We report a case of a male newborn who was evaluated due to persistent jaundice. Evaluation showed hypothyroidism associated with infantile hemangioma of the liver. Euthyroidism and regression of the hepatic hemangiomas were obtained with L-thyroxin and Propranolol treatment. This case emphasizes the importance of screening for hypothyroidism in patients with neonatal hemangiomatosis.
| Published in | American Journal of Pediatrics (Volume 2, Issue 1) |
| DOI | 10.11648/j.ajp.20160201.11 |
| Page(s) | 1-3 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2016. Published by Science Publishing Group |
Hepatic Hemangioendotheliomas, Jaundice, Hypothyroidism
| [1] | Tan ST, Velickovic M, Ruger BM, Davis PF. Cellular and extracellular markers of hem-angioma. Plast Reconstr Surg. 2000; 106(3): 529–537. |
| [2] | Lister, WA. The natural history of the strawberry nevi. Lancet. 1938; 1: 1429. |
| [3] | Huang SA, Tu HM, Harney JW, Venihaki M, Butte AJ, Kozakewich HP, Fisman SJ, Larsen PR. Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med. 2000; 343: 185–189. |
| [4] | Ayling RM, Davenport M, Hadzic N, Metcalfe R, Buchanan CR, Howard ER, Mieli−Vergani G. Hepatic hemangioendothelioma associated with production of humoral thyrotropin−like factor. J Pediatr. 2001; 138: 932–935. |
| [5] | Dena M, Selby J, Thomas Stocker, Myron A, Waclawiw, Chales L, Hitchcock, Kamal G, Ishak. Infantile hemangioendothelioma of the liver. Hepatology 1994; 20: 39-45. |
| [6] | Fok TF, Chan MS, Metreweli C, Ng PC, Yeung CK, Li AK. Hepatic haemangioendothelioma presenting with early heart failure in a newborn: treatment with hepatic artery embolization and interferon. Acta Paediatr 1996; 85: 1373-5. |
| [7] | Lu CC, Ko SF, Liang CD, Kuo HW, Tiao MM. Infantile hepatic hemangioendothelioma presenting as early heart failure: report of two cases. Chang Gung Med J. 2002; 25: 405–410. |
| [8] | Riley MR, Garcia MG, Cox KL, Berquist WE, Kerner JA., Jr Hepatic infantile hemangioendothelioma with unusual manifestations. J Pediatr Gastroenterol Nutr. 2006; 42: 109–113. |
| [9] | Selby DM, Stocker JT, Waclawiw MA, Hitchcock CL, Ishak KG. Infantile hemangioendothelioma of the liver. Hepatology. 1994; 20 (1 Pt 1): 39–45. |
| [10] | Siegfried EC, Keenan WJ, Al-Jureidini S, Leaute-Labreze C, de la Roque ED, Taieb A. More on propranolol for hemangiomas of infancy. N Engl J Med. 2008; 359(26): 2846–2847. |
| [11] | Itinteang T, Withers A, Leadbitter P, Day D, Tan S. Pharmacologic therapies for infantile hemangioma: is there a rational basis? Plast Reconstr Surg. 2011; 128: 499–507. |
| [12] | Itinteang T, Withers AH, Davis PF, Tan ST. Biology of infantile hemangioma. Front Surg. 2014; 1: 38. |
| [13] | Tan ST, Itinteang T, Day DJ, O’Donnell C, Mathy JA, Leadbitter P.. Treatment of infantile haemangioma with captopril. Br J Dermatol. 2012; 167: 619–24. |
| [14] | Christou EM, Wargon O.. Effect of captopril on infantile haemangiomas: a retrospective case series. Aust J Dermatol. 2012; 53: 216–8. |
| [15] | Park SM, Chatterjee VK; Genetics of congenital hypothyroidism. J Med Genet. 2005; 42(5): 379-89. |
| [16] | Rastogi MV, LaFranchi SH; Congenital hypothyroidism. Orphanet J Rare Dis. 2010; 5: 17. |
APA Style
Ziad Albahri, Antonín Lukes. (2016). Difuse Infantile Hemangiomatosis with Consumptive Hypothyroidism in an Infant: A Case Report. American Journal of Pediatrics, 2(1), 1-3. https://doi.org/10.11648/j.ajp.20160201.11
ACS Style
Ziad Albahri; Antonín Lukes. Difuse Infantile Hemangiomatosis with Consumptive Hypothyroidism in an Infant: A Case Report. Am. J. Pediatr. 2016, 2(1), 1-3. doi: 10.11648/j.ajp.20160201.11
AMA Style
Ziad Albahri, Antonín Lukes. Difuse Infantile Hemangiomatosis with Consumptive Hypothyroidism in an Infant: A Case Report. Am J Pediatr. 2016;2(1):1-3. doi: 10.11648/j.ajp.20160201.11
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Download@article{10.11648/j.ajp.20160201.11,
author = {Ziad Albahri and Antonín Lukes},
title = {Difuse Infantile Hemangiomatosis with Consumptive Hypothyroidism in an Infant: A Case Report},
journal = {American Journal of Pediatrics},
volume = {2},
number = {1},
pages = {1-3},
doi = {10.11648/j.ajp.20160201.11},
url = {https://doi.org/10.11648/j.ajp.20160201.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20160201.11},
abstract = {We report a case of a male newborn who was evaluated due to persistent jaundice. Evaluation showed hypothyroidism associated with infantile hemangioma of the liver. Euthyroidism and regression of the hepatic hemangiomas were obtained with L-thyroxin and Propranolol treatment. This case emphasizes the importance of screening for hypothyroidism in patients with neonatal hemangiomatosis.},
year = {2016}
}
TY - JOUR T1 - Difuse Infantile Hemangiomatosis with Consumptive Hypothyroidism in an Infant: A Case Report AU - Ziad Albahri AU - Antonín Lukes Y1 - 2016/03/11 PY - 2016 N1 - https://doi.org/10.11648/j.ajp.20160201.11 DO - 10.11648/j.ajp.20160201.11 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 1 EP - 3 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20160201.11 AB - We report a case of a male newborn who was evaluated due to persistent jaundice. Evaluation showed hypothyroidism associated with infantile hemangioma of the liver. Euthyroidism and regression of the hepatic hemangiomas were obtained with L-thyroxin and Propranolol treatment. This case emphasizes the importance of screening for hypothyroidism in patients with neonatal hemangiomatosis. VL - 2 IS - 1 ER -
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