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Halting the Scourge of HIV in Nigeria by Adopting World Health Organization Guidelines for Preventing New Infections (Policy Brief Paper)

Received: 30 May 2021     Accepted: 15 June 2021     Published: 21 June 2021
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Abstract

Nigeria bears 10% of global HIV burden and contributes 32% to global unmet-need for Prevention of Mother to Child transmission of HIV (PMTCT), which together with heterosexual transmission are the epidemic’s key drivers as PMTCT clinics show approximately 45% serodiscordance rates among couples. WHO recommends accelerated Anti-retroviral Therapy initiation for all persons living with HIV (PLHIV) for improved quality-of-life and preventing new vertical and horizontal infections, using same drug – Emtricitabine, Tenofovir and Efaverenz (once daily Atripla). The policy paper seeks to make a case that the National PMTCT task team and the Federal Ministry of health of Nigeria, should make a policy change, and shift from the current Option B PMTCT option. The option provides Antiretroviral drugs (ARVs) to pregnant HIV positive women who do for PMTCT, but discontinue them after cessation of breast-feeding, when the viral load is above 500cells/mm3. It proposes that the country should rather adopt the test and treat all policy for all HIV infected persons. The methodology entails the search and use of literature to demonstrate the multiple advantages of early commencement of treatment for all new of HIV infections, considering this has been shown to reduce morbidity and mortality. The results indicate that test and treat all for life, is now less complex as same drug regimen are used in PMTCT and other non PMTCT adult infections. Studies also show that virologic suppression (undetectable) leads to prevention of new HIV transmission (untransmitable), and this applies to different modes of HIV transmission. The brief concludes by proposing that the Federal Ministry of Health, the National AIDS Control agency, and all actors in Nigeria’s HIV terrains should adopt the WHO test and treat guidelines. This remains a critical step for the elimination of Paediatric HIV infections.

Published in International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 7, Issue 1)
DOI 10.11648/j.ijhpebs.20210701.15
Page(s) 48-53
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Undetectable, Untransmitable, Policy, PMTCT, HIV Transmission, Atripla

References
[1] Federal Ministry of Health, Nigeria (2014). Integrated National Guidelines for HIV Prevention and Care.
[2] UNAIDS (2011). The Global Plan towards the Elimination of New HIV Infections among Children by 2015 and Keeping Their Mothers Alive, 2011-2015.
[3] WHO/UNAIDS. Geneva: 2007. Towards Universal Access ACCESS Scaling up priority HIV/AIDS interventions in the health sector Progress Report.
[4] Sagay AS, Ebonyi OE, Meloni ST, Musa J, Oguche S, Ekwempu CC et al.(2015). Mother-to-Child Transmission Outcomes of HIV-Exposed Infants Followed Up in Jos North-Central Nigeria. Current HIV Research, 2015. Bentham Science Publishers.
[5] Balkus E J, Brown E, Palanee T, Nair G, Gafoor Z, Zhang J, Richardson B A, Chirenje Z M, Marrazzo J M, Baeten J M. (2016). An Empiric HIV Risk Scoring Tool to Predict HIV-1 Acquisition in African Women. AIDS Journal of Acquired Immune Deficiency Syndromes. 2016 Jul 1; 72 (3): 333-43 https://www.ncbi.nlm.nih.gov/pubmed/26918545.
[6] Kahle EM, Hughes JP, Lingappa JR, Johnstewart G, Celum C, et al.(2013) An Empiric Risk Scoring Tool for Identifying High-Risk Heterosexual HIV-1 Serodiscordant Couples for Targeted HIV-1 Prevention. Journal Acquired Immune Deficiency Syndrome.
[7] World Health Organization (2016). Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. 2016 update.
[8] World Health Organization (2016). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach - Second edition. Available at http://www.who.int/hiv/pub/arv/arv-2016/en/.
[9] Federal Ministry of Health, Nigeria (2014). Task-Shifting and Task-sharing Policy for Essential Health Care Services In Nigeria. Available at https://www.health.gov.ng/doc/TSTS.pdf assessed on 01/06 /2021.
[10] Nigeria’s National Agency for the Control of AIDS (2010). The Nigerian National HIV/AIDS Strategic Plan (NSP) 2010-2015. Available at http://www.ilo.org/wcmsp5/groups/public/---ed_protect/---protrav/---ilo_aids/documents/legaldocument/wcms_146389.pdf.
[11] Adult Antiretroviral Therapy Guidelines 2014. The Southern African HIV Clinicians Society. Available at https://sahivsoc.org.
[12] Chatora, M., Chibanda, H., Kampata, L., Wilbroad, M. (2018). HIV/AIDS workplace policy addressing epidemic drivers through workplace programs. BMC Public Health 18, 180 (2018). https://doi.org/10.1186/s12889-018-5072-y.
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    Tinuade Abimbola Oyebode, Martha Ochoga, Yetunde Tagurum, Solomon Atiene Sagay. (2021). Halting the Scourge of HIV in Nigeria by Adopting World Health Organization Guidelines for Preventing New Infections (Policy Brief Paper). International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 7(1), 48-53. https://doi.org/10.11648/j.ijhpebs.20210701.15

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    ACS Style

    Tinuade Abimbola Oyebode; Martha Ochoga; Yetunde Tagurum; Solomon Atiene Sagay. Halting the Scourge of HIV in Nigeria by Adopting World Health Organization Guidelines for Preventing New Infections (Policy Brief Paper). Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2021, 7(1), 48-53. doi: 10.11648/j.ijhpebs.20210701.15

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    AMA Style

    Tinuade Abimbola Oyebode, Martha Ochoga, Yetunde Tagurum, Solomon Atiene Sagay. Halting the Scourge of HIV in Nigeria by Adopting World Health Organization Guidelines for Preventing New Infections (Policy Brief Paper). Int J HIV/AIDS Prev Educ Behav Sci. 2021;7(1):48-53. doi: 10.11648/j.ijhpebs.20210701.15

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  • @article{10.11648/j.ijhpebs.20210701.15,
      author = {Tinuade Abimbola Oyebode and Martha Ochoga and Yetunde Tagurum and Solomon Atiene Sagay},
      title = {Halting the Scourge of HIV in Nigeria by Adopting World Health Organization Guidelines for Preventing New Infections (Policy Brief Paper)},
      journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
      volume = {7},
      number = {1},
      pages = {48-53},
      doi = {10.11648/j.ijhpebs.20210701.15},
      url = {https://doi.org/10.11648/j.ijhpebs.20210701.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20210701.15},
      abstract = {Nigeria bears 10% of global HIV burden and contributes 32% to global unmet-need for Prevention of Mother to Child transmission of HIV (PMTCT), which together with heterosexual transmission are the epidemic’s key drivers as PMTCT clinics show approximately 45% serodiscordance rates among couples. WHO recommends accelerated Anti-retroviral Therapy initiation for all persons living with HIV (PLHIV) for improved quality-of-life and preventing new vertical and horizontal infections, using same drug – Emtricitabine, Tenofovir and Efaverenz (once daily Atripla). The policy paper seeks to make a case that the National PMTCT task team and the Federal Ministry of health of Nigeria, should make a policy change, and shift from the current Option B PMTCT option. The option provides Antiretroviral drugs (ARVs) to pregnant HIV positive women who do for PMTCT, but discontinue them after cessation of breast-feeding, when the viral load is above 500cells/mm3. It proposes that the country should rather adopt the test and treat all policy for all HIV infected persons. The methodology entails the search and use of literature to demonstrate the multiple advantages of early commencement of treatment for all new of HIV infections, considering this has been shown to reduce morbidity and mortality. The results indicate that test and treat all for life, is now less complex as same drug regimen are used in PMTCT and other non PMTCT adult infections. Studies also show that virologic suppression (undetectable) leads to prevention of new HIV transmission (untransmitable), and this applies to different modes of HIV transmission. The brief concludes by proposing that the Federal Ministry of Health, the National AIDS Control agency, and all actors in Nigeria’s HIV terrains should adopt the WHO test and treat guidelines. This remains a critical step for the elimination of Paediatric HIV infections.},
     year = {2021}
    }
    

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Author Information
  • Faculty of Medical Sciences, University of Jos, Jos, Nigeria

  • Department of Paediatrics, Benue State University Teaching Hospital, Makurdi, Nigeria

  • Faculty of Medical Sciences, University of Jos, Jos, Nigeria

  • Faculty of Medical Sciences, University of Jos, Jos, Nigeria

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