The cerebral venous system is an unusual site for thrombosis. It is a rare pathology in children, with a considerable risk of morbidity and mortality in the absence of specific treatment. The incidence has increased over the last few decades due to improvements in neuroradiological techniques. Clinical features range from seizures, headache and respiratory distress to threatening focal neurological deficits and comatose state. The risk factors are age-dependent, frequently multiple and different from those reported in adults. Infections are the most common predisposing factor both in neonates and older children, followed by hypercoagulable/hematological states, dehydration and various other conditions. In majority of cases, it results from combination of prothombotic risk factors with or without underlying clinical condition. The prognosis is favorable in most cases if the diagnosis is made quickly and treatment is initiated promptly, although acute complications or chronic disability still occur in a quarter of patients. The mainstay of treatment is anticoagulation, which is needed to stop the clot spreading and recanalize it. Endovascular procedures are reserved for patients with a particularly severe presentation or rapidly developing neurological symptoms despite appropriate anticoagulation, although data from clinical trials is lacking. The aim of this work is to study the clinical, etiological, therapeutic and evolutionary characteristics of cerebral venous thrombosis (CVT) in the pediatric population.
| Published in | American Journal of Pediatrics (Volume 10, Issue 3) |
| DOI | 10.11648/j.ajp.20241003.17 |
| Page(s) | 147-151 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Thrombosis, Cerebral, Venous, Imagery, Anticoagulation, Evolution
| [1] | Aude Triquenot. Department of Neurology, Rouen University Hospital, 1 rue de Germont, 76000 Rouen. January 2007 > notebook 2. |
| [2] | Leleu M, Laruelle B, Paulmin C, Ceniccola E. Venous thrombosis in pediatrics. Venous thrombosis in children. March2023. |
| [3] | Baddouh N, El Bakri S, Draiss G. Cerebral venous thrombosis in children. Published online 2019 Jan. 15. |
| [4] | Christine Heller, Achim Heinecke, Ralf Junker, Ralf Knöfler, Andrea Kosch, Karin Kurnik, Rosemarie Schobess, Arnold von Eckardstein, Ronald Sträter, Barbara Zieger, Ulrike Nowak-Göttl; Childhood Stroke Study Group. Cerebral venous thrombosis in children: a multifactorial origin 2003 Sep 16; 108(11): 1362-7. |
| [5] | Coutinho JM, Ferro JM, Canhao P, et al. Unfractionated or low molecular weight heparin for the treatment of cerebral venous thrombosis. Stroke. 2010; 41(11): 257580. |
| [6] | Pawan Saraswat, Sandeep Kumar Baranwal, Aditi Agarwal. Rajniti Prasad, Ankur Singh. Cerebral venous sinus thrombosis in children – A series of seven cases. MARCH 2024. International Journal of Scientific Research |
| [7] | Pruthvi Patel, Shirley M Gandhi, Philip P Breton and Tetiana Litvinchuk4. Pediatric Cerebral Venous Sinus Thrombosis: A Case Report. Published online 2024 Feb 16. |
| [8] | Capecchi M, Abbattista M, MartinelliI, Bianchi Bonomi A. Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy Cerebral venous sinus thrombosis. 2018 Oct; 16(10): 1918-1931. |
| [9] |
Juan Sebastian Proaño, Paul A Martinez, Prithvi Sendi, Balagangadhar R Totapally. Characteristics and Outcomes of Children with Cerebral Sinus Venous Thrombosis. 2023 Oct; 39(2): 331-338.
https://doi.org/10.1007/s12028-023-01765-7 Epub 2023 Jul 12 |
| [10] | Jackson BF, Porcher FK, Zapton DT, Losek JD. Cerebral sinovenous thrombosis in children: diagnosis and treatment. Pediatr Emerg Care. 2011 Sep; 27(9): 874-80; quiz 881-3 |
APA Style
Menjel, I., Benmoussa, A. Y., Harim, F., Chahid, I., Abkari, A. (2024). Cerebral Venous Thrombosis in Children: About 3 Cases. American Journal of Pediatrics, 10(3), 147-151. https://doi.org/10.11648/j.ajp.20241003.17
ACS Style
Menjel, I.; Benmoussa, A. Y.; Harim, F.; Chahid, I.; Abkari, A. Cerebral Venous Thrombosis in Children: About 3 Cases. Am. J. Pediatr. 2024, 10(3), 147-151. doi: 10.11648/j.ajp.20241003.17
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ajp.20241003.17,
author = {Imane Menjel and Abdelhakim Youssef Benmoussa and Fatima Harim and Imane Chahid and Abdelhak Abkari},
title = {Cerebral Venous Thrombosis in Children: About 3 Cases
},
journal = {American Journal of Pediatrics},
volume = {10},
number = {3},
pages = {147-151},
doi = {10.11648/j.ajp.20241003.17},
url = {https://doi.org/10.11648/j.ajp.20241003.17},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20241003.17},
abstract = {The cerebral venous system is an unusual site for thrombosis. It is a rare pathology in children, with a considerable risk of morbidity and mortality in the absence of specific treatment. The incidence has increased over the last few decades due to improvements in neuroradiological techniques. Clinical features range from seizures, headache and respiratory distress to threatening focal neurological deficits and comatose state. The risk factors are age-dependent, frequently multiple and different from those reported in adults. Infections are the most common predisposing factor both in neonates and older children, followed by hypercoagulable/hematological states, dehydration and various other conditions. In majority of cases, it results from combination of prothombotic risk factors with or without underlying clinical condition. The prognosis is favorable in most cases if the diagnosis is made quickly and treatment is initiated promptly, although acute complications or chronic disability still occur in a quarter of patients. The mainstay of treatment is anticoagulation, which is needed to stop the clot spreading and recanalize it. Endovascular procedures are reserved for patients with a particularly severe presentation or rapidly developing neurological symptoms despite appropriate anticoagulation, although data from clinical trials is lacking. The aim of this work is to study the clinical, etiological, therapeutic and evolutionary characteristics of cerebral venous thrombosis (CVT) in the pediatric population.
},
year = {2024}
}
TY - JOUR T1 - Cerebral Venous Thrombosis in Children: About 3 Cases AU - Imane Menjel AU - Abdelhakim Youssef Benmoussa AU - Fatima Harim AU - Imane Chahid AU - Abdelhak Abkari Y1 - 2024/08/27 PY - 2024 N1 - https://doi.org/10.11648/j.ajp.20241003.17 DO - 10.11648/j.ajp.20241003.17 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 147 EP - 151 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20241003.17 AB - The cerebral venous system is an unusual site for thrombosis. It is a rare pathology in children, with a considerable risk of morbidity and mortality in the absence of specific treatment. The incidence has increased over the last few decades due to improvements in neuroradiological techniques. Clinical features range from seizures, headache and respiratory distress to threatening focal neurological deficits and comatose state. The risk factors are age-dependent, frequently multiple and different from those reported in adults. Infections are the most common predisposing factor both in neonates and older children, followed by hypercoagulable/hematological states, dehydration and various other conditions. In majority of cases, it results from combination of prothombotic risk factors with or without underlying clinical condition. The prognosis is favorable in most cases if the diagnosis is made quickly and treatment is initiated promptly, although acute complications or chronic disability still occur in a quarter of patients. The mainstay of treatment is anticoagulation, which is needed to stop the clot spreading and recanalize it. Endovascular procedures are reserved for patients with a particularly severe presentation or rapidly developing neurological symptoms despite appropriate anticoagulation, although data from clinical trials is lacking. The aim of this work is to study the clinical, etiological, therapeutic and evolutionary characteristics of cerebral venous thrombosis (CVT) in the pediatric population. VL - 10 IS - 3 ER -
Neuropediatrics Unit, Peadiatrics’3 of the Abderrahim El Harrouchi Mother and Child Hospital, Casablanca, Morocco
Neuropediatrics Unit, Peadiatrics’3 of the Abderrahim El Harrouchi Mother and Child Hospital, Casablanca, Morocco
Neuropediatrics Unit, Peadiatrics’3 of the Abderrahim El Harrouchi Mother and Child Hospital, Casablanca, Morocco
Neuropediatrics Unit, Peadiatrics’3 of the Abderrahim El Harrouchi Mother and Child Hospital, Casablanca, Morocco
Neuropediatrics Unit, Peadiatrics’3 of the Abderrahim El Harrouchi Mother and Child Hospital, Casablanca, Morocco
Information