A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration

Nipun Shrestha; Dhruba Shrestha; Ashish Shrestha; Mala Shrestha

doi:doi:10.11648/j.ajp.20200603.38

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A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration

Nipun Shrestha, Dhruba Shrestha, Ashish Shrestha, Mala Shrestha

Published in American Journal of Pediatrics (Volume 6, Issue 3)

Received: 4 May 2020 Accepted: 22 July 2020 Published: 20 August 2020

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Abstract

Background: Febrile Seizure is defined as seizure occurring during febrile episode (body temperature > 100.4°F or 38°C) in a child between 6 to 60 months, in absence of CNS infection, metabolic abnormalities, neurological condition and a history of prior afebrile seizure. Some of the major concerns regarding febrile seizure are its duration and recurrence. Risk factors associated with its duration are poorly understood. Method: A retrospective study was conducted from January to December 2018 among children admitted to Siddhi Memorial Hospital (for Women and Children), Bhaktapur (Nepal) with a diagnosis of febrile seizure. Information on those children, including gender, age of onset, type of seizure, duration of seizure etc., were collected from patient records. Children meeting the standard definition of febrile seizure were included in the study. Data analysis was done using Microsoft Excel and STATA, version 15. A p value <0.05 was considered statistically significant. Result: A total of 1389 children had been admitted to pediatric department during the study period. Among them, 124 children (i.e. 8.9% of total admission) met the criteria of febrile seizure and were hence included in the study. Majority of the cases had Simple febrile Seizure (77%) and the remaining had Complex febrile seizure (23%). The study population was of mixed gender (60% male and 40% female). Mean age of presentation was 23.7 (±11.7) months. The highest prevalence was seen in children < 2 years of age. Mean duration of seizure was 5.11 (±4.84) minutes. URTI and AGE were the leading cause of febrile seizure, with prevalence of 45% and 42% respectively. 10% of children were stunted and 5% of children were wasted. Mean height for age was -0.43 (±1.5) SD and mean weight for height was -0.31 (±1.02) SD. Mean serum sodium, potassium and calcium level were 133 (±2.81) meq/l, 4.4 (±3.0) meq/l and 8.14 (±0.99) mg/dl respectively and mean random blood sugar was 108.4 (±24.17) mg/dl. No association was found between serum sodium level and duration of seizure (correlation=-0.19, p=0.832), serum potassium level and duration seizure (correlation=-0.03, p=0.7). Positive correlation were found between serum calcium level and duration of seizure (correlation=+0.25, p=0.03), as well as blood sugar level and duration of seizure (correlation=+0.19, p=0.027). Conclusion: Since blood sugar and serum calcium levels tended to be high among our study subjects, their impact on duration of febrile seizure should be investigated further. Serum sodium and potassium level had no effect on seizure duration.

Published in	American Journal of Pediatrics (Volume 6, Issue 3)
DOI	10.11648/j.ajp.20200603.38
Page(s)	341-345
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Febrile Seizure, Afebrile Seizure, Stunted, Wasted, Sodium, Potassium, Calcium, Blood Sugar, Hyperglycemia, Hyponatremia, Dyselectrolytemia, AGE, URTI, CNS

References

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APA Style

Nipun Shrestha, Dhruba Shrestha, Ashish Shrestha, Mala Shrestha. (2020). A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration. American Journal of Pediatrics, 6(3), 341-345. https://doi.org/10.11648/j.ajp.20200603.38

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ACS Style

Nipun Shrestha; Dhruba Shrestha; Ashish Shrestha; Mala Shrestha. A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration. Am. J. Pediatr. 2020, 6(3), 341-345. doi: 10.11648/j.ajp.20200603.38

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AMA Style

Nipun Shrestha, Dhruba Shrestha, Ashish Shrestha, Mala Shrestha. A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration. Am J Pediatr. 2020;6(3):341-345. doi: 10.11648/j.ajp.20200603.38

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@article{10.11648/j.ajp.20200603.38,
  author = {Nipun Shrestha and Dhruba Shrestha and Ashish Shrestha and Mala Shrestha},
  title = {A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration},
  journal = {American Journal of Pediatrics},
  volume = {6},
  number = {3},
  pages = {341-345},
  doi = {10.11648/j.ajp.20200603.38},
  url = {https://doi.org/10.11648/j.ajp.20200603.38},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20200603.38},
  abstract = {Background: Febrile Seizure is defined as seizure occurring during febrile episode (body temperature > 100.4°F or 38°C) in a child between 6 to 60 months, in absence of CNS infection, metabolic abnormalities, neurological condition and a history of prior afebrile seizure. Some of the major concerns regarding febrile seizure are its duration and recurrence. Risk factors associated with its duration are poorly understood. Method: A retrospective study was conducted from January to December 2018 among children admitted to Siddhi Memorial Hospital (for Women and Children), Bhaktapur (Nepal) with a diagnosis of febrile seizure. Information on those children, including gender, age of onset, type of seizure, duration of seizure etc., were collected from patient records. Children meeting the standard definition of febrile seizure were included in the study. Data analysis was done using Microsoft Excel and STATA, version 15. A p value Result: A total of 1389 children had been admitted to pediatric department during the study period. Among them, 124 children (i.e. 8.9% of total admission) met the criteria of febrile seizure and were hence included in the study. Majority of the cases had Simple febrile Seizure (77%) and the remaining had Complex febrile seizure (23%). The study population was of mixed gender (60% male and 40% female). Mean age of presentation was 23.7 (±11.7) months. The highest prevalence was seen in children Conclusion: Since blood sugar and serum calcium levels tended to be high among our study subjects, their impact on duration of febrile seizure should be investigated further. Serum sodium and potassium level had no effect on seizure duration.},
 year = {2020}
}

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TY - JOUR
T1 - A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration
AU - Nipun Shrestha
AU - Dhruba Shrestha
AU - Ashish Shrestha
AU - Mala Shrestha
Y1 - 2020/08/20
PY - 2020
N1 - https://doi.org/10.11648/j.ajp.20200603.38
DO - 10.11648/j.ajp.20200603.38
T2 - American Journal of Pediatrics
JF - American Journal of Pediatrics
JO - American Journal of Pediatrics
SP - 341
EP - 345
PB - Science Publishing Group
SN - 2472-0909
UR - https://doi.org/10.11648/j.ajp.20200603.38
AB - Background: Febrile Seizure is defined as seizure occurring during febrile episode (body temperature > 100.4°F or 38°C) in a child between 6 to 60 months, in absence of CNS infection, metabolic abnormalities, neurological condition and a history of prior afebrile seizure. Some of the major concerns regarding febrile seizure are its duration and recurrence. Risk factors associated with its duration are poorly understood. Method: A retrospective study was conducted from January to December 2018 among children admitted to Siddhi Memorial Hospital (for Women and Children), Bhaktapur (Nepal) with a diagnosis of febrile seizure. Information on those children, including gender, age of onset, type of seizure, duration of seizure etc., were collected from patient records. Children meeting the standard definition of febrile seizure were included in the study. Data analysis was done using Microsoft Excel and STATA, version 15. A p value Result: A total of 1389 children had been admitted to pediatric department during the study period. Among them, 124 children (i.e. 8.9% of total admission) met the criteria of febrile seizure and were hence included in the study. Majority of the cases had Simple febrile Seizure (77%) and the remaining had Complex febrile seizure (23%). The study population was of mixed gender (60% male and 40% female). Mean age of presentation was 23.7 (±11.7) months. The highest prevalence was seen in children Conclusion: Since blood sugar and serum calcium levels tended to be high among our study subjects, their impact on duration of febrile seizure should be investigated further. Serum sodium and potassium level had no effect on seizure duration.
VL - 6
IS - 3
ER -

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Author Information

Nipun Shrestha

Siddhi Memorial Hospital (for Women and Children), Bhaktapur, Nepal
Dhruba Shrestha

Siddhi Memorial Hospital (for Women and Children), Bhaktapur, Nepal
Ashish Shrestha

Northampton General Hospital, Northampton, England, United Kingdom
Mala Shrestha

Siddhi Memorial Hospital (for Women and Children), Bhaktapur, Nepal

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APA Style

Nipun Shrestha, Dhruba Shrestha, Ashish Shrestha, Mala Shrestha. (2020). A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration. American Journal of Pediatrics, 6(3), 341-345. https://doi.org/10.11648/j.ajp.20200603.38

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ACS Style

Nipun Shrestha; Dhruba Shrestha; Ashish Shrestha; Mala Shrestha. A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration. Am. J. Pediatr. 2020, 6(3), 341-345. doi: 10.11648/j.ajp.20200603.38

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AMA Style

Nipun Shrestha, Dhruba Shrestha, Ashish Shrestha, Mala Shrestha. A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration. Am J Pediatr. 2020;6(3):341-345. doi: 10.11648/j.ajp.20200603.38

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@article{10.11648/j.ajp.20200603.38,
  author = {Nipun Shrestha and Dhruba Shrestha and Ashish Shrestha and Mala Shrestha},
  title = {A Retrospective Study of Clinical Presentation of Child with Febrile Seizure and Its Duration},
  journal = {American Journal of Pediatrics},
  volume = {6},
  number = {3},
  pages = {341-345},
  doi = {10.11648/j.ajp.20200603.38},
  url = {https://doi.org/10.11648/j.ajp.20200603.38},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20200603.38},
  abstract = {Background: Febrile Seizure is defined as seizure occurring during febrile episode (body temperature > 100.4°F or 38°C) in a child between 6 to 60 months, in absence of CNS infection, metabolic abnormalities, neurological condition and a history of prior afebrile seizure. Some of the major concerns regarding febrile seizure are its duration and recurrence. Risk factors associated with its duration are poorly understood. Method: A retrospective study was conducted from January to December 2018 among children admitted to Siddhi Memorial Hospital (for Women and Children), Bhaktapur (Nepal) with a diagnosis of febrile seizure. Information on those children, including gender, age of onset, type of seizure, duration of seizure etc., were collected from patient records. Children meeting the standard definition of febrile seizure were included in the study. Data analysis was done using Microsoft Excel and STATA, version 15. A p value Result: A total of 1389 children had been admitted to pediatric department during the study period. Among them, 124 children (i.e. 8.9% of total admission) met the criteria of febrile seizure and were hence included in the study. Majority of the cases had Simple febrile Seizure (77%) and the remaining had Complex febrile seizure (23%). The study population was of mixed gender (60% male and 40% female). Mean age of presentation was 23.7 (±11.7) months. The highest prevalence was seen in children Conclusion: Since blood sugar and serum calcium levels tended to be high among our study subjects, their impact on duration of febrile seizure should be investigated further. Serum sodium and potassium level had no effect on seizure duration.},
 year = {2020}
}

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