The effect of naphthalene on selected haematological and histopathological parameters as wellrelative growth rate in the tropical African catfish was evaluated. Healthy juvenile fish (n = 90) weighing 19.7±1.8 g were exposed to sublethal concentrations of naphthalene over a period of 35 days after which haematological and histopathological parameters were analyzed. The medianlethal concentration LC 50 of naphthalene was determined to be 6600 μg/L in Catfish withestimated safe level ranging from 0.066 to 330 μg/L. Sublethal concentrations of naphthalene ledto significant declines in red blood cell (RBC) counts, haemoglobin concentration andhaematocrit. The erythrocyte indices showed mixed results with mean corpuscular haemoglobinconcentration (MCHC) showing significant elevation while changes in mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) were not significant. Naphthalene wasimmunotoxic in exposed fish leading to significant elevations in circulating white blood cells (WBC). There was also a significant increase in platelet (PLT) count in naphthalene exposedfish. Growth rate significantly reduced in a dose response pattern. While there was no observedhistopathological alteration in the liver of exposed fish, haemorrhage with blood coagulation wasobserved in the gill sections. There were changes in the haematological parameters. Thesignificant reduction in (RBC) and the reduced growth rate of catfish shows that naphthalene isof environmental concern due to its toxicity.
| Published in | Advances in Biochemistry (Volume 10, Issue 2) |
| DOI | 10.11648/j.ab.20221002.11 |
| Page(s) | 41-46 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Histopathological, Hematological, Cat fish, Naphthalene, Sublethal
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APA Style
Odom Theophilus Chikodi, Ekop Mercy Otobong, Chigbu Timothy Onyekachi, Osuagwu Uchechukwu Obinna. (2022). Histopathological and Hematological Alterations in Cat fish Exposed to Sublethal Concentrations of Naphthalene, a Polycyclic Aromatic Hydrocarbon. Advances in Biochemistry, 10(2), 41-46. https://doi.org/10.11648/j.ab.20221002.11
ACS Style
Odom Theophilus Chikodi; Ekop Mercy Otobong; Chigbu Timothy Onyekachi; Osuagwu Uchechukwu Obinna. Histopathological and Hematological Alterations in Cat fish Exposed to Sublethal Concentrations of Naphthalene, a Polycyclic Aromatic Hydrocarbon. Adv. Biochem. 2022, 10(2), 41-46. doi: 10.11648/j.ab.20221002.11
AMA Style
Odom Theophilus Chikodi, Ekop Mercy Otobong, Chigbu Timothy Onyekachi, Osuagwu Uchechukwu Obinna. Histopathological and Hematological Alterations in Cat fish Exposed to Sublethal Concentrations of Naphthalene, a Polycyclic Aromatic Hydrocarbon. Adv Biochem. 2022;10(2):41-46. doi: 10.11648/j.ab.20221002.11
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author = {Odom Theophilus Chikodi and Ekop Mercy Otobong and Chigbu Timothy Onyekachi and Osuagwu Uchechukwu Obinna},
title = {Histopathological and Hematological Alterations in Cat fish Exposed to Sublethal Concentrations of Naphthalene, a Polycyclic Aromatic Hydrocarbon},
journal = {Advances in Biochemistry},
volume = {10},
number = {2},
pages = {41-46},
doi = {10.11648/j.ab.20221002.11},
url = {https://doi.org/10.11648/j.ab.20221002.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20221002.11},
abstract = {The effect of naphthalene on selected haematological and histopathological parameters as wellrelative growth rate in the tropical African catfish was evaluated. Healthy juvenile fish (n = 90) weighing 19.7±1.8 g were exposed to sublethal concentrations of naphthalene over a period of 35 days after which haematological and histopathological parameters were analyzed. The medianlethal concentration LC 50 of naphthalene was determined to be 6600 μg/L in Catfish withestimated safe level ranging from 0.066 to 330 μg/L. Sublethal concentrations of naphthalene ledto significant declines in red blood cell (RBC) counts, haemoglobin concentration andhaematocrit. The erythrocyte indices showed mixed results with mean corpuscular haemoglobinconcentration (MCHC) showing significant elevation while changes in mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) were not significant. Naphthalene wasimmunotoxic in exposed fish leading to significant elevations in circulating white blood cells (WBC). There was also a significant increase in platelet (PLT) count in naphthalene exposedfish. Growth rate significantly reduced in a dose response pattern. While there was no observedhistopathological alteration in the liver of exposed fish, haemorrhage with blood coagulation wasobserved in the gill sections. There were changes in the haematological parameters. Thesignificant reduction in (RBC) and the reduced growth rate of catfish shows that naphthalene isof environmental concern due to its toxicity.},
year = {2022}
}
TY - JOUR T1 - Histopathological and Hematological Alterations in Cat fish Exposed to Sublethal Concentrations of Naphthalene, a Polycyclic Aromatic Hydrocarbon AU - Odom Theophilus Chikodi AU - Ekop Mercy Otobong AU - Chigbu Timothy Onyekachi AU - Osuagwu Uchechukwu Obinna Y1 - 2022/04/09 PY - 2022 N1 - https://doi.org/10.11648/j.ab.20221002.11 DO - 10.11648/j.ab.20221002.11 T2 - Advances in Biochemistry JF - Advances in Biochemistry JO - Advances in Biochemistry SP - 41 EP - 46 PB - Science Publishing Group SN - 2329-0862 UR - https://doi.org/10.11648/j.ab.20221002.11 AB - The effect of naphthalene on selected haematological and histopathological parameters as wellrelative growth rate in the tropical African catfish was evaluated. Healthy juvenile fish (n = 90) weighing 19.7±1.8 g were exposed to sublethal concentrations of naphthalene over a period of 35 days after which haematological and histopathological parameters were analyzed. The medianlethal concentration LC 50 of naphthalene was determined to be 6600 μg/L in Catfish withestimated safe level ranging from 0.066 to 330 μg/L. Sublethal concentrations of naphthalene ledto significant declines in red blood cell (RBC) counts, haemoglobin concentration andhaematocrit. The erythrocyte indices showed mixed results with mean corpuscular haemoglobinconcentration (MCHC) showing significant elevation while changes in mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) were not significant. Naphthalene wasimmunotoxic in exposed fish leading to significant elevations in circulating white blood cells (WBC). There was also a significant increase in platelet (PLT) count in naphthalene exposedfish. Growth rate significantly reduced in a dose response pattern. While there was no observedhistopathological alteration in the liver of exposed fish, haemorrhage with blood coagulation wasobserved in the gill sections. There were changes in the haematological parameters. Thesignificant reduction in (RBC) and the reduced growth rate of catfish shows that naphthalene isof environmental concern due to its toxicity. VL - 10 IS - 2 ER -
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