The effect of garlic powder at 5% and 10% level on plasma lipid profile was investigated in hypercholesterolemic rats. Male albino rats were fed a diet containing 20% fat and 1% cholesterol for two weeks to provoke hypercholesterolemia. The hypercholesterolemic rats were divided into three groups B, C and D. Group A rats were fed with normal diet, Group B were maintained on the hyper diet, Group C were fed hyper diet +5% garlic powder, Group D were fed hyper diet with +10% garlic powder. They were maintained on this diet for four weeks. Results showed that the plasma total cholesterol and LDL-C was significantly reduced in the treated groups (C and D) compared to the hypercholesterolemic control (Group B), while the HDL-C was significantly increased (P<0.05). Also plasma enzyme activities of Aspartate and Alanine Aminotransferases (AST. ALT) and Alkaline Phosphatase (ALP) showed a slight decrease in the treated rats. It is concluded that consumption of dry garlic powder at the level used in this study could be beneficial on the plasma lipid profile in hypercholesterolemia.
| Published in | Advances in Biochemistry (Volume 2, Issue 3) |
| DOI | 10.11648/j.ab.20140203.12 |
| Page(s) | 45-49 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Hypercholesterolemia, Aminotransferases, Lipid Profile
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APA Style
Ajayi O. B., Ajayi D. D. (2014). Effect of Dry Garlic Powder on Plasma Lipid Profile and Enzyme Activities in Some Tissues of Hypercholesterolemic Rats. Advances in Biochemistry, 2(3), 45-49. https://doi.org/10.11648/j.ab.20140203.12
ACS Style
Ajayi O. B.; Ajayi D. D. Effect of Dry Garlic Powder on Plasma Lipid Profile and Enzyme Activities in Some Tissues of Hypercholesterolemic Rats. Adv. Biochem. 2014, 2(3), 45-49. doi: 10.11648/j.ab.20140203.12
AMA Style
Ajayi O. B., Ajayi D. D. Effect of Dry Garlic Powder on Plasma Lipid Profile and Enzyme Activities in Some Tissues of Hypercholesterolemic Rats. Adv Biochem. 2014;2(3):45-49. doi: 10.11648/j.ab.20140203.12
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Download@article{10.11648/j.ab.20140203.12,
author = {Ajayi O. B. and Ajayi D. D.},
title = {Effect of Dry Garlic Powder on Plasma Lipid Profile and Enzyme Activities in Some Tissues of Hypercholesterolemic Rats},
journal = {Advances in Biochemistry},
volume = {2},
number = {3},
pages = {45-49},
doi = {10.11648/j.ab.20140203.12},
url = {https://doi.org/10.11648/j.ab.20140203.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20140203.12},
abstract = {The effect of garlic powder at 5% and 10% level on plasma lipid profile was investigated in hypercholesterolemic rats. Male albino rats were fed a diet containing 20% fat and 1% cholesterol for two weeks to provoke hypercholesterolemia. The hypercholesterolemic rats were divided into three groups B, C and D. Group A rats were fed with normal diet, Group B were maintained on the hyper diet, Group C were fed hyper diet +5% garlic powder, Group D were fed hyper diet with +10% garlic powder. They were maintained on this diet for four weeks. Results showed that the plasma total cholesterol and LDL-C was significantly reduced in the treated groups (C and D) compared to the hypercholesterolemic control (Group B), while the HDL-C was significantly increased (P<0.05). Also plasma enzyme activities of Aspartate and Alanine Aminotransferases (AST. ALT) and Alkaline Phosphatase (ALP) showed a slight decrease in the treated rats. It is concluded that consumption of dry garlic powder at the level used in this study could be beneficial on the plasma lipid profile in hypercholesterolemia.},
year = {2014}
}
TY - JOUR T1 - Effect of Dry Garlic Powder on Plasma Lipid Profile and Enzyme Activities in Some Tissues of Hypercholesterolemic Rats AU - Ajayi O. B. AU - Ajayi D. D. Y1 - 2014/07/20 PY - 2014 N1 - https://doi.org/10.11648/j.ab.20140203.12 DO - 10.11648/j.ab.20140203.12 T2 - Advances in Biochemistry JF - Advances in Biochemistry JO - Advances in Biochemistry SP - 45 EP - 49 PB - Science Publishing Group SN - 2329-0862 UR - https://doi.org/10.11648/j.ab.20140203.12 AB - The effect of garlic powder at 5% and 10% level on plasma lipid profile was investigated in hypercholesterolemic rats. Male albino rats were fed a diet containing 20% fat and 1% cholesterol for two weeks to provoke hypercholesterolemia. The hypercholesterolemic rats were divided into three groups B, C and D. Group A rats were fed with normal diet, Group B were maintained on the hyper diet, Group C were fed hyper diet +5% garlic powder, Group D were fed hyper diet with +10% garlic powder. They were maintained on this diet for four weeks. Results showed that the plasma total cholesterol and LDL-C was significantly reduced in the treated groups (C and D) compared to the hypercholesterolemic control (Group B), while the HDL-C was significantly increased (P<0.05). Also plasma enzyme activities of Aspartate and Alanine Aminotransferases (AST. ALT) and Alkaline Phosphatase (ALP) showed a slight decrease in the treated rats. It is concluded that consumption of dry garlic powder at the level used in this study could be beneficial on the plasma lipid profile in hypercholesterolemia. VL - 2 IS - 3 ER -
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