.76%. The three grades of intraepithelial neoplasia proposed by the WHO since 2003 are also found in Lubumbashi patients in varying proportions with no statistically significant difference; 48.78% for grade 3; 36.59% for grade 2 and 14.63% for grade 1. There is no relationship between the HPV infection index and the grade of cervical intraepithelial neoplasia; calculated linear correlation r ^ 2 is equal to 0.00.
VL  - 4
IS  - 3
ER  -

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Author Information

Mwenze Didier

Department of Pathology, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Kyabu Veronique

Department of Pathology, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Mukalay Abdon

Department of Public Health, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Kalenga Prosper

Department of Gynecology Obstetrics, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Ilunga Julien

Department of Pathology, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

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APA Style

Mwenze Didier, Kyabu Veronique, Mukalay Abdon, Kalenga Prosper, Ilunga Julien. (2019). Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients. International Journal of Clinical Oncology and Cancer Research, 4(3), 29-33. https://doi.org/10.11648/j.ijcocr.20190403.11

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ACS Style

Mwenze Didier; Kyabu Veronique; Mukalay Abdon; Kalenga Prosper; Ilunga Julien. Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients. Int. J. Clin. Oncol. Cancer Res. 2019, 4(3), 29-33. doi: 10.11648/j.ijcocr.20190403.11

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AMA Style

Mwenze Didier, Kyabu Veronique, Mukalay Abdon, Kalenga Prosper, Ilunga Julien. Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients. Int J Clin Oncol Cancer Res. 2019;4(3):29-33. doi: 10.11648/j.ijcocr.20190403.11

Copy | Download

@article{10.11648/j.ijcocr.20190403.11,
  author = {Mwenze Didier and Kyabu Veronique and Mukalay Abdon and Kalenga Prosper and Ilunga Julien},
  title = {Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients},
  journal = {International Journal of Clinical Oncology and Cancer Research},
  volume = {4},
  number = {3},
  pages = {29-33},
  doi = {10.11648/j.ijcocr.20190403.11},
  url = {https://doi.org/10.11648/j.ijcocr.20190403.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20190403.11},
  abstract = {The aim of this study is to show the relationship between the index of Papillomavirus infection and the grade of cervical intraepithelial neoplasia as proposed by WHO in Lubumbashi patients. This is a cross-sectional analytical study on cervical biopsies whose histological diagnosis is an intraepithelial neoplasia registered in two Laboratory of Patholoy in Lubumbashi for a period of two years from June 2017 to June 2019. The following results were observed: A total of 41 cases of intraepithelial neoplasia were recorded out of 91 cervical biopsies is 43.2%. Five indices of Human Papillomavirus infection are found in Lubumbashi patients in variable proportions without statistically significant difference; that is the index (5) in 29.27%, the indices (7) and (9) in 21.95% for each index, the index (6) in 17.07% and the index (8) in 9.76%. The three grades of intraepithelial neoplasia proposed by the WHO since 2003 are also found in Lubumbashi patients in varying proportions with no statistically significant difference; 48.78% for grade 3; 36.59% for grade 2 and 14.63% for grade 1. There is no relationship between the HPV infection index and the grade of cervical intraepithelial neoplasia; calculated linear correlation r ^ 2 is equal to 0.00.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients
AU  - Mwenze Didier
AU  - Kyabu Veronique
AU  - Mukalay Abdon
AU  - Kalenga Prosper
AU  - Ilunga Julien
Y1  - 2019/09/18
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcocr.20190403.11
DO  - 10.11648/j.ijcocr.20190403.11
T2  - International Journal of Clinical Oncology and Cancer Research
JF  - International Journal of Clinical Oncology and Cancer Research
JO  - International Journal of Clinical Oncology and Cancer Research
SP  - 29
EP  - 33
PB  - Science Publishing Group
SN  - 2578-9511
UR  - https://doi.org/10.11648/j.ijcocr.20190403.11
AB  - The aim of this study is to show the relationship between the index of Papillomavirus infection and the grade of cervical intraepithelial neoplasia as proposed by WHO in Lubumbashi patients. This is a cross-sectional analytical study on cervical biopsies whose histological diagnosis is an intraepithelial neoplasia registered in two Laboratory of Patholoy in Lubumbashi for a period of two years from June 2017 to June 2019. The following results were observed: A total of 41 cases of intraepithelial neoplasia were recorded out of 91 cervical biopsies is 43.2%. Five indices of Human Papillomavirus infection are found in Lubumbashi patients in variable proportions without statistically significant difference; that is the index (5) in 29.27%, the indices (7) and (9) in 21.95% for each index, the index (6) in 17.07% and the index (8) in 9.76%. The three grades of intraepithelial neoplasia proposed by the WHO since 2003 are also found in Lubumbashi patients in varying proportions with no statistically significant difference; 48.78% for grade 3; 36.59% for grade 2 and 14.63% for grade 1. There is no relationship between the HPV infection index and the grade of cervical intraepithelial neoplasia; calculated linear correlation r ^ 2 is equal to 0.00.
VL  - 4
IS  - 3
ER  -

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