The effect of licorice extract on non-specific immune function of giant salamanders was studied by intraperitoneal injection. The results showed that the lysozyme activity in the drug group increased, and the lysozyme activity increased with the increase of dose. From the 7th day onwards, each sampling of the drug group showed significant differences compared to the control group (P<0.05). The phagocytic activity of macrophages in the drug group showed some fluctuations, but there was no significant difference compared to the control group. The white blood cell volume value of the high-dose group gradually increased in the first three samplings, and showed a significant difference compared to the control group at 14 days (P<0.05). It decreased slightly in the last two samplings, but was still higher than the control group at the same time. The spleen organ coefficient of the low-dose group was (0.7 ± 0.01) % at 28 days, higher than that of the control group (0.4 ± 0.05) %, and the high-dose group was (0.7 ± 0.07) % at 14 days, higher than that of the control group (0.4 ± 0.02) %. Both differences were significant (P<0.05). After the last sampling (28 days), artificial infection with Aeromonas hydrophila bacteria resulted in a mortality rate of 80% in the control group, 50% in the low-dose group, and 30% in the high-dose group, all lower than the control group. The drug group also had higher immune protection rates than the control group. The results indicate that intraperitoneal injection of licorice extract can improve the immune function and disease resistance of giant salamanders to a certain extent.
| Published in | Science Frontiers (Volume 5, Issue 4) |
| DOI | 10.11648/j.sf.20240504.11 |
| Page(s) | 130-135 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Intraperitoneal Injection, Licorice, Giant Salamander, Immune
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APA Style
Wang, W., Liu, P., Ning, Y., Feng, Y., Dou, L., et al. (2024). The Immunomodulatory Effect of Intraperitoneal Injection of Licorice Extract on Giant Salamander. Science Frontiers, 5(4), 130-135. https://doi.org/10.11648/j.sf.20240504.11
ACS Style
Wang, W.; Liu, P.; Ning, Y.; Feng, Y.; Dou, L., et al. The Immunomodulatory Effect of Intraperitoneal Injection of Licorice Extract on Giant Salamander. Sci. Front. 2024, 5(4), 130-135. doi: 10.11648/j.sf.20240504.11
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Download@article{10.11648/j.sf.20240504.11,
author = {Wenbo Wang and Pin Liu and Yue Ning and Yalong Feng and Lingling Dou and Ping Wang and Ruimin Xi and Minfei Yan},
title = {The Immunomodulatory Effect of Intraperitoneal Injection of Licorice Extract on Giant Salamander
},
journal = {Science Frontiers},
volume = {5},
number = {4},
pages = {130-135},
doi = {10.11648/j.sf.20240504.11},
url = {https://doi.org/10.11648/j.sf.20240504.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sf.20240504.11},
abstract = {The effect of licorice extract on non-specific immune function of giant salamanders was studied by intraperitoneal injection. The results showed that the lysozyme activity in the drug group increased, and the lysozyme activity increased with the increase of dose. From the 7th day onwards, each sampling of the drug group showed significant differences compared to the control group (PAeromonas hydrophila bacteria resulted in a mortality rate of 80% in the control group, 50% in the low-dose group, and 30% in the high-dose group, all lower than the control group. The drug group also had higher immune protection rates than the control group. The results indicate that intraperitoneal injection of licorice extract can improve the immune function and disease resistance of giant salamanders to a certain extent.
},
year = {2024}
}
TY - JOUR T1 - The Immunomodulatory Effect of Intraperitoneal Injection of Licorice Extract on Giant Salamander AU - Wenbo Wang AU - Pin Liu AU - Yue Ning AU - Yalong Feng AU - Lingling Dou AU - Ping Wang AU - Ruimin Xi AU - Minfei Yan Y1 - 2024/11/12 PY - 2024 N1 - https://doi.org/10.11648/j.sf.20240504.11 DO - 10.11648/j.sf.20240504.11 T2 - Science Frontiers JF - Science Frontiers JO - Science Frontiers SP - 130 EP - 135 PB - Science Publishing Group SN - 2994-7030 UR - https://doi.org/10.11648/j.sf.20240504.11 AB - The effect of licorice extract on non-specific immune function of giant salamanders was studied by intraperitoneal injection. The results showed that the lysozyme activity in the drug group increased, and the lysozyme activity increased with the increase of dose. From the 7th day onwards, each sampling of the drug group showed significant differences compared to the control group (PAeromonas hydrophila bacteria resulted in a mortality rate of 80% in the control group, 50% in the low-dose group, and 30% in the high-dose group, all lower than the control group. The drug group also had higher immune protection rates than the control group. The results indicate that intraperitoneal injection of licorice extract can improve the immune function and disease resistance of giant salamanders to a certain extent. VL - 5 IS - 4 ER -
Department of Life Sciences, Xianyang Normal University, Xianyang, China; Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, People's Republic of China, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan, China; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan, China
Department of Life Sciences, Xianyang Normal University, Xianyang, China
Department of Life Sciences, Xianyang Normal University, Xianyang, China
Department of Life Sciences, Xianyang Normal University, Xianyang, China
Department of Life Sciences, Xianyang Normal University, Xianyang, China
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