Journal of Food and Nutrition Sciences

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Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women

Received: Aug. 02, 2019    Accepted: Aug. 24, 2019    Published: Sep. 19, 2019
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Abstract

Aim: Our previous study demonstrated that the ingestion of fructose with fat exacerbated and delayed postprandial lipid metabolism (J Atheroscler Thromb 2013; 20: 591). Herein, we investigated the effect of ingesting a water-soluble dietary fiber, resistant maltodextrin (RMD), which has been reported to be effective for ameliorating postprandial glycemia and lipidemia, on fructose-induced postprandial hyperlipidemia in healthy young women. Methods: Healthy young Japanese women with apolipoprotein E3/3 phenotype were enrolled. They underwent 4 test trials in a randomized crossover design: fat cream (0.35 g/kg of fat; F trial), fat cream with RMD (5 g; FR trial), fat cream with fructose (0.5 g/kg; FFr trial), and fat cream with fructose and RMD (FFrR trial). Blood samples were taken before (0) and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: The serum glucose and insulin concentrations peaked at 0.5 h in the FFr and FFrR trials, and no difference was observed between these trials. There was no increase in glucose concentration in the F or FR trials. The serum triglyceride and apolipoprotein B48 concentrations peaked at 4 h in all trials. In the F and FR trials (but not in the FFr and FFrR trials), the serum triglyceride concentration returned to the fasting level at 6 h. In all trials, the apolipoprotein B48 concentration did not return to baseline at 6 h. Conclusion: Co-ingestion of RMD did not significantly inhibit fructose-induced postprandial hyperlipidemia.

DOI 10.11648/j.jfns.20190703.12
Published in Journal of Food and Nutrition Sciences ( Volume 7, Issue 3, May 2019 )
Page(s) 49-55
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Resistant Maltodextrin, Fructose, Postprandial Hyperlipidemia, Triglyceride-Rich Lipoprotein, Remnant

References
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[2] Saito H, Kato M, Yoshida A, Naito M: The ingestion of a fructose-containing beverage combined with fat cream exacerbates postprandial lipidemia in young healthy women. J Atheroscler Thromb. 2015; 22: 85-94.
[3] Saito H, Kato M, Yoshida A, Naito M: The ingestion of high-fructose syrup-containing cola with a hamburger delays postprandial lipid metabolism in young healthy Japanese women. J Food Nutr Sci. 2015; 3: 139-146.
[4] Kato M, Yoshida A, Naito M: Fast food ingestion for lunch delays postprandial lipid metabolism in young women. J Food Nutr Sci. 2017; 5: 116-121.
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[6] Ohkuma K, Matsuda I, Katta Y, Hanno Y: Pyrolysis of starch and its digestibility by enzymes-characterization of resistant maltodextrin. J Jpn Soc Starch Sci. 1990; 37: 107-114 (In Japanese).
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[9] Fastinger ND, Karr-Lilienthal LK, Spears JK, Swanson KS, Zinn KE, Nava GM, Ohkuma K, Kanahori S, Gordon DT, Fahey GC Jr: A novel resistant maltodextrin alters gastrointestinal tolerance factors, fecal characteristics, and fecal microbiota in healthy adult humans. J Am Coll Nutr. 2008; 27: 356-366.
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[15] Aliasgharzadeh A, Dehghan P, Gargari BP, Asghari-Jafarabadi M: Resistant dextrin, as a prebiotic, improves insulin resistance and inflammation in women with type 2 diabetes: a randomised controlled clinical trial. Br J Nutr. 2015; 113: 321-330.
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  • APA Style

    Kaori Kuzawa, Akihiro Yoshida, Ikuko Tsukamoto, Masaaki Tokuda, Michitaka Naito. (2019). Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women. Journal of Food and Nutrition Sciences, 7(3), 49-55. https://doi.org/10.11648/j.jfns.20190703.12

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    ACS Style

    Kaori Kuzawa; Akihiro Yoshida; Ikuko Tsukamoto; Masaaki Tokuda; Michitaka Naito. Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women. J. Food Nutr. Sci. 2019, 7(3), 49-55. doi: 10.11648/j.jfns.20190703.12

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    AMA Style

    Kaori Kuzawa, Akihiro Yoshida, Ikuko Tsukamoto, Masaaki Tokuda, Michitaka Naito. Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women. J Food Nutr Sci. 2019;7(3):49-55. doi: 10.11648/j.jfns.20190703.12

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  • @article{10.11648/j.jfns.20190703.12,
      author = {Kaori Kuzawa and Akihiro Yoshida and Ikuko Tsukamoto and Masaaki Tokuda and Michitaka Naito},
      title = {Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women},
      journal = {Journal of Food and Nutrition Sciences},
      volume = {7},
      number = {3},
      pages = {49-55},
      doi = {10.11648/j.jfns.20190703.12},
      url = {https://doi.org/10.11648/j.jfns.20190703.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.jfns.20190703.12},
      abstract = {Aim: Our previous study demonstrated that the ingestion of fructose with fat exacerbated and delayed postprandial lipid metabolism (J Atheroscler Thromb 2013; 20: 591). Herein, we investigated the effect of ingesting a water-soluble dietary fiber, resistant maltodextrin (RMD), which has been reported to be effective for ameliorating postprandial glycemia and lipidemia, on fructose-induced postprandial hyperlipidemia in healthy young women. Methods: Healthy young Japanese women with apolipoprotein E3/3 phenotype were enrolled. They underwent 4 test trials in a randomized crossover design: fat cream (0.35 g/kg of fat; F trial), fat cream with RMD (5 g; FR trial), fat cream with fructose (0.5 g/kg; FFr trial), and fat cream with fructose and RMD (FFrR trial). Blood samples were taken before (0) and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: The serum glucose and insulin concentrations peaked at 0.5 h in the FFr and FFrR trials, and no difference was observed between these trials. There was no increase in glucose concentration in the F or FR trials. The serum triglyceride and apolipoprotein B48 concentrations peaked at 4 h in all trials. In the F and FR trials (but not in the FFr and FFrR trials), the serum triglyceride concentration returned to the fasting level at 6 h. In all trials, the apolipoprotein B48 concentration did not return to baseline at 6 h. Conclusion: Co-ingestion of RMD did not significantly inhibit fructose-induced postprandial hyperlipidemia.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women
    AU  - Kaori Kuzawa
    AU  - Akihiro Yoshida
    AU  - Ikuko Tsukamoto
    AU  - Masaaki Tokuda
    AU  - Michitaka Naito
    Y1  - 2019/09/19
    PY  - 2019
    N1  - https://doi.org/10.11648/j.jfns.20190703.12
    DO  - 10.11648/j.jfns.20190703.12
    T2  - Journal of Food and Nutrition Sciences
    JF  - Journal of Food and Nutrition Sciences
    JO  - Journal of Food and Nutrition Sciences
    SP  - 49
    EP  - 55
    PB  - Science Publishing Group
    SN  - 2330-7293
    UR  - https://doi.org/10.11648/j.jfns.20190703.12
    AB  - Aim: Our previous study demonstrated that the ingestion of fructose with fat exacerbated and delayed postprandial lipid metabolism (J Atheroscler Thromb 2013; 20: 591). Herein, we investigated the effect of ingesting a water-soluble dietary fiber, resistant maltodextrin (RMD), which has been reported to be effective for ameliorating postprandial glycemia and lipidemia, on fructose-induced postprandial hyperlipidemia in healthy young women. Methods: Healthy young Japanese women with apolipoprotein E3/3 phenotype were enrolled. They underwent 4 test trials in a randomized crossover design: fat cream (0.35 g/kg of fat; F trial), fat cream with RMD (5 g; FR trial), fat cream with fructose (0.5 g/kg; FFr trial), and fat cream with fructose and RMD (FFrR trial). Blood samples were taken before (0) and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: The serum glucose and insulin concentrations peaked at 0.5 h in the FFr and FFrR trials, and no difference was observed between these trials. There was no increase in glucose concentration in the F or FR trials. The serum triglyceride and apolipoprotein B48 concentrations peaked at 4 h in all trials. In the F and FR trials (but not in the FFr and FFrR trials), the serum triglyceride concentration returned to the fasting level at 6 h. In all trials, the apolipoprotein B48 concentration did not return to baseline at 6 h. Conclusion: Co-ingestion of RMD did not significantly inhibit fructose-induced postprandial hyperlipidemia.
    VL  - 7
    IS  - 3
    ER  - 

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Author Information
  • Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan

  • Department of Clinical Laboratory, Sakashita Hospital, Nakatsugawa, Japan

  • Faculty of Medicine, Kagawa University, Miki, Japan

  • Faculty of Medicine, Kagawa University, Miki, Japan

  • Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan

  • Section