Malnutrition in children is associated with signs of liver dysfunction such as hepatic steatosis, which increases morbidity and mortality. This research aims to study the epidemiological, clinical and paraclinical aspects of hepatic steatosis in malnourished children at the CNHU-HKM and CHU-MEL of Cotonou. This was a descriptive and analytical cross-sectional study that took place from May 1 to July 31, 2017. Malnourished children aged 06 months to 05 years old who were hospitalized or received outpatient care during the study period were included. An exhaustive sampling of all children meeting the eligibility criteria during the study period was conducted. Ninety-four malnourished children were included in the study. Their mean age was 18.47 months. The hospital prevalence of hepatic steatosis was 60.6%. Hepatic steatosis was diffuse and homogeneous without focal lesions. Clinically, it was significantly associated with hepatomegaly, underweight and severe chronic malnutrition. A statistically significant association was also observed between, respectively, non-supplementation with iron/folic acid, recent non-adherence to EPI vaccines and hepatic steatosis. Biologically, there was a statistically significant association between hepatic steatosis and transaminases, gamma GT, triglycerides, albuminemia. Hepatic steatosis is common in malnourished children. There is a clinico-biological correlation. Liver ultrasound should be systematic in cases of malnutrition.
| Published in | International Journal of Nutrition and Food Sciences (Volume 10, Issue 6) |
| DOI | 10.11648/j.ijnfs.20211006.12 |
| Page(s) | 126-133 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Hepatic Steatosis, Malnutrition, Associated Factors, Benin
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APA Style
Florence Alihonou, Patricia Yekpe, Francis Honnorat Lalya, Mohammed Dakin, Marcelline D’Almeida Hounnou, et al. (2021). Hepatic Steatosis and Radiological, Clinical and Biological Correlation in Malnourished Children in Two Referral Hospitals in Cotonou. International Journal of Nutrition and Food Sciences, 10(6), 126-133. https://doi.org/10.11648/j.ijnfs.20211006.12
ACS Style
Florence Alihonou; Patricia Yekpe; Francis Honnorat Lalya; Mohammed Dakin; Marcelline D’Almeida Hounnou, et al. Hepatic Steatosis and Radiological, Clinical and Biological Correlation in Malnourished Children in Two Referral Hospitals in Cotonou. Int. J. Nutr. Food Sci. 2021, 10(6), 126-133. doi: 10.11648/j.ijnfs.20211006.12
AMA Style
Florence Alihonou, Patricia Yekpe, Francis Honnorat Lalya, Mohammed Dakin, Marcelline D’Almeida Hounnou, et al. Hepatic Steatosis and Radiological, Clinical and Biological Correlation in Malnourished Children in Two Referral Hospitals in Cotonou. Int J Nutr Food Sci. 2021;10(6):126-133. doi: 10.11648/j.ijnfs.20211006.12
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author = {Florence Alihonou and Patricia Yekpe and Francis Honnorat Lalya and Mohammed Dakin and Marcelline D’Almeida Hounnou and Olivier Biaou},
title = {Hepatic Steatosis and Radiological, Clinical and Biological Correlation in Malnourished Children in Two Referral Hospitals in Cotonou},
journal = {International Journal of Nutrition and Food Sciences},
volume = {10},
number = {6},
pages = {126-133},
doi = {10.11648/j.ijnfs.20211006.12},
url = {https://doi.org/10.11648/j.ijnfs.20211006.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20211006.12},
abstract = {Malnutrition in children is associated with signs of liver dysfunction such as hepatic steatosis, which increases morbidity and mortality. This research aims to study the epidemiological, clinical and paraclinical aspects of hepatic steatosis in malnourished children at the CNHU-HKM and CHU-MEL of Cotonou. This was a descriptive and analytical cross-sectional study that took place from May 1 to July 31, 2017. Malnourished children aged 06 months to 05 years old who were hospitalized or received outpatient care during the study period were included. An exhaustive sampling of all children meeting the eligibility criteria during the study period was conducted. Ninety-four malnourished children were included in the study. Their mean age was 18.47 months. The hospital prevalence of hepatic steatosis was 60.6%. Hepatic steatosis was diffuse and homogeneous without focal lesions. Clinically, it was significantly associated with hepatomegaly, underweight and severe chronic malnutrition. A statistically significant association was also observed between, respectively, non-supplementation with iron/folic acid, recent non-adherence to EPI vaccines and hepatic steatosis. Biologically, there was a statistically significant association between hepatic steatosis and transaminases, gamma GT, triglycerides, albuminemia. Hepatic steatosis is common in malnourished children. There is a clinico-biological correlation. Liver ultrasound should be systematic in cases of malnutrition.},
year = {2021}
}
TY - JOUR T1 - Hepatic Steatosis and Radiological, Clinical and Biological Correlation in Malnourished Children in Two Referral Hospitals in Cotonou AU - Florence Alihonou AU - Patricia Yekpe AU - Francis Honnorat Lalya AU - Mohammed Dakin AU - Marcelline D’Almeida Hounnou AU - Olivier Biaou Y1 - 2021/11/23 PY - 2021 N1 - https://doi.org/10.11648/j.ijnfs.20211006.12 DO - 10.11648/j.ijnfs.20211006.12 T2 - International Journal of Nutrition and Food Sciences JF - International Journal of Nutrition and Food Sciences JO - International Journal of Nutrition and Food Sciences SP - 126 EP - 133 PB - Science Publishing Group SN - 2327-2716 UR - https://doi.org/10.11648/j.ijnfs.20211006.12 AB - Malnutrition in children is associated with signs of liver dysfunction such as hepatic steatosis, which increases morbidity and mortality. This research aims to study the epidemiological, clinical and paraclinical aspects of hepatic steatosis in malnourished children at the CNHU-HKM and CHU-MEL of Cotonou. This was a descriptive and analytical cross-sectional study that took place from May 1 to July 31, 2017. Malnourished children aged 06 months to 05 years old who were hospitalized or received outpatient care during the study period were included. An exhaustive sampling of all children meeting the eligibility criteria during the study period was conducted. Ninety-four malnourished children were included in the study. Their mean age was 18.47 months. The hospital prevalence of hepatic steatosis was 60.6%. Hepatic steatosis was diffuse and homogeneous without focal lesions. Clinically, it was significantly associated with hepatomegaly, underweight and severe chronic malnutrition. A statistically significant association was also observed between, respectively, non-supplementation with iron/folic acid, recent non-adherence to EPI vaccines and hepatic steatosis. Biologically, there was a statistically significant association between hepatic steatosis and transaminases, gamma GT, triglycerides, albuminemia. Hepatic steatosis is common in malnourished children. There is a clinico-biological correlation. Liver ultrasound should be systematic in cases of malnutrition. VL - 10 IS - 6 ER -
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