Influence of Birth Season Climate on Adult Total Serum IgE Levels

John Kelly Smith

doi:doi:10.11648/j.ajp.20220802.25

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Influence of Birth Season Climate on Adult Total Serum IgE Levels

John Kelly Smith

Published in American Journal of Pediatrics (Volume 8, Issue 2)

Received: 22 May 2022 Accepted: 10 June 2022 Published: 16 June 2022

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Abstract

Background: The effect of birth season climate on adult IgE-mediated respiratory disease is an important public health issue. Objective: To determine the effect of birth season climate on adult total serum IgE (TSIgE) levels. Study design: The study is a retrospective chart review with the following inclusion criteria: TSIgE measurement, age ≥ 16, and northeastern Tennessee birthplace. Main outcome measures include TSIgE levels, birth season climatic conditions, and regional pollen-producing plant and pollen counts. Results: The records of 1,274 women (mean age 40.8 ± 17.5, age range 16-96) and 762 men (mean age 38.1 ± 17, age range 16-82) seen in our Allergy Clinic were reviewed. Persons born in the spring and summer, the seasons with the highest pollen counts and the most favorable climatic conditions for plant growth, had nearly twice the odds of having TSIgE levels > 1σ above the mean of the study group when compared to those born in the fall or winter (odds ratio (OR) 1.75, 95% confidence interval (CI) 0.96-3.17 and OR 1.93, 95% CI 1.04-3.57, respectively); odds were highest for those born in March (OR 2.55, 95% CI 1.37-4.74) and July (OR 2.38, 95% CI 1.25-4.51) and lowest for those born in November (OR 0.11, 95% CI 0.0068-1.79). When averaged over the 95-years of study and five 30-year climate cycles TSIgE levels increased linearly as the seasons progressed from fall to summer (r² = 0.9475, P = 0.0266). Of the climatic factors, TSIgE levels correlated most strongly with levels of precipitation (r² = 0.9145, P = 0.0437). Conclusion: Climatic conditions that increase birth season exposure to environmental allergens may have a life-long effect on TSIgE production.

Published in	American Journal of Pediatrics (Volume 8, Issue 2)
DOI	10.11648/j.ajp.20220802.25
Page(s)	137-140
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Total Serum IgE, Birth Month, Birth Season, Birth Climate, Neonates, Allergy

References

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John Kelly Smith. (2022). Influence of Birth Season Climate on Adult Total Serum IgE Levels. American Journal of Pediatrics, 8(2), 137-140. https://doi.org/10.11648/j.ajp.20220802.25

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ACS Style

John Kelly Smith. Influence of Birth Season Climate on Adult Total Serum IgE Levels. Am. J. Pediatr. 2022, 8(2), 137-140. doi: 10.11648/j.ajp.20220802.25

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John Kelly Smith. Influence of Birth Season Climate on Adult Total Serum IgE Levels. Am J Pediatr. 2022;8(2):137-140. doi: 10.11648/j.ajp.20220802.25

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@article{10.11648/j.ajp.20220802.25,
  author = {John Kelly Smith},
  title = {Influence of Birth Season Climate on Adult Total Serum IgE Levels},
  journal = {American Journal of Pediatrics},
  volume = {8},
  number = {2},
  pages = {137-140},
  doi = {10.11648/j.ajp.20220802.25},
  url = {https://doi.org/10.11648/j.ajp.20220802.25},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20220802.25},
  abstract = {Background: The effect of birth season climate on adult IgE-mediated respiratory disease is an important public health issue. Objective: To determine the effect of birth season climate on adult total serum IgE (TSIgE) levels. Study design: The study is a retrospective chart review with the following inclusion criteria: TSIgE measurement, age ≥ 16, and northeastern Tennessee birthplace. Main outcome measures include TSIgE levels, birth season climatic conditions, and regional pollen-producing plant and pollen counts. Results: The records of 1,274 women (mean age 40.8 ± 17.5, age range 16-96) and 762 men (mean age 38.1 ± 17, age range 16-82) seen in our Allergy Clinic were reviewed. Persons born in the spring and summer, the seasons with the highest pollen counts and the most favorable climatic conditions for plant growth, had nearly twice the odds of having TSIgE levels > 1σ above the mean of the study group when compared to those born in the fall or winter (odds ratio (OR) 1.75, 95% confidence interval (CI) 0.96-3.17 and OR 1.93, 95% CI 1.04-3.57, respectively); odds were highest for those born in March (OR 2.55, 95% CI 1.37-4.74) and July (OR 2.38, 95% CI 1.25-4.51) and lowest for those born in November (OR 0.11, 95% CI 0.0068-1.79). When averaged over the 95-years of study and five 30-year climate cycles TSIgE levels increased linearly as the seasons progressed from fall to summer (r2 = 0.9475, P = 0.0266). Of the climatic factors, TSIgE levels correlated most strongly with levels of precipitation (r2 = 0.9145, P = 0.0437). Conclusion: Climatic conditions that increase birth season exposure to environmental allergens may have a life-long effect on TSIgE production.},
 year = {2022}
}

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TY  - JOUR
T1  - Influence of Birth Season Climate on Adult Total Serum IgE Levels
AU  - John Kelly Smith
Y1  - 2022/06/16
PY  - 2022
N1  - https://doi.org/10.11648/j.ajp.20220802.25
DO  - 10.11648/j.ajp.20220802.25
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 137
EP  - 140
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20220802.25
AB  - Background: The effect of birth season climate on adult IgE-mediated respiratory disease is an important public health issue. Objective: To determine the effect of birth season climate on adult total serum IgE (TSIgE) levels. Study design: The study is a retrospective chart review with the following inclusion criteria: TSIgE measurement, age ≥ 16, and northeastern Tennessee birthplace. Main outcome measures include TSIgE levels, birth season climatic conditions, and regional pollen-producing plant and pollen counts. Results: The records of 1,274 women (mean age 40.8 ± 17.5, age range 16-96) and 762 men (mean age 38.1 ± 17, age range 16-82) seen in our Allergy Clinic were reviewed. Persons born in the spring and summer, the seasons with the highest pollen counts and the most favorable climatic conditions for plant growth, had nearly twice the odds of having TSIgE levels > 1σ above the mean of the study group when compared to those born in the fall or winter (odds ratio (OR) 1.75, 95% confidence interval (CI) 0.96-3.17 and OR 1.93, 95% CI 1.04-3.57, respectively); odds were highest for those born in March (OR 2.55, 95% CI 1.37-4.74) and July (OR 2.38, 95% CI 1.25-4.51) and lowest for those born in November (OR 0.11, 95% CI 0.0068-1.79). When averaged over the 95-years of study and five 30-year climate cycles TSIgE levels increased linearly as the seasons progressed from fall to summer (r2 = 0.9475, P = 0.0266). Of the climatic factors, TSIgE levels correlated most strongly with levels of precipitation (r2 = 0.9145, P = 0.0437). Conclusion: Climatic conditions that increase birth season exposure to environmental allergens may have a life-long effect on TSIgE production.
VL  - 8
IS  - 2
ER  -

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Author Information

John Kelly Smith

Departments of Academic Affairs and Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, USA

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John Kelly Smith. (2022). Influence of Birth Season Climate on Adult Total Serum IgE Levels. American Journal of Pediatrics, 8(2), 137-140. https://doi.org/10.11648/j.ajp.20220802.25

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ACS Style

John Kelly Smith. Influence of Birth Season Climate on Adult Total Serum IgE Levels. Am. J. Pediatr. 2022, 8(2), 137-140. doi: 10.11648/j.ajp.20220802.25

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AMA Style

John Kelly Smith. Influence of Birth Season Climate on Adult Total Serum IgE Levels. Am J Pediatr. 2022;8(2):137-140. doi: 10.11648/j.ajp.20220802.25

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@article{10.11648/j.ajp.20220802.25,
  author = {John Kelly Smith},
  title = {Influence of Birth Season Climate on Adult Total Serum IgE Levels},
  journal = {American Journal of Pediatrics},
  volume = {8},
  number = {2},
  pages = {137-140},
  doi = {10.11648/j.ajp.20220802.25},
  url = {https://doi.org/10.11648/j.ajp.20220802.25},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20220802.25},
  abstract = {Background: The effect of birth season climate on adult IgE-mediated respiratory disease is an important public health issue. Objective: To determine the effect of birth season climate on adult total serum IgE (TSIgE) levels. Study design: The study is a retrospective chart review with the following inclusion criteria: TSIgE measurement, age ≥ 16, and northeastern Tennessee birthplace. Main outcome measures include TSIgE levels, birth season climatic conditions, and regional pollen-producing plant and pollen counts. Results: The records of 1,274 women (mean age 40.8 ± 17.5, age range 16-96) and 762 men (mean age 38.1 ± 17, age range 16-82) seen in our Allergy Clinic were reviewed. Persons born in the spring and summer, the seasons with the highest pollen counts and the most favorable climatic conditions for plant growth, had nearly twice the odds of having TSIgE levels > 1σ above the mean of the study group when compared to those born in the fall or winter (odds ratio (OR) 1.75, 95% confidence interval (CI) 0.96-3.17 and OR 1.93, 95% CI 1.04-3.57, respectively); odds were highest for those born in March (OR 2.55, 95% CI 1.37-4.74) and July (OR 2.38, 95% CI 1.25-4.51) and lowest for those born in November (OR 0.11, 95% CI 0.0068-1.79). When averaged over the 95-years of study and five 30-year climate cycles TSIgE levels increased linearly as the seasons progressed from fall to summer (r2 = 0.9475, P = 0.0266). Of the climatic factors, TSIgE levels correlated most strongly with levels of precipitation (r2 = 0.9145, P = 0.0437). Conclusion: Climatic conditions that increase birth season exposure to environmental allergens may have a life-long effect on TSIgE production.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Influence of Birth Season Climate on Adult Total Serum IgE Levels
AU  - John Kelly Smith
Y1  - 2022/06/16
PY  - 2022
N1  - https://doi.org/10.11648/j.ajp.20220802.25
DO  - 10.11648/j.ajp.20220802.25
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 137
EP  - 140
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20220802.25
AB  - Background: The effect of birth season climate on adult IgE-mediated respiratory disease is an important public health issue. Objective: To determine the effect of birth season climate on adult total serum IgE (TSIgE) levels. Study design: The study is a retrospective chart review with the following inclusion criteria: TSIgE measurement, age ≥ 16, and northeastern Tennessee birthplace. Main outcome measures include TSIgE levels, birth season climatic conditions, and regional pollen-producing plant and pollen counts. Results: The records of 1,274 women (mean age 40.8 ± 17.5, age range 16-96) and 762 men (mean age 38.1 ± 17, age range 16-82) seen in our Allergy Clinic were reviewed. Persons born in the spring and summer, the seasons with the highest pollen counts and the most favorable climatic conditions for plant growth, had nearly twice the odds of having TSIgE levels > 1σ above the mean of the study group when compared to those born in the fall or winter (odds ratio (OR) 1.75, 95% confidence interval (CI) 0.96-3.17 and OR 1.93, 95% CI 1.04-3.57, respectively); odds were highest for those born in March (OR 2.55, 95% CI 1.37-4.74) and July (OR 2.38, 95% CI 1.25-4.51) and lowest for those born in November (OR 0.11, 95% CI 0.0068-1.79). When averaged over the 95-years of study and five 30-year climate cycles TSIgE levels increased linearly as the seasons progressed from fall to summer (r2 = 0.9475, P = 0.0266). Of the climatic factors, TSIgE levels correlated most strongly with levels of precipitation (r2 = 0.9145, P = 0.0437). Conclusion: Climatic conditions that increase birth season exposure to environmental allergens may have a life-long effect on TSIgE production.
VL  - 8
IS  - 2
ER  -

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