The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone

Mahmoud Abdel Aziz El Fadly; Heba Abdel Wahed Selim; Salah Abdel Fattah Ahmed

doi:doi:10.11648/j.ijcoms.20200602.11

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The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone

Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Selim, Salah Abdel Fattah Ahmed

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 6, Issue 2)

Received: 5 August 2019 Accepted: 9 September 2019 Published: 15 June 2020

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Abstract

The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.

Published in	International Journal of Clinical Oral and Maxillofacial Surgery (Volume 6, Issue 2)
DOI	10.11648/j.ijcoms.20200602.11
Page(s)	20-25
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Bone Marrow Concentrate, Autogenous Bone Graft, Nano-hydroxyapatite, Surgical Defects

References

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APA Style

Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Selim, Salah Abdel Fattah Ahmed. (2020). The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. International Journal of Clinical Oral and Maxillofacial Surgery, 6(2), 20-25. https://doi.org/10.11648/j.ijcoms.20200602.11

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ACS Style

Mahmoud Abdel Aziz El Fadly; Heba Abdel Wahed Selim; Salah Abdel Fattah Ahmed. The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. Int. J. Clin. Oral Maxillofac. Surg. 2020, 6(2), 20-25. doi: 10.11648/j.ijcoms.20200602.11

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AMA Style

Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Selim, Salah Abdel Fattah Ahmed. The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. Int J Clin Oral Maxillofac Surg. 2020;6(2):20-25. doi: 10.11648/j.ijcoms.20200602.11

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@article{10.11648/j.ijcoms.20200602.11,
  author = {Mahmoud Abdel Aziz El Fadly and Heba Abdel Wahed Selim and Salah Abdel Fattah Ahmed},
  title = {The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {6},
  number = {2},
  pages = {20-25},
  doi = {10.11648/j.ijcoms.20200602.11},
  url = {https://doi.org/10.11648/j.ijcoms.20200602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20200602.11},
  abstract = {The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.},
 year = {2020}
}

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TY  - JOUR
T1  - The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone
AU  - Mahmoud Abdel Aziz El Fadly
AU  - Heba Abdel Wahed Selim
AU  - Salah Abdel Fattah Ahmed
Y1  - 2020/06/15
PY  - 2020
N1  - https://doi.org/10.11648/j.ijcoms.20200602.11
DO  - 10.11648/j.ijcoms.20200602.11
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 20
EP  - 25
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20200602.11
AB  - The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.
VL  - 6
IS  - 2
ER  -

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Author Information

Mahmoud Abdel Aziz El Fadly

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt
Heba Abdel Wahed Selim

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt
Salah Abdel Fattah Ahmed

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt

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APA Style

Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Selim, Salah Abdel Fattah Ahmed. (2020). The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. International Journal of Clinical Oral and Maxillofacial Surgery, 6(2), 20-25. https://doi.org/10.11648/j.ijcoms.20200602.11

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ACS Style

Mahmoud Abdel Aziz El Fadly; Heba Abdel Wahed Selim; Salah Abdel Fattah Ahmed. The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. Int. J. Clin. Oral Maxillofac. Surg. 2020, 6(2), 20-25. doi: 10.11648/j.ijcoms.20200602.11

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AMA Style

Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Selim, Salah Abdel Fattah Ahmed. The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. Int J Clin Oral Maxillofac Surg. 2020;6(2):20-25. doi: 10.11648/j.ijcoms.20200602.11

Copy | Download

@article{10.11648/j.ijcoms.20200602.11,
  author = {Mahmoud Abdel Aziz El Fadly and Heba Abdel Wahed Selim and Salah Abdel Fattah Ahmed},
  title = {The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {6},
  number = {2},
  pages = {20-25},
  doi = {10.11648/j.ijcoms.20200602.11},
  url = {https://doi.org/10.11648/j.ijcoms.20200602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20200602.11},
  abstract = {The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone
AU  - Mahmoud Abdel Aziz El Fadly
AU  - Heba Abdel Wahed Selim
AU  - Salah Abdel Fattah Ahmed
Y1  - 2020/06/15
PY  - 2020
N1  - https://doi.org/10.11648/j.ijcoms.20200602.11
DO  - 10.11648/j.ijcoms.20200602.11
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 20
EP  - 25
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20200602.11
AB  - The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.
VL  - 6
IS  - 2
ER  -

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