American Journal of Clinical and Experimental Medicine

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The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain

Received: Jan. 31, 2020    Accepted: Feb. 18, 2020    Published: Feb. 26, 2020
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Abstract

To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (P<0.05). The predictive ROC curve area of GRACE scores in 30-day MACE was 0.739 (0.687 to 0.791). The probability of 30-day cardiovascular adverse events in various GRACE score risk stratification was 2.0% (low-risk), 5.33% (medium-risk), and 9.67% (high-risk), respectively. The GRACE score was a useful predictor to the occurrence of 30-day cardiovascular adverse events in acute chest pain patients. Patients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.

DOI 10.11648/j.ajcem.20200801.11
Published in American Journal of Clinical and Experimental Medicine ( Volume 8, Issue 1, January 2020 )
Page(s) 1-5
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

GRACE Scores, Acute Chest Pain, Risk Stratification, Cardiovascular Adverse Events

References
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    Zhenhua Huang, Qianlin Gu, Hong Zhan, Zhen Yang, Yuee Chen. (2020). The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. American Journal of Clinical and Experimental Medicine, 8(1), 1-5. https://doi.org/10.11648/j.ajcem.20200801.11

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    ACS Style

    Zhenhua Huang; Qianlin Gu; Hong Zhan; Zhen Yang; Yuee Chen. The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. Am. J. Clin. Exp. Med. 2020, 8(1), 1-5. doi: 10.11648/j.ajcem.20200801.11

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    AMA Style

    Zhenhua Huang, Qianlin Gu, Hong Zhan, Zhen Yang, Yuee Chen. The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. Am J Clin Exp Med. 2020;8(1):1-5. doi: 10.11648/j.ajcem.20200801.11

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  • @article{10.11648/j.ajcem.20200801.11,
      author = {Zhenhua Huang and Qianlin Gu and Hong Zhan and Zhen Yang and Yuee Chen},
      title = {The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain},
      journal = {American Journal of Clinical and Experimental Medicine},
      volume = {8},
      number = {1},
      pages = {1-5},
      doi = {10.11648/j.ajcem.20200801.11},
      url = {https://doi.org/10.11648/j.ajcem.20200801.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajcem.20200801.11},
      abstract = {To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (PPatients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.},
     year = {2020}
    }
    

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    AU  - Zhenhua Huang
    AU  - Qianlin Gu
    AU  - Hong Zhan
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    DO  - 10.11648/j.ajcem.20200801.11
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    JO  - American Journal of Clinical and Experimental Medicine
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    UR  - https://doi.org/10.11648/j.ajcem.20200801.11
    AB  - To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (PPatients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.
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Author Information
  • Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China

  • Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China

  • Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China

  • Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China

  • Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China

  • Section