@article{10.11648/j.ijo.20220802.15,
  author = {Tallat Najeeb and Nisa Siddiqui and Abdul Hameed Bhatti},
  title = {Comparison of Early Symptoms of COVID-19 Patients with Different Variants Before and After Vaccination},
  journal = {International Journal of Otorhinolaryngology},
  volume = {8},
  number = {2},
  pages = {52-56},
  doi = {10.11648/j.ijo.20220802.15},
  url = {https://doi.org/10.11648/j.ijo.20220802.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijo.20220802.15},
  abstract = {Corona virus disease (COVID-19) first detected in Wuhan, China in December 2019, spread rapidly to many geographical areas within a few months. As a result, on March 11, 2020 the World Health Organization (WHO) declared COVID-19 as a global pandemic. This disease mainly affected the respiratory system. The review of literature showed a diverse array of clinical features within 2-14 days, that range from asymptomatic and mildly symptomatic to severe illness. However, there is a need to recognize the diversity of clinical features produced by COVID-19 and its variants in Pakistan. The objective of this study is to determine the frequency of various clinical features during the initial stages of COVID-19 infection. This descriptive cross-sectional study was conducted at Fazaia Medical College and PAF hospital Islamabad from April 2020 to March 2022 after approval from the institutional ethical committee. By using WHO sample size calculator, the calculated sample size was 385. The data was collected by using a self-administered questionnaire. Only those patients were included in the study who had a positive RT-PCR for SARS-COVID-19. Data was entered and analyzed by using SPSS version 22.0. Chi.square test was applied. We divided our study into two phases. Out of 385 patients, 218 were included in phase-1 while 167 were included in phase-2. Dominant symptoms of phase 1 were fever (92.7%), anosmia / parosmia (82.1%), taste disturbance (81.2%), sore throat (74.3%) and lethargy (74.3%) but the dominant symptoms of phase 2 were fever (91.6%), sore throat (80.8%), lethargy (78.4%), odynophagia (73.7%) and cough (70.7%). P-value was < 0.001 and was extremely significant for dyspnea, loss of taste and anosmia. This study concludes that the most reliable symptoms for clinical diagnosis and referral for PCR are Fever, Sore throat and Lethargy.},
 year = {2022}
}

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TY  - JOUR
T1  - Comparison of Early Symptoms of COVID-19 Patients with Different Variants Before and After Vaccination
AU  - Tallat Najeeb
AU  - Nisa Siddiqui
AU  - Abdul Hameed Bhatti
Y1  - 2022/08/15
PY  - 2022
N1  - https://doi.org/10.11648/j.ijo.20220802.15
DO  - 10.11648/j.ijo.20220802.15
T2  - International Journal of Otorhinolaryngology
JF  - International Journal of Otorhinolaryngology
JO  - International Journal of Otorhinolaryngology
SP  - 52
EP  - 56
PB  - Science Publishing Group
SN  - 2472-2413
UR  - https://doi.org/10.11648/j.ijo.20220802.15
AB  - Corona virus disease (COVID-19) first detected in Wuhan, China in December 2019, spread rapidly to many geographical areas within a few months. As a result, on March 11, 2020 the World Health Organization (WHO) declared COVID-19 as a global pandemic. This disease mainly affected the respiratory system. The review of literature showed a diverse array of clinical features within 2-14 days, that range from asymptomatic and mildly symptomatic to severe illness. However, there is a need to recognize the diversity of clinical features produced by COVID-19 and its variants in Pakistan. The objective of this study is to determine the frequency of various clinical features during the initial stages of COVID-19 infection. This descriptive cross-sectional study was conducted at Fazaia Medical College and PAF hospital Islamabad from April 2020 to March 2022 after approval from the institutional ethical committee. By using WHO sample size calculator, the calculated sample size was 385. The data was collected by using a self-administered questionnaire. Only those patients were included in the study who had a positive RT-PCR for SARS-COVID-19. Data was entered and analyzed by using SPSS version 22.0. Chi.square test was applied. We divided our study into two phases. Out of 385 patients, 218 were included in phase-1 while 167 were included in phase-2. Dominant symptoms of phase 1 were fever (92.7%), anosmia / parosmia (82.1%), taste disturbance (81.2%), sore throat (74.3%) and lethargy (74.3%) but the dominant symptoms of phase 2 were fever (91.6%), sore throat (80.8%), lethargy (78.4%), odynophagia (73.7%) and cough (70.7%). P-value was < 0.001 and was extremely significant for dyspnea, loss of taste and anosmia. This study concludes that the most reliable symptoms for clinical diagnosis and referral for PCR are Fever, Sore throat and Lethargy.
VL  - 8
IS  - 2
ER  - 

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