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A Case of Multiple Myeloma Revealed by a Acute Otitis Media in Adults

Received: 28 March 2020     Accepted: 10 June 2020     Published: 20 June 2020
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Abstract

Multiple myeloma or Kahler's disease is a malignant hemopathy characterized by a clonal proliferation of tumor plasma cells that invade the hematopoietic bone marrow. It is often discovered preferentially during spine, pelvis and ribs pain. Kahler's disease are rarely discovered during ENT infections. We report a case of a 58-year-old female patient that we exanimated in our ENT service for acute suppurative otitis media. The remainder of the examination revealed a swelling in the breast and functional impairment of the right upper limb. The maxillofacial CT- scan revealed lytic lacunar images of maxilla and cranial vault. Conventional X-ray displayed a fracture of the right humeral shaft. The positive diagnosis of multiple myeloma was made using bone marrow biopsy that has shown the presence of pathological plasmatic cells proliferation. Furthermore examination such as the plasma protein electrophoresis found hypo-gamma-globulinemia. Analysis of urinary sediment found κ -like Bence-Jones proteinuria. We provided Biphosphonates and analgesics treatment in addition to that of acute otitis media. Unfortunately, the death occurred six months later before he was able to benefit from a more invasive treatment protocol. This observation shows us that acute otitis media should not be trivialized, as it required a rigorous clinical examination and may surprise us.

Published in International Journal of Otorhinolaryngology (Volume 6, Issue 1)
DOI 10.11648/j.ijo.20200601.15
Page(s) 19-22
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Multiple Myeloma, Acute Otitis Media, Gap in Images

References
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[2] Pittet-Barbier L., Coulomb M. Atteintes osseuses dans le myélome. Encycl Méd Chir (Editions Scientifiques et Médicales Elsevier SAS, Paris, tous droits réservés), Radiodiagnostic – Neuroradiologie-Appareil locomoteur, 31-192-D-10, 2003, 14 p.
[3] Fouquet G., Guidez S., Herbaux C., Demarquette H., Leleu X. Myélome multiple indolent. La Revue de médecine interne 35 (2014) 243–249.
[4] Manier S., Leleu X. Myélome multiple : diagnostic clinique et perspective de traitement. Recommandations de l’International Myeloma Working Group (IMWG). Immuno-analyse et biologie spécialisée 2011; 26: 125–136.
[5] Ouédraogo P V., Boudzoumou B. D. E., Nahantchi A., Ndiaye M. Un infarctus cérébral révélant un myélome multiple. NPG Neurologie - Psychiatrie - Gériatrie 2018; 18: 170–173.
[6] Renou F., Gerber A., Moiton M P., Ferrandiz D., Yvin J L. Arthrite à pneumocoque révélant un myélome. La Revue de médecine interne 2007; 28: 186–187.
[7] Dougé A., Lemal R, Chaleteix C. Pomalidomide dans les myélomes multiples. Bull Cancer 2017; 104: 707–713.
[8] Lescanne E., Lanotte P., Pondaven S., Autret-Leca E. Otites moyennes aiguës. EMC (Elsevier Masson SAS, Paris), Oto-rhino-laryngologie, 20-085-A-10, 2006.
[9] Sarkis G., El Hachem N. L'otite moyenne aiguë, séreuse ou récidivante : l'avis du pédiatre. Kinesither Rev 2012; 12 (132): 12–7.
[10] Jahidi A., Zalagh M., Errami N., Akhiri M, Benariba F. Conduite à tenir devant une otite moyenne aigue. Espérance Médicale 2010; 17 (174): 667-72.
[11] Manier S., de la Contrie M C, Hieulle J., Daniel A., Facon T. Myélome multiple : des critères diagnostiques et pronostiques renouvelés et de forts espoirs thérapeutiques. Presse Med. 2019; 48: 825–831.
[12] Bouvarda B., Royer M., Chappard D., Audran M., Hoppé E., Legrand E. Gammapathie monoclonale de signification indéterminée, myélome multiple et ostéoporose. Revue du rhumatisme 2010; 77: 144–148.
[13] Debiais F., Vix J., Durand G., Azaïs I. Prise en charge des lésions osseuses du myélome multiple : quelles particularités ? Revue du rhumatisme monographies 2017; 84: 197–204.
[14] Touzeau C., Moreau P. Multiple myeloma imaging. Diagnostic and Interventional Imaging 2013 ; 94 (2): 190–92.
[15] Bouatay A., Hizem S., Ben Youssef Y., Sayari F., Braham N., Khélif A., Kortas M. Myélome multiple : aspect clinique, diagnostic biologique et pronostic. Immuno-analyse et biologie spécialisée 2013; 28: 30–35.
[16] Vincent H., Chaïbi P. Traitement du myélome du sujet âgé : intérêt des nouvelles molécules. NPG Neurologie - Psychiatrie - Gériatrie 2008; 8: 10–18.
Cite This Article
  • APA Style

    Samaké Djibril, Sidibé Youssouf, Samaké Magara, Cissé Bana, Bathily Moussa, et al. (2020). A Case of Multiple Myeloma Revealed by a Acute Otitis Media in Adults. International Journal of Otorhinolaryngology, 6(1), 19-22. https://doi.org/10.11648/j.ijo.20200601.15

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    ACS Style

    Samaké Djibril; Sidibé Youssouf; Samaké Magara; Cissé Bana; Bathily Moussa, et al. A Case of Multiple Myeloma Revealed by a Acute Otitis Media in Adults. Int. J. Otorhinolaryngol. 2020, 6(1), 19-22. doi: 10.11648/j.ijo.20200601.15

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    AMA Style

    Samaké Djibril, Sidibé Youssouf, Samaké Magara, Cissé Bana, Bathily Moussa, et al. A Case of Multiple Myeloma Revealed by a Acute Otitis Media in Adults. Int J Otorhinolaryngol. 2020;6(1):19-22. doi: 10.11648/j.ijo.20200601.15

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  • @article{10.11648/j.ijo.20200601.15,
      author = {Samaké Djibril and Sidibé Youssouf and Samaké Magara and Cissé Bana and Bathily Moussa and Haidara Abdoul Wahab and Koné Fatogoma Issa and Maïga Youma Mamadou and Konaté Fatoumata and Dara Yatemelou and Traoré Sounkalo and Doumbia-Singaré Kadidiatou and Timbo Samba Karim and Kéïta Mohamed Amadou},
      title = {A Case of Multiple Myeloma Revealed by a Acute Otitis Media in Adults},
      journal = {International Journal of Otorhinolaryngology},
      volume = {6},
      number = {1},
      pages = {19-22},
      doi = {10.11648/j.ijo.20200601.15},
      url = {https://doi.org/10.11648/j.ijo.20200601.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijo.20200601.15},
      abstract = {Multiple myeloma or Kahler's disease is a malignant hemopathy characterized by a clonal proliferation of tumor plasma cells that invade the hematopoietic bone marrow. It is often discovered preferentially during spine, pelvis and ribs pain. Kahler's disease are rarely discovered during ENT infections. We report a case of a 58-year-old female patient that we exanimated in our ENT service for acute suppurative otitis media. The remainder of the examination revealed a swelling in the breast and functional impairment of the right upper limb. The maxillofacial CT- scan revealed lytic lacunar images of maxilla and cranial vault. Conventional X-ray displayed a fracture of the right humeral shaft. The positive diagnosis of multiple myeloma was made using bone marrow biopsy that has shown the presence of pathological plasmatic cells proliferation. Furthermore examination such as the plasma protein electrophoresis found hypo-gamma-globulinemia. Analysis of urinary sediment found κ -like Bence-Jones proteinuria. We provided Biphosphonates and analgesics treatment in addition to that of acute otitis media. Unfortunately, the death occurred six months later before he was able to benefit from a more invasive treatment protocol. This observation shows us that acute otitis media should not be trivialized, as it required a rigorous clinical examination and may surprise us.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - A Case of Multiple Myeloma Revealed by a Acute Otitis Media in Adults
    AU  - Samaké Djibril
    AU  - Sidibé Youssouf
    AU  - Samaké Magara
    AU  - Cissé Bana
    AU  - Bathily Moussa
    AU  - Haidara Abdoul Wahab
    AU  - Koné Fatogoma Issa
    AU  - Maïga Youma Mamadou
    AU  - Konaté Fatoumata
    AU  - Dara Yatemelou
    AU  - Traoré Sounkalo
    AU  - Doumbia-Singaré Kadidiatou
    AU  - Timbo Samba Karim
    AU  - Kéïta Mohamed Amadou
    Y1  - 2020/06/20
    PY  - 2020
    N1  - https://doi.org/10.11648/j.ijo.20200601.15
    DO  - 10.11648/j.ijo.20200601.15
    T2  - International Journal of Otorhinolaryngology
    JF  - International Journal of Otorhinolaryngology
    JO  - International Journal of Otorhinolaryngology
    SP  - 19
    EP  - 22
    PB  - Science Publishing Group
    SN  - 2472-2413
    UR  - https://doi.org/10.11648/j.ijo.20200601.15
    AB  - Multiple myeloma or Kahler's disease is a malignant hemopathy characterized by a clonal proliferation of tumor plasma cells that invade the hematopoietic bone marrow. It is often discovered preferentially during spine, pelvis and ribs pain. Kahler's disease are rarely discovered during ENT infections. We report a case of a 58-year-old female patient that we exanimated in our ENT service for acute suppurative otitis media. The remainder of the examination revealed a swelling in the breast and functional impairment of the right upper limb. The maxillofacial CT- scan revealed lytic lacunar images of maxilla and cranial vault. Conventional X-ray displayed a fracture of the right humeral shaft. The positive diagnosis of multiple myeloma was made using bone marrow biopsy that has shown the presence of pathological plasmatic cells proliferation. Furthermore examination such as the plasma protein electrophoresis found hypo-gamma-globulinemia. Analysis of urinary sediment found κ -like Bence-Jones proteinuria. We provided Biphosphonates and analgesics treatment in addition to that of acute otitis media. Unfortunately, the death occurred six months later before he was able to benefit from a more invasive treatment protocol. This observation shows us that acute otitis media should not be trivialized, as it required a rigorous clinical examination and may surprise us.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • ENT and Head and Neck Surgery Department, Commune V Reference Health Center, Bamako, Mali

  • ENT and Head and Neck Surgery Department, CHU Mère-Enfant "Le Luxembourg", Bamako, Mali

  • Nephrology-Hemodialysis Unit, Kayes Regional Hospital, Kayes, Mali

  • Rheumatology Unit, Commune V Reference Health Center, Bamako, Mali

  • Haemato-Oncology Department, CHU Point-G, Bamako, Mali

  • ENT and Head and Neck Surgery Department, Ségou Regional Hospital, Segou, Mali

  • ENT and Head and Neck Surgery Department, CHU-Gabriel Touré, Bamako, Mali

  • ENT and Head and Neck Surgery Department, Commune V Reference Health Center, Bamako, Mali

  • ENT and Head and Neck Surgery Department, Commune V Reference Health Center, Bamako, Mali

  • Medical Imaging Department, Commune V Reference Health Center, Bamako, Mali

  • ENT and Head and Neck Surgery Department, CHU-Gabriel Touré, Bamako, Mali

  • ENT and Head and Neck Surgery Department, CHU-Gabriel Touré, Bamako, Mali

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