Adulterated food is a silent killer. Dishonest traders used textile dyes as adulterant in different foods as unethical practices. Moreover, textile industries also throw waste dye as effluent in ground water. In this study, we investigated the toxic effects of two textile dyes Coralene Red XF and Remazol Red RR by in vivo experiments in mice. Mice were administered Coralene Red XF and Remazol Red RR textile dyes at a single oral dose of 0.04g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SUR) and histopathology of liver and kidney. The levels of AST, ALT, STBI, SUR and SCR were found to be increased by both Coralene Red XF and Remazol Red RR. Histopathological examination of liver showed inflammatory atypia of hepatocytes and inflamation also observed in kidney.
Published in | International Journal of Food Science and Biotechnology (Volume 2, Issue 3) |
DOI | 10.11648/j.ijfsb.20170203.14 |
Page(s) | 97-102 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
In vivo, Textile Dyes, Coralene Red XF, Remazol Red RR, Toxicity
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APA Style
Mohammad Farhadur Rahman, Nargish Jahan Ara, Bishnu Pada Dey, Mohammad Zakir Sultan. (2017). Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice. International Journal of Food Science and Biotechnology, 2(3), 97-102. https://doi.org/10.11648/j.ijfsb.20170203.14
ACS Style
Mohammad Farhadur Rahman; Nargish Jahan Ara; Bishnu Pada Dey; Mohammad Zakir Sultan. Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice. Int. J. Food Sci. Biotechnol. 2017, 2(3), 97-102. doi: 10.11648/j.ijfsb.20170203.14
@article{10.11648/j.ijfsb.20170203.14, author = {Mohammad Farhadur Rahman and Nargish Jahan Ara and Bishnu Pada Dey and Mohammad Zakir Sultan}, title = {Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice}, journal = {International Journal of Food Science and Biotechnology}, volume = {2}, number = {3}, pages = {97-102}, doi = {10.11648/j.ijfsb.20170203.14}, url = {https://doi.org/10.11648/j.ijfsb.20170203.14}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijfsb.20170203.14}, abstract = {Adulterated food is a silent killer. Dishonest traders used textile dyes as adulterant in different foods as unethical practices. Moreover, textile industries also throw waste dye as effluent in ground water. In this study, we investigated the toxic effects of two textile dyes Coralene Red XF and Remazol Red RR by in vivo experiments in mice. Mice were administered Coralene Red XF and Remazol Red RR textile dyes at a single oral dose of 0.04g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SUR) and histopathology of liver and kidney. The levels of AST, ALT, STBI, SUR and SCR were found to be increased by both Coralene Red XF and Remazol Red RR. Histopathological examination of liver showed inflammatory atypia of hepatocytes and inflamation also observed in kidney.}, year = {2017} }
TY - JOUR T1 - Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice AU - Mohammad Farhadur Rahman AU - Nargish Jahan Ara AU - Bishnu Pada Dey AU - Mohammad Zakir Sultan Y1 - 2017/07/31 PY - 2017 N1 - https://doi.org/10.11648/j.ijfsb.20170203.14 DO - 10.11648/j.ijfsb.20170203.14 T2 - International Journal of Food Science and Biotechnology JF - International Journal of Food Science and Biotechnology JO - International Journal of Food Science and Biotechnology SP - 97 EP - 102 PB - Science Publishing Group SN - 2578-9643 UR - https://doi.org/10.11648/j.ijfsb.20170203.14 AB - Adulterated food is a silent killer. Dishonest traders used textile dyes as adulterant in different foods as unethical practices. Moreover, textile industries also throw waste dye as effluent in ground water. In this study, we investigated the toxic effects of two textile dyes Coralene Red XF and Remazol Red RR by in vivo experiments in mice. Mice were administered Coralene Red XF and Remazol Red RR textile dyes at a single oral dose of 0.04g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SUR) and histopathology of liver and kidney. The levels of AST, ALT, STBI, SUR and SCR were found to be increased by both Coralene Red XF and Remazol Red RR. Histopathological examination of liver showed inflammatory atypia of hepatocytes and inflamation also observed in kidney. VL - 2 IS - 3 ER -