Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City

Mufeed Jalil Ewadh; Nibras Yahya Al-Khafaji

doi:doi:10.11648/j.ab.20140204.11

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Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City

Mufeed Jalil Ewadh, Nibras Yahya Al-Khafaji

Published in Advances in Biochemistry (Volume 2, Issue 4)

Received: 18 July 2014 Accepted: 28 July 2014 Published: 10 August 2014

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Abstract

The study was conducted on fifty seven of type 2 diabetic patients and thirty one apparently healthy control subject. Blood samples obtained from all subjects from Marjan Medical City and AL-Hilla Teaching Hospital in Babylon Province. The aim of this study to evaluate the differences of oxidant (nitric oxide and malonyldialdehyde), antioxidant enzyme (superoxide dismutase), trace elements (copper and zinc) and lipid profile in sera of type 2 diabetic patients and the control group. The results of present study reveal a significant increase in nitric oxide, malonyldialdehyde, copper, glucose, total cholesterol, TG, VLDL-cholesterol and LDL-cholesterol concentration in sera of type 2 diabetic patients when compared to those of the control group. Also this study show significant decrease in superoxide dismutase and zinc concentration in sera of type 2 diabetic patients when compared to those of the control group. The study concluded that type 2 diabetic patients is associated with increase oxidative stress. The increase of nitric oxide, malonyldialdehyde and copper concentration and decrease of super oxide dismutase and zinc concentration may contribute in the development of complications in diabetic patients.

Published in	Advances in Biochemistry (Volume 2, Issue 4)
DOI	10.11648/j.ab.20140204.11
Page(s)	50-54
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Diabetes Mullets, Nitric Oxide, Malonyldialdehyde, Superoxide Dismutase, Trace Elements

References

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APA Style

Mufeed Jalil Ewadh, Nibras Yahya Al-Khafaji. (2014). Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City. Advances in Biochemistry, 2(4), 50-54. https://doi.org/10.11648/j.ab.20140204.11

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ACS Style

Mufeed Jalil Ewadh; Nibras Yahya Al-Khafaji. Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City. Adv. Biochem. 2014, 2(4), 50-54. doi: 10.11648/j.ab.20140204.11

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AMA Style

Mufeed Jalil Ewadh, Nibras Yahya Al-Khafaji. Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City. Adv Biochem. 2014;2(4):50-54. doi: 10.11648/j.ab.20140204.11

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@article{10.11648/j.ab.20140204.11,
  author = {Mufeed Jalil Ewadh and Nibras Yahya Al-Khafaji},
  title = {Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City},
  journal = {Advances in Biochemistry},
  volume = {2},
  number = {4},
  pages = {50-54},
  doi = {10.11648/j.ab.20140204.11},
  url = {https://doi.org/10.11648/j.ab.20140204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20140204.11},
  abstract = {The study was conducted on fifty seven of type 2 diabetic patients and thirty one apparently healthy control subject. Blood samples obtained from all subjects from Marjan Medical City and AL-Hilla Teaching Hospital in Babylon Province. The aim of this study to evaluate the differences of oxidant (nitric oxide and malonyldialdehyde), antioxidant enzyme (superoxide dismutase), trace elements (copper and zinc) and lipid profile in sera of type 2 diabetic patients and the control group. The results of present study reveal a significant increase in nitric oxide, malonyldialdehyde, copper, glucose, total cholesterol, TG, VLDL-cholesterol and LDL-cholesterol concentration in sera of type 2 diabetic patients when compared to those of the control group. Also this study show significant decrease in superoxide dismutase and zinc concentration in sera of type 2 diabetic patients when compared to those of the control group. The study concluded that type 2 diabetic patients is associated with increase oxidative stress. The increase of nitric oxide, malonyldialdehyde and copper concentration and decrease of super oxide dismutase and zinc concentration may contribute in the development of complications in diabetic patients.},
 year = {2014}
}

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TY  - JOUR
T1  - Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City
AU  - Mufeed Jalil Ewadh
AU  - Nibras Yahya Al-Khafaji
Y1  - 2014/08/10
PY  - 2014
N1  - https://doi.org/10.11648/j.ab.20140204.11
DO  - 10.11648/j.ab.20140204.11
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 50
EP  - 54
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20140204.11
AB  - The study was conducted on fifty seven of type 2 diabetic patients and thirty one apparently healthy control subject. Blood samples obtained from all subjects from Marjan Medical City and AL-Hilla Teaching Hospital in Babylon Province. The aim of this study to evaluate the differences of oxidant (nitric oxide and malonyldialdehyde), antioxidant enzyme (superoxide dismutase), trace elements (copper and zinc) and lipid profile in sera of type 2 diabetic patients and the control group. The results of present study reveal a significant increase in nitric oxide, malonyldialdehyde, copper, glucose, total cholesterol, TG, VLDL-cholesterol and LDL-cholesterol concentration in sera of type 2 diabetic patients when compared to those of the control group. Also this study show significant decrease in superoxide dismutase and zinc concentration in sera of type 2 diabetic patients when compared to those of the control group. The study concluded that type 2 diabetic patients is associated with increase oxidative stress. The increase of nitric oxide, malonyldialdehyde and copper concentration and decrease of super oxide dismutase and zinc concentration may contribute in the development of complications in diabetic patients.
VL  - 2
IS  - 4
ER  -

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Author Information

Mufeed Jalil Ewadh

Babylon University, College of Medicine, Department of Biochemistry, Hilla, Iraq
Nibras Yahya Al-Khafaji

Babylon University, College of Medicine, Department of Biochemistry, Hilla, Iraq

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Plain Text BibTeX RIS

APA Style

Mufeed Jalil Ewadh, Nibras Yahya Al-Khafaji. (2014). Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City. Advances in Biochemistry, 2(4), 50-54. https://doi.org/10.11648/j.ab.20140204.11

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ACS Style

Mufeed Jalil Ewadh; Nibras Yahya Al-Khafaji. Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City. Adv. Biochem. 2014, 2(4), 50-54. doi: 10.11648/j.ab.20140204.11

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AMA Style

Mufeed Jalil Ewadh, Nibras Yahya Al-Khafaji. Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City. Adv Biochem. 2014;2(4):50-54. doi: 10.11648/j.ab.20140204.11

Copy | Download

@article{10.11648/j.ab.20140204.11,
  author = {Mufeed Jalil Ewadh and Nibras Yahya Al-Khafaji},
  title = {Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City},
  journal = {Advances in Biochemistry},
  volume = {2},
  number = {4},
  pages = {50-54},
  doi = {10.11648/j.ab.20140204.11},
  url = {https://doi.org/10.11648/j.ab.20140204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20140204.11},
  abstract = {The study was conducted on fifty seven of type 2 diabetic patients and thirty one apparently healthy control subject. Blood samples obtained from all subjects from Marjan Medical City and AL-Hilla Teaching Hospital in Babylon Province. The aim of this study to evaluate the differences of oxidant (nitric oxide and malonyldialdehyde), antioxidant enzyme (superoxide dismutase), trace elements (copper and zinc) and lipid profile in sera of type 2 diabetic patients and the control group. The results of present study reveal a significant increase in nitric oxide, malonyldialdehyde, copper, glucose, total cholesterol, TG, VLDL-cholesterol and LDL-cholesterol concentration in sera of type 2 diabetic patients when compared to those of the control group. Also this study show significant decrease in superoxide dismutase and zinc concentration in sera of type 2 diabetic patients when compared to those of the control group. The study concluded that type 2 diabetic patients is associated with increase oxidative stress. The increase of nitric oxide, malonyldialdehyde and copper concentration and decrease of super oxide dismutase and zinc concentration may contribute in the development of complications in diabetic patients.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - Evaluation of Nitric Oxide and Some Biochemical Changes in Type 2 Diabetic Patients in Hilla City
AU  - Mufeed Jalil Ewadh
AU  - Nibras Yahya Al-Khafaji
Y1  - 2014/08/10
PY  - 2014
N1  - https://doi.org/10.11648/j.ab.20140204.11
DO  - 10.11648/j.ab.20140204.11
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 50
EP  - 54
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20140204.11
AB  - The study was conducted on fifty seven of type 2 diabetic patients and thirty one apparently healthy control subject. Blood samples obtained from all subjects from Marjan Medical City and AL-Hilla Teaching Hospital in Babylon Province. The aim of this study to evaluate the differences of oxidant (nitric oxide and malonyldialdehyde), antioxidant enzyme (superoxide dismutase), trace elements (copper and zinc) and lipid profile in sera of type 2 diabetic patients and the control group. The results of present study reveal a significant increase in nitric oxide, malonyldialdehyde, copper, glucose, total cholesterol, TG, VLDL-cholesterol and LDL-cholesterol concentration in sera of type 2 diabetic patients when compared to those of the control group. Also this study show significant decrease in superoxide dismutase and zinc concentration in sera of type 2 diabetic patients when compared to those of the control group. The study concluded that type 2 diabetic patients is associated with increase oxidative stress. The increase of nitric oxide, malonyldialdehyde and copper concentration and decrease of super oxide dismutase and zinc concentration may contribute in the development of complications in diabetic patients.
VL  - 2
IS  - 4
ER  -

Copy | Download