International Journal of Infectious Diseases and Therapy

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Pattern of Childhood Tuberculosis in the Outpatient Department of a Tertiary Level Hospital in Dhaka City

Received: Mar. 22, 2020    Accepted: Apr. 09, 2020    Published: May 15, 2020
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Abstract

Introduction: Tuberculosis (TB) in children is increasingly becoming an important cause of global child morbidity and mortality. Objective: The objective of this study was to evaluate the clinical spectrum of TB in children under the age of 15 years and document any changes that occur over time. Materials & Methods: This observational study was conducted in the pediatric outpatient department (OPD) of 250 Bedded TB Hospital, Shyamoli, Dhaka, from October’2016 to January’2017. A total 71 children of both sex up to 15 years of age, who were diagnosed as having TB and attended the pediatric OPD of TB hospital during the four months study period were enrolled. The data was analyzed on the basis of patient’s age, gender, socioeconomic status, mode of presentation, BCG vaccination status, history of contact with smear positive TB patient, clinical findings, investigations and associated co-morbidities. Results: This study revealed that among the 71 cases of TB, (72%) had extra-pulmonary TB (EPTB) and (28%) had pulmonary TB (PTB), the commonest age group was 6 to 15 years with male preponderance (51%). Pulmonary TB was diagnosed mostly clinically (60%) followed by positive sputum smear result (20%), gastric aspirate for acid-fast bacilli AFB (5%) and sputum for Gene Xpert (5%). Distribution of extra-pulmonary TB (EPTB) according to the organ involvement was TB lymphadenitis (49%), osteoarticular TB (19.6%) and abdominal TB (5.9%). Cervical lymphadenopathy was the commonest presentation (76%) among the EPTB cases. Tuberculin skin test (TST) was positive in (69%) cases. Among the total cases (90%) children had TB alone whereas (10%) had other co-morbid disease along with TB. Conclusion: Extra-pulmonary TB (EPTB) was more prevalent among the childhood TB cases in a tertiary level set up where cervical TB lymphadenitis was the commonest.

DOI 10.11648/j.ijidt.20200502.11
Published in International Journal of Infectious Diseases and Therapy ( Volume 5, Issue 2, June 2020 )
Page(s) 23-28
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Childhood TB, Pulmonary TB, Extra-pulmonary TB

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Cite This Article
  • APA Style

    Md. Mozammel Haque, Md. Abdullah-Al-Maruf, Abdullah Al Baki, A. Z. M. Motiur Rahman, Md. Arif Rabbany, et al. (2020). Pattern of Childhood Tuberculosis in the Outpatient Department of a Tertiary Level Hospital in Dhaka City. International Journal of Infectious Diseases and Therapy, 5(2), 23-28. https://doi.org/10.11648/j.ijidt.20200502.11

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    ACS Style

    Md. Mozammel Haque; Md. Abdullah-Al-Maruf; Abdullah Al Baki; A. Z. M. Motiur Rahman; Md. Arif Rabbany, et al. Pattern of Childhood Tuberculosis in the Outpatient Department of a Tertiary Level Hospital in Dhaka City. Int. J. Infect. Dis. Ther. 2020, 5(2), 23-28. doi: 10.11648/j.ijidt.20200502.11

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    AMA Style

    Md. Mozammel Haque, Md. Abdullah-Al-Maruf, Abdullah Al Baki, A. Z. M. Motiur Rahman, Md. Arif Rabbany, et al. Pattern of Childhood Tuberculosis in the Outpatient Department of a Tertiary Level Hospital in Dhaka City. Int J Infect Dis Ther. 2020;5(2):23-28. doi: 10.11648/j.ijidt.20200502.11

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  • @article{10.11648/j.ijidt.20200502.11,
      author = {Md. Mozammel Haque and Md. Abdullah-Al-Maruf and Abdullah Al Baki and A. Z. M. Motiur Rahman and Md. Arif Rabbany and Dhiman Chowdhury and Muhammad Jabed Bin Amin Chowdhury and Muhammad Ismail Hasan and Mohammad Morshad Alam and Jugindra Singha and Md. Shohidul Islam Khan and Md. Humayan Kabir and Mohammed Golam Mowla and Kamrunnaher Shultana},
      title = {Pattern of Childhood Tuberculosis in the Outpatient Department of a Tertiary Level Hospital in Dhaka City},
      journal = {International Journal of Infectious Diseases and Therapy},
      volume = {5},
      number = {2},
      pages = {23-28},
      doi = {10.11648/j.ijidt.20200502.11},
      url = {https://doi.org/10.11648/j.ijidt.20200502.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijidt.20200502.11},
      abstract = {Introduction: Tuberculosis (TB) in children is increasingly becoming an important cause of global child morbidity and mortality. Objective: The objective of this study was to evaluate the clinical spectrum of TB in children under the age of 15 years and document any changes that occur over time. Materials & Methods: This observational study was conducted in the pediatric outpatient department (OPD) of 250 Bedded TB Hospital, Shyamoli, Dhaka, from October’2016 to January’2017. A total 71 children of both sex up to 15 years of age, who were diagnosed as having TB and attended the pediatric OPD of TB hospital during the four months study period were enrolled. The data was analyzed on the basis of patient’s age, gender, socioeconomic status, mode of presentation, BCG vaccination status, history of contact with smear positive TB patient, clinical findings, investigations and associated co-morbidities. Results: This study revealed that among the 71 cases of TB, (72%) had extra-pulmonary TB (EPTB) and (28%) had pulmonary TB (PTB), the commonest age group was 6 to 15 years with male preponderance (51%). Pulmonary TB was diagnosed mostly clinically (60%) followed by positive sputum smear result (20%), gastric aspirate for acid-fast bacilli AFB (5%) and sputum for Gene Xpert (5%). Distribution of extra-pulmonary TB (EPTB) according to the organ involvement was TB lymphadenitis (49%), osteoarticular TB (19.6%) and abdominal TB (5.9%). Cervical lymphadenopathy was the commonest presentation (76%) among the EPTB cases. Tuberculin skin test (TST) was positive in (69%) cases. Among the total cases (90%) children had TB alone whereas (10%) had other co-morbid disease along with TB. Conclusion: Extra-pulmonary TB (EPTB) was more prevalent among the childhood TB cases in a tertiary level set up where cervical TB lymphadenitis was the commonest.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Pattern of Childhood Tuberculosis in the Outpatient Department of a Tertiary Level Hospital in Dhaka City
    AU  - Md. Mozammel Haque
    AU  - Md. Abdullah-Al-Maruf
    AU  - Abdullah Al Baki
    AU  - A. Z. M. Motiur Rahman
    AU  - Md. Arif Rabbany
    AU  - Dhiman Chowdhury
    AU  - Muhammad Jabed Bin Amin Chowdhury
    AU  - Muhammad Ismail Hasan
    AU  - Mohammad Morshad Alam
    AU  - Jugindra Singha
    AU  - Md. Shohidul Islam Khan
    AU  - Md. Humayan Kabir
    AU  - Mohammed Golam Mowla
    AU  - Kamrunnaher Shultana
    Y1  - 2020/05/15
    PY  - 2020
    N1  - https://doi.org/10.11648/j.ijidt.20200502.11
    DO  - 10.11648/j.ijidt.20200502.11
    T2  - International Journal of Infectious Diseases and Therapy
    JF  - International Journal of Infectious Diseases and Therapy
    JO  - International Journal of Infectious Diseases and Therapy
    SP  - 23
    EP  - 28
    PB  - Science Publishing Group
    SN  - 2578-966X
    UR  - https://doi.org/10.11648/j.ijidt.20200502.11
    AB  - Introduction: Tuberculosis (TB) in children is increasingly becoming an important cause of global child morbidity and mortality. Objective: The objective of this study was to evaluate the clinical spectrum of TB in children under the age of 15 years and document any changes that occur over time. Materials & Methods: This observational study was conducted in the pediatric outpatient department (OPD) of 250 Bedded TB Hospital, Shyamoli, Dhaka, from October’2016 to January’2017. A total 71 children of both sex up to 15 years of age, who were diagnosed as having TB and attended the pediatric OPD of TB hospital during the four months study period were enrolled. The data was analyzed on the basis of patient’s age, gender, socioeconomic status, mode of presentation, BCG vaccination status, history of contact with smear positive TB patient, clinical findings, investigations and associated co-morbidities. Results: This study revealed that among the 71 cases of TB, (72%) had extra-pulmonary TB (EPTB) and (28%) had pulmonary TB (PTB), the commonest age group was 6 to 15 years with male preponderance (51%). Pulmonary TB was diagnosed mostly clinically (60%) followed by positive sputum smear result (20%), gastric aspirate for acid-fast bacilli AFB (5%) and sputum for Gene Xpert (5%). Distribution of extra-pulmonary TB (EPTB) according to the organ involvement was TB lymphadenitis (49%), osteoarticular TB (19.6%) and abdominal TB (5.9%). Cervical lymphadenopathy was the commonest presentation (76%) among the EPTB cases. Tuberculin skin test (TST) was positive in (69%) cases. Among the total cases (90%) children had TB alone whereas (10%) had other co-morbid disease along with TB. Conclusion: Extra-pulmonary TB (EPTB) was more prevalent among the childhood TB cases in a tertiary level set up where cervical TB lymphadenitis was the commonest.
    VL  - 5
    IS  - 2
    ER  - 

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Author Information
  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Medicine, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics, Upazilla Health Complex, Sreepur, Gazipur, Bangladesh

  • Department of Pediatrics, Chattogram Medical College Hospital, Chattogram, Bangladesh

  • Department of Pediatrics, Chattogram Medical College Hospital, Chattogram, Bangladesh

  • Department of Pediatrics, Sadar Hospital, Laxmipur, Bangladesh

  • Department of Pediatrics, Sadar Hospital, Laxmipur, Bangladesh

  • Department of Pediatrics, Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh

  • Department of Pediatrics, Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh

  • Department of Pediatrics, Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh

  • Department of Pediatrics, Upazilla Health Complex, Muktagacha, Mymensingh

  • Department of Pediatrics and PICU, Square Hospitals Ltd., Dhaka, Bangladesh

  • Section