Smooth muscle tumors of the uterus are typically benign, but a rare subset known as smooth muscle tumors of uncertain malignant potential (STUMP) poses diagnostic challenges. First classified by the World Health Organization in 2003 due to their atypical histological features, STUMPs are difficult to distinguish from benign leiomyomas and malignant leiomyosarcomas. This case study describes a 53-year-old woman with a large abdomino-pelvic mass, initially suspected to be sarcoma. Clinical and imaging evaluations, including MRI, led to exploratory laparotomy, revealing a subserosal myoma associated with STUMP. Histopathological analysis confirmed the diagnosis, underscoring the complexities in differentiating STUMPs from other uterine tumors. STUMPs account for a portion of uterine sarcomas, and accurate diagnosis relies on specific histological criteria, including nuclear atypia, mitosis index, and tumor necrosis. Advanced imaging, such as dynamic MRI, helps improve differentiation between STUMP, leiomyosarcoma, and leiomyoma. Although STUMPs are rare, they typically have a better prognosis than leiomyosarcomas, with lower recurrence rates. However, due to their uncertain behavior, patients require long-term monitoring. The limited understanding of STUMPs highlights the need for continued research and clinical vigilance to improve diagnosis and management strategies.
| Published in | International Journal of Clinical Oncology and Cancer Research (Volume 9, Issue 4) |
| DOI | 10.11648/j.ijcocr.20240904.11 |
| Page(s) | 52-56 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
STUMP, Leiomyomas, Leiomyosarcomas
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APA Style
Lamrani, M., Lakhdar, K., Sardaoui, O., Alami, Y., Tijami, F., et al. (2024). Subserosal Myoma Associated with Stump (Smooth Muscle Tumors of Uncertain Malignancy Potential): A Case Report. International Journal of Clinical Oncology and Cancer Research, 9(4), 52-56. https://doi.org/10.11648/j.ijcocr.20240904.11
ACS Style
Lamrani, M.; Lakhdar, K.; Sardaoui, O.; Alami, Y.; Tijami, F., et al. Subserosal Myoma Associated with Stump (Smooth Muscle Tumors of Uncertain Malignancy Potential): A Case Report. Int. J. Clin. Oncol. Cancer Res. 2024, 9(4), 52-56. doi: 10.11648/j.ijcocr.20240904.11
AMA Style
Lamrani M, Lakhdar K, Sardaoui O, Alami Y, Tijami F, et al. Subserosal Myoma Associated with Stump (Smooth Muscle Tumors of Uncertain Malignancy Potential): A Case Report. Int J Clin Oncol Cancer Res. 2024;9(4):52-56. doi: 10.11648/j.ijcocr.20240904.11
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Download@article{10.11648/j.ijcocr.20240904.11,
author = {Meryem Lamrani and Khaoula Lakhdar and Oumaima Sardaoui and Yacir Alami and Fouad Tijami and Hafid Hachi and Zaki El Hanchi and Aziz Baydada},
title = {Subserosal Myoma Associated with Stump (Smooth Muscle Tumors of Uncertain Malignancy Potential): A Case Report
},
journal = {International Journal of Clinical Oncology and Cancer Research},
volume = {9},
number = {4},
pages = {52-56},
doi = {10.11648/j.ijcocr.20240904.11},
url = {https://doi.org/10.11648/j.ijcocr.20240904.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20240904.11},
abstract = {Smooth muscle tumors of the uterus are typically benign, but a rare subset known as smooth muscle tumors of uncertain malignant potential (STUMP) poses diagnostic challenges. First classified by the World Health Organization in 2003 due to their atypical histological features, STUMPs are difficult to distinguish from benign leiomyomas and malignant leiomyosarcomas. This case study describes a 53-year-old woman with a large abdomino-pelvic mass, initially suspected to be sarcoma. Clinical and imaging evaluations, including MRI, led to exploratory laparotomy, revealing a subserosal myoma associated with STUMP. Histopathological analysis confirmed the diagnosis, underscoring the complexities in differentiating STUMPs from other uterine tumors. STUMPs account for a portion of uterine sarcomas, and accurate diagnosis relies on specific histological criteria, including nuclear atypia, mitosis index, and tumor necrosis. Advanced imaging, such as dynamic MRI, helps improve differentiation between STUMP, leiomyosarcoma, and leiomyoma. Although STUMPs are rare, they typically have a better prognosis than leiomyosarcomas, with lower recurrence rates. However, due to their uncertain behavior, patients require long-term monitoring. The limited understanding of STUMPs highlights the need for continued research and clinical vigilance to improve diagnosis and management strategies.
},
year = {2024}
}
TY - JOUR T1 - Subserosal Myoma Associated with Stump (Smooth Muscle Tumors of Uncertain Malignancy Potential): A Case Report AU - Meryem Lamrani AU - Khaoula Lakhdar AU - Oumaima Sardaoui AU - Yacir Alami AU - Fouad Tijami AU - Hafid Hachi AU - Zaki El Hanchi AU - Aziz Baydada Y1 - 2024/11/29 PY - 2024 N1 - https://doi.org/10.11648/j.ijcocr.20240904.11 DO - 10.11648/j.ijcocr.20240904.11 T2 - International Journal of Clinical Oncology and Cancer Research JF - International Journal of Clinical Oncology and Cancer Research JO - International Journal of Clinical Oncology and Cancer Research SP - 52 EP - 56 PB - Science Publishing Group SN - 2578-9511 UR - https://doi.org/10.11648/j.ijcocr.20240904.11 AB - Smooth muscle tumors of the uterus are typically benign, but a rare subset known as smooth muscle tumors of uncertain malignant potential (STUMP) poses diagnostic challenges. First classified by the World Health Organization in 2003 due to their atypical histological features, STUMPs are difficult to distinguish from benign leiomyomas and malignant leiomyosarcomas. This case study describes a 53-year-old woman with a large abdomino-pelvic mass, initially suspected to be sarcoma. Clinical and imaging evaluations, including MRI, led to exploratory laparotomy, revealing a subserosal myoma associated with STUMP. Histopathological analysis confirmed the diagnosis, underscoring the complexities in differentiating STUMPs from other uterine tumors. STUMPs account for a portion of uterine sarcomas, and accurate diagnosis relies on specific histological criteria, including nuclear atypia, mitosis index, and tumor necrosis. Advanced imaging, such as dynamic MRI, helps improve differentiation between STUMP, leiomyosarcoma, and leiomyoma. Although STUMPs are rare, they typically have a better prognosis than leiomyosarcomas, with lower recurrence rates. However, due to their uncertain behavior, patients require long-term monitoring. The limited understanding of STUMPs highlights the need for continued research and clinical vigilance to improve diagnosis and management strategies. VL - 9 IS - 4 ER -
Department of Gynecology-Obstetrics and Endoscopy, University Hospital Center Ibn Sina of Rabat, Mohammed 5 of Rabat University, Rabat, Morocco
Department of Gynecology-Obstetrics and Endoscopy, University Hospital Center Ibn Sina of Rabat, Mohammed 5 of Rabat University, Rabat, Morocco
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