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Prenatal Diagnosis of Type 1c Choledochal Cysts in 1 Month Old Baby

Received: 10 March 2021     Accepted: 30 March 2021     Published: 13 April 2021
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Abstract

Choledochal cysts (CCs) are congenital dilatations of extrahepatic and/or intrahepatic bile ducts. It is a rare biliary entity, in the Asian population, the incidence can be as high as 1:1000 live. We reported case of One-month old baby girl with yellowish skin and acholic stool the baby has been suspected with anechoic abdominal mass at 17 weeks of gestational age using fetal ultrasound. From physical examination, jaundice was seen on the sclera and all over the body. The bowel sound was normal, without distention, without palpable liver nor spleen. The mass was not palpable either. Aspartate transaminase serum (AST), alanine aminotransferase serum (ALT), gamma glutamyl tranferase (GGT), bilirubin level was increased. Ultrasound was performed and revealed extrahepatic dilation to form a saccus in the proximal CBD, according to the picture of type 1 choledocal cyst. The surgeon performed cyst excision and hepatoduodenostomy procedure and found choledochal cyst. Histopathologic examination from cyst confirmed the choledochal cyst. The patient was discharged in good condition. We conclude that Type I choledochal cysts can be identified prenatally during a detailed fetal sonogram. The newborn should be investigated to confirm the diagnosis and undergo cyst excision promptly to reduce the potential for complications.

Published in American Journal of Pediatrics (Volume 7, Issue 2)
DOI 10.11648/j.ajp.20210702.12
Page(s) 49-52
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Choledochal Cyst, Prenatal Diagnosis, Treatment, Surgery

References
[1] García NA, Hinojosa AS, Pardo NG, et al. Prenatal diagnosis of a giant choledochal cyst. J Ped Surg Case Reports. 2016; 4: 1-3.
[2] Eijnden MH, Kleine RH, Blaauw ID, Peeters PG, et al. Choledochal Malformation in Children: Lessons Learned from a Dutch National Study. World J Surg. 2017; 41: 2631–2637.
[3] Soares KC, Goldstein SD, Ghaseb MA, Kamel I, Hackam DJ, Pawlik TM. Pediatric choledochal cysts: diagnosis and current management. Pediatr Surg Int 2017; 33: 637–650.
[4] Soares KC, Arnaoutakis DJ, Kamel I, et al. Choledochal Cysts: Presentation, Clinical Differentiation, and Management. J Am Coll Surg. 2014; 219 (6): 1167-180.
[5] Singham J, Yoshida EM, Scudamore CH. Choledochal cysts Part 1 of 3: Classification and pathogenesis. J can chir. 2009; 52 (5): 440-434.
[6] Gezer HO. Pediatric choledochal cysts: unknowns are decreasing. Intech open. (Acces at 30th August 2020). Available at: http//dx.doi.org/10.5772/intechopen.84301.
[7] Foo DC, Wong KK, Lan LC, et al. Impact of prenatal diagnosis on choledochal cysts benefits of early excision. Journal of Paediatrics and Child Health. 2009; 45: 28–30.
[8] Cannella R, Giambelluca D, Diamarco M, Caruana G, Cutaia G, Midiri M, et al. Congenital Cystic Lesions of the Bile Ducts: imaging-based diagnosis. Current problems in diagnostic radiology. 2019; 49 (4): 285-293.
[9] Lee IH, Kim GJ. Fetal Choledochal Cyst Diagnosed at 22 Weeks of Gestation by Three-Dimensional Ultrasonography: A Case Report. J Korean Med Sci. 2008; 23: 909-11.
[10] Reza M, Nesa NM, Putra IGNS, et al. ype IC Choledochal Cyst Presenting An Extrahepatal Cholestasis In A 3 Year Old Boy. MEDICINA. 2015; 4 (1): 60-56.
[11] Guzman JP, Resurreccion LL, Suntay ML, et al. Comparison between hepaticojejunostomy and hepaticoduodenostomy after excision of choledochal cyst in children: a cohort study. World Jnl Ped Surgery. 2019; 2: e000029.
[12] Buyukyavuz Y, Ekinci S, Ciftci AO, et al. A retrospective study of choledochal cyst: clinical presentation, diagnosis and treatment. The Turkish Journal of Pediatrics. 2003; 45: 321-325.
[13] Mackenzie TC, Howell LJ, Flake AW, et al. The Management of Prenatally Diagnosed Choledochal Cysts. J Pediatr Surg. 2001; 36: 1241-1243.
[14] Cochran ED, Lazow SP, Kim AG, et al. The In-Utero Diagnosis Of Choledochal Cyst: Can Postnatal Imaging Predict Benefit From Early Surgical Intervention? The Journal of Maternal-Fetal & Neonatal Medicine. 2019; 1: 1-5.
[15] Baez HS, Ramírez PC, Ixtabal EM, et al. Treatment of choledochal cyst in a pediatric population. A single institution experience of 15-years. Case series. Annals of Medicine and Surgery. 2016; 5: 81-85.
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  • APA Style

    Ida Ayu Agung Wijayanti, Ni Nyoman Metriani Nesa, I Gusti Ngurah Sanjaya Putra, I Putu Gede Karyana, Kadek Deddy Ariyanta, et al. (2021). Prenatal Diagnosis of Type 1c Choledochal Cysts in 1 Month Old Baby. American Journal of Pediatrics, 7(2), 49-52. https://doi.org/10.11648/j.ajp.20210702.12

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    ACS Style

    Ida Ayu Agung Wijayanti; Ni Nyoman Metriani Nesa; I Gusti Ngurah Sanjaya Putra; I Putu Gede Karyana; Kadek Deddy Ariyanta, et al. Prenatal Diagnosis of Type 1c Choledochal Cysts in 1 Month Old Baby. Am. J. Pediatr. 2021, 7(2), 49-52. doi: 10.11648/j.ajp.20210702.12

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    AMA Style

    Ida Ayu Agung Wijayanti, Ni Nyoman Metriani Nesa, I Gusti Ngurah Sanjaya Putra, I Putu Gede Karyana, Kadek Deddy Ariyanta, et al. Prenatal Diagnosis of Type 1c Choledochal Cysts in 1 Month Old Baby. Am J Pediatr. 2021;7(2):49-52. doi: 10.11648/j.ajp.20210702.12

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  • @article{10.11648/j.ajp.20210702.12,
      author = {Ida Ayu Agung Wijayanti and Ni Nyoman Metriani Nesa and I Gusti Ngurah Sanjaya Putra and I Putu Gede Karyana and Kadek Deddy Ariyanta and I Made Dharmajaya and Ni Made Mahastuti},
      title = {Prenatal Diagnosis of Type 1c Choledochal Cysts in 1 Month Old Baby},
      journal = {American Journal of Pediatrics},
      volume = {7},
      number = {2},
      pages = {49-52},
      doi = {10.11648/j.ajp.20210702.12},
      url = {https://doi.org/10.11648/j.ajp.20210702.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20210702.12},
      abstract = {Choledochal cysts (CCs) are congenital dilatations of extrahepatic and/or intrahepatic bile ducts. It is a rare biliary entity, in the Asian population, the incidence can be as high as 1:1000 live. We reported case of One-month old baby girl with yellowish skin and acholic stool the baby has been suspected with anechoic abdominal mass at 17 weeks of gestational age using fetal ultrasound. From physical examination, jaundice was seen on the sclera and all over the body. The bowel sound was normal, without distention, without palpable liver nor spleen. The mass was not palpable either. Aspartate transaminase serum (AST), alanine aminotransferase serum (ALT), gamma glutamyl tranferase (GGT), bilirubin level was increased. Ultrasound was performed and revealed extrahepatic dilation to form a saccus in the proximal CBD, according to the picture of type 1 choledocal cyst. The surgeon performed cyst excision and hepatoduodenostomy procedure and found choledochal cyst. Histopathologic examination from cyst confirmed the choledochal cyst. The patient was discharged in good condition. We conclude that Type I choledochal cysts can be identified prenatally during a detailed fetal sonogram. The newborn should be investigated to confirm the diagnosis and undergo cyst excision promptly to reduce the potential for complications.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Prenatal Diagnosis of Type 1c Choledochal Cysts in 1 Month Old Baby
    AU  - Ida Ayu Agung Wijayanti
    AU  - Ni Nyoman Metriani Nesa
    AU  - I Gusti Ngurah Sanjaya Putra
    AU  - I Putu Gede Karyana
    AU  - Kadek Deddy Ariyanta
    AU  - I Made Dharmajaya
    AU  - Ni Made Mahastuti
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    N1  - https://doi.org/10.11648/j.ajp.20210702.12
    DO  - 10.11648/j.ajp.20210702.12
    T2  - American Journal of Pediatrics
    JF  - American Journal of Pediatrics
    JO  - American Journal of Pediatrics
    SP  - 49
    EP  - 52
    PB  - Science Publishing Group
    SN  - 2472-0909
    UR  - https://doi.org/10.11648/j.ajp.20210702.12
    AB  - Choledochal cysts (CCs) are congenital dilatations of extrahepatic and/or intrahepatic bile ducts. It is a rare biliary entity, in the Asian population, the incidence can be as high as 1:1000 live. We reported case of One-month old baby girl with yellowish skin and acholic stool the baby has been suspected with anechoic abdominal mass at 17 weeks of gestational age using fetal ultrasound. From physical examination, jaundice was seen on the sclera and all over the body. The bowel sound was normal, without distention, without palpable liver nor spleen. The mass was not palpable either. Aspartate transaminase serum (AST), alanine aminotransferase serum (ALT), gamma glutamyl tranferase (GGT), bilirubin level was increased. Ultrasound was performed and revealed extrahepatic dilation to form a saccus in the proximal CBD, according to the picture of type 1 choledocal cyst. The surgeon performed cyst excision and hepatoduodenostomy procedure and found choledochal cyst. Histopathologic examination from cyst confirmed the choledochal cyst. The patient was discharged in good condition. We conclude that Type I choledochal cysts can be identified prenatally during a detailed fetal sonogram. The newborn should be investigated to confirm the diagnosis and undergo cyst excision promptly to reduce the potential for complications.
    VL  - 7
    IS  - 2
    ER  - 

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Author Information
  • Department of Child Health, Faculty of Medicine, Udayana University/Sanglah Hospital, Denpasar, Indonesia

  • Department of Child Health, Faculty of Medicine, Udayana University/Sanglah Hospital, Denpasar, Indonesia

  • Department of Child Health, Faculty of Medicine, Udayana University/Sanglah Hospital, Denpasar, Indonesia

  • Department of Child Health, Faculty of Medicine, Udayana University/Sanglah Hospital, Denpasar, Indonesia

  • Department of Surgery, Faculty of Medicine, Udayana University/Sanglah Hospital, Denpasar, Indonesia

  • Department of Surgery, Faculty of Medicine, Udayana University/Sanglah Hospital, Denpasar, Indonesia

  • Department of Anatomical Pathology, Faculty of Medicine, Udayana University/Sanglah Hospital, Denpasar, Indonesia

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