The extramedullary plasmacytomas is a plasma cell tumour arising outside the bone marrow and constitutes around 4 % of all plasma cell neoplasms. The Extramedullary Plasmacytoma of the Trachea (EPT) is an extremely rare condition and presents as a tracheal expanding mass. The most common symptoms consist of coughing, dyspnoea, voice change, stridor and expiratory wheezing. The diagnosis is done by computed tomography, bronchoscopy and histological examination which demonstrates neoplastic monoclonal plasma cells expressing specific antigens. The treatment of the EPT remains still speculative, current options are radiotherapy or surgery alone and surgery followed by radiotherapy. The adjuvant chemotherapy is considered only in case of relapse or systemic spread. The prognosis is comforting: the complete remission occurs in 60 % of cases, the recurrence in 22 %, the progression to multiple myeloma in 16 %. We report the case of a 51-year-old female affected by EPT and treated with the removal of the first four tracheal rings and subsequent PAD chemotherapy (bortezomib, adriamycin and dexamethasone). Although the stage of the tumour was early, we decided to administer chemotherapy conceiving it as a preventive systemic treatment.
| Published in | International Journal of Cardiovascular and Thoracic Surgery (Volume 2, Issue 1) |
| DOI | 10.11648/j.ijcts.20160201.12 |
| Page(s) | 5-8 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2016. Published by Science Publishing Group |
Tracheal Tumours, Tracheal Resection, Extramedullary Plasmacytoma, Airway Obstruction
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APA Style
Antonello Cuttitta, Antonio Tancredi, Roberto Scaramuzzi, Antonietta Falcone, Gerardo Scaramuzzi, et al. (2016). Solitary Extramedullary Plasmacytoma of the Trachea: A Case Report. International Journal of Cardiovascular and Thoracic Surgery, 2(1), 5-8. https://doi.org/10.11648/j.ijcts.20160201.12
ACS Style
Antonello Cuttitta; Antonio Tancredi; Roberto Scaramuzzi; Antonietta Falcone; Gerardo Scaramuzzi, et al. Solitary Extramedullary Plasmacytoma of the Trachea: A Case Report. Int. J. Cardiovasc. Thorac. Surg. 2016, 2(1), 5-8. doi: 10.11648/j.ijcts.20160201.12
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Download@article{10.11648/j.ijcts.20160201.12,
author = {Antonello Cuttitta and Antonio Tancredi and Roberto Scaramuzzi and Antonietta Falcone and Gerardo Scaramuzzi and Marco Taurchini},
title = {Solitary Extramedullary Plasmacytoma of the Trachea: A Case Report},
journal = {International Journal of Cardiovascular and Thoracic Surgery},
volume = {2},
number = {1},
pages = {5-8},
doi = {10.11648/j.ijcts.20160201.12},
url = {https://doi.org/10.11648/j.ijcts.20160201.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcts.20160201.12},
abstract = {The extramedullary plasmacytomas is a plasma cell tumour arising outside the bone marrow and constitutes around 4 % of all plasma cell neoplasms. The Extramedullary Plasmacytoma of the Trachea (EPT) is an extremely rare condition and presents as a tracheal expanding mass. The most common symptoms consist of coughing, dyspnoea, voice change, stridor and expiratory wheezing. The diagnosis is done by computed tomography, bronchoscopy and histological examination which demonstrates neoplastic monoclonal plasma cells expressing specific antigens. The treatment of the EPT remains still speculative, current options are radiotherapy or surgery alone and surgery followed by radiotherapy. The adjuvant chemotherapy is considered only in case of relapse or systemic spread. The prognosis is comforting: the complete remission occurs in 60 % of cases, the recurrence in 22 %, the progression to multiple myeloma in 16 %. We report the case of a 51-year-old female affected by EPT and treated with the removal of the first four tracheal rings and subsequent PAD chemotherapy (bortezomib, adriamycin and dexamethasone). Although the stage of the tumour was early, we decided to administer chemotherapy conceiving it as a preventive systemic treatment.},
year = {2016}
}
TY - JOUR T1 - Solitary Extramedullary Plasmacytoma of the Trachea: A Case Report AU - Antonello Cuttitta AU - Antonio Tancredi AU - Roberto Scaramuzzi AU - Antonietta Falcone AU - Gerardo Scaramuzzi AU - Marco Taurchini Y1 - 2016/05/05 PY - 2016 N1 - https://doi.org/10.11648/j.ijcts.20160201.12 DO - 10.11648/j.ijcts.20160201.12 T2 - International Journal of Cardiovascular and Thoracic Surgery JF - International Journal of Cardiovascular and Thoracic Surgery JO - International Journal of Cardiovascular and Thoracic Surgery SP - 5 EP - 8 PB - Science Publishing Group SN - 2575-4882 UR - https://doi.org/10.11648/j.ijcts.20160201.12 AB - The extramedullary plasmacytomas is a plasma cell tumour arising outside the bone marrow and constitutes around 4 % of all plasma cell neoplasms. The Extramedullary Plasmacytoma of the Trachea (EPT) is an extremely rare condition and presents as a tracheal expanding mass. The most common symptoms consist of coughing, dyspnoea, voice change, stridor and expiratory wheezing. The diagnosis is done by computed tomography, bronchoscopy and histological examination which demonstrates neoplastic monoclonal plasma cells expressing specific antigens. The treatment of the EPT remains still speculative, current options are radiotherapy or surgery alone and surgery followed by radiotherapy. The adjuvant chemotherapy is considered only in case of relapse or systemic spread. The prognosis is comforting: the complete remission occurs in 60 % of cases, the recurrence in 22 %, the progression to multiple myeloma in 16 %. We report the case of a 51-year-old female affected by EPT and treated with the removal of the first four tracheal rings and subsequent PAD chemotherapy (bortezomib, adriamycin and dexamethasone). Although the stage of the tumour was early, we decided to administer chemotherapy conceiving it as a preventive systemic treatment. VL - 2 IS - 1 ER -
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