An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen

Yuri Pivovarenko

doi:doi:10.11648/j.bs.20170305.12

| Peer-Reviewed

An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen

Yuri Pivovarenko

Published in Biomedical Sciences (Volume 3, Issue 5)

Received: 17 August 2017 Accepted: 7 September 2017 Published: 10 October 2017

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

It is considered that the cause of some forms of cancer is the modification of DNA by active oxygen. This suggests that the removal of oxygen from the composition of such DNA will cure these forms of cancer. For the practical implementation of this idea proposed a number of substances that are harmless to humans, but have the ability to penetrate into cell nuclei and bind active oxygen.

Published in	Biomedical Sciences (Volume 3, Issue 5)
DOI	10.11648/j.bs.20170305.12
Page(s)	94-98
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Reactive Oxygen Species, ROS, Cancer, Oncology

References

[1]	Frenkel, K. (1992) Carcinogen-mediated oxidant formation and oxidative DNA damage. Pharmacol. Ther., 53, 127-166.
[2]	Poulsen H. E., Prieme H., and Loft S. (1998) Role of oxidative DNA damage in cancer initiation and promotion. Eur. J. Cancer Prev., 7(1), 9-16.
[3]	Bandyopadhyay U., Das D. and Banerjee R. K. (1999) Reactive oxygen species: Oxidative damage and pathogenesis. Current Science, 77(5), 658-666.
[4]	Cooke M. S., Evans M. D., Dizdaroglu M., and Linec J. (2003) Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J., 17(10), 1195-1214.
[5]	Khan F. and Ali R. (2005) Enhanced recognition of hydroxyl radical modified plasmid DNA by circulating cancer antibodies. J. Exp. Clin. Cancer Res., 24, 289-296.
[6]	Khan Fozia, Khan Farina and Ali R. (2007) Immunogenicity of DNA damaged by singlet oxygen: Implications in SLE and Cancer. Biotechnology and Applied Biochemistry, 46(2), 97-103.
[7]	Terentyeva Y. and Pivovarenko Y. (2015) UV absorbance of lymfocytes. European Journal of Advanced Research in Biological and Life Sinces, 3(4), 20-24.
[8]	Khan Fozia, Khan Farina, Siddicu A. A. and Ali R. (2006) Enhancement of immunogenicity of plasmid DNA under the action of singlet oxygen. Biochemistry (Russian edition), 71(8), 1074-1082.
[9]	Doshi R., Day P. J. R. and Tirelli N. (2009) Dissolved oxygen alteration of the spectrophotometric analysis and quantification of nucleic acid solutions. Biochem. Soc. Transactions, 37, 466-470.
[10]	Doshi R., Day P. J. R., Carampin P., Blanch E., Statford I. J. and Tirelli N. (2010) Spectrophotometric analysis of nucleic acids: oxygenation-dependant hyperchromism of DNA. Anal. Bioanal. Chem., 396, 2331–2339.
[11]	Pivovarenko, Y. V. (2014) Hypochromism degassed solutions of DNA Modern high technologies. 3, 147-150 (in Russian).
[12]	Shevchenko V. B., Datsenko A. I., Shablikin O. V., Osadchuk T. V., Lyakhov A. M., Pivovarenko Y. V. and Makara V. A. (2012) Definition of ROS in the presence of biologically active substances by porous silicon fluorescence. Ukrainian Biochemical Journal, 84(4), 67-7 (in Ukrainian).
[13]	Nekrasov B. V. (1974) Bases general chemistry, 1. Moscow: Chemistry (In Russian).
[14]	Peregud E. A. and Gernet E. B. (1973) Air Chemical Analysis of Industrial Plants. Leningrad: Chemistry (in Russian).
[15]	Wesson L. G. (1969) Physiology of the human kidney. New York: Grune and Stratton, 1.
[16]	Fadeeva V. K. (1971) Effect of drinking water with different chloride contents on experimental animals. Hygiene and sanitation, 36(6), 111-115 (in Russian).
[17]	Vladimirov Yu. A. (2004) Active forms of oxygen and nitrogen: implications for diagnosis, prevention and therapy. Biochemistry (Russian Ed.), 69(1), 5-7.
[18]	Shabarova Z. A., and Bogdanov, A. A. (1978) Chemistry of nucleic acids and their components. Moscow: Chemistry (In Russian).
[19]	Harchenko, N. V., Tchernenko, V. V., Tchervak, I. N., Stukalo, V. M., Tokar, D. V. (2008) Using Espumizan preparation in practice gastroenterologist. Ukraine’s Health, 6(1), 52-53 (in Ukrainian).
[20]	Shpolsky E. V. (1974) Atomic Physics, 1. Moscow: Nauka.
[21]	Kuchling H. (1980) Physik. Leipzig: VEB Fachbuchverlag.
[22]	Belovolova, L. V.; Glushkov, M. V.; Vinogradova, G. I., (2006) Features water fluorescence activated electrolysis. The role of reactive oxygen species. Electronic multidisciplinary scientific journal “Investigated in Russia” of Moscow Physic-Technical Institute, 268, 2588-2601. Available from: http://zhurnal.ape.relarn.ru/articles/2006/268.pdf. [Accessed: 24th March 2012] (In Russian).

Cite This Article

Plain Text BibTeX RIS

APA Style

Yuri Pivovarenko. (2017). An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen. Biomedical Sciences, 3(5), 94-98. https://doi.org/10.11648/j.bs.20170305.12

Copy | Download

ACS Style

Yuri Pivovarenko. An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen. Biomed. Sci. 2017, 3(5), 94-98. doi: 10.11648/j.bs.20170305.12

Copy | Download

AMA Style

Yuri Pivovarenko. An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen. Biomed Sci. 2017;3(5):94-98. doi: 10.11648/j.bs.20170305.12

Copy | Download

@article{10.11648/j.bs.20170305.12,
  author = {Yuri Pivovarenko},
  title = {An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen},
  journal = {Biomedical Sciences},
  volume = {3},
  number = {5},
  pages = {94-98},
  doi = {10.11648/j.bs.20170305.12},
  url = {https://doi.org/10.11648/j.bs.20170305.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20170305.12},
  abstract = {It is considered that the cause of some forms of cancer is the modification of DNA by active oxygen. This suggests that the removal of oxygen from the composition of such DNA will cure these forms of cancer. For the practical implementation of this idea proposed a number of substances that are harmless to humans, but have the ability to penetrate into cell nuclei and bind active oxygen.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen
AU  - Yuri Pivovarenko
Y1  - 2017/10/10
PY  - 2017
N1  - https://doi.org/10.11648/j.bs.20170305.12
DO  - 10.11648/j.bs.20170305.12
T2  - Biomedical Sciences
JF  - Biomedical Sciences
JO  - Biomedical Sciences
SP  - 94
EP  - 98
PB  - Science Publishing Group
SN  - 2575-3932
UR  - https://doi.org/10.11648/j.bs.20170305.12
AB  - It is considered that the cause of some forms of cancer is the modification of DNA by active oxygen. This suggests that the removal of oxygen from the composition of such DNA will cure these forms of cancer. For the practical implementation of this idea proposed a number of substances that are harmless to humans, but have the ability to penetrate into cell nuclei and bind active oxygen.
VL  - 3
IS  - 5
ER  -

Copy | Download

Author Information

Yuri Pivovarenko

Research and Training ‘Centre Physical and Chemical Materials Science’ Under NAS of Ukraine, Kiev, Ukraine

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Yuri Pivovarenko. (2017). An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen. Biomedical Sciences, 3(5), 94-98. https://doi.org/10.11648/j.bs.20170305.12

Copy | Download

ACS Style

Yuri Pivovarenko. An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen. Biomed. Sci. 2017, 3(5), 94-98. doi: 10.11648/j.bs.20170305.12

Copy | Download

AMA Style

Yuri Pivovarenko. An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen. Biomed Sci. 2017;3(5):94-98. doi: 10.11648/j.bs.20170305.12

Copy | Download

@article{10.11648/j.bs.20170305.12,
  author = {Yuri Pivovarenko},
  title = {An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen},
  journal = {Biomedical Sciences},
  volume = {3},
  number = {5},
  pages = {94-98},
  doi = {10.11648/j.bs.20170305.12},
  url = {https://doi.org/10.11648/j.bs.20170305.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20170305.12},
  abstract = {It is considered that the cause of some forms of cancer is the modification of DNA by active oxygen. This suggests that the removal of oxygen from the composition of such DNA will cure these forms of cancer. For the practical implementation of this idea proposed a number of substances that are harmless to humans, but have the ability to penetrate into cell nuclei and bind active oxygen.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - An Alternative Strategy in Cancer Chemotherapy, Aimed Not at Killing Cancer Cells, but the Recovery of Their DNA, Modified by Active Oxygen
AU  - Yuri Pivovarenko
Y1  - 2017/10/10
PY  - 2017
N1  - https://doi.org/10.11648/j.bs.20170305.12
DO  - 10.11648/j.bs.20170305.12
T2  - Biomedical Sciences
JF  - Biomedical Sciences
JO  - Biomedical Sciences
SP  - 94
EP  - 98
PB  - Science Publishing Group
SN  - 2575-3932
UR  - https://doi.org/10.11648/j.bs.20170305.12
AB  - It is considered that the cause of some forms of cancer is the modification of DNA by active oxygen. This suggests that the removal of oxygen from the composition of such DNA will cure these forms of cancer. For the practical implementation of this idea proposed a number of substances that are harmless to humans, but have the ability to penetrate into cell nuclei and bind active oxygen.
VL  - 3
IS  - 5
ER  -

Copy | Download