Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes

Sherif Yousif Eid; Omar Abdel Hamid Ahmed-Farid; Hussein Mostafa El-Zaher; Mahmoud Mohammed Shabaan

doi:doi:10.11648/j.aap.20210601.14

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Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes

Sherif Yousif Eid, Omar Abdel Hamid Ahmed-Farid, Hussein Mostafa El-Zaher, Mahmoud Mohammed Shabaan

Published in Advances in Applied Physiology (Volume 6, Issue 1)

Received: 7 May 2021 Accepted: 25 May 2021 Published: 31 May 2021

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Abstract

The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2^nd, 3^rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P<0.05) superoxide dismutase (SOD), reduced glutathione (GSH) and glutathione disulfide (GSSG) during mid-, late-pregnancy and DD compared to control, celery and thyme increase malondialdehyde (MDA) (p<0.05) during mid-and late-pregnancy, respectively compared to other groups. Nitric oxide (NO) levels increased in thyme X celery (TxC) group during mid-pregnancy and DD with insignificantly compared with other groups. During mid-pregnancy TxC treatment increased (p<0.05) serotonin (5-HT) levels compared with other groups, the same was dopamine (DA), norepinephrine (NE) and tryptophan (Trp) levels (P>0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.

Published in	Advances in Applied Physiology (Volume 6, Issue 1)
DOI	10.11648/j.aap.20210601.14
Page(s)	23-29
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Thyme, Celery, Salinomycin, Immune System, Neurotransmitters, Milk Yield, Ewes

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APA Style

Sherif Yousif Eid, Omar Abdel Hamid Ahmed-Farid, Hussein Mostafa El-Zaher, Mahmoud Mohammed Shabaan. (2021). Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Advances in Applied Physiology, 6(1), 23-29. https://doi.org/10.11648/j.aap.20210601.14

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ACS Style

Sherif Yousif Eid; Omar Abdel Hamid Ahmed-Farid; Hussein Mostafa El-Zaher; Mahmoud Mohammed Shabaan. Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Adv. Appl. Physiol. 2021, 6(1), 23-29. doi: 10.11648/j.aap.20210601.14

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AMA Style

Sherif Yousif Eid, Omar Abdel Hamid Ahmed-Farid, Hussein Mostafa El-Zaher, Mahmoud Mohammed Shabaan. Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Adv Appl Physiol. 2021;6(1):23-29. doi: 10.11648/j.aap.20210601.14

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@article{10.11648/j.aap.20210601.14,
  author = {Sherif Yousif Eid and Omar Abdel Hamid Ahmed-Farid and Hussein Mostafa El-Zaher and Mahmoud Mohammed Shabaan},
  title = {Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes},
  journal = {Advances in Applied Physiology},
  volume = {6},
  number = {1},
  pages = {23-29},
  doi = {10.11648/j.aap.20210601.14},
  url = {https://doi.org/10.11648/j.aap.20210601.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.aap.20210601.14},
  abstract = {The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.},
 year = {2021}
}

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TY  - JOUR
T1  - Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes
AU  - Sherif Yousif Eid
AU  - Omar Abdel Hamid Ahmed-Farid
AU  - Hussein Mostafa El-Zaher
AU  - Mahmoud Mohammed Shabaan
Y1  - 2021/05/31
PY  - 2021
N1  - https://doi.org/10.11648/j.aap.20210601.14
DO  - 10.11648/j.aap.20210601.14
T2  - Advances in Applied Physiology
JF  - Advances in Applied Physiology
JO  - Advances in Applied Physiology
SP  - 23
EP  - 29
PB  - Science Publishing Group
SN  - 2471-9714
UR  - https://doi.org/10.11648/j.aap.20210601.14
AB  - The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.
VL  - 6
IS  - 1
ER  -

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Author Information

Sherif Yousif Eid

Biological Applications Department, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt
Omar Abdel Hamid Ahmed-Farid

Physiology Department, National Organization for Drug Control and Research (NODCAR), Cairo, Egypt
Hussein Mostafa El-Zaher

Biological Applications Department, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt
Mahmoud Mohammed Shabaan

Biological Applications Department, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt

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Sherif Yousif Eid, Omar Abdel Hamid Ahmed-Farid, Hussein Mostafa El-Zaher, Mahmoud Mohammed Shabaan. (2021). Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Advances in Applied Physiology, 6(1), 23-29. https://doi.org/10.11648/j.aap.20210601.14

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ACS Style

Sherif Yousif Eid; Omar Abdel Hamid Ahmed-Farid; Hussein Mostafa El-Zaher; Mahmoud Mohammed Shabaan. Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Adv. Appl. Physiol. 2021, 6(1), 23-29. doi: 10.11648/j.aap.20210601.14

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AMA Style

Sherif Yousif Eid, Omar Abdel Hamid Ahmed-Farid, Hussein Mostafa El-Zaher, Mahmoud Mohammed Shabaan. Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Adv Appl Physiol. 2021;6(1):23-29. doi: 10.11648/j.aap.20210601.14

Copy | Download

@article{10.11648/j.aap.20210601.14,
  author = {Sherif Yousif Eid and Omar Abdel Hamid Ahmed-Farid and Hussein Mostafa El-Zaher and Mahmoud Mohammed Shabaan},
  title = {Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes},
  journal = {Advances in Applied Physiology},
  volume = {6},
  number = {1},
  pages = {23-29},
  doi = {10.11648/j.aap.20210601.14},
  url = {https://doi.org/10.11648/j.aap.20210601.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.aap.20210601.14},
  abstract = {The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes
AU  - Sherif Yousif Eid
AU  - Omar Abdel Hamid Ahmed-Farid
AU  - Hussein Mostafa El-Zaher
AU  - Mahmoud Mohammed Shabaan
Y1  - 2021/05/31
PY  - 2021
N1  - https://doi.org/10.11648/j.aap.20210601.14
DO  - 10.11648/j.aap.20210601.14
T2  - Advances in Applied Physiology
JF  - Advances in Applied Physiology
JO  - Advances in Applied Physiology
SP  - 23
EP  - 29
PB  - Science Publishing Group
SN  - 2471-9714
UR  - https://doi.org/10.11648/j.aap.20210601.14
AB  - The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.
VL  - 6
IS  - 1
ER  -

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