Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou

Attinsounon Cossi Angelo; Wanvoegbe Armand; Agbodandé Anthelme; Alassani Adebayo; Fandohan Wilfried; Tognon Francis

doi:doi:10.11648/j.ijidt.20220702.12

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Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou

Attinsounon Cossi Angelo, Wanvoegbe Armand, Agbodandé Anthelme, Alassani Adebayo, Fandohan Wilfried, Tognon Francis

Published in International Journal of Infectious Diseases and Therapy (Volume 7, Issue 2)

Received: 3 March 2022 Accepted: 12 April 2022 Published: 20 April 2022

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Abstract

Introduction: Antiretrovirals have improved the life expectancy of people living with HIV (PLHIV). The evaluation of quality of life and its improvement is now an important element of care. The current study assessed the quality of life and identified associated factors with adults living with HIV who were followed at the CHUD Borgou. Methods: A case-control study was conducted from August to October 2018. Cases of PLHIV aged 15 years and older, were recruited through systematic sampling with steps equal to 2 based on the order of arrival of patients at the site. The controls were composed of apparently healthy, HIV-negative individuals recruited in the community in 10 neighborhoods selected at random out of 58 in the city of Parakou. A pen rotation was used to choose the direction to follow and households were selected with a step size of 4. Each PLHIV is associated with two HIV-negative respondents matched on age, sex, and average monthly income. The generic score composed of 36 questions "SF-36" was used to assess the quality of life of the participants. These questions are grouped into three categories exploring physical, mental, and self-perceived health changes, respectively. Respondents gave oral consent. The favorable opinion of the ethics committee for Biomedical research of the University of Parakou was obtained. Data were entered and analyzed using Epi-Info 7.2.2 software. The general linear regression model was used to identify independent factors associated with quality of life. Results: There were 222 PLHIV and 444 HIV-negative subjects. The mean quality of life score of PLHIV was higher than that of HIV-negative subjects in all dimensions: physical health (56.04 vs. 50.52; p ˂ 0.000), mental health (40.15 vs. 35.16; p ˂ 0.000), and perceived health (67.00 vs. 59.40; p < 0.000). PLHIV had a low vitality score compared with controls (53.67 vs 54.85; p = 0.215). Independent factors associated with quality of life were: age < 40 years (p=0.001), male gender (p=0.046), shared HIV status with spouse (p=0.045), existence of psychological support (p=0.026), length of time since testing (p=0.041), last CD4 ≥ 500 (p=0.025). Conclusion: Several factors contribute to a better quality of life for PLHIV compared to the community. The impact of free care in Benin on the quality of life of PLHIV deserves to be evaluated in the long term.

Published in	International Journal of Infectious Diseases and Therapy (Volume 7, Issue 2)
DOI	10.11648/j.ijidt.20220702.12
Page(s)	29-34
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antiretrovirals, Associated Factors, Benin, PLHIV, Quality of Life

References

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Attinsounon Cossi Angelo, Wanvoegbe Armand, Agbodandé Anthelme, Alassani Adebayo, Fandohan Wilfried, et al. (2022). Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou. International Journal of Infectious Diseases and Therapy, 7(2), 29-34. https://doi.org/10.11648/j.ijidt.20220702.12

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Attinsounon Cossi Angelo; Wanvoegbe Armand; Agbodandé Anthelme; Alassani Adebayo; Fandohan Wilfried, et al. Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou. Int. J. Infect. Dis. Ther. 2022, 7(2), 29-34. doi: 10.11648/j.ijidt.20220702.12

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Attinsounon Cossi Angelo, Wanvoegbe Armand, Agbodandé Anthelme, Alassani Adebayo, Fandohan Wilfried, et al. Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou. Int J Infect Dis Ther. 2022;7(2):29-34. doi: 10.11648/j.ijidt.20220702.12

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@article{10.11648/j.ijidt.20220702.12,
  author = {Attinsounon Cossi Angelo and Wanvoegbe Armand and Agbodandé Anthelme and Alassani Adebayo and Fandohan Wilfried and Tognon Francis},
  title = {Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {7},
  number = {2},
  pages = {29-34},
  doi = {10.11648/j.ijidt.20220702.12},
  url = {https://doi.org/10.11648/j.ijidt.20220702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20220702.12},
  abstract = {Introduction: Antiretrovirals have improved the life expectancy of people living with HIV (PLHIV). The evaluation of quality of life and its improvement is now an important element of care. The current study assessed the quality of life and identified associated factors with adults living with HIV who were followed at the CHUD Borgou. Methods: A case-control study was conducted from August to October 2018. Cases of PLHIV aged 15 years and older, were recruited through systematic sampling with steps equal to 2 based on the order of arrival of patients at the site. The controls were composed of apparently healthy, HIV-negative individuals recruited in the community in 10 neighborhoods selected at random out of 58 in the city of Parakou. A pen rotation was used to choose the direction to follow and households were selected with a step size of 4. Each PLHIV is associated with two HIV-negative respondents matched on age, sex, and average monthly income. The generic score composed of 36 questions "SF-36" was used to assess the quality of life of the participants. These questions are grouped into three categories exploring physical, mental, and self-perceived health changes, respectively. Respondents gave oral consent. The favorable opinion of the ethics committee for Biomedical research of the University of Parakou was obtained. Data were entered and analyzed using Epi-Info 7.2.2 software. The general linear regression model was used to identify independent factors associated with quality of life. Results: There were 222 PLHIV and 444 HIV-negative subjects. The mean quality of life score of PLHIV was higher than that of HIV-negative subjects in all dimensions: physical health (56.04 vs. 50.52; p ˂ 0.000), mental health (40.15 vs. 35.16; p ˂ 0.000), and perceived health (67.00 vs. 59.40; p Conclusion: Several factors contribute to a better quality of life for PLHIV compared to the community. The impact of free care in Benin on the quality of life of PLHIV deserves to be evaluated in the long term.},
 year = {2022}
}

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TY - JOUR
T1 - Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou
AU - Attinsounon Cossi Angelo
AU - Wanvoegbe Armand
AU - Agbodandé Anthelme
AU - Alassani Adebayo
AU - Fandohan Wilfried
AU - Tognon Francis
Y1 - 2022/04/20
PY - 2022
N1 - https://doi.org/10.11648/j.ijidt.20220702.12
DO - 10.11648/j.ijidt.20220702.12
T2 - International Journal of Infectious Diseases and Therapy
JF - International Journal of Infectious Diseases and Therapy
JO - International Journal of Infectious Diseases and Therapy
SP - 29
EP - 34
PB - Science Publishing Group
SN - 2578-966X
UR - https://doi.org/10.11648/j.ijidt.20220702.12
AB - Introduction: Antiretrovirals have improved the life expectancy of people living with HIV (PLHIV). The evaluation of quality of life and its improvement is now an important element of care. The current study assessed the quality of life and identified associated factors with adults living with HIV who were followed at the CHUD Borgou. Methods: A case-control study was conducted from August to October 2018. Cases of PLHIV aged 15 years and older, were recruited through systematic sampling with steps equal to 2 based on the order of arrival of patients at the site. The controls were composed of apparently healthy, HIV-negative individuals recruited in the community in 10 neighborhoods selected at random out of 58 in the city of Parakou. A pen rotation was used to choose the direction to follow and households were selected with a step size of 4. Each PLHIV is associated with two HIV-negative respondents matched on age, sex, and average monthly income. The generic score composed of 36 questions "SF-36" was used to assess the quality of life of the participants. These questions are grouped into three categories exploring physical, mental, and self-perceived health changes, respectively. Respondents gave oral consent. The favorable opinion of the ethics committee for Biomedical research of the University of Parakou was obtained. Data were entered and analyzed using Epi-Info 7.2.2 software. The general linear regression model was used to identify independent factors associated with quality of life. Results: There were 222 PLHIV and 444 HIV-negative subjects. The mean quality of life score of PLHIV was higher than that of HIV-negative subjects in all dimensions: physical health (56.04 vs. 50.52; p ˂ 0.000), mental health (40.15 vs. 35.16; p ˂ 0.000), and perceived health (67.00 vs. 59.40; p Conclusion: Several factors contribute to a better quality of life for PLHIV compared to the community. The impact of free care in Benin on the quality of life of PLHIV deserves to be evaluated in the long term.
VL - 7
IS - 2
ER -

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Author Information

Attinsounon Cossi Angelo

Department of Medicine and Medical Specialties, Regional and Teaching Hospital of Borgou, Faculty of Medicine, University of Parakou, Parakou, Republic of Benin
Wanvoegbe Armand

Department of Medicine and Medical Specialties, National and Teaching Hospital of Cotonou, Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Republic of Benin
Agbodandé Anthelme

Department of Medicine and Medical Specialties, National and Teaching Hospital of Cotonou, Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Republic of Benin
Alassani Adebayo

Department of Medicine and Medical Specialties, Regional and Teaching Hospital of Borgou, Faculty of Medicine, University of Parakou, Parakou, Republic of Benin
Fandohan Wilfried

Department of Medicine and Medical Specialties, Regional and Teaching Hospital of Borgou, Faculty of Medicine, University of Parakou, Parakou, Republic of Benin
Tognon Francis

Department of Medicine and Medical Specialties, Regional and Teaching Hospital of Borgou, Faculty of Medicine, University of Parakou, Parakou, Republic of Benin

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Attinsounon Cossi Angelo, Wanvoegbe Armand, Agbodandé Anthelme, Alassani Adebayo, Fandohan Wilfried, et al. (2022). Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou. International Journal of Infectious Diseases and Therapy, 7(2), 29-34. https://doi.org/10.11648/j.ijidt.20220702.12

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Attinsounon Cossi Angelo; Wanvoegbe Armand; Agbodandé Anthelme; Alassani Adebayo; Fandohan Wilfried, et al. Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou. Int. J. Infect. Dis. Ther. 2022, 7(2), 29-34. doi: 10.11648/j.ijidt.20220702.12

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Attinsounon Cossi Angelo, Wanvoegbe Armand, Agbodandé Anthelme, Alassani Adebayo, Fandohan Wilfried, et al. Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou. Int J Infect Dis Ther. 2022;7(2):29-34. doi: 10.11648/j.ijidt.20220702.12

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@article{10.11648/j.ijidt.20220702.12,
  author = {Attinsounon Cossi Angelo and Wanvoegbe Armand and Agbodandé Anthelme and Alassani Adebayo and Fandohan Wilfried and Tognon Francis},
  title = {Quality of Life and Associated Factors in HIV-infected Adults Undergoing Antiretroviral Treatment at CHUD-Borgou},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {7},
  number = {2},
  pages = {29-34},
  doi = {10.11648/j.ijidt.20220702.12},
  url = {https://doi.org/10.11648/j.ijidt.20220702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20220702.12},
  abstract = {Introduction: Antiretrovirals have improved the life expectancy of people living with HIV (PLHIV). The evaluation of quality of life and its improvement is now an important element of care. The current study assessed the quality of life and identified associated factors with adults living with HIV who were followed at the CHUD Borgou. Methods: A case-control study was conducted from August to October 2018. Cases of PLHIV aged 15 years and older, were recruited through systematic sampling with steps equal to 2 based on the order of arrival of patients at the site. The controls were composed of apparently healthy, HIV-negative individuals recruited in the community in 10 neighborhoods selected at random out of 58 in the city of Parakou. A pen rotation was used to choose the direction to follow and households were selected with a step size of 4. Each PLHIV is associated with two HIV-negative respondents matched on age, sex, and average monthly income. The generic score composed of 36 questions "SF-36" was used to assess the quality of life of the participants. These questions are grouped into three categories exploring physical, mental, and self-perceived health changes, respectively. Respondents gave oral consent. The favorable opinion of the ethics committee for Biomedical research of the University of Parakou was obtained. Data were entered and analyzed using Epi-Info 7.2.2 software. The general linear regression model was used to identify independent factors associated with quality of life. Results: There were 222 PLHIV and 444 HIV-negative subjects. The mean quality of life score of PLHIV was higher than that of HIV-negative subjects in all dimensions: physical health (56.04 vs. 50.52; p ˂ 0.000), mental health (40.15 vs. 35.16; p ˂ 0.000), and perceived health (67.00 vs. 59.40; p Conclusion: Several factors contribute to a better quality of life for PLHIV compared to the community. The impact of free care in Benin on the quality of life of PLHIV deserves to be evaluated in the long term.},
 year = {2022}
}

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