Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine

Ibrahim Kani Aminu; Abdulwaris Abdullahi Daura

doi:doi:10.11648/j.ajac.20231103.13

| Peer-Reviewed

Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura

Published in American Journal of Applied Chemistry (Volume 11, Issue 3)

Received: 20 April 2023 Accepted: 9 May 2023 Published: 6 July 2023

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω^-1cm²mol^-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).

Published in	American Journal of Applied Chemistry (Volume 11, Issue 3)
DOI	10.11648/j.ajac.20231103.13
Page(s)	86-94
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Schiff Base, Complexes, 2-hydroxybenzaldehyde, 1-naphthylamine, Antimicrobial Activity

References

[1]	Aliyu, H. N and Zayyan, R. S (2013), Synthesis and characterization of biologically active N,N-Bis(4-bezene azo salicylidene-o-phenylenediiminato cobalt(II) complex. Bayero journal of pure and applied science 6 (2): 127-131.
[2]	Akmal, S. G., Mohsen, S. A., Atiat, S. B. and Said, M. T. (2007), Synthesis, characterization and biological activity of some platinum (II) complexes with Schiff bases derived from salicylaldehyde, 2-furaldehyde and phenylenediamine, Spectrochimica Acta Part A 67, 114-121.
[3]	Bhausaheb, K. M., Anil, S. K. and Trimbak K. C. (2013), Formation of N-Salicylidene-p-chloroaniline; a kinetic Study ActaChim pharm. Indica 4 (1): 40-46.
[4]	Chaudhary, N. K. (2013) Synthesis and medicinal use of Metal Complexes of Schiff bases, a multidisciplinary Journal of Science, Technology and Mathematics. 9 (1): 75-80.
[5]	Devesh, K. (2014). Review on biological important mixed ligand Complexes and their Application. Asian journal of Biochemical and Pharmaceutical Research issue. 1 (4): 22-135.
[6]	Gomathi, V. and Selvameena, R. (2014), Synthesis, spectral characterization and antimicrobial screening of novel Schiff bases from sulfa drugs, International Journal of Pharmacy and Pharmaceutical Sciences, 6 (1).
[7]	Ibrahim, A. K., Yusuf, B. A. and Hamisu, A. (2017), Synthesis, Characterization and Antimicrobial Studies of Cu(II) and Zn(II) Complexes with the Schiff base N-salicylidene-4-chloroaniline, ChemSearch Journal, 8 (2): 68-74.
[8]	Ignat, L. (2012), Complexes of some Transition Metal with Ketone and azomethinic derivatives of Ketones. PhD Thesis University of Bucharest Romania 2 (1): 256-285.
[9]	Jai, D., Suman, D. and Ashwani, K. (2016), Synthesis, antibacterial evaluation and QSAR analysis of Schiff base complexes derived from [2,2′-(ethylenedioxy)bis(ethylamine)] and aromatic aldehyde, Journal of Royal Society of Chemistry, (7): 932.
[10]	Javed, I. (2006), Biological properties of Chloro-salicylidene Amine and Complexes with Co(II) and Cu(II), Turk. Journal of Biochemistry, 30 (1): 1-4.
[11]	Kawkab, A. and Al-Ali, H. (2010), Synthesis, characterization and study of electrical properties of Fe(III) and Al(III) of Schiff base. Journal of inorganic chemistry 2 (3): 1-11.
[12]	Matangi, S., Pragathi, J., Ushaiah and Gyanakumari, C. (2012), Synthesis¸ structural characterization, molecular modeling and antimicrobial studies of transition metal complexes of Schiff base ligand derived from 5-chlorosalicylaldehyde and 2-(2-aminophenyl) 1H-benzimidazole, Journal of Chemical and Pharmaceutical Research, 2012, 4 (3): 1553-1561.
[13]	Moamens R and Ibrahim, M. (2013), Spectroscopic, Structural and Electrical Conductivity studies of Cu(II), Ni(II) and C(II) Complexes derived from 4-acetylpyridine with thiosemicarbazide. International journal of Electrochemical Science. 1 (8): 9898-9917.
[14]	Nagajothi, A., Kiruthika, A., Chitra, S. and Parameswari, K. (2013) Fe(III) Complexes with Schiff base ligand: Synthesis, Characterization, Antimicrobial Studies, Research Journal of Chemical Sciences, 3 (2), 35-43.
[15]	Naila, A. b., Rashid, S., Rashmi, S., Rahul, G., Shankardutt, P., Kabita, S., Chavan, R. P. and Satu, T. C. (2015), Synthesis and characterization of novel Schiff’s base Ni(II) and Fe(III) & its complexes with its anti-bacterial activity, International Journal of chemical societies, 3 (4): 39-41.
[16]	Neelofar, N. A., Adnan K., Salma, A., Noureen, A. K. and Muhammad, B. (2017), Synthesis of Schiff bases derived from 2-hydroxy-1-naphthaldehyde, and their Tin(II) complexes for antimicrobial and antioxidant activities, Bull. Chem. Soc. Ethiop. 2017, 31 (3), 445-456.
[17]	Sultan, Y., Selehattin, Y., Gulsen, S., Murat S., Mustafa, Y. and Kamran, P. (2013) Synthesis, spectroscopic studies and electrochemical properties of Schiff bases derived from 2-hydroxy aromatic aldehyde and phenazopypridine hydrochloride, J. Serb. Chem. Soc. 78 (6) 795-804.
[18]	Tariq, M. (2010), Synthesis and Characterization of the amino acid Schiff bases and their Complexes with Cu(II). PhD Research report, School of Chemistry University of Manchester, Uk. 1 (1): 1-24.

Cite This Article

Plain Text BibTeX RIS

APA Style

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. (2023). Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. American Journal of Applied Chemistry, 11(3), 86-94. https://doi.org/10.11648/j.ajac.20231103.13

Copy | Download

ACS Style

Ibrahim Kani Aminu; Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am. J. Appl. Chem. 2023, 11(3), 86-94. doi: 10.11648/j.ajac.20231103.13

Copy | Download

AMA Style

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am J Appl Chem. 2023;11(3):86-94. doi: 10.11648/j.ajac.20231103.13

Copy | Download

@article{10.11648/j.ajac.20231103.13,
  author = {Ibrahim Kani Aminu and Abdulwaris Abdullahi Daura},
  title = {Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine},
  journal = {American Journal of Applied Chemistry},
  volume = {11},
  number = {3},
  pages = {86-94},
  doi = {10.11648/j.ajac.20231103.13},
  url = {https://doi.org/10.11648/j.ajac.20231103.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231103.13},
  abstract = {The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine
AU  - Ibrahim Kani Aminu
AU  - Abdulwaris Abdullahi Daura
Y1  - 2023/07/06
PY  - 2023
N1  - https://doi.org/10.11648/j.ajac.20231103.13
DO  - 10.11648/j.ajac.20231103.13
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 86
EP  - 94
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20231103.13
AB  - The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).
VL  - 11
IS  - 3
ER  -

Copy | Download

Author Information

Ibrahim Kani Aminu

Department of Pure and Industrial Chemistry, Bayero University, Kano, Nigeria
Abdulwaris Abdullahi Daura

Mechanical Engineering Department, Usman Danfodiyo University, Sokoto, Nigeria

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. (2023). Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. American Journal of Applied Chemistry, 11(3), 86-94. https://doi.org/10.11648/j.ajac.20231103.13

Copy | Download

ACS Style

Ibrahim Kani Aminu; Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am. J. Appl. Chem. 2023, 11(3), 86-94. doi: 10.11648/j.ajac.20231103.13

Copy | Download

AMA Style

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am J Appl Chem. 2023;11(3):86-94. doi: 10.11648/j.ajac.20231103.13

Copy | Download

@article{10.11648/j.ajac.20231103.13,
  author = {Ibrahim Kani Aminu and Abdulwaris Abdullahi Daura},
  title = {Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine},
  journal = {American Journal of Applied Chemistry},
  volume = {11},
  number = {3},
  pages = {86-94},
  doi = {10.11648/j.ajac.20231103.13},
  url = {https://doi.org/10.11648/j.ajac.20231103.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231103.13},
  abstract = {The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine
AU  - Ibrahim Kani Aminu
AU  - Abdulwaris Abdullahi Daura
Y1  - 2023/07/06
PY  - 2023
N1  - https://doi.org/10.11648/j.ajac.20231103.13
DO  - 10.11648/j.ajac.20231103.13
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 86
EP  - 94
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20231103.13
AB  - The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).
VL  - 11
IS  - 3
ER  -

Copy | Download