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Primitive Cavum Tuberculosis: An Unusual Location of Mycobacteria

Received: 12 May 2022     Accepted: 26 May 2022     Published: 31 May 2022
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Abstract

Objective: This is a 17-year-old patient with no known history who had consulted the ENT department of the CHU-Gabriel Touré for persistent obstruction of the right nose. Its clinical history dates back to approximately 03 years, marked by a unilateral right nasal obstruction of progressive installation and permanent evolution associated with purulent posterior rhinorrhea, anosmia, right hypoacusis, headaches in helmet and an alteration of the state. general. There was no notion of cough, evening fever or epistaxis. These symptoms motivated several unspecified treatments without improvement. Before the onset of ptosis and ipsilateral blindness, he consulted us for support. We noted on otoscopy a dull right eardrum with a hearing loss of 25 decibels (db). Ophthalmological examination showed ptosis, ophthalmoplegia and blindness on the right side. Nasofibroscopy revealed a budding lesion taking up the entire right half of the roof of the nasopharynx filling the Rosenmüller fossa. There was no palpable cervical adenopathy. HIV serology was negative. Maxillofacial computed tomography revealed a rectilinear nasal sinus osteolytic expansive tumoral process extending to the optic nerve as well as to the oculomotor muscles with grade II proptosis (figure 1). Two repeated biopsies of the lesion found tuberculosis in front of a gigantocellular epithelioid granuloma with caseous necrosis. Intradermal tuberculin reaction and AFB sputum became negative. The chest X-ray was normal. We carried out the surgical excision of the lesion and the diagnosis of tuberculosis was confirmed by the anatomopathological examination. The patient was placed under anti-tuberculosis verification according to the 2RHZE / 4RH Protocol. The evolution was favorable after two months with normalization of the signs on nasofibroscopy.

Published in International Journal of Otorhinolaryngology (Volume 8, Issue 1)
DOI 10.11648/j.ijo.20220801.12
Page(s) 14-16
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Primary Tuberculosis, Cavum, Carcinoma

References
[1] H shelter, et al. Diagnostic means of tuberculosis. Rev Pneumol Clin (2016), http://dx.doi.org/10.1016/j.pneumo.2016.06.003
[2] A. El Ayoubi, Benhammou A., F. El Ayoubi. Extranodal ORL primitive tuberculosis.
[3] Morvan JB, Poisel E, Vatin L, Rivière D, Cathelinaud O, Bousquet F, et al. ENT manifestations of tuberculosis. EMC - Otorhinolaryngology 2015; 10 (2): 1-11 [Article 20-925-B-10].
[4] H. Snene et al. Pseudotumoral tuberculosis, a difficult diagnosis Journal of Respiratory Diseases EMC 2018 35, 295-304.
[5] Touati M et al. The pseudo-tumoral form of primary nasopharyngeal tuberculosis: two new observations and review of the literature. Pan African Medical Journal. 2013; 14: 63. http://www.panafrican-med-journal.com/content/article/14/63/full/
[6] Epidemiology and Research on Tuberculosis in Mali: Current Status. Malian Review of Infectious Diseases and Microbiology 2015, Volume 6.
[7] Lecointre F, Marandas P, Micheau C, Lacombe H, Schwaab G, Cachin Y. Tuberculosis of the mucous membranes of the VADS: clinical study on 37 cases followed at IIGR. Ann Otolaryngol Chir Cervicofac 1980; 97 (6): 423-33.
[8] S. A. Ebongue. Tuberculosis of the cavum: about 11 cases. rev. respiratory diseases 2012; 29 (1): 117, doi: 10.1016/j.rmr.2011.10.386.
[9] Naoki Sawada et al. Nasopharyngeal tuberculosis. J Infect Chemother Japan 2013 J Infect. DOI 10.1007/s10156-013-0574-0.
[10] S. Kharoubi. Miliary tuberculosis of the pharynx or Isambert Pharyngeal tuberculosis disease. Ann of Otolaryngology and Head and Neck Surgery 125 (2008) 218-223.
Cite This Article
  • APA Style

    N’faly Konaté, Kassim Diarra, Drissa Kaloga Bagayoko, Sidibé Youssouf, Keïta Mohamed. (2022). Primitive Cavum Tuberculosis: An Unusual Location of Mycobacteria. International Journal of Otorhinolaryngology, 8(1), 14-16. https://doi.org/10.11648/j.ijo.20220801.12

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    ACS Style

    N’faly Konaté; Kassim Diarra; Drissa Kaloga Bagayoko; Sidibé Youssouf; Keïta Mohamed. Primitive Cavum Tuberculosis: An Unusual Location of Mycobacteria. Int. J. Otorhinolaryngol. 2022, 8(1), 14-16. doi: 10.11648/j.ijo.20220801.12

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    AMA Style

    N’faly Konaté, Kassim Diarra, Drissa Kaloga Bagayoko, Sidibé Youssouf, Keïta Mohamed. Primitive Cavum Tuberculosis: An Unusual Location of Mycobacteria. Int J Otorhinolaryngol. 2022;8(1):14-16. doi: 10.11648/j.ijo.20220801.12

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  • @article{10.11648/j.ijo.20220801.12,
      author = {N’faly Konaté and Kassim Diarra and Drissa Kaloga Bagayoko and Sidibé Youssouf and Keïta Mohamed},
      title = {Primitive Cavum Tuberculosis: An Unusual Location of Mycobacteria},
      journal = {International Journal of Otorhinolaryngology},
      volume = {8},
      number = {1},
      pages = {14-16},
      doi = {10.11648/j.ijo.20220801.12},
      url = {https://doi.org/10.11648/j.ijo.20220801.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijo.20220801.12},
      abstract = {Objective: This is a 17-year-old patient with no known history who had consulted the ENT department of the CHU-Gabriel Touré for persistent obstruction of the right nose. Its clinical history dates back to approximately 03 years, marked by a unilateral right nasal obstruction of progressive installation and permanent evolution associated with purulent posterior rhinorrhea, anosmia, right hypoacusis, headaches in helmet and an alteration of the state. general. There was no notion of cough, evening fever or epistaxis. These symptoms motivated several unspecified treatments without improvement. Before the onset of ptosis and ipsilateral blindness, he consulted us for support. We noted on otoscopy a dull right eardrum with a hearing loss of 25 decibels (db). Ophthalmological examination showed ptosis, ophthalmoplegia and blindness on the right side. Nasofibroscopy revealed a budding lesion taking up the entire right half of the roof of the nasopharynx filling the Rosenmüller fossa. There was no palpable cervical adenopathy. HIV serology was negative. Maxillofacial computed tomography revealed a rectilinear nasal sinus osteolytic expansive tumoral process extending to the optic nerve as well as to the oculomotor muscles with grade II proptosis (figure 1). Two repeated biopsies of the lesion found tuberculosis in front of a gigantocellular epithelioid granuloma with caseous necrosis. Intradermal tuberculin reaction and AFB sputum became negative. The chest X-ray was normal. We carried out the surgical excision of the lesion and the diagnosis of tuberculosis was confirmed by the anatomopathological examination. The patient was placed under anti-tuberculosis verification according to the 2RHZE / 4RH Protocol. The evolution was favorable after two months with normalization of the signs on nasofibroscopy.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Primitive Cavum Tuberculosis: An Unusual Location of Mycobacteria
    AU  - N’faly Konaté
    AU  - Kassim Diarra
    AU  - Drissa Kaloga Bagayoko
    AU  - Sidibé Youssouf
    AU  - Keïta Mohamed
    Y1  - 2022/05/31
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ijo.20220801.12
    DO  - 10.11648/j.ijo.20220801.12
    T2  - International Journal of Otorhinolaryngology
    JF  - International Journal of Otorhinolaryngology
    JO  - International Journal of Otorhinolaryngology
    SP  - 14
    EP  - 16
    PB  - Science Publishing Group
    SN  - 2472-2413
    UR  - https://doi.org/10.11648/j.ijo.20220801.12
    AB  - Objective: This is a 17-year-old patient with no known history who had consulted the ENT department of the CHU-Gabriel Touré for persistent obstruction of the right nose. Its clinical history dates back to approximately 03 years, marked by a unilateral right nasal obstruction of progressive installation and permanent evolution associated with purulent posterior rhinorrhea, anosmia, right hypoacusis, headaches in helmet and an alteration of the state. general. There was no notion of cough, evening fever or epistaxis. These symptoms motivated several unspecified treatments without improvement. Before the onset of ptosis and ipsilateral blindness, he consulted us for support. We noted on otoscopy a dull right eardrum with a hearing loss of 25 decibels (db). Ophthalmological examination showed ptosis, ophthalmoplegia and blindness on the right side. Nasofibroscopy revealed a budding lesion taking up the entire right half of the roof of the nasopharynx filling the Rosenmüller fossa. There was no palpable cervical adenopathy. HIV serology was negative. Maxillofacial computed tomography revealed a rectilinear nasal sinus osteolytic expansive tumoral process extending to the optic nerve as well as to the oculomotor muscles with grade II proptosis (figure 1). Two repeated biopsies of the lesion found tuberculosis in front of a gigantocellular epithelioid granuloma with caseous necrosis. Intradermal tuberculin reaction and AFB sputum became negative. The chest X-ray was normal. We carried out the surgical excision of the lesion and the diagnosis of tuberculosis was confirmed by the anatomopathological examination. The patient was placed under anti-tuberculosis verification according to the 2RHZE / 4RH Protocol. The evolution was favorable after two months with normalization of the signs on nasofibroscopy.
    VL  - 8
    IS  - 1
    ER  - 

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Author Information
  • ENT and Head and Neck Surgery Department, University Hospital Center “Gabriel Touré”, Bamako, Mali

  • ENT and Head and Neck Surgery Department, University Hospital Center “Gabriel Touré”, Bamako, Mali

  • ENT and Head and Neck Surgery Department, University Hospital Center Mother-Child “Le Luxembourg”, Bamako, Mali

  • ENT and Head and Neck Surgery Department, University Hospital Center Mother-Child “Le Luxembourg”, Bamako, Mali

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