Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study

Robert Mahamudi Mussa; Aliocha Natuhoyila Nkodila; Naomi Asani Kiala; Justin Mpila Muilu; Gilbert Lelo Mananga

doi:doi:10.11648/j.ijhpebs.20210702.12

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Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study

Robert Mahamudi Mussa, Aliocha Natuhoyila Nkodila, Naomi Asani Kiala, Justin Mpila Muilu, Gilbert Lelo Mananga

Published in International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 7, Issue 2)

Received: 6 July 2021 Accepted: 21 July 2021 Published: 6 August 2021

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Abstract

Background and aim: Neurocognitive disorders are described in people living with HIV (PLWH) on therapeutic anti-retroviral (TARVs), but their determinants are not known. The aim of this study is to determine the determinants of neurocognitive disorders in PLHIV on TARVs. Methods: 45 PLWH on ARVs were analyzed in a cross-sectional study conducted in 2 ARV distribution centers in Kinshasa from August to October 2020. Sociodemographic variables, perceived stress score and neurocognitive disorders were the parameters of interest. A logistic regression made it possible to identify the determinants. The threshold of statistical significance was p <0.05. Results: We recorded 45 patients who met our inclusion criteria. The female sex was the majority (71.1%), the mean age was (50.6 plus or minus 9.1 years) with a sex ratio 3F: 1H, asymptomatic neurocognitive disorders (AND) was more noted in our patients and they was more in the attention and calculation component (60%). All of our patients were under stress, 58% of whom were under high stress; there has been a clear correlation between stress and AND, age> 60 years [aOR: 4.09, 95% CI: 1.63), p = 0.022), unmarried status [aOR: 4.40, 95% CI: 1.79-6.63), p = 0.017) and high perceived stress [aOR: 4.97, 95% CI: 2.72-9.85, p = 0.008) were independent risk factors associated with cognitive impairment in the population of study. Conclusion: The prevalence of neurocognitive disorders was high in PLWH on TARVs and these disorders concerned adults, educated, living alone with a predominance of women. Their determinants were age> 60, loneliness and high stress level.

Published in	International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 7, Issue 2)
DOI	10.11648/j.ijhpebs.20210702.12
Page(s)	61-65
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Asymptomatic Neurocognitive Disorders, Age> 60 Years, Female Sex, High Stress, PLWH on TARVs

References

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[21]	Jean-Michel Thuren; Nicole Baumann. Stress, Pathologies et Immunités. Médecine-Sciences, Flammarion, 2003: 126-132.

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Robert Mahamudi Mussa, Aliocha Natuhoyila Nkodila, Naomi Asani Kiala, Justin Mpila Muilu, Gilbert Lelo Mananga. (2021). Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 7(2), 61-65. https://doi.org/10.11648/j.ijhpebs.20210702.12

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ACS Style

Robert Mahamudi Mussa; Aliocha Natuhoyila Nkodila; Naomi Asani Kiala; Justin Mpila Muilu; Gilbert Lelo Mananga. Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2021, 7(2), 61-65. doi: 10.11648/j.ijhpebs.20210702.12

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AMA Style

Robert Mahamudi Mussa, Aliocha Natuhoyila Nkodila, Naomi Asani Kiala, Justin Mpila Muilu, Gilbert Lelo Mananga. Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study. Int J HIV/AIDS Prev Educ Behav Sci. 2021;7(2):61-65. doi: 10.11648/j.ijhpebs.20210702.12

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@article{10.11648/j.ijhpebs.20210702.12,
  author = {Robert Mahamudi Mussa and Aliocha Natuhoyila Nkodila and Naomi Asani Kiala and Justin Mpila Muilu and Gilbert Lelo Mananga},
  title = {Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {7},
  number = {2},
  pages = {61-65},
  doi = {10.11648/j.ijhpebs.20210702.12},
  url = {https://doi.org/10.11648/j.ijhpebs.20210702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20210702.12},
  abstract = {Background and aim: Neurocognitive disorders are described in people living with HIV (PLWH) on therapeutic anti-retroviral (TARVs), but their determinants are not known. The aim of this study is to determine the determinants of neurocognitive disorders in PLHIV on TARVs. Methods: 45 PLWH on ARVs were analyzed in a cross-sectional study conducted in 2 ARV distribution centers in Kinshasa from August to October 2020. Sociodemographic variables, perceived stress score and neurocognitive disorders were the parameters of interest. A logistic regression made it possible to identify the determinants. The threshold of statistical significance was p Results: We recorded 45 patients who met our inclusion criteria. The female sex was the majority (71.1%), the mean age was (50.6 plus or minus 9.1 years) with a sex ratio 3F: 1H, asymptomatic neurocognitive disorders (AND) was more noted in our patients and they was more in the attention and calculation component (60%). All of our patients were under stress, 58% of whom were under high stress; there has been a clear correlation between stress and AND, age> 60 years [aOR: 4.09, 95% CI: 1.63), p = 0.022), unmarried status [aOR: 4.40, 95% CI: 1.79-6.63), p = 0.017) and high perceived stress [aOR: 4.97, 95% CI: 2.72-9.85, p = 0.008) were independent risk factors associated with cognitive impairment in the population of study. Conclusion: The prevalence of neurocognitive disorders was high in PLWH on TARVs and these disorders concerned adults, educated, living alone with a predominance of women. Their determinants were age> 60, loneliness and high stress level.},
 year = {2021}
}

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TY  - JOUR
T1  - Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study
AU  - Robert Mahamudi Mussa
AU  - Aliocha Natuhoyila Nkodila
AU  - Naomi Asani Kiala
AU  - Justin Mpila Muilu
AU  - Gilbert Lelo Mananga
Y1  - 2021/08/06
PY  - 2021
N1  - https://doi.org/10.11648/j.ijhpebs.20210702.12
DO  - 10.11648/j.ijhpebs.20210702.12
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 61
EP  - 65
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20210702.12
AB  - Background and aim: Neurocognitive disorders are described in people living with HIV (PLWH) on therapeutic anti-retroviral (TARVs), but their determinants are not known. The aim of this study is to determine the determinants of neurocognitive disorders in PLHIV on TARVs. Methods: 45 PLWH on ARVs were analyzed in a cross-sectional study conducted in 2 ARV distribution centers in Kinshasa from August to October 2020. Sociodemographic variables, perceived stress score and neurocognitive disorders were the parameters of interest. A logistic regression made it possible to identify the determinants. The threshold of statistical significance was p Results: We recorded 45 patients who met our inclusion criteria. The female sex was the majority (71.1%), the mean age was (50.6 plus or minus 9.1 years) with a sex ratio 3F: 1H, asymptomatic neurocognitive disorders (AND) was more noted in our patients and they was more in the attention and calculation component (60%). All of our patients were under stress, 58% of whom were under high stress; there has been a clear correlation between stress and AND, age> 60 years [aOR: 4.09, 95% CI: 1.63), p = 0.022), unmarried status [aOR: 4.40, 95% CI: 1.79-6.63), p = 0.017) and high perceived stress [aOR: 4.97, 95% CI: 2.72-9.85, p = 0.008) were independent risk factors associated with cognitive impairment in the population of study. Conclusion: The prevalence of neurocognitive disorders was high in PLWH on TARVs and these disorders concerned adults, educated, living alone with a predominance of women. Their determinants were age> 60, loneliness and high stress level.
VL  - 7
IS  - 2
ER  -

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Author Information

Robert Mahamudi Mussa

Neuropsychopathological Center, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Aliocha Natuhoyila Nkodila

Faculty of Family Medicine, Protestant University in Congo, Kinshasa, Democratic Republic of the Congo
Naomi Asani Kiala

Neuropsychopathological Center, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Justin Mpila Muilu

Neuropsychopathological Center, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Gilbert Lelo Mananga

Neuropsychopathological Center, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

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Plain Text BibTeX RIS

APA Style

Robert Mahamudi Mussa, Aliocha Natuhoyila Nkodila, Naomi Asani Kiala, Justin Mpila Muilu, Gilbert Lelo Mananga. (2021). Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 7(2), 61-65. https://doi.org/10.11648/j.ijhpebs.20210702.12

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ACS Style

Robert Mahamudi Mussa; Aliocha Natuhoyila Nkodila; Naomi Asani Kiala; Justin Mpila Muilu; Gilbert Lelo Mananga. Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2021, 7(2), 61-65. doi: 10.11648/j.ijhpebs.20210702.12

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AMA Style

Robert Mahamudi Mussa, Aliocha Natuhoyila Nkodila, Naomi Asani Kiala, Justin Mpila Muilu, Gilbert Lelo Mananga. Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study. Int J HIV/AIDS Prev Educ Behav Sci. 2021;7(2):61-65. doi: 10.11648/j.ijhpebs.20210702.12

Copy | Download

@article{10.11648/j.ijhpebs.20210702.12,
  author = {Robert Mahamudi Mussa and Aliocha Natuhoyila Nkodila and Naomi Asani Kiala and Justin Mpila Muilu and Gilbert Lelo Mananga},
  title = {Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {7},
  number = {2},
  pages = {61-65},
  doi = {10.11648/j.ijhpebs.20210702.12},
  url = {https://doi.org/10.11648/j.ijhpebs.20210702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20210702.12},
  abstract = {Background and aim: Neurocognitive disorders are described in people living with HIV (PLWH) on therapeutic anti-retroviral (TARVs), but their determinants are not known. The aim of this study is to determine the determinants of neurocognitive disorders in PLHIV on TARVs. Methods: 45 PLWH on ARVs were analyzed in a cross-sectional study conducted in 2 ARV distribution centers in Kinshasa from August to October 2020. Sociodemographic variables, perceived stress score and neurocognitive disorders were the parameters of interest. A logistic regression made it possible to identify the determinants. The threshold of statistical significance was p Results: We recorded 45 patients who met our inclusion criteria. The female sex was the majority (71.1%), the mean age was (50.6 plus or minus 9.1 years) with a sex ratio 3F: 1H, asymptomatic neurocognitive disorders (AND) was more noted in our patients and they was more in the attention and calculation component (60%). All of our patients were under stress, 58% of whom were under high stress; there has been a clear correlation between stress and AND, age> 60 years [aOR: 4.09, 95% CI: 1.63), p = 0.022), unmarried status [aOR: 4.40, 95% CI: 1.79-6.63), p = 0.017) and high perceived stress [aOR: 4.97, 95% CI: 2.72-9.85, p = 0.008) were independent risk factors associated with cognitive impairment in the population of study. Conclusion: The prevalence of neurocognitive disorders was high in PLWH on TARVs and these disorders concerned adults, educated, living alone with a predominance of women. Their determinants were age> 60, loneliness and high stress level.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Sociodemographic and Psychological Determinants of Neurocognitive Disorders in People Living with HIV on TARVs in Kinshasa: Cross-sectional Study
AU  - Robert Mahamudi Mussa
AU  - Aliocha Natuhoyila Nkodila
AU  - Naomi Asani Kiala
AU  - Justin Mpila Muilu
AU  - Gilbert Lelo Mananga
Y1  - 2021/08/06
PY  - 2021
N1  - https://doi.org/10.11648/j.ijhpebs.20210702.12
DO  - 10.11648/j.ijhpebs.20210702.12
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 61
EP  - 65
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20210702.12
AB  - Background and aim: Neurocognitive disorders are described in people living with HIV (PLWH) on therapeutic anti-retroviral (TARVs), but their determinants are not known. The aim of this study is to determine the determinants of neurocognitive disorders in PLHIV on TARVs. Methods: 45 PLWH on ARVs were analyzed in a cross-sectional study conducted in 2 ARV distribution centers in Kinshasa from August to October 2020. Sociodemographic variables, perceived stress score and neurocognitive disorders were the parameters of interest. A logistic regression made it possible to identify the determinants. The threshold of statistical significance was p Results: We recorded 45 patients who met our inclusion criteria. The female sex was the majority (71.1%), the mean age was (50.6 plus or minus 9.1 years) with a sex ratio 3F: 1H, asymptomatic neurocognitive disorders (AND) was more noted in our patients and they was more in the attention and calculation component (60%). All of our patients were under stress, 58% of whom were under high stress; there has been a clear correlation between stress and AND, age> 60 years [aOR: 4.09, 95% CI: 1.63), p = 0.022), unmarried status [aOR: 4.40, 95% CI: 1.79-6.63), p = 0.017) and high perceived stress [aOR: 4.97, 95% CI: 2.72-9.85, p = 0.008) were independent risk factors associated with cognitive impairment in the population of study. Conclusion: The prevalence of neurocognitive disorders was high in PLWH on TARVs and these disorders concerned adults, educated, living alone with a predominance of women. Their determinants were age> 60, loneliness and high stress level.
VL  - 7
IS  - 2
ER  -

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