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In-vitro Evaluation of Anti-oxidant and Anti-inflammatory Potential of Bio-synthesized Silver Nanoparticles from Endemic Medicinal Plant Species Terminalia pallida

Received: 17 December 2021     Accepted: 8 February 2022     Published: 9 April 2022
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Abstract

Background: The Seshachalam hill ranges of Eastern Ghats are known for their endemic flora. There were seven endemic species situated here in which present plant species Terminalia pallida (T. pallida) is one, this Endemic semi-tree species has a great medicinal value; at the same time, due to the presence of different types of secondary metabolites, they easily form nanoparticles and exhibit certain high-quality characteristics after being combined with noble metals like silver. Objective: These Silver Nanoparticles (SNPs) display peculiar characteristics in their nano level which shows more effectiveness compared to their raw extracts, with negligible side effects. The present work shows in vitro antioxidant (DPPH radical scavenging assay) and anti-inflammatory (inhibition of albumin denaturation) applications of SNPs synthesized from leaf, bark, and fruit extracts. Method: Antioxidant activity was carried out by Burits and Bucar method with slight changes and about anti-inflammatory (inhibition of albumin denaturation) assay was carried out by Dunnet method. Result: In these experiments, the results obtained were positive. The result, when compared among the three parts, showed more positive results in antioxidant assay SNPs synthesized from fruit, and dominated results in the anti-inflammatory test SNPs synthesized from the bark. Conclusion: By studying the applications of SNPs it is confirmed that the biosynthesized silver nanoparticles (SNPs) are helpful in the production of various medicines hence SNPs can be recommended ingredients for biomedicine.

Published in American Journal of Nanosciences (Volume 8, Issue 1)
DOI 10.11648/j.ajn.20220801.11
Page(s) 1-7
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Terminalia pallida, Endemic Medicinal Plant, Silver Nanoparticles, in-vitro Antioxidant, Anti-inflammatory Assays

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Cite This Article
  • APA Style

    P. Rama Mohan, N. Savithramma. (2022). In-vitro Evaluation of Anti-oxidant and Anti-inflammatory Potential of Bio-synthesized Silver Nanoparticles from Endemic Medicinal Plant Species Terminalia pallida. American Journal of Nanosciences, 8(1), 1-7. https://doi.org/10.11648/j.ajn.20220801.11

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    ACS Style

    P. Rama Mohan; N. Savithramma. In-vitro Evaluation of Anti-oxidant and Anti-inflammatory Potential of Bio-synthesized Silver Nanoparticles from Endemic Medicinal Plant Species Terminalia pallida. Am. J. Nanosci. 2022, 8(1), 1-7. doi: 10.11648/j.ajn.20220801.11

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    AMA Style

    P. Rama Mohan, N. Savithramma. In-vitro Evaluation of Anti-oxidant and Anti-inflammatory Potential of Bio-synthesized Silver Nanoparticles from Endemic Medicinal Plant Species Terminalia pallida. Am J Nanosci. 2022;8(1):1-7. doi: 10.11648/j.ajn.20220801.11

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  • @article{10.11648/j.ajn.20220801.11,
      author = {P. Rama Mohan and N. Savithramma},
      title = {In-vitro Evaluation of Anti-oxidant and Anti-inflammatory Potential of Bio-synthesized Silver Nanoparticles from Endemic Medicinal Plant Species Terminalia pallida},
      journal = {American Journal of Nanosciences},
      volume = {8},
      number = {1},
      pages = {1-7},
      doi = {10.11648/j.ajn.20220801.11},
      url = {https://doi.org/10.11648/j.ajn.20220801.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajn.20220801.11},
      abstract = {Background: The Seshachalam hill ranges of Eastern Ghats are known for their endemic flora. There were seven endemic species situated here in which present plant species Terminalia pallida (T. pallida) is one, this Endemic semi-tree species has a great medicinal value; at the same time, due to the presence of different types of secondary metabolites, they easily form nanoparticles and exhibit certain high-quality characteristics after being combined with noble metals like silver. Objective: These Silver Nanoparticles (SNPs) display peculiar characteristics in their nano level which shows more effectiveness compared to their raw extracts, with negligible side effects. The present work shows in vitro antioxidant (DPPH radical scavenging assay) and anti-inflammatory (inhibition of albumin denaturation) applications of SNPs synthesized from leaf, bark, and fruit extracts. Method: Antioxidant activity was carried out by Burits and Bucar method with slight changes and about anti-inflammatory (inhibition of albumin denaturation) assay was carried out by Dunnet method. Result: In these experiments, the results obtained were positive. The result, when compared among the three parts, showed more positive results in antioxidant assay SNPs synthesized from fruit, and dominated results in the anti-inflammatory test SNPs synthesized from the bark. Conclusion: By studying the applications of SNPs it is confirmed that the biosynthesized silver nanoparticles (SNPs) are helpful in the production of various medicines hence SNPs can be recommended ingredients for biomedicine.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - In-vitro Evaluation of Anti-oxidant and Anti-inflammatory Potential of Bio-synthesized Silver Nanoparticles from Endemic Medicinal Plant Species Terminalia pallida
    AU  - P. Rama Mohan
    AU  - N. Savithramma
    Y1  - 2022/04/09
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ajn.20220801.11
    DO  - 10.11648/j.ajn.20220801.11
    T2  - American Journal of Nanosciences
    JF  - American Journal of Nanosciences
    JO  - American Journal of Nanosciences
    SP  - 1
    EP  - 7
    PB  - Science Publishing Group
    SN  - 2575-4858
    UR  - https://doi.org/10.11648/j.ajn.20220801.11
    AB  - Background: The Seshachalam hill ranges of Eastern Ghats are known for their endemic flora. There were seven endemic species situated here in which present plant species Terminalia pallida (T. pallida) is one, this Endemic semi-tree species has a great medicinal value; at the same time, due to the presence of different types of secondary metabolites, they easily form nanoparticles and exhibit certain high-quality characteristics after being combined with noble metals like silver. Objective: These Silver Nanoparticles (SNPs) display peculiar characteristics in their nano level which shows more effectiveness compared to their raw extracts, with negligible side effects. The present work shows in vitro antioxidant (DPPH radical scavenging assay) and anti-inflammatory (inhibition of albumin denaturation) applications of SNPs synthesized from leaf, bark, and fruit extracts. Method: Antioxidant activity was carried out by Burits and Bucar method with slight changes and about anti-inflammatory (inhibition of albumin denaturation) assay was carried out by Dunnet method. Result: In these experiments, the results obtained were positive. The result, when compared among the three parts, showed more positive results in antioxidant assay SNPs synthesized from fruit, and dominated results in the anti-inflammatory test SNPs synthesized from the bark. Conclusion: By studying the applications of SNPs it is confirmed that the biosynthesized silver nanoparticles (SNPs) are helpful in the production of various medicines hence SNPs can be recommended ingredients for biomedicine.
    VL  - 8
    IS  - 1
    ER  - 

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Author Information
  • Department of Botany, Sri Venkateswara University, Tirupati, India

  • Department of Botany, Sri Venkateswara University, Tirupati, India

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