Ischemic stroke (AI) is becoming an increasingly important and urgent problem in pediatrics due to the occurrence of neurological disorders that affect the quality of life and limit the social adaptation of a child. The clinical picture of ischemic stroke in pediatric practice differs from the manifestation of this pathology in adult patients. Children have special risk factors for the development of IS. In pediatric oncology, there are such factors like invasive tumor growth, the development of tumor embolism, and blood clotting disorders. Side effects of anticancer treatment occupy a special place in the development of IS. The relationship between post-radiation arteriopathies and ischemic stroke has been more studied among cancer patients who underwent neck irradiation. In children, it was found that after radiation therapy to the head and neck region and, thus, the risk of ischemic stroke in childhood increases. This review is devoted to the possible pathophysiological causes and mechanisms of stroke in children with head and neck tumors. In addition, descriptions of clinical cases of patients with ischemic stroke in the course of anticancer treatment are presented.
| Published in | American Journal of Pediatrics (Volume 7, Issue 3) |
| DOI | 10.11648/j.ajp.20210703.24 |
| Page(s) | 163-169 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Children's Arterial Ischemic Stroke, Chemotherapy, Radiation Therapy, Pediatric Oncology
| [1] | Ischemic stroke (AI) is becoming an increasingly important and urgent problem in pediatrics due to the occurrence of neurological disorders that affect the quality of life and limit the social adaptation of a child. The clinical picture of ischemic stroke in pediatric practice differs from the manifestation of this pathology in adult patients. Children have special risk factors for the development of IS. In pediatric oncology, there are such factors like invasive tumor growth, the development of tumor embolism, and blood clotting disorders. Side effects of anticancer treatment occupy a special place in the development of IS. The relationship between post-radiation arteriopathies and ischemic stroke has been more studied among cancer patients who underwent neck irradiation. In children, it was found that after radiation therapy to the head and neck region and, thus, the risk of ischemic stroke in childhood increases. This review is devoted to the possible pathophysiological causes and mechanisms of stroke in children with head and neck tumors. In addition, descriptions of clinical cases of patients with ischemic stroke in the course of anticancer treatment are presented. |
APA Style
Anastasia D. Rodina, Vladimir Sh. Vanesyan, Tatiana V. Gorbunova, Natalia V. Ivanova, Vladimir G. Polyakov. (2021). Risk Factors of Ischemic Stroke in Children with Head and Neck Tumors: A Clinical Case Description with a Literature Review. American Journal of Pediatrics, 7(3), 163-169. https://doi.org/10.11648/j.ajp.20210703.24
ACS Style
Anastasia D. Rodina; Vladimir Sh. Vanesyan; Tatiana V. Gorbunova; Natalia V. Ivanova; Vladimir G. Polyakov. Risk Factors of Ischemic Stroke in Children with Head and Neck Tumors: A Clinical Case Description with a Literature Review. Am. J. Pediatr. 2021, 7(3), 163-169. doi: 10.11648/j.ajp.20210703.24
AMA Style
Anastasia D. Rodina, Vladimir Sh. Vanesyan, Tatiana V. Gorbunova, Natalia V. Ivanova, Vladimir G. Polyakov. Risk Factors of Ischemic Stroke in Children with Head and Neck Tumors: A Clinical Case Description with a Literature Review. Am J Pediatr. 2021;7(3):163-169. doi: 10.11648/j.ajp.20210703.24
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Download@article{10.11648/j.ajp.20210703.24,
author = {Anastasia D. Rodina and Vladimir Sh. Vanesyan and Tatiana V. Gorbunova and Natalia V. Ivanova and Vladimir G. Polyakov},
title = {Risk Factors of Ischemic Stroke in Children with Head and Neck Tumors: A Clinical Case Description with a Literature Review},
journal = {American Journal of Pediatrics},
volume = {7},
number = {3},
pages = {163-169},
doi = {10.11648/j.ajp.20210703.24},
url = {https://doi.org/10.11648/j.ajp.20210703.24},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20210703.24},
abstract = {Ischemic stroke (AI) is becoming an increasingly important and urgent problem in pediatrics due to the occurrence of neurological disorders that affect the quality of life and limit the social adaptation of a child. The clinical picture of ischemic stroke in pediatric practice differs from the manifestation of this pathology in adult patients. Children have special risk factors for the development of IS. In pediatric oncology, there are such factors like invasive tumor growth, the development of tumor embolism, and blood clotting disorders. Side effects of anticancer treatment occupy a special place in the development of IS. The relationship between post-radiation arteriopathies and ischemic stroke has been more studied among cancer patients who underwent neck irradiation. In children, it was found that after radiation therapy to the head and neck region and, thus, the risk of ischemic stroke in childhood increases. This review is devoted to the possible pathophysiological causes and mechanisms of stroke in children with head and neck tumors. In addition, descriptions of clinical cases of patients with ischemic stroke in the course of anticancer treatment are presented.},
year = {2021}
}
TY - JOUR T1 - Risk Factors of Ischemic Stroke in Children with Head and Neck Tumors: A Clinical Case Description with a Literature Review AU - Anastasia D. Rodina AU - Vladimir Sh. Vanesyan AU - Tatiana V. Gorbunova AU - Natalia V. Ivanova AU - Vladimir G. Polyakov Y1 - 2021/08/31 PY - 2021 N1 - https://doi.org/10.11648/j.ajp.20210703.24 DO - 10.11648/j.ajp.20210703.24 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 163 EP - 169 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20210703.24 AB - Ischemic stroke (AI) is becoming an increasingly important and urgent problem in pediatrics due to the occurrence of neurological disorders that affect the quality of life and limit the social adaptation of a child. The clinical picture of ischemic stroke in pediatric practice differs from the manifestation of this pathology in adult patients. Children have special risk factors for the development of IS. In pediatric oncology, there are such factors like invasive tumor growth, the development of tumor embolism, and blood clotting disorders. Side effects of anticancer treatment occupy a special place in the development of IS. The relationship between post-radiation arteriopathies and ischemic stroke has been more studied among cancer patients who underwent neck irradiation. In children, it was found that after radiation therapy to the head and neck region and, thus, the risk of ischemic stroke in childhood increases. This review is devoted to the possible pathophysiological causes and mechanisms of stroke in children with head and neck tumors. In addition, descriptions of clinical cases of patients with ischemic stroke in the course of anticancer treatment are presented. VL - 7 IS - 3 ER -
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