DNA microarrays are technology that measure the expression level of thousands of genes at the same time. They need become avital tool for a good kind of biological experiments. one among the most common goals of polymer microarray experiments is to spot genes related to biological processes of interest. DNA Microarray is one such technology that allows the researchers to analyze and address problems that were once thought to be non traceable. This technology has scepter the scientific community to manage the elemental aspects underlining the expansion and development of life, additionally on explore the genetic causes of anomalies occurring within the functioning of organisms. Microarrays area unit vital as a result of they possess a large variety of genes and additionally owingto their transportable size. An important implication of the fundamental dogma of molecular biology is that there should be a strong association between the presence of a given protein in a cell and the presence of the mRNA sequence that is transcribed to build that protein. If a protein is active in a given cell, there should be a large number of copies of the mRNA sequence corresponding to that protein. Conversely, if a protein is not active in a cell, there should be few copies of the corresponding mRNA sequence. Thus, DNA microarrays attempt to evaluate the presence or absence of proteins in a cell and their relative abundance by measuring the relative abundance of the corresponding mRNA sequences. This review addresses the potential uses of DNA microarray technology, principle of the technology, its application and limitation of the technology.
| Published in | American Journal of Zoology (Volume 2, Issue 4) |
| DOI | 10.11648/j.ajz.20190204.11 |
| Page(s) | 44-50 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
DNA Microarray, Protein Microarray, Hybridization, cDNA
| [1] | Afshari CA. Perspective: microarray technology, seeing more than spots. Endocrinology. 2002143 (6): 1983-1989. |
| [2] | Beier M, Hoheisel JD. Production by quantitative photolithographic synthesis of individually quality checked DNA microarrays. Nucleic Acids Res. 2000; 28 (4): E11. |
| [3] | Brown PO, Botstein D. Exploring the new world of the genome with DNA microarrays. Nat. |
| [4] | Bumgarner R. 2013. DNA microarrays: Types, Applications and their future. Current Protocols in Molecular Biology J 22-1 Chee M, Yang R, Hubbell E, Berno A, Huang XC, Stern D, Winkler J, Lockhart DJ, Morris MS, Fodor SP. 1996. Accessing genetic information with highdensity DNA arrays. Science J 274: 610–614. |
| [5] | Cao B; Yao F; Liu X; Feng L; Wang L. Development of a DNA Microarray Method for Detection and Identification of All 15 Distinct O-Antigen Forms of Legionella pneumophila. Applied and Environmental Microbiology. 79 (21), 6647-4454 (2013). doi: 10.1128/AEM.0195713. |
| [6] | Chen JJ, Wu R, Yang PC, Huang JY, Sher YP, Han MH, et al. (1998). Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection. Genomics 51: 313-324. |
| [7] | Crameri, A., J. Marfurt, K. Mugittu, N. Maire, A. Regos, J. Y. Coppee, O. Sismeiro, R. Burki, E. Huber, D. Laubscher, O. Puijalon, B. Genton, I. Felger, and H. P. Beck. 2007. Rapid microarray-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria drugs. J. Clin. Microbiol. 45: 3685–3691. |
| [8] | Gardina PJ, Clark TA, Shimada B, Staples MK, Yang Q, Veitch J, Schweitzer A, Awad T, Sugnet C, Dee S, Davies C, Williams A, Turpaz Y. Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array. BMC Genomics. 2006; 8: 325. [PubMed: 17192196]. |
| [9] | Gibson G. Microarrays in ecology and evolution: a preview. Mol Ecol. 2002; 11 (1): 17-24. |
| [10] | Gryadunov, D., V. Mikhailovich, S. Lapa, N. Roudinskii, M. Donnikov, S. Pan’kov, O. Markova, A. Kuz’min, L. Chernousova, O. Skotnikova, A. Moroz, A. Zasedatelev, and A. Mirzabekov. 2005. Evaluation of hybridisation on oligonucleotide microarrays for analysis of drug. |
| [11] | Guo L, Liu Y, Bai Y, Sun Y, Xiao F, Guo Y. Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis. Eur J Cancer. 2010; 46 (9): 1692-1702. |
| [12] | Hall DA, Ptacek J, Snyder M. Protein microarray technology. Mech Ageing Dev. 2007; 128 (1): 161-167. |
| [13] | Han J, Yoo HY, Choi BH, Rho HM (2000). Selective transcriptional regulations in the human liver cell by hepatitis B viral X protein. BiochemBiophys Res Commun 272: 525-530. |
| [14] | Khademhosseini A; Suh K; Zourob M. Biological Microarrays: Methods and Protocols. New York: Humana Press. (2011). |
| [15] | Kittichotirat W, Bumgarner RE, Asikainen S, Chen C. Identification of the pangenome and its components in 14 distinct Aggregatibacteractinomycetemcomitans strains by comparative genomic analysis. PLoS ONE. 2011; 6: e22420. [PubMed: 21811606]. |
| [16] | Klein JC; Lajoie MJ; Schwartz JJ; Strauch EM; Nelson J; Baker D. Multiplex Pairwise Assembly of Array-Derived DNA Oligonucleotides. Nucleic Acids Research. 44 (5), 1-10 (2016). doi: 10.1093/nar/gkv128. |
| [17] | K. R. Everett, J. Rees-George, I. P. S. Pushparajah, B. J. Janssen and Z. Luo.210Advantages and disadvantages of microarrays to study microbial population dynamics a minireview. 63: 1-6. |
| [18] | Kuo WP, Whipple ME, Jenssen TK, Todd R, Epstein JB, Ohno-Machado L, Sonis ST, Park P 15. Kodadek T. Protein microarrays: prospects and problems. Chem Biol. 2001; 8 (2): 105-115. Microarrays and clinical dentistry. J Am Dent Assoc. 2003; 134 (4): 456-462. |
| [19] | Lopez, M. F., and M. G. Pluskal. 2003. Protein micro- and macroarrays: digitizing the proteome. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 787: 19–27. |
| [20] | Mac Beath, G. 2002. Protein microarrays and proteomics. Nat. Genet. 32: 526–532. |
| [21] | Ma YY, Zhang XM. 2004. Application of DNA microarray technology in immunological research and its inspiration to researches on traditional Chinese medicine. Zhong Xi Yi Jie He XueBao= Chinese integrative medicine J 2 (2): 90-3. |
| [22] | Miller MB; Tang YW. Basic Concepts of Microarrays and Potential Applications in Clinical Microbiology. Clinical Microbiology Reviews. 22 (4), 611-633 (2009). doi: 10.1128/CMR.00019-09. |
| [23] | Pease AC, Solas D, Sullivan EJ, Cronin MT, Holmes CP, Fodor SP. Lightgenerated oligonucleotide arrays for rapid DNA sequence analysis. Proc Natl AcadSci USA. 1994; 91 (11): 5022–6. |
| [24] | Podder M; Ruan J; Tripp BW; Chu ZE; Tebbutt SJ. Robust SNP Genotyping by Multiplex PCR and Arrayed Primer Extension. BMC Medical Genomics. 1, 5 (2008). doi: 10.1186/1755-8794-1-5. |
| [25] | Pulverer W; Noehammer C; Vierlinger K; Weinhaeusel A. Principles and Application of Microarray Technology in Thyroid Cancer Research. Updates in the Understanding and Management of Thyroid Cancer. (2012). doi: 10.5772/27894. |
| [26] | Rao AN; Grainger DW. Biophysical Properties of Nucleic Acids At Surfaces Relevant To Microarray Performance. Biomater Sciences. 2 (4), 436-471 (2014). doi: 10.1039/C3BM60181A. |
| [27] | Robert P. Loewe; Peter J. Nelson.2011 Microarray Bioinformatics. Methods in Molecular Biology (Methods and Protocols). 671: 295-320. |
| [28] | Roman, I. 2008. DNA microarrays--perspective of application for drug effectivity and safety evaluation. Postepybiochemii J 54 (1): 107-115. |
| [29] | Rungroj N; Nettuwakul C; Sudtachat N; Praditsap O; Sawasdee N; Sritippayawan S; Chuawattana D; Yenchitsomanus P. A Whole Genome SNP Genotyping by DNA Microarray and Candidate Gene Association Study For Kidney Stone Disease. BMC Medical Genetics. 15 (50), 1-11 (2014). doi: 10.1186/1471-2350-15-50. |
| [30] | Russell Steve, Meadows Lisa A., and R. Russell Roslin. Microarray Technology in Practice. Elsevier Inc., 2008. |
| [31] | Saei Aa; Omidi Y. A Glance at DNA Microarray Technology and Applications. Bio Impacts: BI. 1] (2): 75-86 (2011). doi: 10.5681/bi.2011.011. |
| [32] | Schena M, Heller RA, Theriault TP, Konrad K, Lachenmeier E, Davis RW. Microarrays: biotechnology's discovery platform for functional genomics. Trends Biotechnol. 1998; 16 (7): 301-306. |
| [33] | Schnee C; Schulsse S; Hotzel H; Ayling RD; Nicholas RAJ; Schubert E.(2012). A Novel Rapid DNA Microarray Assay Enables Identification of 37 Mycoplasma Species and Highlights Multiple Mycoplasma Infections. PloSOne. 7 (3), e33237 (2012). doi: 10.1371/journal.pone.0033237. |
| [34] | Schrijver I; Külm M; Gardner PI; Pergament EP; Fiddler MB. Comprehensive Arrayed Primer Extension Array for the Detection of 59 Sequence Variants in 15 Conditions Prevalent Among the (Ashkenazi) Jewish Population. The Journal of molecular diagnostics: JMD. 9 (2), 228-236 (2007). doi: 10.2353/jmoldx.2007.060100. |
| [35] | Simon Gillespie. 2016 in Molecular Microbial Diagnostic Methods. 1: 262. |
| [36] | Svensen N; Diaz-Mocho JJ; Bradley M. Microarray Generation of Thousand-Member Oligonucleotide Libraries. PloSOne. 6 (9), e24906 (2011). doi: 10.1371/journal.pone.0024906. |
| [37] | Tillib SV, Mirzabekov AD. Advances in the analysis of DNA sequence variations using oligonucleotide microchip technology. CurrOpinBiotechnol. 2001; 12 (1): 53-58. |
| [38] | Trost B; Moir CA; Gillespie ZE; Kusalik A; Mitchell JA; Eskiw CH. Concordance Between RNA-Sequencing Data And DNA Microarray Data In Transcriptome Analysis of Proliferative and Quiescent Fibroblasts. Royal Society Open Science. 2, 150402 (2015). doi: 40.1098/rsos.150402. |
| [39] | Trumbić Z; Bekaert M; Taggart JB; Bron JE; Gharbi K; Mladineo I. Development And Validation of A Mixed-Tissue Oligonucleotide DNA Microarray For Atlantic Bluefin tuna, Thunnusthynnus (Linnaeus, 1758). BMC Genomics. 16 (1007), 1-17 (2015). doi: 10.1186/s12864-015-2208-7. |
| [40] | Victor Trevino, Francesco Falciani, and Hugo A Barrera-Saldaña. Dna microarrays: a powerful genomic tool for biomedical and clinical research. Mol Med, 13 (9-10): 527–41, 2007. |
| [41] | Zhu, L.-X., Z.-W. Zhang, D. Liang, D. Jiang, C. Wang, N. Du, Q. Zhang, K. Mitchelson, and J. Cheng. 2007. Multiplex asymmetric PCR-based oligonucleotide microarray for detection of drug resistance genes containing single mutations in Enterobacteriaceae. Antimicrob. AgentsChemother. 51: 3707–3713. |
APA Style
Takale Worku, Demessa Negassu. (2020). Review on DNA Micro Array Technologyand Its Application. American Journal of Zoology, 2(4), 44-50. https://doi.org/10.11648/j.ajz.20190204.11
ACS Style
Takale Worku; Demessa Negassu. Review on DNA Micro Array Technologyand Its Application. Am. J. Zool. 2020, 2(4), 44-50. doi: 10.11648/j.ajz.20190204.11
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ajz.20190204.11,
author = {Takale Worku and Demessa Negassu},
title = {Review on DNA Micro Array Technologyand Its Application},
journal = {American Journal of Zoology},
volume = {2},
number = {4},
pages = {44-50},
doi = {10.11648/j.ajz.20190204.11},
url = {https://doi.org/10.11648/j.ajz.20190204.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajz.20190204.11},
abstract = {DNA microarrays are technology that measure the expression level of thousands of genes at the same time. They need become avital tool for a good kind of biological experiments. one among the most common goals of polymer microarray experiments is to spot genes related to biological processes of interest. DNA Microarray is one such technology that allows the researchers to analyze and address problems that were once thought to be non traceable. This technology has scepter the scientific community to manage the elemental aspects underlining the expansion and development of life, additionally on explore the genetic causes of anomalies occurring within the functioning of organisms. Microarrays area unit vital as a result of they possess a large variety of genes and additionally owingto their transportable size. An important implication of the fundamental dogma of molecular biology is that there should be a strong association between the presence of a given protein in a cell and the presence of the mRNA sequence that is transcribed to build that protein. If a protein is active in a given cell, there should be a large number of copies of the mRNA sequence corresponding to that protein. Conversely, if a protein is not active in a cell, there should be few copies of the corresponding mRNA sequence. Thus, DNA microarrays attempt to evaluate the presence or absence of proteins in a cell and their relative abundance by measuring the relative abundance of the corresponding mRNA sequences. This review addresses the potential uses of DNA microarray technology, principle of the technology, its application and limitation of the technology.},
year = {2020}
}
TY - JOUR T1 - Review on DNA Micro Array Technologyand Its Application AU - Takale Worku AU - Demessa Negassu Y1 - 2020/01/06 PY - 2020 N1 - https://doi.org/10.11648/j.ajz.20190204.11 DO - 10.11648/j.ajz.20190204.11 T2 - American Journal of Zoology JF - American Journal of Zoology JO - American Journal of Zoology SP - 44 EP - 50 PB - Science Publishing Group SN - 2994-7413 UR - https://doi.org/10.11648/j.ajz.20190204.11 AB - DNA microarrays are technology that measure the expression level of thousands of genes at the same time. They need become avital tool for a good kind of biological experiments. one among the most common goals of polymer microarray experiments is to spot genes related to biological processes of interest. DNA Microarray is one such technology that allows the researchers to analyze and address problems that were once thought to be non traceable. This technology has scepter the scientific community to manage the elemental aspects underlining the expansion and development of life, additionally on explore the genetic causes of anomalies occurring within the functioning of organisms. Microarrays area unit vital as a result of they possess a large variety of genes and additionally owingto their transportable size. An important implication of the fundamental dogma of molecular biology is that there should be a strong association between the presence of a given protein in a cell and the presence of the mRNA sequence that is transcribed to build that protein. If a protein is active in a given cell, there should be a large number of copies of the mRNA sequence corresponding to that protein. Conversely, if a protein is not active in a cell, there should be few copies of the corresponding mRNA sequence. Thus, DNA microarrays attempt to evaluate the presence or absence of proteins in a cell and their relative abundance by measuring the relative abundance of the corresponding mRNA sequences. This review addresses the potential uses of DNA microarray technology, principle of the technology, its application and limitation of the technology. VL - 2 IS - 4 ER -
Information
Email: