Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis

Wanyun Lin; Chen Xie; Chunyi Cao; Shengping Cao; Xiaoting Li; Tingting Li; Yujia Zhai; Jingni Guo; Vannesa Bongani Muyeleka; Zhuling Guo

doi:doi:10.11648/j.ijdm.20210701.12

Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis

Wanyun Lin, Chen Xie, Chunyi Cao, Shengping Cao, Xiaoting Li, Tingting Li, Yujia Zhai, Jingni Guo, Vannesa Bongani Muyeleka, Zhuling Guo

Published in International Journal of Dental Medicine (Volume 7, Issue 1)

Received: 28 April 2021 Accepted: 17 May 2021 Published: 27 May 2021

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Abstract

Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.

Published in	International Journal of Dental Medicine (Volume 7, Issue 1)
DOI	10.11648/j.ijdm.20210701.12
Page(s)	10-14
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Diabetes Mellitus, Implant, Peri-Implantitis, Osseointegration

References

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APA Style

Wanyun Lin, Chen Xie, Chunyi Cao, Shengping Cao, Xiaoting Li, et al. (2021). Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. International Journal of Dental Medicine, 7(1), 10-14. https://doi.org/10.11648/j.ijdm.20210701.12

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ACS Style

Wanyun Lin; Chen Xie; Chunyi Cao; Shengping Cao; Xiaoting Li, et al. Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. Int. J. Dent. Med. 2021, 7(1), 10-14. doi: 10.11648/j.ijdm.20210701.12

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AMA Style

Wanyun Lin, Chen Xie, Chunyi Cao, Shengping Cao, Xiaoting Li, et al. Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. Int J Dent Med. 2021;7(1):10-14. doi: 10.11648/j.ijdm.20210701.12

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@article{10.11648/j.ijdm.20210701.12,
  author = {Wanyun Lin and Chen Xie and Chunyi Cao and Shengping Cao and Xiaoting Li and Tingting Li and Yujia Zhai and Jingni Guo and Vannesa Bongani Muyeleka and Zhuling Guo},
  title = {Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis},
  journal = {International Journal of Dental Medicine},
  volume = {7},
  number = {1},
  pages = {10-14},
  doi = {10.11648/j.ijdm.20210701.12},
  url = {https://doi.org/10.11648/j.ijdm.20210701.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijdm.20210701.12},
  abstract = {Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.},
 year = {2021}
}

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TY  - JOUR
T1  - Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis
AU  - Wanyun Lin
AU  - Chen Xie
AU  - Chunyi Cao
AU  - Shengping Cao
AU  - Xiaoting Li
AU  - Tingting Li
AU  - Yujia Zhai
AU  - Jingni Guo
AU  - Vannesa Bongani Muyeleka
AU  - Zhuling Guo
Y1  - 2021/05/27
PY  - 2021
N1  - https://doi.org/10.11648/j.ijdm.20210701.12
DO  - 10.11648/j.ijdm.20210701.12
T2  - International Journal of Dental Medicine
JF  - International Journal of Dental Medicine
JO  - International Journal of Dental Medicine
SP  - 10
EP  - 14
PB  - Science Publishing Group
SN  - 2472-1387
UR  - https://doi.org/10.11648/j.ijdm.20210701.12
AB  - Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.
VL  - 7
IS  - 1
ER  -

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Author Information

Wanyun Lin

School of Dentistry, Hainan Medical University, Haikou, PR China
Chen Xie

School of Dentistry, Hainan Medical University, Haikou, PR China
Chunyi Cao

2Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, PR China
Shengping Cao

School of Clinical Medicine, Hainan Medical University, Haikou, PR China
Xiaoting Li

Department of Dentistry, the First Affiliated Hospital of Hainan Medical University, Haikou, PR China
Tingting Li

School of Clinical Medicine, Hainan Medical University, Haikou, PR China
Yujia Zhai

School of Clinical Medicine, Hainan Medical University, Haikou, PR China
Jingni Guo

School of Dentistry, Hainan Medical University, Haikou, PR China
Vannesa Bongani Muyeleka

School of Clinical Medicine, Hainan Medical University, Haikou, PR China
Zhuling Guo

School of Dentistry, Hainan Medical University, Haikou, PR China

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APA Style

Wanyun Lin, Chen Xie, Chunyi Cao, Shengping Cao, Xiaoting Li, et al. (2021). Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. International Journal of Dental Medicine, 7(1), 10-14. https://doi.org/10.11648/j.ijdm.20210701.12

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ACS Style

Wanyun Lin; Chen Xie; Chunyi Cao; Shengping Cao; Xiaoting Li, et al. Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. Int. J. Dent. Med. 2021, 7(1), 10-14. doi: 10.11648/j.ijdm.20210701.12

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AMA Style

Wanyun Lin, Chen Xie, Chunyi Cao, Shengping Cao, Xiaoting Li, et al. Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. Int J Dent Med. 2021;7(1):10-14. doi: 10.11648/j.ijdm.20210701.12

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@article{10.11648/j.ijdm.20210701.12,
  author = {Wanyun Lin and Chen Xie and Chunyi Cao and Shengping Cao and Xiaoting Li and Tingting Li and Yujia Zhai and Jingni Guo and Vannesa Bongani Muyeleka and Zhuling Guo},
  title = {Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis},
  journal = {International Journal of Dental Medicine},
  volume = {7},
  number = {1},
  pages = {10-14},
  doi = {10.11648/j.ijdm.20210701.12},
  url = {https://doi.org/10.11648/j.ijdm.20210701.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijdm.20210701.12},
  abstract = {Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis
AU  - Wanyun Lin
AU  - Chen Xie
AU  - Chunyi Cao
AU  - Shengping Cao
AU  - Xiaoting Li
AU  - Tingting Li
AU  - Yujia Zhai
AU  - Jingni Guo
AU  - Vannesa Bongani Muyeleka
AU  - Zhuling Guo
Y1  - 2021/05/27
PY  - 2021
N1  - https://doi.org/10.11648/j.ijdm.20210701.12
DO  - 10.11648/j.ijdm.20210701.12
T2  - International Journal of Dental Medicine
JF  - International Journal of Dental Medicine
JO  - International Journal of Dental Medicine
SP  - 10
EP  - 14
PB  - Science Publishing Group
SN  - 2472-1387
UR  - https://doi.org/10.11648/j.ijdm.20210701.12
AB  - Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.
VL  - 7
IS  - 1
ER  -

Copy | Download