@article{10.11648/j.ijidt.20230803.12,
  author = {Daouda Thioub and Viviane Marie Pierre Cisse-Diallo and Massamba Ba and Moustapha Diop and Louise Fortes and Ndeye Aissatou Lakhe and Daye Ka and Khardiata Diallo Mbaye and Aboubakar Sidikh Badiane and Ndeye Maguette Fall and Ndeye Fatou Ngom-Gueye and Moussa Seydi},
  title = {Tetanus in the Elderly in Dakar: Epidemiological, Clinical, Evolutionary Aspects and Associated Factors of Death},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {8},
  number = {3},
  pages = {87-90},
  doi = {10.11648/j.ijidt.20230803.12},
  url = {https://doi.org/10.11648/j.ijidt.20230803.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20230803.12},
  abstract = {Senegal is one of the African countries where tetanus in children and adults remains a concern. Until now, there have been few studies on tetanus in elderly people. The objective of this study was to describe the epidemiological, clinical and evolutionary aspects of tetanus in elderly people. This was a descriptive and analytical retrospective study of the records of patients hospitalized at the Infectious Diseases Department of Fann National University Hospital in Dakar for tetanus in person aged 60 years and older, from January 1, 2009, to December 31, 2019. Data were collected from medical records. Multivariable logistic regression was used to evaluate potential risk factors of death. We included 962 cases of tetanus of all ages. Among the cases, 98 were elderly persons, representing a proportional morbidity of 10.10%. A male predominance was noted with a sex ratio (M/F) of 1.45. Fifty-seven patients (58.17%) had at least one comorbidity and they were dominated by hypertension (32 cases) and diabetes (13 cases). More than half of the patients (63.3%) were unaware of their vaccination status and only 03 patients were up to date. The portal of entry was mainly integumentary (72.45%). The incubation period was ≥ 7 Days in 88.78% of cases, and the invasion period ≥ 48 hours in 60.20% of patients. The generalized clinical form represented 95% of cases. The evolution was marked by complications in 78.60% of cases. Complications were dominated by bacterial infections (45.90%). The average length of hospitalization was 13.5 ± 2.9 days [1 - 49 days]. Forty-eight (48) patients died during hospitalization, representing a hospital case fatality of 48.97%. In multivariate analysis, only a duration of invasion < 48 hours (p=0.032) and the occurrence of complications were significantly associated with death (p=0.004). Our study reveals once again the seriousness of tetanus in elderly. Moreover, our data confirms the need to update prognostic classifications by introducing certain factors that have been identified in numerous studies as being associated with patient death, such as advanced age, presence of comorbidities and occurrence of a complication.},
 year = {2023}
}

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TY  - JOUR
T1  - Tetanus in the Elderly in Dakar: Epidemiological, Clinical, Evolutionary Aspects and Associated Factors of Death
AU  - Daouda Thioub
AU  - Viviane Marie Pierre Cisse-Diallo
AU  - Massamba Ba
AU  - Moustapha Diop
AU  - Louise Fortes
AU  - Ndeye Aissatou Lakhe
AU  - Daye Ka
AU  - Khardiata Diallo Mbaye
AU  - Aboubakar Sidikh Badiane
AU  - Ndeye Maguette Fall
AU  - Ndeye Fatou Ngom-Gueye
AU  - Moussa Seydi
Y1  - 2023/07/20
PY  - 2023
N1  - https://doi.org/10.11648/j.ijidt.20230803.12
DO  - 10.11648/j.ijidt.20230803.12
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 87
EP  - 90
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20230803.12
AB  - Senegal is one of the African countries where tetanus in children and adults remains a concern. Until now, there have been few studies on tetanus in elderly people. The objective of this study was to describe the epidemiological, clinical and evolutionary aspects of tetanus in elderly people. This was a descriptive and analytical retrospective study of the records of patients hospitalized at the Infectious Diseases Department of Fann National University Hospital in Dakar for tetanus in person aged 60 years and older, from January 1, 2009, to December 31, 2019. Data were collected from medical records. Multivariable logistic regression was used to evaluate potential risk factors of death. We included 962 cases of tetanus of all ages. Among the cases, 98 were elderly persons, representing a proportional morbidity of 10.10%. A male predominance was noted with a sex ratio (M/F) of 1.45. Fifty-seven patients (58.17%) had at least one comorbidity and they were dominated by hypertension (32 cases) and diabetes (13 cases). More than half of the patients (63.3%) were unaware of their vaccination status and only 03 patients were up to date. The portal of entry was mainly integumentary (72.45%). The incubation period was ≥ 7 Days in 88.78% of cases, and the invasion period ≥ 48 hours in 60.20% of patients. The generalized clinical form represented 95% of cases. The evolution was marked by complications in 78.60% of cases. Complications were dominated by bacterial infections (45.90%). The average length of hospitalization was 13.5 ± 2.9 days [1 - 49 days]. Forty-eight (48) patients died during hospitalization, representing a hospital case fatality of 48.97%. In multivariate analysis, only a duration of invasion < 48 hours (p=0.032) and the occurrence of complications were significantly associated with death (p=0.004). Our study reveals once again the seriousness of tetanus in elderly. Moreover, our data confirms the need to update prognostic classifications by introducing certain factors that have been identified in numerous studies as being associated with patient death, such as advanced age, presence of comorbidities and occurrence of a complication.
VL  - 8
IS  - 3
ER  - 

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