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Primary Sjӧgren’s Syndrome and Oral Cavity Disorders

Received: 27 November 2017     Accepted: 11 December 2017     Published: 8 January 2018
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Abstract

Sjögren’s Syndrome (SS) is one of the three most common autoimmune diseases in the world, which affects the exocrine glands, specifically the salivary and lacrimal glands. Primary SS (pSS) particularly affects only the exocrine glands, while secondary SS is associated with other systemic autoimmune pathologies. SS is characterized, histopathologically, by an inflammatory lymphocytic infiltrate that interferes with the normal gland function. It affects 0, 5% of the world population, being more common in women (9:1 versus men), mainly around 50 years old, after the menopause. The medical dentist role is very important in the diagnosis of pSS, as in most cases he is the one who detects the first symptoms, in particular dry mouth or xerostomia. The primary syndrome doesn’t have a painful development, being dry mouth and eye dryness the most prominent clinical characteristics. The majority of the oral evidences are consequence of salivary glands hypofunction: dental caries, periodontal disease or fungal infections. Along with hyposalivation and xerostomia communication disorders can occur like dysphagia and pharyngeal dryness leading to difficulties in speech and voice fatigue. These last ones have a negative impact in the patients quality of life although a large percentage don’t seek professional help. There is a need for awareness of the voice disorders associate with pSS referring the patients to proper professional help. The treatment of pSS is empirical, symptomatic and aimed at dealing with the complications during the early-stages of the disease consisting of limiting the xerostomia and xerophthalmia damages.

Published in International Journal of Dental Medicine (Volume 3, Issue 5)
DOI 10.11648/j.ijdm.20170305.11
Page(s) 20-26
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Primary Sjögren’s Syndrome, Pathogenesis, Voice Disorders, Dysphagia, Oral Infections, Xerostomia

References
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Cite This Article
  • APA Style

    Soares Sandra Clara, Chapela Sara Cendon. (2018). Primary Sjӧgren’s Syndrome and Oral Cavity Disorders. International Journal of Dental Medicine, 3(5), 20-26. https://doi.org/10.11648/j.ijdm.20170305.11

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    ACS Style

    Soares Sandra Clara; Chapela Sara Cendon. Primary Sjӧgren’s Syndrome and Oral Cavity Disorders. Int. J. Dent. Med. 2018, 3(5), 20-26. doi: 10.11648/j.ijdm.20170305.11

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    AMA Style

    Soares Sandra Clara, Chapela Sara Cendon. Primary Sjӧgren’s Syndrome and Oral Cavity Disorders. Int J Dent Med. 2018;3(5):20-26. doi: 10.11648/j.ijdm.20170305.11

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  • @article{10.11648/j.ijdm.20170305.11,
      author = {Soares Sandra Clara and Chapela Sara Cendon},
      title = {Primary Sjӧgren’s Syndrome and Oral Cavity Disorders},
      journal = {International Journal of Dental Medicine},
      volume = {3},
      number = {5},
      pages = {20-26},
      doi = {10.11648/j.ijdm.20170305.11},
      url = {https://doi.org/10.11648/j.ijdm.20170305.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijdm.20170305.11},
      abstract = {Sjögren’s Syndrome (SS) is one of the three most common autoimmune diseases in the world, which affects the exocrine glands, specifically the salivary and lacrimal glands. Primary SS (pSS) particularly affects only the exocrine glands, while secondary SS is associated with other systemic autoimmune pathologies. SS is characterized, histopathologically, by an inflammatory lymphocytic infiltrate that interferes with the normal gland function. It affects 0, 5% of the world population, being more common in women (9:1 versus men), mainly around 50 years old, after the menopause. The medical dentist role is very important in the diagnosis of pSS, as in most cases he is the one who detects the first symptoms, in particular dry mouth or xerostomia. The primary syndrome doesn’t have a painful development, being dry mouth and eye dryness the most prominent clinical characteristics. The majority of the oral evidences are consequence of salivary glands hypofunction: dental caries, periodontal disease or fungal infections. Along with hyposalivation and xerostomia communication disorders can occur like dysphagia and pharyngeal dryness leading to difficulties in speech and voice fatigue. These last ones have a negative impact in the patients quality of life although a large percentage don’t seek professional help. There is a need for awareness of the voice disorders associate with pSS referring the patients to proper professional help. The treatment of pSS is empirical, symptomatic and aimed at dealing with the complications during the early-stages of the disease consisting of limiting the xerostomia and xerophthalmia damages.},
     year = {2018}
    }
    

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    AU  - Soares Sandra Clara
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    Y1  - 2018/01/08
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    T2  - International Journal of Dental Medicine
    JF  - International Journal of Dental Medicine
    JO  - International Journal of Dental Medicine
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    AB  - Sjögren’s Syndrome (SS) is one of the three most common autoimmune diseases in the world, which affects the exocrine glands, specifically the salivary and lacrimal glands. Primary SS (pSS) particularly affects only the exocrine glands, while secondary SS is associated with other systemic autoimmune pathologies. SS is characterized, histopathologically, by an inflammatory lymphocytic infiltrate that interferes with the normal gland function. It affects 0, 5% of the world population, being more common in women (9:1 versus men), mainly around 50 years old, after the menopause. The medical dentist role is very important in the diagnosis of pSS, as in most cases he is the one who detects the first symptoms, in particular dry mouth or xerostomia. The primary syndrome doesn’t have a painful development, being dry mouth and eye dryness the most prominent clinical characteristics. The majority of the oral evidences are consequence of salivary glands hypofunction: dental caries, periodontal disease or fungal infections. Along with hyposalivation and xerostomia communication disorders can occur like dysphagia and pharyngeal dryness leading to difficulties in speech and voice fatigue. These last ones have a negative impact in the patients quality of life although a large percentage don’t seek professional help. There is a need for awareness of the voice disorders associate with pSS referring the patients to proper professional help. The treatment of pSS is empirical, symptomatic and aimed at dealing with the complications during the early-stages of the disease consisting of limiting the xerostomia and xerophthalmia damages.
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Author Information
  • Fernando Pessoa Energy, Environment and Health Research Unite/Biomedical Research Center (FP-ENAS/CEBIMED), Faculty of Health Sciences, Fernando Pessoa University, Porto, Portugal

  • Clinica Dental Paula González Chapela, Vigo, Spain

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