European Journal of Clinical and Biomedical Sciences

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Epidemiology and Risk Factor of the Gallstone Disease in a Southern Tropical Country

Received: Nov. 12, 2019    Accepted: Dec. 04, 2019    Published: Dec. 13, 2019
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Abstract

Despite the tendency to westernize our way of life, the Malagasy culture keeps its peculiarities. We report the epidemiological features of patients with cholelithiasis in our population in order to raise hypothesis about their risk factors. This is a retrospective descriptive multicenter and analytical case-control study of patients with cholelithiasis as "cases" and non-carriers of cholelithiasis as "controls". The odds ratios (ORs) were calculated with a 95% confidence interval to verify the correlation between food consumption and the occurrence of cholelithiasis. 51 patients were respectively enrolled for both groups. Consumption of animal products and legumes, such as offal (OR 95% CI 3.23-1.36-7.67), chicken (OR 95% CI 8.85 [3.02-25.9]), peas (OR 95% CI 1.13 [0.43 - 2.95]) and Bambara peas (OR 95% CI 1.31 [0.57 - 3.01 ]) would expose the risk of occurrence of cholelithiasis. In contrast, whole milk (OR 95% CI 1.27 [0.58 - 2.77]), sweet potato (OR 95% CI 0.72 [0.23 - 2.25]) and cassava (OR 95% CI 0.83 [0.36 - 1.92]) would be a protective factor. To conclude, the diversification of our fruits and vegetables could be an asset to reduce the frequency of occurrence of cholelithiasis, giving priority to their consumption.

DOI 10.11648/j.ejcbs.20190506.11
Published in European Journal of Clinical and Biomedical Sciences ( Volume 5, Issue 6, December 2019 )
Page(s) 73-78
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Epidemiology, Gallstones, Madagascar, Risk Factor

References
[1] European Association for the Study of the Liver (EASL). Recommandations de Pratique Clinique sur la prévention, le diagnostic et le traitement des calculs biliaires selon l’EASL. Journal of Hepatology. 2016; 65: 146–81.
[2] Sanlorenzo M, Caldera D, Randriamitantsoa S,. Rakotondrajao J, Razanadranaivo F. La lithiase biliaire dans le Sud de Madagascar. Médecine d'Afrique Noire. 1993, 40 (10): 585–588.
[3] Cariati A, Piromalli E, Cetta F. Gallbladder cancers: associated conditions, histological types, prognosis, and prevention. Eur J Gastroenterol Hepatol. 2014; 26: 562–569.
[4] Jain K, Mohapatra T, Das P, Misra MC, Gupta SD, Ghosh M, et al. Sequential occurrence of preneoplastic lesions and accumulation of loss of heterozygosity in patients with gallbladder stones suggest causal association with gallbladder cancer. Ann Surg. 2014; 260: 1073–1080.
[5] Payen J-L, Muscari F, Vibert E, Ernst O, Pelletier G. Lithiase biliaire. Presse Med. 2011; 40: 567–80.
[6] Schirmer BD, Winters KL, Edlich RF. Cholelithiasis and cholecystitis. J Long Term Eff Med Implants. 2005; 15 (3): 329-38.
[7] Di Ciaula A, Wang DQ, Portincasa P. An update on the pathogenesis of cholesterol gallstone disease. Curr Opin Gastroenterol 2018; 34: 71–80.
[8] Zhang J-W, Xiong J-P, Xu W-Y, Sang X-T, Huang H-C, Bian J, et al. Fruits and vegetables consumption and the risk of gallstone diasease. A systematic review and meta-analysis. Medicine. 2019; 98: 28-37.
[9] Chang C-M, Chiu THT, Chang C-C, Lin M-N, Lin C-L. Plant-Based Diet, Cholesterol, and Risk of Gallstone Disease: A Prospective Study. Nutrients. 2019; 11: 335 – 48.
[10] Delabrousse E, Di Martino V, Aubry S, Fein F, Sarliève P, Carbonnel F, et al. The choledochal ring sign: a specific finding in acute biliary pancreatitis. Abd Imaging. 2008; 33; 3: 337–4.
[11] Stinton LM, Myers RP, Shaffer EA. Epidemiology of gallstones. Gastroenterol Clin North Am. 2010; 39: 157–69.
[12] Brugère C, Slim K, Fritsch S. How to treat common bile duct stones? Ann Chir. 2005; 130: 175–7.
[13] Ko CW, Lee SP. Role of ERCP in gallstone, Epidemiology and natural history of common bile duct stones and prediction of disease. Gastroenterology. 2002; 56; 6: 165–9.
[14] Maclure KM, Hayes KC, Colditz GA, Stampfer MJ, Speizer FE, Willett WC. Weight, diet, and the risk of symptomatic gallstones in middle-aged women. N Engl J Med. 1989; 321: 563–69.
[15] Hussain I, Ahmed HA. Hepatobiliary Manifestations of Sickle Cell Anemia. Gastroenterol Res. 2010; 3; 1: 1–8.
[16] Etminan M, Delaney JA, Bressler B, Brophy JM. Oral contraceptives and the risk of gallbladder disease: a comparative safety study. CMAJ. 2011; 183: 899–904.
[17] Leitzmann MF, Tsai CJ, Stampfer MJ, Rimm EB, Colditz GA, Willett WC, et al. Alcohol consumption in relation to risk of cholecystectomy in women. Am J Clin Nutr. 2003; 78: 339–347.
[18] Carvalho RB, Nobre RS, Guimarães MR, Teixeira SE, Silva AR. Risk factor associated with the development of metabolic syndrome in children and adolescents. Acta Paul Enferm. 2016; 29; 4: 439–45.
[19] Yamada M, Wong FL, Fujiwara S, Tatsukawa Y, Suzuki G. Smoking and alcohol habits as risk factors for benign digestive diseases in a Japanese population: the radiation effects research foundation adult health study. Digestion. 2005; 71: 231–7.
[20] Ansari-Moghaddam A, Khorram A, Miri-Bonjar M, Mohammadi M, Ansari. The prevalence and risk factors of gallstone among adults in South-East of Iran: A population-based study. J Health Sc. 2016; 8; 4: 60–6.
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  • APA Style

    Solonirina Davidà Rakotomena, Sedera Arimino, Finaritra Casimir Fleur Prudence Rahantasoa, Antso Hasina Raherinandrasana, Tianarivelo Rajaonarivony, et al. (2019). Epidemiology and Risk Factor of the Gallstone Disease in a Southern Tropical Country. European Journal of Clinical and Biomedical Sciences, 5(6), 73-78. https://doi.org/10.11648/j.ejcbs.20190506.11

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    ACS Style

    Solonirina Davidà Rakotomena; Sedera Arimino; Finaritra Casimir Fleur Prudence Rahantasoa; Antso Hasina Raherinandrasana; Tianarivelo Rajaonarivony, et al. Epidemiology and Risk Factor of the Gallstone Disease in a Southern Tropical Country. Eur. J. Clin. Biomed. Sci. 2019, 5(6), 73-78. doi: 10.11648/j.ejcbs.20190506.11

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    AMA Style

    Solonirina Davidà Rakotomena, Sedera Arimino, Finaritra Casimir Fleur Prudence Rahantasoa, Antso Hasina Raherinandrasana, Tianarivelo Rajaonarivony, et al. Epidemiology and Risk Factor of the Gallstone Disease in a Southern Tropical Country. Eur J Clin Biomed Sci. 2019;5(6):73-78. doi: 10.11648/j.ejcbs.20190506.11

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  • @article{10.11648/j.ejcbs.20190506.11,
      author = {Solonirina Davidà Rakotomena and Sedera Arimino and Finaritra Casimir Fleur Prudence Rahantasoa and Antso Hasina Raherinandrasana and Tianarivelo Rajaonarivony and Hery Nirina Rakoto Ratsimba},
      title = {Epidemiology and Risk Factor of the Gallstone Disease in a Southern Tropical Country},
      journal = {European Journal of Clinical and Biomedical Sciences},
      volume = {5},
      number = {6},
      pages = {73-78},
      doi = {10.11648/j.ejcbs.20190506.11},
      url = {https://doi.org/10.11648/j.ejcbs.20190506.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ejcbs.20190506.11},
      abstract = {Despite the tendency to westernize our way of life, the Malagasy culture keeps its peculiarities. We report the epidemiological features of patients with cholelithiasis in our population in order to raise hypothesis about their risk factors. This is a retrospective descriptive multicenter and analytical case-control study of patients with cholelithiasis as "cases" and non-carriers of cholelithiasis as "controls". The odds ratios (ORs) were calculated with a 95% confidence interval to verify the correlation between food consumption and the occurrence of cholelithiasis. 51 patients were respectively enrolled for both groups. Consumption of animal products and legumes, such as offal (OR 95% CI 3.23-1.36-7.67), chicken (OR 95% CI 8.85 [3.02-25.9]), peas (OR 95% CI 1.13 [0.43 - 2.95]) and Bambara peas (OR 95% CI 1.31 [0.57 - 3.01 ]) would expose the risk of occurrence of cholelithiasis. In contrast, whole milk (OR 95% CI 1.27 [0.58 - 2.77]), sweet potato (OR 95% CI 0.72 [0.23 - 2.25]) and cassava (OR 95% CI 0.83 [0.36 - 1.92]) would be a protective factor. To conclude, the diversification of our fruits and vegetables could be an asset to reduce the frequency of occurrence of cholelithiasis, giving priority to their consumption.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Epidemiology and Risk Factor of the Gallstone Disease in a Southern Tropical Country
    AU  - Solonirina Davidà Rakotomena
    AU  - Sedera Arimino
    AU  - Finaritra Casimir Fleur Prudence Rahantasoa
    AU  - Antso Hasina Raherinandrasana
    AU  - Tianarivelo Rajaonarivony
    AU  - Hery Nirina Rakoto Ratsimba
    Y1  - 2019/12/13
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ejcbs.20190506.11
    DO  - 10.11648/j.ejcbs.20190506.11
    T2  - European Journal of Clinical and Biomedical Sciences
    JF  - European Journal of Clinical and Biomedical Sciences
    JO  - European Journal of Clinical and Biomedical Sciences
    SP  - 73
    EP  - 78
    PB  - Science Publishing Group
    SN  - 2575-5005
    UR  - https://doi.org/10.11648/j.ejcbs.20190506.11
    AB  - Despite the tendency to westernize our way of life, the Malagasy culture keeps its peculiarities. We report the epidemiological features of patients with cholelithiasis in our population in order to raise hypothesis about their risk factors. This is a retrospective descriptive multicenter and analytical case-control study of patients with cholelithiasis as "cases" and non-carriers of cholelithiasis as "controls". The odds ratios (ORs) were calculated with a 95% confidence interval to verify the correlation between food consumption and the occurrence of cholelithiasis. 51 patients were respectively enrolled for both groups. Consumption of animal products and legumes, such as offal (OR 95% CI 3.23-1.36-7.67), chicken (OR 95% CI 8.85 [3.02-25.9]), peas (OR 95% CI 1.13 [0.43 - 2.95]) and Bambara peas (OR 95% CI 1.31 [0.57 - 3.01 ]) would expose the risk of occurrence of cholelithiasis. In contrast, whole milk (OR 95% CI 1.27 [0.58 - 2.77]), sweet potato (OR 95% CI 0.72 [0.23 - 2.25]) and cassava (OR 95% CI 0.83 [0.36 - 1.92]) would be a protective factor. To conclude, the diversification of our fruits and vegetables could be an asset to reduce the frequency of occurrence of cholelithiasis, giving priority to their consumption.
    VL  - 5
    IS  - 6
    ER  - 

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Author Information
  • Faculty of Medecine, Antananarivo, Madagascar

  • Faculty of Medecine, Antananarivo, Madagascar

  • Faculty of Medecine, Antananarivo, Madagascar

  • Faculty of Medecine, Antananarivo, Madagascar

  • Faculty of Medecine, Antananarivo, Madagascar

  • Faculty of Medecine, Antananarivo, Madagascar

  • Section