This study compares post-operative outcomes for ionotropic support, defibrillator need and duration of hospital stay in adult patients of cardiac surgery following Del Nido cardioplegia versus Howard’s cardioplegia and also compare pre and post operative Cardiac enzymes and serum potassium levels, assessment of pre and post operative Arrthymias. It was an Observational study conducted at Pakistan Institute of Medical Sciences Islamabad Pakistan. Patients were divided into 2 groups. Group (A) patients were Del Nido cardioplegia and Group (B) patients were Howard’s cardioplegia. Data was collected by using non-probability Consecutive Sampling technique. 100 patients were enrolled in this study randomly allocating 50 to each study group. Results of the study show that Post-op CKMB level after 24 hours for Howard group was (127.5200±103.59069) and for DN group (67.3540±23.21292). Similarly post op Potassium level for Howard group was (4.9742±.77010) and for DN group was (4.5590±.65033), Duration of hospital stay for Howard’s group was (9.60±.857) and for DN group was (8.58±1.486). High ionotropic support was required in Howard’s group as compared to DN where it was mild to moderate. 40% patients required defibrillation in Howards as compared to DN with only 20%. It is concluded that Cardioplegia is intended for brief cardiac arrest, which is an important function during cardiopulmonary Bypass surgery. After comparing two cardioplegic solutions namely Del Nido and Howard’s cardioplegia. Our study concludes that Del-Nido cardioplegia provide better myocardial protection and less cross clamp and bypass time. Cardiac enzymes, serum potassium level and post-op arrthymias show better profile in Del-Nido as compared to Howard’s cardiolpegia. Our data clearly advocate the efficacy and safety of Del-Nido over Howard’s cardioplegia. It is very safe and effective as compared to Howards.
| Published in | International Journal of Cardiovascular and Thoracic Surgery (Volume 6, Issue 1) |
| DOI | 10.11648/j.ijcts.20200601.11 |
| Page(s) | 1-6 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
Cardiopulmonary Bypass, Coronary Artery Disease, Adult Cardiac Surgery, Cardioplegia, Howards, Del-Nido, Cardiac Enzymes
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APA Style
Adnan Shah, Attiya Hameed Khan, Hammad Ahmed, Aamir Naveed, Faridullah Khan, et al. (2020). Comparison of Post Operative Outcomes Following Del Nido Cardioplegia Versus Howards Cardioplegia in Adult Cardiac Surgery at Pakistan Institute of Medical Sciences. International Journal of Cardiovascular and Thoracic Surgery, 6(1), 1-6. https://doi.org/10.11648/j.ijcts.20200601.11
ACS Style
Adnan Shah; Attiya Hameed Khan; Hammad Ahmed; Aamir Naveed; Faridullah Khan, et al. Comparison of Post Operative Outcomes Following Del Nido Cardioplegia Versus Howards Cardioplegia in Adult Cardiac Surgery at Pakistan Institute of Medical Sciences. Int. J. Cardiovasc. Thorac. Surg. 2020, 6(1), 1-6. doi: 10.11648/j.ijcts.20200601.11
AMA Style
Adnan Shah, Attiya Hameed Khan, Hammad Ahmed, Aamir Naveed, Faridullah Khan, et al. Comparison of Post Operative Outcomes Following Del Nido Cardioplegia Versus Howards Cardioplegia in Adult Cardiac Surgery at Pakistan Institute of Medical Sciences. Int J Cardiovasc Thorac Surg. 2020;6(1):1-6. doi: 10.11648/j.ijcts.20200601.11
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Download@article{10.11648/j.ijcts.20200601.11,
author = {Adnan Shah and Attiya Hameed Khan and Hammad Ahmed and Aamir Naveed and Faridullah Khan and Javeed Iqbal and Adnan Tahir},
title = {Comparison of Post Operative Outcomes Following Del Nido Cardioplegia Versus Howards Cardioplegia in Adult Cardiac Surgery at Pakistan Institute of Medical Sciences},
journal = {International Journal of Cardiovascular and Thoracic Surgery},
volume = {6},
number = {1},
pages = {1-6},
doi = {10.11648/j.ijcts.20200601.11},
url = {https://doi.org/10.11648/j.ijcts.20200601.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcts.20200601.11},
abstract = {This study compares post-operative outcomes for ionotropic support, defibrillator need and duration of hospital stay in adult patients of cardiac surgery following Del Nido cardioplegia versus Howard’s cardioplegia and also compare pre and post operative Cardiac enzymes and serum potassium levels, assessment of pre and post operative Arrthymias. It was an Observational study conducted at Pakistan Institute of Medical Sciences Islamabad Pakistan. Patients were divided into 2 groups. Group (A) patients were Del Nido cardioplegia and Group (B) patients were Howard’s cardioplegia. Data was collected by using non-probability Consecutive Sampling technique. 100 patients were enrolled in this study randomly allocating 50 to each study group. Results of the study show that Post-op CKMB level after 24 hours for Howard group was (127.5200±103.59069) and for DN group (67.3540±23.21292). Similarly post op Potassium level for Howard group was (4.9742±.77010) and for DN group was (4.5590±.65033), Duration of hospital stay for Howard’s group was (9.60±.857) and for DN group was (8.58±1.486). High ionotropic support was required in Howard’s group as compared to DN where it was mild to moderate. 40% patients required defibrillation in Howards as compared to DN with only 20%. It is concluded that Cardioplegia is intended for brief cardiac arrest, which is an important function during cardiopulmonary Bypass surgery. After comparing two cardioplegic solutions namely Del Nido and Howard’s cardioplegia. Our study concludes that Del-Nido cardioplegia provide better myocardial protection and less cross clamp and bypass time. Cardiac enzymes, serum potassium level and post-op arrthymias show better profile in Del-Nido as compared to Howard’s cardiolpegia. Our data clearly advocate the efficacy and safety of Del-Nido over Howard’s cardioplegia. It is very safe and effective as compared to Howards.},
year = {2020}
}
TY - JOUR T1 - Comparison of Post Operative Outcomes Following Del Nido Cardioplegia Versus Howards Cardioplegia in Adult Cardiac Surgery at Pakistan Institute of Medical Sciences AU - Adnan Shah AU - Attiya Hameed Khan AU - Hammad Ahmed AU - Aamir Naveed AU - Faridullah Khan AU - Javeed Iqbal AU - Adnan Tahir Y1 - 2020/02/04 PY - 2020 N1 - https://doi.org/10.11648/j.ijcts.20200601.11 DO - 10.11648/j.ijcts.20200601.11 T2 - International Journal of Cardiovascular and Thoracic Surgery JF - International Journal of Cardiovascular and Thoracic Surgery JO - International Journal of Cardiovascular and Thoracic Surgery SP - 1 EP - 6 PB - Science Publishing Group SN - 2575-4882 UR - https://doi.org/10.11648/j.ijcts.20200601.11 AB - This study compares post-operative outcomes for ionotropic support, defibrillator need and duration of hospital stay in adult patients of cardiac surgery following Del Nido cardioplegia versus Howard’s cardioplegia and also compare pre and post operative Cardiac enzymes and serum potassium levels, assessment of pre and post operative Arrthymias. It was an Observational study conducted at Pakistan Institute of Medical Sciences Islamabad Pakistan. Patients were divided into 2 groups. Group (A) patients were Del Nido cardioplegia and Group (B) patients were Howard’s cardioplegia. Data was collected by using non-probability Consecutive Sampling technique. 100 patients were enrolled in this study randomly allocating 50 to each study group. Results of the study show that Post-op CKMB level after 24 hours for Howard group was (127.5200±103.59069) and for DN group (67.3540±23.21292). Similarly post op Potassium level for Howard group was (4.9742±.77010) and for DN group was (4.5590±.65033), Duration of hospital stay for Howard’s group was (9.60±.857) and for DN group was (8.58±1.486). High ionotropic support was required in Howard’s group as compared to DN where it was mild to moderate. 40% patients required defibrillation in Howards as compared to DN with only 20%. It is concluded that Cardioplegia is intended for brief cardiac arrest, which is an important function during cardiopulmonary Bypass surgery. After comparing two cardioplegic solutions namely Del Nido and Howard’s cardioplegia. Our study concludes that Del-Nido cardioplegia provide better myocardial protection and less cross clamp and bypass time. Cardiac enzymes, serum potassium level and post-op arrthymias show better profile in Del-Nido as compared to Howard’s cardiolpegia. Our data clearly advocate the efficacy and safety of Del-Nido over Howard’s cardioplegia. It is very safe and effective as compared to Howards. VL - 6 IS - 1 ER -
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