Human Brucellosis - New Public Health Problem in Bulgaria

Milena Dimitrova Karcheva; Vanya Atanasova Birdanova; Margarita Lubomirova Alexandrova

doi:doi:10.11648/j.ijidt.20170204.11

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Human Brucellosis - New Public Health Problem in Bulgaria

Milena Dimitrova Karcheva, Vanya Atanasova Birdanova, Margarita Lubomirova Alexandrova

Published in International Journal of Infectious Diseases and Therapy (Volume 2, Issue 4)

Received: 3 April 2017 Accepted: 20 May 2017 Published: 14 July 2017

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Abstract

The aim of this study was to describe trends over time of human brucellosis (HB) based on national surveillance data from 1992 to 2016 in Bulgaria and to assess the factors of its re-emergence after 50 years elimination. Retrospective analytical study was applied and performed descriptive, spatial and time series analyses using national aggregated data for HB incidence from National Center of Infectious and Parasitic Diseases (NCIPD)-Sofia. During the 25-year period, 190 confirmed cases were reported, resulting in annual incidence of 0.10 cases per 100,000 populations. Dynamic model of the epidemic process and risk factor were analyzed. The fitted Autoregressive integrated moving average (ARIMA) model of HB incidence also was selected. There were differentiated two cycles of infection spreading out lasting 12-13 years with two epidemic waves (1996 and 2002). Greater incidence of HB was recorded during the peaks of epidemic waves in the second epidemic cycle – 0.52-0.76/100,000 population. Re-emergence of brucellosis in Bulgaria started from areas bordering endemic countries and gradually extended inland. The geographic location of Bulgaria as external border of European Union (EU) and transit crossroad among Asia, Africa and Europe increases the risk of HB re-emergence to the country. Involvement of all responsible institutions for public healthcare is required.

Published in	International Journal of Infectious Diseases and Therapy (Volume 2, Issue 4)
DOI	10.11648/j.ijidt.20170204.11
Page(s)	66-71
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Human Brucellosis, Epidemiology, Public Health, Risk Factors, Bulgaria

References

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Milena Dimitrova Karcheva, Vanya Atanasova Birdanova, Margarita Lubomirova Alexandrova. (2017). Human Brucellosis - New Public Health Problem in Bulgaria. International Journal of Infectious Diseases and Therapy, 2(4), 66-71. https://doi.org/10.11648/j.ijidt.20170204.11

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ACS Style

Milena Dimitrova Karcheva; Vanya Atanasova Birdanova; Margarita Lubomirova Alexandrova. Human Brucellosis - New Public Health Problem in Bulgaria. Int. J. Infect. Dis. Ther. 2017, 2(4), 66-71. doi: 10.11648/j.ijidt.20170204.11

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AMA Style

Milena Dimitrova Karcheva, Vanya Atanasova Birdanova, Margarita Lubomirova Alexandrova. Human Brucellosis - New Public Health Problem in Bulgaria. Int J Infect Dis Ther. 2017;2(4):66-71. doi: 10.11648/j.ijidt.20170204.11

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@article{10.11648/j.ijidt.20170204.11,
  author = {Milena Dimitrova Karcheva and Vanya Atanasova Birdanova and Margarita Lubomirova Alexandrova},
  title = {Human Brucellosis - New Public Health Problem in Bulgaria},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {2},
  number = {4},
  pages = {66-71},
  doi = {10.11648/j.ijidt.20170204.11},
  url = {https://doi.org/10.11648/j.ijidt.20170204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20170204.11},
  abstract = {The aim of this study was to describe trends over time of human brucellosis (HB) based on national surveillance data from 1992 to 2016 in Bulgaria and to assess the factors of its re-emergence after 50 years elimination. Retrospective analytical study was applied and performed descriptive, spatial and time series analyses using national aggregated data for HB incidence from National Center of Infectious and Parasitic Diseases (NCIPD)-Sofia. During the 25-year period, 190 confirmed cases were reported, resulting in annual incidence of 0.10 cases per 100,000 populations. Dynamic model of the epidemic process and risk factor were analyzed. The fitted Autoregressive integrated moving average (ARIMA) model of HB incidence also was selected. There were differentiated two cycles of infection spreading out lasting 12-13 years with two epidemic waves (1996 and 2002). Greater incidence of HB was recorded during the peaks of epidemic waves in the second epidemic cycle – 0.52-0.76/100,000 population. Re-emergence of brucellosis in Bulgaria started from areas bordering endemic countries and gradually extended inland. The geographic location of Bulgaria as external border of European Union (EU) and transit crossroad among Asia, Africa and Europe increases the risk of HB re-emergence to the country. Involvement of all responsible institutions for public healthcare is required.},
 year = {2017}
}

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TY  - JOUR
T1  - Human Brucellosis - New Public Health Problem in Bulgaria
AU  - Milena Dimitrova Karcheva
AU  - Vanya Atanasova Birdanova
AU  - Margarita Lubomirova Alexandrova
Y1  - 2017/07/14
PY  - 2017
N1  - https://doi.org/10.11648/j.ijidt.20170204.11
DO  - 10.11648/j.ijidt.20170204.11
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 66
EP  - 71
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20170204.11
AB  - The aim of this study was to describe trends over time of human brucellosis (HB) based on national surveillance data from 1992 to 2016 in Bulgaria and to assess the factors of its re-emergence after 50 years elimination. Retrospective analytical study was applied and performed descriptive, spatial and time series analyses using national aggregated data for HB incidence from National Center of Infectious and Parasitic Diseases (NCIPD)-Sofia. During the 25-year period, 190 confirmed cases were reported, resulting in annual incidence of 0.10 cases per 100,000 populations. Dynamic model of the epidemic process and risk factor were analyzed. The fitted Autoregressive integrated moving average (ARIMA) model of HB incidence also was selected. There were differentiated two cycles of infection spreading out lasting 12-13 years with two epidemic waves (1996 and 2002). Greater incidence of HB was recorded during the peaks of epidemic waves in the second epidemic cycle – 0.52-0.76/100,000 population. Re-emergence of brucellosis in Bulgaria started from areas bordering endemic countries and gradually extended inland. The geographic location of Bulgaria as external border of European Union (EU) and transit crossroad among Asia, Africa and Europe increases the risk of HB re-emergence to the country. Involvement of all responsible institutions for public healthcare is required.
VL  - 2
IS  - 4
ER  -

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Author Information

Milena Dimitrova Karcheva

Department of Epidemiology, Parasitology and Tropical Medicine, Medical University, Pleven, Bulgaria
Vanya Atanasova Birdanova

Department of Hygiene, Medical Ecology, Occupational Disease and Disaster Medicine, Medical University, Pleven, Bulgaria
Margarita Lubomirova Alexandrova

Department of Biophysics, Medical University, Pleven, Bulgaria

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APA Style

Milena Dimitrova Karcheva, Vanya Atanasova Birdanova, Margarita Lubomirova Alexandrova. (2017). Human Brucellosis - New Public Health Problem in Bulgaria. International Journal of Infectious Diseases and Therapy, 2(4), 66-71. https://doi.org/10.11648/j.ijidt.20170204.11

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ACS Style

Milena Dimitrova Karcheva; Vanya Atanasova Birdanova; Margarita Lubomirova Alexandrova. Human Brucellosis - New Public Health Problem in Bulgaria. Int. J. Infect. Dis. Ther. 2017, 2(4), 66-71. doi: 10.11648/j.ijidt.20170204.11

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AMA Style

Milena Dimitrova Karcheva, Vanya Atanasova Birdanova, Margarita Lubomirova Alexandrova. Human Brucellosis - New Public Health Problem in Bulgaria. Int J Infect Dis Ther. 2017;2(4):66-71. doi: 10.11648/j.ijidt.20170204.11

Copy | Download

@article{10.11648/j.ijidt.20170204.11,
  author = {Milena Dimitrova Karcheva and Vanya Atanasova Birdanova and Margarita Lubomirova Alexandrova},
  title = {Human Brucellosis - New Public Health Problem in Bulgaria},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {2},
  number = {4},
  pages = {66-71},
  doi = {10.11648/j.ijidt.20170204.11},
  url = {https://doi.org/10.11648/j.ijidt.20170204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20170204.11},
  abstract = {The aim of this study was to describe trends over time of human brucellosis (HB) based on national surveillance data from 1992 to 2016 in Bulgaria and to assess the factors of its re-emergence after 50 years elimination. Retrospective analytical study was applied and performed descriptive, spatial and time series analyses using national aggregated data for HB incidence from National Center of Infectious and Parasitic Diseases (NCIPD)-Sofia. During the 25-year period, 190 confirmed cases were reported, resulting in annual incidence of 0.10 cases per 100,000 populations. Dynamic model of the epidemic process and risk factor were analyzed. The fitted Autoregressive integrated moving average (ARIMA) model of HB incidence also was selected. There were differentiated two cycles of infection spreading out lasting 12-13 years with two epidemic waves (1996 and 2002). Greater incidence of HB was recorded during the peaks of epidemic waves in the second epidemic cycle – 0.52-0.76/100,000 population. Re-emergence of brucellosis in Bulgaria started from areas bordering endemic countries and gradually extended inland. The geographic location of Bulgaria as external border of European Union (EU) and transit crossroad among Asia, Africa and Europe increases the risk of HB re-emergence to the country. Involvement of all responsible institutions for public healthcare is required.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Human Brucellosis - New Public Health Problem in Bulgaria
AU  - Milena Dimitrova Karcheva
AU  - Vanya Atanasova Birdanova
AU  - Margarita Lubomirova Alexandrova
Y1  - 2017/07/14
PY  - 2017
N1  - https://doi.org/10.11648/j.ijidt.20170204.11
DO  - 10.11648/j.ijidt.20170204.11
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 66
EP  - 71
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20170204.11
AB  - The aim of this study was to describe trends over time of human brucellosis (HB) based on national surveillance data from 1992 to 2016 in Bulgaria and to assess the factors of its re-emergence after 50 years elimination. Retrospective analytical study was applied and performed descriptive, spatial and time series analyses using national aggregated data for HB incidence from National Center of Infectious and Parasitic Diseases (NCIPD)-Sofia. During the 25-year period, 190 confirmed cases were reported, resulting in annual incidence of 0.10 cases per 100,000 populations. Dynamic model of the epidemic process and risk factor were analyzed. The fitted Autoregressive integrated moving average (ARIMA) model of HB incidence also was selected. There were differentiated two cycles of infection spreading out lasting 12-13 years with two epidemic waves (1996 and 2002). Greater incidence of HB was recorded during the peaks of epidemic waves in the second epidemic cycle – 0.52-0.76/100,000 population. Re-emergence of brucellosis in Bulgaria started from areas bordering endemic countries and gradually extended inland. The geographic location of Bulgaria as external border of European Union (EU) and transit crossroad among Asia, Africa and Europe increases the risk of HB re-emergence to the country. Involvement of all responsible institutions for public healthcare is required.
VL  - 2
IS  - 4
ER  -

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