Introduction: Acute glomerulonephritis includes renal diseases in which immunologic mechanism triggers inflammation and proliferation of glomerular tissue that can result in damage to the basement membrane, proliferation of mesangium, capillary endothelium. Objectives: The objective of this study is to know the clinical profile and immediate outcome of acute glomerulonephritis in hospitalized children. Material & Methods: The study was done in Chittagong Medical College Hospital Pediatric Unit during the period of June 2007 to February 2008. All patients admitted with AGN, with or without complications were included in this study. Diagnostic criteria were scanty urine (infrequent and less than normal in amount as stated by the parents), swelling, high colored urine with or without albuminuria, no past history of similar attack and microscopic or naked eye haematuria. Criteria of discharge from the hospital were absence of puffiness and oedema, adequate urine formation, absence of heart failure and hypertensive encephalopathy. These were taken as clinical recovery. No long-term follow up was done. Results: Seventy-eight cases of acute glomerulonephritis (AGN) in children under 12 years of age were studied. Male to female ration 3:2. Scanty urine (84.0%), puffy face (88.5%) h, haematuria (80.0%), hypertension (82.5%), heart failure (11.5%) convulsion (14%) anuria (3.8%), RBC (92.3%), RBC cast (41%), albumin one (+) (52.6%) two + (14.1%) three + (14.1%), raised s. creatinine was (25.6%), blood urea (26.9%). Four patients were died. Among them three was due to hypertension and heart failure. One due to the development of acute renal failure. History of skin infection like scabies was present in 61.4% patient. Conclusion: Skin infection is the commonest cause of acute glomerulonephritis. Nephritic presentation (scanty urine oedema, haematuria, hypertension and heart failure) was the commonest mode of presentation. Immediate prognosis was excellent- Long term follow up is recommended.
| Published in | American Journal of Pediatrics (Volume 6, Issue 4) |
| DOI | 10.11648/j.ajp.20200604.20 |
| Page(s) | 448-454 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
Acute Glomerulonephritis, Skin Infection, Hospitalized Children, Pediatric, Haematuria
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APA Style
A. N. M. Shahidul Islam Bhuiyan, Zahangir Alam, Khondaker Zahirul Hasan, Md Mostafa Zaman, Md Zakaria. (2020). A Clinical Profile and Immediate Outcome of Acute Glomerulonephritis (AGN) in Hospitalized Children. American Journal of Pediatrics, 6(4), 448-454. https://doi.org/10.11648/j.ajp.20200604.20
ACS Style
A. N. M. Shahidul Islam Bhuiyan; Zahangir Alam; Khondaker Zahirul Hasan; Md Mostafa Zaman; Md Zakaria. A Clinical Profile and Immediate Outcome of Acute Glomerulonephritis (AGN) in Hospitalized Children. Am. J. Pediatr. 2020, 6(4), 448-454. doi: 10.11648/j.ajp.20200604.20
AMA Style
A. N. M. Shahidul Islam Bhuiyan, Zahangir Alam, Khondaker Zahirul Hasan, Md Mostafa Zaman, Md Zakaria. A Clinical Profile and Immediate Outcome of Acute Glomerulonephritis (AGN) in Hospitalized Children. Am J Pediatr. 2020;6(4):448-454. doi: 10.11648/j.ajp.20200604.20
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Download@article{10.11648/j.ajp.20200604.20,
author = {A. N. M. Shahidul Islam Bhuiyan and Zahangir Alam and Khondaker Zahirul Hasan and Md Mostafa Zaman and Md Zakaria},
title = {A Clinical Profile and Immediate Outcome of Acute Glomerulonephritis (AGN) in Hospitalized Children},
journal = {American Journal of Pediatrics},
volume = {6},
number = {4},
pages = {448-454},
doi = {10.11648/j.ajp.20200604.20},
url = {https://doi.org/10.11648/j.ajp.20200604.20},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20200604.20},
abstract = {Introduction: Acute glomerulonephritis includes renal diseases in which immunologic mechanism triggers inflammation and proliferation of glomerular tissue that can result in damage to the basement membrane, proliferation of mesangium, capillary endothelium. Objectives: The objective of this study is to know the clinical profile and immediate outcome of acute glomerulonephritis in hospitalized children. Material & Methods: The study was done in Chittagong Medical College Hospital Pediatric Unit during the period of June 2007 to February 2008. All patients admitted with AGN, with or without complications were included in this study. Diagnostic criteria were scanty urine (infrequent and less than normal in amount as stated by the parents), swelling, high colored urine with or without albuminuria, no past history of similar attack and microscopic or naked eye haematuria. Criteria of discharge from the hospital were absence of puffiness and oedema, adequate urine formation, absence of heart failure and hypertensive encephalopathy. These were taken as clinical recovery. No long-term follow up was done. Results: Seventy-eight cases of acute glomerulonephritis (AGN) in children under 12 years of age were studied. Male to female ration 3:2. Scanty urine (84.0%), puffy face (88.5%) h, haematuria (80.0%), hypertension (82.5%), heart failure (11.5%) convulsion (14%) anuria (3.8%), RBC (92.3%), RBC cast (41%), albumin one (+) (52.6%) two + (14.1%) three + (14.1%), raised s. creatinine was (25.6%), blood urea (26.9%). Four patients were died. Among them three was due to hypertension and heart failure. One due to the development of acute renal failure. History of skin infection like scabies was present in 61.4% patient. Conclusion: Skin infection is the commonest cause of acute glomerulonephritis. Nephritic presentation (scanty urine oedema, haematuria, hypertension and heart failure) was the commonest mode of presentation. Immediate prognosis was excellent- Long term follow up is recommended.},
year = {2020}
}
TY - JOUR T1 - A Clinical Profile and Immediate Outcome of Acute Glomerulonephritis (AGN) in Hospitalized Children AU - A. N. M. Shahidul Islam Bhuiyan AU - Zahangir Alam AU - Khondaker Zahirul Hasan AU - Md Mostafa Zaman AU - Md Zakaria Y1 - 2020/11/04 PY - 2020 N1 - https://doi.org/10.11648/j.ajp.20200604.20 DO - 10.11648/j.ajp.20200604.20 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 448 EP - 454 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20200604.20 AB - Introduction: Acute glomerulonephritis includes renal diseases in which immunologic mechanism triggers inflammation and proliferation of glomerular tissue that can result in damage to the basement membrane, proliferation of mesangium, capillary endothelium. Objectives: The objective of this study is to know the clinical profile and immediate outcome of acute glomerulonephritis in hospitalized children. Material & Methods: The study was done in Chittagong Medical College Hospital Pediatric Unit during the period of June 2007 to February 2008. All patients admitted with AGN, with or without complications were included in this study. Diagnostic criteria were scanty urine (infrequent and less than normal in amount as stated by the parents), swelling, high colored urine with or without albuminuria, no past history of similar attack and microscopic or naked eye haematuria. Criteria of discharge from the hospital were absence of puffiness and oedema, adequate urine formation, absence of heart failure and hypertensive encephalopathy. These were taken as clinical recovery. No long-term follow up was done. Results: Seventy-eight cases of acute glomerulonephritis (AGN) in children under 12 years of age were studied. Male to female ration 3:2. Scanty urine (84.0%), puffy face (88.5%) h, haematuria (80.0%), hypertension (82.5%), heart failure (11.5%) convulsion (14%) anuria (3.8%), RBC (92.3%), RBC cast (41%), albumin one (+) (52.6%) two + (14.1%) three + (14.1%), raised s. creatinine was (25.6%), blood urea (26.9%). Four patients were died. Among them three was due to hypertension and heart failure. One due to the development of acute renal failure. History of skin infection like scabies was present in 61.4% patient. Conclusion: Skin infection is the commonest cause of acute glomerulonephritis. Nephritic presentation (scanty urine oedema, haematuria, hypertension and heart failure) was the commonest mode of presentation. Immediate prognosis was excellent- Long term follow up is recommended. VL - 6 IS - 4 ER -
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