DNA microarrays are technology that measure the expression level of thousands of genes at the same time. They need become avital tool for a good kind of biological experiments. one among the most common goals of polymer microarray experiments is to spot genes related to biological processes of interest. DNA Microarray is one such technology that allows the researchers to analyze and address problems that were once thought to be non traceable. This technology has scepter the scientific community to manage the elemental aspects underlining the expansion and development of life, additionally on explore the genetic causes of anomalies occurring within the functioning of organisms. Microarrays area unit vital as a result of they possess a large variety of genes and additionally owingto their transportable size. An important implication of the fundamental dogma of molecular biology is that there should be a strong association between the presence of a given protein in a cell and the presence of the mRNA sequence that is transcribed to build that protein. If a protein is active in a given cell, there should be a large number of copies of the mRNA sequence corresponding to that protein. Conversely, if a protein is not active in a cell, there should be few copies of the corresponding mRNA sequence. Thus, DNA microarrays attempt to evaluate the presence or absence of proteins in a cell and their relative abundance by measuring the relative abundance of the corresponding mRNA sequences. This review addresses the potential uses of DNA microarray technology, principle of the technology, its application and limitation of the technology.
| Published in | American Journal of Zoology (Volume 2, Issue 4) |
| DOI | 10.11648/j.ajz.20190204.11 |
| Page(s) | 44-50 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
DNA Microarray, Protein Microarray, Hybridization, cDNA
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APA Style
Takale Worku, Demessa Negassu. (2020). Review on DNA Micro Array Technologyand Its Application. American Journal of Zoology, 2(4), 44-50. https://doi.org/10.11648/j.ajz.20190204.11
ACS Style
Takale Worku; Demessa Negassu. Review on DNA Micro Array Technologyand Its Application. Am. J. Zool. 2020, 2(4), 44-50. doi: 10.11648/j.ajz.20190204.11
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Download@article{10.11648/j.ajz.20190204.11,
author = {Takale Worku and Demessa Negassu},
title = {Review on DNA Micro Array Technologyand Its Application},
journal = {American Journal of Zoology},
volume = {2},
number = {4},
pages = {44-50},
doi = {10.11648/j.ajz.20190204.11},
url = {https://doi.org/10.11648/j.ajz.20190204.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajz.20190204.11},
abstract = {DNA microarrays are technology that measure the expression level of thousands of genes at the same time. They need become avital tool for a good kind of biological experiments. one among the most common goals of polymer microarray experiments is to spot genes related to biological processes of interest. DNA Microarray is one such technology that allows the researchers to analyze and address problems that were once thought to be non traceable. This technology has scepter the scientific community to manage the elemental aspects underlining the expansion and development of life, additionally on explore the genetic causes of anomalies occurring within the functioning of organisms. Microarrays area unit vital as a result of they possess a large variety of genes and additionally owingto their transportable size. An important implication of the fundamental dogma of molecular biology is that there should be a strong association between the presence of a given protein in a cell and the presence of the mRNA sequence that is transcribed to build that protein. If a protein is active in a given cell, there should be a large number of copies of the mRNA sequence corresponding to that protein. Conversely, if a protein is not active in a cell, there should be few copies of the corresponding mRNA sequence. Thus, DNA microarrays attempt to evaluate the presence or absence of proteins in a cell and their relative abundance by measuring the relative abundance of the corresponding mRNA sequences. This review addresses the potential uses of DNA microarray technology, principle of the technology, its application and limitation of the technology.},
year = {2020}
}
TY - JOUR T1 - Review on DNA Micro Array Technologyand Its Application AU - Takale Worku AU - Demessa Negassu Y1 - 2020/01/06 PY - 2020 N1 - https://doi.org/10.11648/j.ajz.20190204.11 DO - 10.11648/j.ajz.20190204.11 T2 - American Journal of Zoology JF - American Journal of Zoology JO - American Journal of Zoology SP - 44 EP - 50 PB - Science Publishing Group SN - 2994-7413 UR - https://doi.org/10.11648/j.ajz.20190204.11 AB - DNA microarrays are technology that measure the expression level of thousands of genes at the same time. They need become avital tool for a good kind of biological experiments. one among the most common goals of polymer microarray experiments is to spot genes related to biological processes of interest. DNA Microarray is one such technology that allows the researchers to analyze and address problems that were once thought to be non traceable. This technology has scepter the scientific community to manage the elemental aspects underlining the expansion and development of life, additionally on explore the genetic causes of anomalies occurring within the functioning of organisms. Microarrays area unit vital as a result of they possess a large variety of genes and additionally owingto their transportable size. An important implication of the fundamental dogma of molecular biology is that there should be a strong association between the presence of a given protein in a cell and the presence of the mRNA sequence that is transcribed to build that protein. If a protein is active in a given cell, there should be a large number of copies of the mRNA sequence corresponding to that protein. Conversely, if a protein is not active in a cell, there should be few copies of the corresponding mRNA sequence. Thus, DNA microarrays attempt to evaluate the presence or absence of proteins in a cell and their relative abundance by measuring the relative abundance of the corresponding mRNA sequences. This review addresses the potential uses of DNA microarray technology, principle of the technology, its application and limitation of the technology. VL - 2 IS - 4 ER -
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