American Journal of BioScience

Special Issue

Chemical Biology

  • Submission Deadline: 31 October 2014
  • Status: Submission Closed
  • Lead Guest Editor: Michael Ioelovich
About This Special Issue
Chemical Biology is a research field that aims at the synthesis of biologically active molecules and the analysis of their induced phenotypes. Chemical Biology is providing new tools for deciphering protein modification and activity. Designing small molecules as probes of protein and cellular function are becoming the method of choice for careful profiling and development of biological processes in areas such as drug discovery, neurochemistry and molecular genetics. Chemical Biology studies also include aging, microfluidics, neurodegenerative diseases, human immunodeficiency virus and drug development. Chemical biology new technologies may accelerate the discovery of still elusive cures to neurodegenerative diseases. This issue is intended for more research and discussion on chemical biology and its application and benefits to human health.
Lead Guest Editor
  • Michael Ioelovich

    Department of Biological Chemistry, Faculty of Biochemistry, Weizmann Institute of Science, Rehovot, Israel

Guest Editors
  • Joanna Chan

    Wuhan, China, Andorra

  • Tuhin Subhra Santra

    California Nano Systems Institute, University of California at Los Angeles, Los Angeles, United States

  • 2325dasdasd 2325dasdasd

    12312312, Australia

  • Joanna Chan

    Wuhan, China, Andorra

  • Jiangsong Jiang

    National Institute of Allergy and Infectious Diseases, Frederick National Laboratory for Cancer Research, National Institute of Health, United States

  • Palanisamy Arulselvan

    Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience (IBS), University Putra Malaysia, Serdang, Malaysia

  • Jiangsong Jiang

    National Institute of Allergy and Infectious Diseases, Frederick National Laboratory for Cancer Research, National Institute of Health, United States

  • Karthik Bodhinathan

    Sanford-Burnham Medical Research Institute, La Jolla, United States

  • Manoj Kumar Upadhyay

    Department of Education and Biotechnology, Biotech Park, Lucknow, India

  • M.Prasad Naidu

    Department of Biochemistry, Advance Research centre, Narayana Medical College and Hospital, Nellore, India

  • AMIT SHARMA

    Department of Physics, College of Engineering, Teerthanker Mahaveer University, Moradabad, India

  • Saurabh Maru

    Department of Pharmacy, Shri G S Institute of Technology and Science, Indore, India

  • Atul Bhangale

    Biologics Research amd Process Development, Bristol Myers Squibb, United States

  • Andrea Greschner

    Institut national de la recherche scientifique - Energie, materiaux, et telecommunications, Varennes, Canada

  • AMIT SHARMA

    Department of Physics, College of Engineering, Teerthanker Mahaveer University, Moradabad, India

  • Emad Dwidar

    Botany Department, Fayoum University, Fayoum, Egypt

  • Niha Ansari

    Gujarat University, Ahmedabad, India

  • A.K.M. Fahmidul Haque

    Respiratory and Antibiotics Laboratory, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh

  • Zhe Wang

    National Institutes of Health, United States

  • Cunye Qu

    Center for Craniofacial Molecular Biology, University of Southern California, Losangeles, United States

  • Vishvanath Tiwari

    Department of Biochemistry, Central University of Rajasthan, Ajmer, India

  • Vishvanath Tiwari

    Department of Biochemistry, Central University of Rajasthan, Ajmer, India

  • Ozlem Alptekin

    Department of Biochemistry, Cukurova University, Adana, Turkey

  • Niha Ansari

    Gujarat University, Ahmedabad, India

Published Articles
  • Physico-Chemical Analysis of Waste Water Used for Agricultural Purpose in Surrounding of Hyderabad, Sindh, Pakistan

    Ghulam Murtaza Mastoi , Khalid Hussain Lashari , Zameer Ali Palh , T. Jabeen Ursani , Anila Naz Soomro , Zulfiqar Ali Laghari , Abdul Waheed Mastoi

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 39-42
    Received: 4 August 2014
    Accepted: 8 August 2014
    Published: 2 September 2014
    DOI: 10.11648/j.ajbio.s.2014020601.17
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    Abstract: Irrigation with sewage is common practice of the farmers living in surrounding areas of urban colonies in Pakistan. Sewage contains a complex mixture of impurities. Waste water used for agricultural purpose without any treatment though it contains lot of the harmful impurities. During this study three villages were selected around the Hyderabad cit... Show More
  • Expression of Hox Genes, Zen (GB 51301) ANT and UBX during the Development of Honey Bee (Apis mellifera)

    Mariapia Viola-Magni , Samuela Cataldi

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 43-48
    Received: 7 August 2014
    Accepted: 14 August 2014
    Published: 2 September 2014
    DOI: 10.11648/j.ajbio.s.2014020601.18
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    Abstract: Homeobox genes are present in the genome of the honeybee Apis mellifera and their expression has been studied principally during embryonic development. The aim of this research was to evaluate expression of three key Hox genes from the larval period to the adult. The expression of honeybee GB51301, Ant and Ubx were examined in 24 and 72 hrs of larv... Show More
  • Patent Foramen Ovale is Associated with an Increased NAFLD Risk for Health of Young Men

    Erkan Kibrisli , Sinan Işcen , Salim Ozenc , Adem Parlak

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 35-38
    Received: 13 August 2014
    Accepted: 19 August 2014
    Published: 24 August 2014
    DOI: 10.11648/j.ajbio.s.2014020601.16
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    Abstract: Between March 2012 and July 2013, 1000 asymptomatic young military male underwent hepatic ultrasonography and echocardiography at Medical Check-up Center for general young health screening. Blood biochemistry, arterial blood pressure and anthropometric measurements were studied. All analyses were performed using the statistical package SPSS 15.0, w... Show More
  • Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine

    Ali Mohammed Yimer

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 22-34
    Received: 30 June 2014
    Accepted: 14 July 2014
    Published: 20 August 2014
    DOI: 10.11648/j.ajbio.s.2014020601.15
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    Abstract: The Schiff’s base ligands and their complexes with Ni(II), Cu(II) and Zn(II) were synthesized and characterized by elemental analysis molar conductivity, infrared and ultraviolet-visible spectroscopy and magnetic susceptibility measurements. The ligands, ethylenedianil of o-hydroxyphenylglyoxal, C18H16N2O4, have been synthesized by condensation of ... Show More
  • Morphological and Genetic Variation of Thrips parvispinus (Thysanoptera: Thripidae) in Chili Plantation (Capsicum annuum L.) in the Lowland and Highland of Jambi Province, Indonesia

    Asni Johari , Siti Herlinda , Yulia Pujiastuti , Chandra Irsan , Dewi Sartiami

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 17-21
    Received: 30 May 2014
    Accepted: 18 July 2014
    Published: 8 August 2014
    DOI: 10.11648/j.ajbio.s.2014020601.14
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    Abstract: Thrips parvispinus Karny (Thysanoptera: Thripidae) are dangerous pests for chili (Capsicum annuum L.). Thrips can be found in lowland to highland. The damage caused by thrips can reach 60% and this damage will be greater if the thrips also be vectors of plant virus diseases. The research aims to analyze morphological and genetic variation of T. par... Show More
  • Study of Enzymatic Hydrolysis of Bacterial Nanocellulose

    Michael Ioelovich

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 13-16
    Received: 28 June 2014
    Accepted: 10 July 2014
    Published: 13 July 2014
    DOI: 10.11648/j.ajbio.s.2014020601.13
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    Abstract: Bacterial nanocellulose is a subject of extensive research due to its promising potential applications in medicine, veterinary and cosmetics. In this paper, effect of structural characteristics on enzymatic hydrolysis of bacterial nanocellulose (BNC) and microcrystalline cellulose (MCC) has been studied. Despite the similar degree of crystallinity ... Show More
  • Structure and Physicochemical Properties of Nitrogenated Derivatives of Cellulose

    Michael Ioelovich

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 6-12
    Received: 28 June 2014
    Accepted: 10 July 2014
    Published: 13 July 2014
    DOI: 10.11648/j.ajbio.s.2014020601.12
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    Abstract: Nitrogenated derivatives of cellulose, and namely chitin and chitosan, are of commercial interest because of their antibacterial activity, biocompatibility, biodegradability and sorption ability. Structure and some physicochemical properties of these derivatives have been studied by methods of wide-angle X-ray scattering (WAXS), microcalorimetry an... Show More
  • The Study of Comparative Analgesic Activity of Lidocaine and Ropivacaine on Albino Rats

    Thota. Madhu Chaithanya , MundllaMudi. Prasad Naidu

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 1-5
    Received: 5 June 2014
    Accepted: 4 July 2014
    Published: 13 July 2014
    DOI: 10.11648/j.ajbio.s.2014020601.11
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    Abstract: Analgesics are the drugs which possess significant pain relieving properties by acting on the CNS or peripheral pain receptors without significantly affecting consciousness. Lidocaine and Ropivacaine are well studied individually; but there are conflicting reports of the comparison of actions between these two drugs both in experimental and clinica... Show More